Clinical trials: Tongue Diseases
Plaque, Dental
Anti-bacterial Clinical Study on Teeth, Tongue, Cheek, Gum, and Saliva
This 4-week clinical study was designed to examine the antibacterial efficacy of brushing with a 0.454% stannous fluoride toothpaste with potassium nitrate and pyrophosphate compared to a toothpaste containing 0.76% MFP (marketed…
- Trial name
- NCT06353165
- Testing
- Stannous fluoride toothpaste, Colgate Dental Cream
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Digestive Tract Diseases, Liver Diseases
Tongue Image Database and Diagnostic Model for Digestive Tract Disease Diagnosis
The tongue images of patients with gastrointestinal diseases and healthy people will be collected and the tongue image database will be established.
- Conditions
- Digestive Tract Diseases, Liver Diseases, Colorectal Disease, Gastric Diseases
- Trial name
- NCT05182983
- Testing
- Tongue images，coating on the tongue and clinical data
- Where
- China
- Volunteers
- 10,690 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Erythema Migrans, Post-Lyme Disease Symptoms
Comparison of Doxycycline and Cefuroxime Axetil for Treatment of Erythema Migrans: Clinical and Microbiological Outcome
Background: While doxycycline is a standard antibiotic for treatment of erythema migrans in Europe as well as in the USA, the effectiveness of cefuroxime axetil in the treatment of adult patients with erythema migrans has been…
- Trial name
- NCT01518192
- Testing
- doxycycline, cefuroxime axetil
- Where
- 2 sites in Slovenia
- Volunteers
- 544 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Ankyloglossia, Impairment of Speech
Effectivity of P1821, a Novel Tongue Strengthening and Endurance Enhancing Speech Flow Exercise
The P1821 initiative constitutes an innovative intervention specifically engineered to enhance tongue muscular strength and endurance.
- Conditions
- Ankyloglossia, Impairment of Speech, Slurred Speech
- Trial name
- NCT07719582
- Testing
- P1821
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dream Video LLC
Chronic Obstructive Pulmonary Disease
Decreased Tongue Strength is Related to Skeletal Muscle Mass in COPD Subjects
Background: Dysphagia is frequently observed in subjects with chronic obstructive pulmonary disease (COPD). But tongue strength has not been investigated yet in COPD subjects.
- Trial name
- NCT04761380
- Testing
- balloon-based tongue pressure measurement device
- Where
- Japan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Kindai University
Dental Malocclusion, Angle Class II
BRIUS Vs FFA Efficiency
The purpose of this study is to compare the Full Fixed Preadjusted appliances (regular braces) when to the BRIUS system.
- Conditions
- Dental Malocclusion, Angle Class II, Angle Class I, Crowding, Tooth
- Trial name
- NCT04347018
- Testing
- BRIUS
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Erythema Migrans
Patient's Pretreatment Expectations About Post-Lyme Symptoms
The investigators will focus on pretreatment expectations of patients with early Lyme disease manifested as erythema migrans with the aim of assessing the association between pretreatment expectations quantified with a…
- Trial name
- NCT03462329
- Testing
- Antibiotics (preferentially oral doxycycline 100 mg bid)
- Where
- Slovenia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Malocclusion, Angle Class II, Division 1
Clinical Evaluation of Bio-creative Therapy for En Masse Retraction of the Maxillary Anterior Teeth
The purpose of this study is to compare the effectiveness and efficiency of labial versus lingual biocreative therapy in achieving en masse retraction of the maxillary anterior teeth in subjects with class II malocclusion…
- Trial name
- NCT03239275
- Testing
- Biocreative therapy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Sjögren's Syndrome, Systemic Lupus Erythematosus
Objective Measurement With TCM Pattern for AIDDES
To explore the association with TCM pattern and TCM tongue diagnosis for Autoimmune disease and Dry eye syndrome.
