Clinical trials: Tobacco Smoking
Nicotine Addiction, Cigarette Smoking
Abuse Liability of Reduced Nicotine Content Cigarettes in the Context of Concurrent E-Cigarette Use
Three hundred-twenty (320) adult smokers of menthol or non-menthol combustible cigarettes will be recruited and randomly assigned to one of five groups (n=64/group), who will be asked to switch for 12 weeks to ad libitum use of…
- Trial name
- DUAL (NCT02870218)
- Testing
- Smoking research cigarettes with e-cigarette, Nicotine discrimination thresholds
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Rose Research Center, LLC
Survey, E-Cig Use
Assessment of Smoking, Vaping, and Alcohol Consumption Behavior
To assess smoking, vaping, and alcohol consumption behaviors via online surveys in the population. Further, the objective is to administer additional surveys to assess which methods (e.g., pen-and-paper records, a smartphone app)…
- Conditions
- Survey, E-Cig Use, Smoking Behaviors, Alcohol Drinking
- Trial name
- NCT04150510
- Where
- United States
- Volunteers
- 3,245 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Smoking
A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse
This study evaluates the efficacy and safety of brenipatide when compared to placebo for reducing the risk of relapse to cigarette smoking in adults who have recently quit.
- Trial name
- RENEW-Smk-1 (NCT07223840)
- Testing
- Brenipatide
- Where
- 29 sites in United States, China and 1 more
- Volunteers
- 222 people
- Sponsor
- Eli Lilly and Company
Cigarette Smoking
Quit Smoking With Nicotine Patch and Exercise/Health Education (Females Only)
This research study is for FEMALE cigarette smokers who want to quit smoking. Participants will be provided with brief quit-smoking education at the beginning of the study and will receive the nicotine patch for 10 weeks, free of…
- Trial name
- QFH (NCT01522274)
- Testing
- Moderate intensity exercise, Health education
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Brown University
Smoking Cessation, Mindfulness
Mindfulness-based, Mobile Health (mHealth) Smoking Cessation Intervention in Vietnam
The goals of this a three-arm randomized controlled trial (RCT) is to evaluate the efficacy of mindfulness-based, culturally appropriate, and mobile phone-based smoking cessation intervention among Vietnamese adult male smokers.
- Conditions
- Smoking Cessation, Mindfulness, Telemedicine, Smoking
- Trial name
- NCT06228976
- Testing
- Mindfulness-based, smoking cessation focused text messages., Educational messages, Control messages
- Where
- Vietnam
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Hanoi University of Public Health
Smoking Cessation, Smoking
Evaluation of National Cancer Institute (NCI) Smoking Intervention Resources
This is an evaluative study of three National Cancer Institute (NCI) smoking cessation resources: specifically, the smokefree.gov and women smokefree.gov websites, and the CIS counseling phone calls.
- Conditions
- Smoking Cessation, Smoking, Nicotine Dependence
- Trial name
- NCI (NCT01342523)
- Testing
- CIS - telephone cessation quitline counseling, Lozenge - nicotine mini-lozenges, Emails - Brief smoking prevention messages
- Where
- United States
- Volunteers
- 1,034 people
- Sponsor
- University of Wisconsin, Madison
Stage III Oropharyngeal Squamous Cell Carcinoma, Stage IVA Oropharyngeal Squamous Cell Carcinoma
Reduced-Dose Intensity-Modulated Radiation Therapy With or Without Cisplatin in Treating Patients With Advanced Oropharyngeal Cancer
This randomized phase II trial studies the side effects and how well modestly reduced-dose intensity-modulated radiation therapy (IMRT) with or without cisplatin works in treating patients with oropharyngeal cancer that has…
- Conditions
- Stage III Oropharyngeal Squamous Cell Carcinoma, Stage IVA Oropharyngeal Squamous Cell Carcinoma, Stage IVB Oropharyngeal Squamous Cell Carcinoma, Stage IVC Oropharyngeal Squamous Cell Carcinoma
- Trial name
- NCT02254278
- Testing
- Cisplatin, IMRT 6 weeks, IMRT 5 weeks
- Where
- 222 sites in United States, Canada and 2 more
- Volunteers
- 316 people
- Sponsor
- NRG Oncology
Cigarette Smoking
Switching From Usual Brand Cigarettes to a Tobacco-heating Cigarette or Snus
To evaluate selected biomarkers of tobacco exposure and biomarkers of harm and assess quality of life measures in smokers randomly switched from their usual brand of cigarette to one of three test products: (1) a tobacco-heating…
- Trial name
- QoL (NCT02061917)
- Testing
- Tobacco-Heating Cigarette, Snus (Smokeless Tobacco), Tobacco-Burning Cigarette
- Where
- 5 sites in United States
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- R.J. Reynolds Tobacco Company
Smoking Cessation
Dissemination of Tobacco Tactics for Hospitalized Smokers
Nurse-administered smoking cessation interventions have been shown to be efficacious, but are seldom implemented due to lack of training and time.
- Trial name
- NCT01309217
- Testing
- Tobacco Tactics Intervention, Usual Care
- Where
- 6 sites in United States
- Volunteers
- 1,528 people
- Sponsor
- University of Michigan
Pulmonary Disease, Autonomic Dysfunction
Meditative Movement for COPD Symptoms in Non-Smoking Flight Attendants
This study will explore the a Qigong based exercise intervention, here referred to as Meditative Movement (MM), to ameliorate the symptoms associated with chronic obstructive pulmonary disease (COPD) and its co-morbidities.
- Conditions
- Pulmonary Disease, Autonomic Dysfunction, COPD
- Trial name
- MMforFA (NCT02612389)
- Testing
- Meditative Movement taught via DVD
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Smoking Cessation
Worksite Phone Counseling for Smoking Cessation
Social support is poorly understood but likely to influence outcomes of behavior change efforts. Social support may take a directive or nondirective approach.
- Trial name
- NCT02730260
- Testing
- Nondirective smoking cessation coaching, Directive smoking cessation coaching
- Where
- United States
- Volunteers
- 518 people
- Sponsor
- Washington University School of Medicine
Tobacco Use
Impact of Cigarette and E-cigarette Flavors on Adult Smoking Behavior
This study will investigate within-person changes in smoking behavior when current menthol smokers are switched to non-menthol cigarettes and either tobacco or menthol flavored e-cigarettes.
- Trial name
- NCT04009850
- Testing
- Cigarette Brand Switching, E-cigarette Flavor
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Yale University
Smoking Cessation
Effect of Smoking Cessation on Glycemic Control in Type 2 Diabetics
The goal of this observational study is to learn about the long-term effects of smoking cessation on glycemic control in type 2 diabetic patients The main question it aims to answer is: Does smoking cessation lower HbA1c in type…
- Trial name
- NCT06687213
- Testing
- Smoking cessation counselling group
- Where
- Egypt
- Volunteers
- 178 people
- Sponsor
- Assiut University
Cardiovascular Diseases, Heart Diseases
Lay-Led Smoking Cessation Approach for Southeast Asian Men
To develop a scientifically valid and ethnically approved, lay-led smoking cessation intervention for Southeast Asian men and women, i-e., those from Cambodia, Laos, and Vietnam.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Lung Diseases, Obstructive, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT00005720
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Smoking Cessation, Smoking, Tobacco
Path2Quit Tobacco Intervention For African Americans
The purpose of this research is to study a smoking cessation program for adult smokers in Northeast Ohio. The study will also look at how different people respond to the program.
- Trial name
- NCT03524482
- Testing
- SmokeFreeText, Path2Quit
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Smoking Cessation, Addiction
Evaluation of the Efficacy of Repetitive Transcranial Magnetic Stimulation (rTMS) Low-frequency on Craving in Smoking Dependence
The fight against smoking is a public health priority. Without help, fewer than 5% of des smokers are abstinent at 12 months after smoking cessation.
- Trial name
- rTMS TABAC (NCT02812810)
- Testing
- active rTMS
- Where
- France
- Volunteers
- 39 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Nicotine Dependence
Understanding How Cigarette Direct Mail Marketing Influences Smoking Behaviors Among High and Low Socioeconomic Status Young Adult Smokers
Background: Smoking is a major public health problem in the U.S. Almost a half a million Americans die from it in a year. One thing that contributes to why people smoke is the marketing of cigarettes.
- Trial name
- NCT02974582
- Testing
- Exposure to smoking advertising with coupon, Exposure to smoking advertising without coupons, Exposure to non health related images
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute on Minority Health and Health Disparities (NIMHD)
Child Exposure to Tobacco Smoke
A Program to Protect Young Children From Tobacco Smoke Exposure
The goal of this research project is to develop and evaluate an intervention to reduce young child tobacco smoke exposure
- Trial name
- NCT01335178
- Testing
- Intervention
- Where
- Israel
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Secondhand Exposure to Electronic Cigarette
Bystanders' Exposure to Electronic Cigarette Aerosol in Confined Settings
Objective of this study is to investigate the bystanders' exposure to e-cigarette emissions in controlled conditions in confined settings. Design: a cross-sectional experimental study developed in two settings: a car and a room.
- Trial name
- NCT04140617
- Testing
- Exposure to aerosol of electronic cigarette
- Where
- Spain
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Institut Català d'Oncologia
Cardiovascular Disease, Tobacco Use Disorder
Reduction of Smoking in Cardiac Disease Patients
This study evaluates the effect of smoking reduction vs usual care (quitting advice only) for individuals with peripheral arterial disease who smoke.
- Trial name
- NCT00469885
- Testing
- Nicotine replacement, Motivational counseling
- Where
- 2 sites in United States
- Volunteers
- 152 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
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