Clinical trials: Tobacco Smoking
Periodontal Diseases
The Role of Smoking in Periodontal Status
484 patients were asked whether they currently smoked and whether they had smoked 100 or more cigarettes during their lifetime. Based on this information, they were divided into two groups: current smokers (test group, n=242) and…
- Trial name
- TRSPS (NCT07295756)
- Testing
- Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 484 people, healthy volunteers welcome
- Sponsor
- Tuğba ŞAHİN
Tobacco-flavored EC, Sweet-Cooling EC
Electronic Cigarettes as a Harm Reduction Strategy Among People With Opioid Use Disorder on Buprenorphine
This project aims to investigate the impact of e-cigarette flavors and usage patterns on achieving harm-reduction milestones in a sample of cigarette smokers with opioid use disorder who are taking buprenorphine
- Conditions
- Tobacco-flavored EC, Sweet-Cooling EC, Sweet Non-cooling EC
- Trial name
- SWITCH (NCT07202039)
- Testing
- Brief individual counseling sessions
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Prisma Health-Upstate
Smoking Cessation
Adaptation and Initial Evaluation of Transdiagnostic CBT for Anxious and Depressed Smokers
This study will look at the effectiveness of a new treatment protocol for anxious and depressed smokers. Participants with clinically significant anxiety or depression will receive either the standard smoking cessation treatment…
- Trial name
- NCT03920137
- Testing
- UP-ST Therapy, Standard Therapy, Nicotine Patch
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Houston
Smoking Cessation
Effect of Self-administered Auricular Acupressure on Smoking Cessation-a Pilot Study
Auricular acupressure has been practiced in China and Germany to help people in smoking cessation programs. The purpose of this clinical trial is to test for the clinical effectiveness of self-administered auricular acupressure…
- Trial name
- NCT01389622
- Testing
- acupuncture
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Queen's University
Gingivitis
Angiogenesis in Periodontal Disease
Gum disease (gingivitis and periodontitis) is a common inflammatory condition affecting the tissues that support the teeth. Smoking is known to make gum disease worse and to affect blood vessel health in the gums.
- Trial name
- NCT07765251
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Inonu University
Smoking Cessation
Semi-personalized IM Smoking Cessation Interventions
Text messaging can provide smokers with quitting methods, information on available smoking cessation (SC) services and social support. This kind of intervention was proven to be effective for smoking cessation.
- Trial name
- NCT03574077
- Testing
- Instant Messaging (IM), AWARD advice, NRT sampling
- Where
- Hong Kong
- Volunteers
- 119 people
- Sponsor
- The University of Hong Kong
Smokers
D-Cycloserine Enhancement of Exposure-Based CBT for Smoking Cessation (DCSSmoking)
This study examines whether isolated doses of D-cycloserine enhance the efficacy of CBT for smoking cessation.
- Trial name
- NCT00827281
- Testing
- D-cycloserine
- Where
- United States
- Sponsor
- Boston University Charles River Campus
Smoking Cessation
Factors Related to the Intention to Quit Among Male Smokers During Their Wives Pregnancy
This study aims to use a cross-sectional study and semi-structured interview to explore the level of intention to quit smoking among male smokers whose partner got pregnant and further explore factors associated with their quit…
- Trial name
- NCT03401021
- Testing
- Questionnaires set
- Where
- Hong Kong
- Volunteers
- 466 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Smoking, Problem Drinking
A Medical Assistant-Based Program to Promote Healthy Behaviors in Primary Care
The purpose of the study is to determine whether a program of screening and intervention for four health risk behaviors (smoking, problem drinking, sedentary lifestyle, unhealthy diet) carried out by medical assistants in primary…
- Conditions
- Smoking, Problem Drinking, Sedentary Lifestyle, Unhealthy Diet
- Trial name
- NCT00273806
- Testing
- Intervention for 4 behavioral risks by medical assistants.
- Where
- 6 sites in United States
- Volunteers
- 864 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Electronic Cigarettes
Effects of e-Cigarettes on Nicotine Withdrawal
This behavioral pharmacology laboratory experiment will assess whether sweet (vs. non-sweet) flavored e-cigarette solutions reduce tobacco withdrawal symptoms and motivation to smoke among 40 smokers interested in trying…
- Trial name
- NCT03098004
- Testing
- e-Cigarette
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Smoking Cessation, Obesity and Obesity-related Medical Conditions
Clinical Research Evaluating Smoking Cessation With E-Cigarettes and Nicotine Therapy
This project will investigate the effects of alternative nicotine products on smoking, weight gain, and related outcomes.