- Conditions
- Sjögren's Syndrome, Systemic Lupus Erythematosus, Dry Eye Syndrome
- Trial name
- NCT04747288
- Testing
- Traditional Chinese Medicine pattern, Traditional Chinese Medicine tongue diagnosis, Heart rate variability
- Where
- Taiwan
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Anxiety Disorders
"Machine Learning Analysis of Lingual Colorimetry and MADRS Anxiety-Depression Score in Acupuncture Patients"
This observational study aims to assess the potential relationship between tongue colorimetry (using standardized photographic techniques) and anxiety-depression scores measured by the Montgomery-Åsberg Depression Rating Scale…
- Trial name
- ML_AcuTongue (NCT06899490)
- Where
- France
- Volunteers
- 466 people, healthy volunteers welcome
- Sponsor
- Dr Benoit Bataille
Tongue Coating, Oral Biofilm
Comparison of Three Tongue Cleaners for Removing Tongue Coating
This randomised three-period crossover study compared the effectiveness of three tongue-cleaning devices - a bristled tongue brush, a plastic tongue scraper and a metal tongue scraper - in removing tongue biofilm.
- Conditions
- Tongue Coating, Oral Biofilm, Oral Hygiene, Dental Plaque
- Trial name
- NCT07767721
- Testing
- Bristled tongue brush, Plastic tongue scraper, Metal tongue scraper
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Kent University
Malocclusion, Angle Class I
The Efficacy of Lingual Aligners in Adults.
The goal of this clinical trial is to test the effectiveness of lingual aligners in adults. The main question to answer is: Are lingual aligners effective in achieving desired and predicted tooth movements?
- Trial name
- NCT06050655
- Testing
- Lingual aligners
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Dysgeusia
Gustin Gene Polymorphism and 6-n-propylthiouracil (PROP) Taste
The investigators evaluate the possible association of PROP taste with gustin gene polymorphism rs2274333 (A/G), salivary zinc ion concentration and BMI.
- Trial name
- gustinprop (NCT01097915)
- Where
- Italy
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
CKD
The Tongue Features Associated With Chronic Kidney Disease
The Automatic Tongue Diagnosis System (ATDS) was developed to capture tongue images and extract features reliably to assist the diagnosis of TCM practitioners.This project will employ the ATDS verified to extract the tongue…
- Trial name
- NCT04708743
- Testing
- Automatic Tongue Diagnosis System
- Where
- Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- China Medical University, Taiwan
Influenza Infection
Effect of the Interferon Alpha Citizen by Sub-Lingual Way on the Humoral Immunizing Answer
Influenza vaccination reduces the morbidity and mortality associated with influenza infection in at risk groups including the elderly and individuals with an impaired immune response, but is not totally protective in all…
- Trial name
- GP-INFA (NCT00647465)
- Testing
- vaccine
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Otorhinolaryngologic Disease, Otorhinolaryngologic Neoplasm
Ultrasound Evaluation of Tongue Movements in Speech and Swallowing
This study will assess the use of ultrasound-a test that uses sound waves to produce images-as a diagnostic tool for evaluating speech and swallowing.
- Conditions
- Otorhinolaryngologic Disease, Otorhinolaryngologic Neoplasm, Pharyngeal Neoplasm, Polymyositis
- Trial name
- NCT00001167
- Where
- United States
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Burning Mouth Syndrome
Neurogenic Mechanisms in Burning Mouth Syndrome
Burning mouth syndrome (BMS) is characterized by a bilateral burning sensation in the anterior tongue, hard palate and lips in the absence of any clinical or laboratory findings.
- Trial name
- BMS17 (NCT00875537)
- Testing
- Capsaicin oral gel 0.025%, Capsaicin oral gel 0.01%
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Mouth Breathing
Lips and Tongue of Mouth Breathing Children
Purpose: to characterize the posture, tone and mobility of lips and tongue of mouth breathing children. Methods: 40 mouth breathing children, 26 (65%) male and 14 (35%) female, aging between 7 and 10 years old, were involved in…
- Trial name
- NCT01296828
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Obstructive Sleep Apnea
Inspire® Upper Airway Stimulation System
The purpose of this post-market study is to assess safety and effectiveness of Inspire Upper Airway System (UAS) in a commercial setting.
- Trial name
- RCT (NCT02675816)
- Testing
- Inspire® Upper Airway Stimulation (UAS) System
- Where
- 4 sites in Belgium, Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Inspire Medical Systems, Inc.
Periodontitis, Tongue Coating
The Effect of Tongue Cleaning in Periodontitis Patients
The aim of this study was to examine in periodontitis patients with visible tongue coating the changes in microbial load (aerobic and anaerobic) of the 14 day use of a tongue scraper versus the use of a regular toothbrush to…
- Trial name
- NCT02764060
- Testing
- Tongue scraper, Toothbrush
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven