Clinical trials: Tobacco Smoking
HIV, COPD
HIV+ Alveolar Macrophage Oxidant-mediated Apoptosis of Pulmonary Endothelium
In HIV+ cigarette smokers, with no prior history of pulmonary infections, emphysema is often developed at an earlier age and is a significant cause of morbidity despite treatment with antiretroviral drugs.
- Conditions
- HIV, COPD, Emphysema, Smoking
- Trial name
- NCT02056158
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Multiple Sclerosis
The Effect of Cigarette Smoke on Sleep Quality and Physical Activity in People With Multiple Sclerosis
Current evidence suggests that cigarette smoke increases disease progression in people with multiple sclerosis (PwMS) and worsen their symptoms. 70% of PwMS report sleep disturbances that negatively affects their quality of life.
- Trial name
- Smoke-MS (NCT05046535)
- Testing
- Sleep quality and physical activity, Nicotine dependence, Nicotine and cotinine serum levels
- Where
- Jordan
- Volunteers
- 72 people
- Sponsor
- University of Jordan
Chronic Obstructive Pulmonary Disease (COPD)
Smoking Cessation in Patients With COPD (SMOCC) in General Practice
Background: Smoking cessation is the key element in the treatment of patients with Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- SMOCC (NCT00628225)
- Testing
- Counseling and Nicotine replacement (CN), Counseling, Nicotine replacement and Bupropion (CNB)
- Where
- Netherlands
- Volunteers
- 667 people
- Sponsor
- ZonMw: The Netherlands Organisation for Health Research and Development
Tobacco Use Disorder
Project 2, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in Opioid Abusers
This study will examine extended exposure to cigarettes varying in nicotine content among adults with opioid use disorder. Those with opioid use disorder are at increased risk for smoking, nicotine dependence, and using high…
- Trial name
- P2S2 (NCT02250664)
- Testing
- Very low nicotine content cigarettes
- Where
- 2 sites in United States
- Volunteers
- 775 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Smoking Cessation
Using ICT to Deliver Brief Motivational Interviewing to Promote Smoking Cessation Among Smokers With Chronic Diseases
This study aims to evaluate the effectiveness of a general health promotion (GHP) approach using information communication technology (ICT) to deliver a brief motivational interviewing (MI) to motivate smokers with chronic…
- Trial name
- NCT03921606
- Testing
- Motivational Interviewing (i-BMI), Individual face-to-face generic health advice
- Where
- Hong Kong
- Volunteers
- 720 people
- Sponsor
- The University of Hong Kong
Smoking Cessation, Mental Illness
Mobile App for Smoking Cessation and Mental Health
Adults with serious mental illness (SMI) represent 5% of the United States population, yet account for 30% of all cigarettes smoked and are 2 to 3 times more likely to be dependent on nicotine compared with the general…
- Trial name
- NCT04887558
- Testing
- Smart-T Mental Health and NRT, Smart-T Mental Health+ and NRT, QuitGuide + NRT
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Chronic Obstructive Pulmonary Disease
Assessment of Ventilation-perfusion Abnormalities in Patients With Stable Smoking-related Airways Disease
Subjects undergo history, examination, lung function assessment after informed consent has been obtained. All subjects will undergo ventilation-perfusion scans.
- Trial name
- NCT00180843
- Testing
- salbutamol + ipratropium bromide nebules, nebulized saline
- Where
- United Kingdom
- Volunteers
- 2 people
- Sponsor
- Imperial College London
E-Cig Use
Understanding the Impact of Cartridge-Based Electronic Cigarettes and Generated Aerosols on Cardiopulmonary Health
Over the last decade, e-cigarettes have become increasingly popular, due to their promotion as a healthy alternative to traditional tobacco cigarettes.
- Trial name
- NCT05199480
- Testing
- Tobacco flavored liquid type 1, Tobacco flavored liquid type 2
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Pregnancy, Smoking Cessation
SmokefreeMOM: Reaching Pregnant Smokers With Health Information Via Text Messaging
Despite the great health benefits associated with smoking cessation in pregnancy to both mother and baby, few studies to date have examined the applications of text messaging or other communication technologies for smoking…
- Trial name
- SmokefreeMOM (NCT02412956)
- Testing
- SmokefreeMOM Text
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- George Washington University
Cigarette Smoking, Tobacco Smoking
Enhancing Smoking Cessation in the Homeless Population
The goal of this research study is to enhance smoking cessation rates for homeless smokers. The original study design proposed to test the effects of 1) an Intensive Smoking Intervention, and 2) integrating alcohol abuse…
- Conditions
- Cigarette Smoking, Tobacco Smoking, Smoking, Tobacco
- Trial name
- NCT01932996
- Testing
- nicotine patch plus nicotine gum/lozenge, Intensive Alcohol Intervention
- Where
- United States
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Vaping, Nicotine Dependence
Varenicline For Nicotine Vaping Cessation In Non Smoker Vaper Adolescents
The Investigators propose a randomized, placebo-controlled trial to test the hypothesis that varenicline added to group behavioral and texting support will be well tolerated and improve vaping cessation rates among nicotine…
- Trial name
- Pilot (NCT04602494)
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Massachusetts General Hospital
Smoking, Smoking Cessation
Preventing Relapse Following Involuntary Smoking Abstinence
The prevalence of tobacco use in the military is too high. This study is designed to take advantage of the 8.5 weeks of forced tobacco cessation during Basic Military Training and develop effective interventions to prevent…
- Trial name
- AFV (NCT01374724)
- Testing
- Tobacco Use Ban, Tailored Pamphlet, Informational Pamphlet
- Where
- 2 sites in United States
- Volunteers
- 23,000 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Smoking Cessation
Novel Treatment to Enhance Smoking Cessation Before Cancer Surgery
The purpose of this clinical trial is to determine the feasibility and efficacy of an intervention designed to increase rates of tobacco abstinence for cancer patients before their cancer surgery.