- Trial name
- CRESCENT (NCT06948058)
- Testing
- Electronic Cigarettes (EC), Nicotine replacement therapy (NRT)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Brown University
Intervertebral Disc Degeneration
Smoking Effect on Lumbar Intervertebral Disc Degeneration
Besides normal aging, genetic and environmental factors are important potential determinants of lumbar disc degeneration. Smoking causes serious health problems, particularly lung and other cancers, heart disease and respiratory…
- Trial name
- NCT04702126
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 360 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Lung Cancer
Early Lung Cancer Detection in High Risk Individuals
The MILD project is a randomized lung cancer screening trial whose primary aim is to evaluate the impact on mortality of early lung cancer detection through LDCT (low-dose computed tomography) in 2 groups: a control group…
- Trial name
- MILD (NCT02837809)
- Testing
- Low dose CT
- Where
- Italy
- Volunteers
- 4,099 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Health Behavior
Effects of Electronic Cigarettes on Nicotine Concentrations
This study will examine whether nicotine levels increase with electronic cigarettes. It will also examine whether electronic cigarettes alter lung function tests.
- Trial name
- ECIG (NCT01775787)
- Testing
- Nicotine with Tobacco Flavor and Tobacco & Menthol Flavor
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- UConn Health
Cigarette Smoking-Related Carcinoma
Studying Different Ways of Using Oral Nicotine Pouches to Understand the Effect on Nicotine Delivery, Appeal, and Side Effects Among Adult Cigarette Smokers
This clinical trial studies how different ways of using oral nicotine pouches (ONPs) affect nicotine delivery, appeal, and side effects among adult cigarette smokers.
- Trial name
- NCT07899827
- Testing
- Biospecimen Collection, Oral nicotine pouches, Survey Administration
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Smoking, Veterans
Mobile Contingency Management for Smoking Cessation in Returning US Veterans
The primary goal of the study is to evaluate the effectiveness of a combined tele-health and contingency management (CM) intervention that the investigators call mobile CM, or mCM, in promoting smoking abstinence in US Veterans.
- Trial name
- NCT02513069
- Testing
- Nicotine gum, mobile contingency management, Telephone counseling
- Where
- United States
- Volunteers
- 291 people
- Sponsor
- Duke University
Tobacco Dependence
Nicotine Pharmacodynamics With a New Oral Nicotine Replacement Therapy and Nicotine Gum
A comparison of two products for oral nicotine replacement with respect to relief of urges to smoke after single doses of nicotine.
- Trial name
- NCT01368016
- Testing
- Nicotine
- Where
- 2 sites in Sweden
- Volunteers
- 346 people
- Sponsor
- McNeil AB
Nicotine Dependence
Assessment of Craving in Nicotine-Dependent Patients With Schizophrenia Using Virtual Reality
Background: The prevalence of cigarette smoking among individuals with schizophrenia is noticeably higher than in the general population, and smoking cessation attempts frequently are unsuccessful in this population.
- Trial name
- NCT01031433
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Inflammation, Oxidative Stress
Reduction of Exposure, Inflammation, and Oxidative Stress Following at Least 2 Years of Switching to THS Use Compared to Cigarette Smoking
This is a cross-sectional 3-group study with subjects enrolled and matched by region (Asia, Europe), age, sex, and average daily product consumption over the last 2 years as self-reported.
- Conditions
- Inflammation, Oxidative Stress, Smoking, Smoking Abstinence
- Trial name
- NCT05385055
- Testing
- THS use, Cigarette smoking, Smoking abstinence
- Where
- 37 sites in Bulgaria, Czechia and 4 more
- Volunteers
- 974 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Smoking, Healthy
Environments as Smoking Cues: Imaging Brain Substrates, Developing New Treatments (CameraCue)
The overarching goals of this proposal are to 1) identify the network of brain regions specifically activated by personal smoking environment cues and 2) to evaluate the effects of exposure to these cues on smoke…
- Trial name
- NCT01840111
- Testing
- Quit Smoking 6 hours, Quit Smoking 24 hours
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Duke University
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