Clinical trials: Tonsillectomy
Tonsillectomy
Postoperative Oral Corticosteroids Following Tonsillectomy
Tonsillectomy is one of the most common surgical procedures in the United States, and post-operative pain management is a challenge for otolaryngologists.
- Trial name
- NCT03352115
- Testing
- Prednisolone
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Peritonsillar Abscess
Peritonsillar Abscess: Aspiration Versus Tonsillectomy a Chaud
Peritonsillar abscess (PTA) has a relatively high incidence of 41 per 100,000/year in Denmark. In spite of that, there is no regional or national consensus on treatment of PTA.
- Trial name
- NCT03326661
- Testing
- Aspiration, Tonsillectomy a chaud, Penicillin V + metronidazol (Penicillin allergy: Clindamycin alone)
- Where
- Denmark
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Analgesic Adverse Reaction
Ketorolac Use in Pediatric Patients Undergoing Tonsillectomy
This prospective, randomized, double blinded study is designed to compare the bleeding rates of ketorolac vs. placebo when used for post tonsillectomy pain control in pediatric patients ages 2-18.
- Trial name
- NCT03453541
- Testing
- Ketorolac Tromethamine, 0.9% Normal Saline
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Tonsillectomy
Tonsillectomy Using BiZact Tonsilletomy Device
The purpose of this study is to describe how Bizact Tonsillectomy Device might affect operative time and intraoperative blood loss in pediatric patients undergoing tonsillectomy, and compare these parameters to the standard…
- Trial name
- NCT04320095
- Testing
- Bizact tonsillectomy device
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Sleep Apnea, Obstructive
Effect of Adenotonsillectomy on Quality of Life in Children With Mild Obstructive Sleep Apnea
In children, enlarged adenoids and/or tonsils are the most common cause of obstructive sleep apnea (OSA), which is temporary blockage of breathing during sleep.
- Trial name
- NCT01539278
- Testing
- Adenotonsillectomy, Observation alone / no intervention
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Postoperative Nausea and Vomiting
Dexamethasone Versus Local Infiltration Technique for Tonsillectomy in Children
Tonsillectomy is one of the most frequent surgical operations performed in children [1-4]. It is usually associated with postoperative nausea and vomiting (PONV) with an incidence ranging from 23% to 73% [2].
- Trial name
- NCT02355678
- Testing
- dexamethasone, Local anesthetic infiltration, General anesthesia
- Where
- Lebanon
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Makassed General Hospital
Hemorrhage, Pain
Effect of Tonsillar Pillar Closure on Postoperative Pain and Bleeding Risk After Tonsillectomy
The purpose of this study is to determine if closing the tonsil fossa after tonsillectomy leads to less pain and bleeding risk than leaving it open to heal by secondary intention.
- Trial name
- NCT00394849
- Testing
- suture one tonsillar fossa
- Where
- United States
- Volunteers
- 763 people, healthy volunteers welcome
- Sponsor
- Indiana University
Tonsillectomy, Adenoidectomy
Preoperative VR Cartoon Viewing Reduces Postoperative Pain and Anxiety in Pediatric Tonsillectomy Patient
The aim of this study is to determine the effect of watching a cartoon with a virtual reality headset before surgery on the pain and anxiety levels of children aged 7-12 years.
- Trial name
- NCT06763276
- Testing
- Virtual Reality Group
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Izmir Tinaztepe University
Endotracheal Cuff, Adenoidectomy Surgery
Effect of Neck Hyperextension on Endotracheal Tube Cuff Pressure in Children
Introduction: Patients undergoing surgery under general anaesthesia are frequently intubated with an endotracheal tube (ETT). The safety margin of ETT cuff pressure is between 20-30 cmH2O.
- Conditions
- Endotracheal Cuff, Adenoidectomy Surgery, Tonsillectomy with or Without Adenoidectomy, Position Differences
- Trial name
- NCT06767696
- Testing
- Cuff pressure measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Sleep Apnea, Obstructive, Respiration Disorders
Treatment of Children With Obstructive Sleep Apnea and Laryngomalacia: the Role of Laser Supraglottoplasty
This is a research study of the effect of treating laryngomalacia (floppiness of tissue on top of the voice box that can possibly block breathing) found in association with obstructive sleep apnea (blockage of breathing while…
- Trial name
- NCT00394550
- Testing
- supraglottoplasty with laser
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Indiana University
Tonsillitis, Tonsillectomy
SUPRATHEL 250 as a Treatment for Oropharyngeal Wounds
To assess the use of Suprathel 250 for mucosal reconstruction in oropharyngeal defects. The membrane will be applied after tonsillectomy procedures and compared to bare wounds' healing
- Conditions
- Tonsillitis, Tonsillectomy, Tonsillitis Recurrent
- Trial name
- NCT06543823
- Testing
- Suprathel 250, Comparator
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Alaa Emara
Tonsillitis
Effectiveness of Tonsil Fossa Closure in Pain Relief After Tonsillectomy in Children
Objective: Postoperative pain is the main complaint in children undergoing tonsillectomy. An inexpensive method and with few evidence in the literature on effectiveness in reducing pain is the closure of the tonsillar fossa by…
- Trial name
- NCT02676583
- Testing
- Tonsillectomy
- Where
- Brazil
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Marco Aurelio Fornazieri
Obstructive Sleep Apnea, Tonsillitis
Hydromorphone vs Fentanyl in Children Undergoing Tonsillectomy Surgery
A RCT to compare hydromorphone versus fentanyl for pain control following tonsillectomy or adenotonsillectomy surgery.
- Trial name
- NCT04230681
- Testing
- Hydromorphone, Fentanyl
- Where
- United States
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Endotracheal Tube Cuff Pressure, Adenotonsillectomy
The Changes of ETT Cuff Pressures After Head and Neck Positions Placed for Adenotonsillectomy and Tonsillectomy in Children
The main purpose of this study was to assess the effect of each of position (neck extension by under-shoulder pillow and Crowe-Davis retractor use) during adenoidectomy and adenotonsillectomy on the intracuff pressure of ETTs in…
- Conditions
- Endotracheal Tube Cuff Pressure, Adenotonsillectomy, Tonsillectomy, Position
- Trial name
- NCT05364281
- Testing
- Intracuff pressure measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Voice Quality, Tonsillectomy
Change of Nasalance After Tonsillectomy in Thai Adult
The purpose of this study is to analyze the change of nasalance after tonsillectomy in Thai adults.
- Trial name
- NCT01275079
- Where
- Thailand
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Anesthesia, Opioid Use
Opioid-Free Anesthetic for Tonsillectomy
Prospective randomized controlled trial to determine if opioid-free anesthetic for tonsillectomy is non-inferior to standard opioid-containing anesthetic
- Conditions
- Anesthesia, Opioid Use, Tonsillitis, Sleep Disorder
- Trial name
- NCT04528173
- Testing
- Ketorolac, Dexmedetomidine, Morphine
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Postoperative Pain
Intraoperative Methadone for Postoperative Pain in Patients Undergoing Tonsillectomy
A randomized controlled trial evaluating the efficacy and safety of single-shot intraoperative methadone for postoperative pain in patients undergoing tonsillectomy. Fentanyl is used as an active comparator
- Trial name
- METATONS (NCT05445856)
- Testing
- Methadone, Fentanyl
- Where
- Denmark
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Post Operative Analgesia, Tonsillectomy
Weight-Adjusted Diclofenac Potassium Medicated Lollipop for Post-Adenotonsillectomy Pain in Children
Brief Summary This study aimed to develop and conduct a preliminary clinical evaluation of a novel weight-adjusted gelatin-based diclofenac potassium medicated lollipop for the management of postoperative pain following…
- Conditions
- Post Operative Analgesia, Tonsillectomy, Pediatric Anesthesia
- Trial name
- DICLOPOP (NCT07646093)
- Testing
- Diclofenac Potassium Medicated Lollipop
- Where
- Venezuela
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario de Caracas
Tonsil Disease
Alternations in Body Composition of Tonsillectomy Patients During the Recovery Period
The body composition of individuals undergoing tonsillectomy is assessed through bioimpedance-based measurements conducted immediately before the surgery, as well as on the 7th and 21st days during the postoperative period.
- Trial name
- NCT06247436
- Testing
- Branch Chained Amino Acids
- Where
- Hungary
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Szeged University
Tonsillectomy
Suprazygomatic Nerve Block in Tonsillectomy Patients
The use of suprazygomatic maxillary nerve block to reduce postoperative pain and hospital stay is greater than the use of NSAID and opioids.
- Trial name
- NCT06359925
- Testing
- Suprazygomatic maxillary nerve block using dexmedetomidne and Bupivacaine, Suprazygomatic maxillary nerve block using Bupivacaine
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University