- Trial name
- NCT02402023
- Testing
- Contingency Management (CM), Standard of Care (SC)
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Yale University
Smoking, Heavy Episodic Drinking
Smoking Tobacco and Drinking Study
This trial will test the efficacy of a 3-month intervention on Facebook targeting tobacco use and heavy episodic drinking against a 3-month Facebook intervention targeting tobacco use.
- Trial name
- STAND (NCT03163303)
- Testing
- Tobacco Status Project Intervention, Tobacco Status Project + Alcohol Intervention, nicotine patch
- Where
- United States
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Lung Neoplasms, Pulmonary Disease, Chronic Obstructive
A Study of Smoking Cessation Patterns in Participants Undergoing Lung Surgery
The purpose of this study is to assess the current smoking status and smoking cessation attempts among smokers or recent smoking quitters during the perioperative period, to describe postoperative pulmonary complications (PPCs)…
- Trial name
- CHAMPION (NCT04313361)
- Testing
- No intervention
- Where
- 3 sites in China
- Volunteers
- 290 people
- Sponsor
- Johnson & Johnson (China) Investment Ltd.
Smoking, Smoking Behaviors
Take A Break - Rural
The study team proposes a multi-level trial to test 1) novel implementation programs in rural counties designed to increase access to 2) recent advances in tobacco control services for people who are not-yet-ready-to-quit…
- Conditions
- Smoking, Smoking Behaviors, Smoking Cessation
- Trial name
- TABR (NCT05790486)
- Testing
- Take a Break plus Nicotine replacement therapy (NRT) Sampling, The Comparison, Community Paramedicine Standard Plus Enhanced Implementation Program
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Smoking Cessation
Tobacco Education and Lung Health Study (TEAL)
Primary Objective To compare two smoking cessation interventions among individuals undergoing lung cancer screening. Primary outcomes are: 3-month self-reported abstinence from cigarettes and 6-month self-reported and bioverified…
- Trial name
- TEAL (NCT06290869)
- Testing
- Phone-based Tobacco Treatment, Nicotine Replacement, and Stepped Care Intervention, E-Referral to the Tobacco Quitline
- Where
- United States
- Volunteers
- 1,188 people
- Sponsor
- Georgetown University
Smoking Cessation
School-EduSmoke: A Cluster Randomized Controlled Trial for Promoting Smoking Cessation Among Parents of Schoolchildren
This study is a pragmatic two-group, multi-center, randomized controlled superiority trial, including an internal pilot, economic evaluation and process evaluation, aiming to assess the impact of a school-based comprehensive…
- Trial name
- NCT06853483
- Testing
- Family-School based smoking cessation intervention package
- Where
- China
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Multimorbidity, Tobacco Use Cessation
Impact of Multi-Component Interventions on High-Risk COPD Smokers
Study Participants: In our study, we focus on smokers who self-report a "current smoking" status or smoking cessation less than 6 months.
- Conditions
- Multimorbidity, Tobacco Use Cessation, Smoking Reduction
- Trial name
- POPMIX-Smoking (NCT06458205)
- Testing
- Multi-component intervention for smokers
- Where
- China
- Volunteers
- 4,247 people
- Sponsor
- Peking Union Medical College
Cigarillo Smoking
Cigarillo Public Education Messaging for Black Young Adults
This is a 3-arm randomized controlled trial to examine the effects of cigarillo public education messages among Black young adults who are at-risk for established cigarillo smoking.
- Trial name
- NCT06863168
- Testing
- Cigarillo Health Harm and Nicotine Addiction Messaging, Cigarillo Health Harm and Nicotine Addiction Messaging Contextualized to Outcome Expectancies
- Where
- 2 sites in United States
- Volunteers
- 360 people
- Sponsor
- Drexel University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.