Clinical trials: Tocolysis
Premature Birth, Premature Labor
Trial of Magnesium Sulfate Tocolysis Versus Nifedipine Tocolysis in Women With Preterm Labor
Primary Hypothesis: Acute tocolysis (48 hours) using oral nifedipine is more effective than intravenous magnesium sulfate in prolonging pregnancy in women with preterm labor with intact membranes between 24 and 32 6/7 weeks'…
- Trial name
- NCT00306462
- Testing
- Magnesium sulfate
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Preterm Labor
Utrogestan Versus Nifedipine as Tocolysis for Preterm Labor: a Randomised Controlled Trial
RESEARCH HYPOTHESIS -Incidence of preterm delivery is lower in women treated with oral micronized progesterone (Utrogestan) as acute tocolysis agent compare to Nifedipine group with fewer maternal side effect
- Trial name
- UTROGESTAN (NCT01985594)
- Testing
- utrogestan, Nifedipine
- Where
- Malaysia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- nor zila hassan malek
Preterm Labor
Extended Release Nifedipine Treatment as Maintenance Tocolysis to Prevent Preterm Delivery
To evaluate the treatment efficacy and safety usig extended release nifedipine, as maintenance therapy to pregnant women who were hospitalized and treated for preterm labor until 34 weeks' gestation.
- Trial name
- NCT00525486
- Testing
- Nifedipine extended release
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Preterm Premature Rupture of Membranes
Magnesium Sulfate Versus Placebo for Tocolysis in PPROM
Study compares the outcomes of women between 26 and 32 wks gestation with rupture of membranes. Women randomized to receive tocolysis with magnesium sulfate x 48 hrs or placebo of saline IV x 48 hrs.
- Trial name
- NCT00463736
- Testing
- Magnesium sulfate
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Regional Obstetrical Consultants
Labor Preterm Requiring Hospitalization
Management of Acute Preterm Labor: Nifedipen Alone or Combined With Cildenafil Citrate
The aim of this study is to assess whether or not the emergency tocolytic effect of combined nifedipine and sildenafil citrate will have a superior effect over nifedipine alone in terms of inhibiting eminent preterm labor and…
- Trial name
- NCT02337881
- Testing
- nifedipen, Sildenafil
- Where
- 2 sites in Egypt, Saudi Arabia
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Al Hayat National Hospital
Nonreassuring Fetal Status
Acute Tocolysis With Terbutaline for Suspected Fetal Distress
The trial was to determine the effect of administrating subcutaneous terbutaline prior to emergency caesarean delivery for suspected fetal distress
- Trial name
- NCT05326269
- Testing
- Terbutaline
- Where
- Malaysia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Kemaman
Tocolysis With Nifedipine
Changes in Central Arterial Pressure of Normotensive Women Taking Nifedipine for Tocolysis
To determine the central blood pressure changes in normotensive women who are receiving nifedipine for uterine contraction suppression
- Trial name
- NCT02902354
- Testing
- Nifedipine for tocolysis
- Volunteers
- healthy volunteers welcome
- Sponsor
- St. Louis University
Obstetric Labor, Premature
Vaginal Indomethacin for Preterm Labor
Indometacin is a cyclooxygenase agent from the NSAID family that has been used to treat preterm contractions since the 70's by preventing the synthesis of prostaglandins.
- Trial name
- TOCOMED (NCT04404686)
- Testing
- Indomethacin, Nifedipine
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Preterm Birth
Pilot Study to Evaluate a Prototype Electronic Uterine Inhibitor to Prevent Preterm Contractions
Use an electrical-inhibition (EI)/uterine pacemaker device similar to an electrical heart pacemaker to deliver a weak electrical current to the human uterus that will rapidly and safely inhibit the unwanted premature uterine…
- Trial name
- NCT00212446
- Testing
- Electrical Intervention (EI)
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Preterm Delivery, Preterm Contractions
The Impact of Bryophyllum on Preterm Delivery
The purpose of this study is whether Bryophyllum is more effective and has less side effects than traditional labor inhibitors in preventing preterm delivery.
- Conditions
- Preterm Delivery, Preterm Contractions, Cervical Shortening
- Trial name
- NCT00163579
- Testing
- Bryophyllum
- Where
- Switzerland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Premature Rupture of Membrane
Magnesium Sulphate in Premature Rupture of Membranes
To assess the outcome of using magnesium sulphate on fetus and women with preterm premature rupture of membranes
- Trial name
- NCT05134688
- Testing
- Magnesium sulfate
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Assiut University
Preterm Delivery
Efficacy of Oral Progesterone and Vaginal Progesterone After Tocolytic Therapy in Threatened Preterm Labor
The purpose of this study is to determine efficacy of vaginal and oral progesterone after tocolytic therapy in threatened preterm labor
- Trial name
- NCT02989519
- Testing
- dydrogesterone, Micronized progesterone
- Where
- Thailand
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Sanpasitthiprasong Hospital
Tocolysis
Bryophyllum vs. Nifedipine
In a prospective, randomised study the efficacy and tolerability of bryophyllum p. (p.o) vs. nifedipine (p.o) will be proofed in a defined group of pregnant women with threatened preterm labour.
- Trial name
- NCT00391339
- Testing
- Bryophyllum p.
- Where
- Switzerland
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Weleda AG
Preterm Labour
Single Versus Combination Therapy in Acute Tocolysis
The purpose of this study is to compare the tocolytic efficacy, effectiveness and safety of Atosiban in comparison with the combination of Atosiban and Nifedipine together.
- Trial name
- NCT01429545
- Testing
- Atosiban, Atosiban and nifedipine
- Where
- 2 sites in United Arab Emirates
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Tawam Hospital
Labor Preterm Multiple
Tocolytic Therapy for Preterm Labor in Multiple Gestation
To compare the tocolytic efficacy oxytocin receptor antagonist (Atosiban) with that of calcium channel blockers (Nifedipine) among women with multiple gestation who present with threatened preterm labor.
- Trial name
- NCT02725736
- Testing
- Atosiban, Nifedipine
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center