Clinical trials: Tonsillectomy
Pain, Postoperative, Postoperative Hemorrhage
Effect of Bupivacaine-infused Fibrin Sealant Application on Post-tonsillectomy Pain & Hemorrhage
The purpose of this study is to evaluate the effect of combining two interventions already in use at some institutions for reducing post-operative pain following tonsillectomy or adenotonsillectomy.
- Trial name
- NCT02343263
- Testing
- Bupivacaine, Fibrin Sealant
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Indiana University
Stress Response
Effect of Nebulized Lignocaine on the Stress Response of Endotracheal Intubation in Pediatrics Undergoing Tonsillectomy Operation Monitored by Rise in Serum Cortisol Level Post Intubation
This randomized clinical trial aims to is examining the effect of preoperative nebulized lidocaine on the stress response to intubation, monitored by rise in serum cortisol level post intubation
- Trial name
- NCT07139730
- Testing
- Lignocaine 2% concentration solution
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assiut University
Swallowing Impairment After Tonsillectomy
Evaluation of Swallowing Impairment After Tonsillectomy
the investigator will evaluate the swallowing pattern of the patients pre-operative and will follow them up at day 15 after tonsillectomy by using Careful history taking and Fiberoptic endoscopic evaluation of swallowing (FEES).
- Trial name
- NCT06927427
- Testing
- fiberoptic endoscopic evaluation of swallowing (FEES)
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Obstructive Sleep Apnea Syndrome
Ketamine Infusion for Pediatric Patients With Obstructive Sleep Apnea Syndrome (OSAS) After Tonsillectomy
The study will evaluate the post-operative morphine-sparing effect, pain reduction, and side effects of a continuous ketamine infusion after tonsillectomy in pediatric patients.
- Trial name
- KOSATA (NCT02425202)
- Testing
- Ketamine, Saline infusion
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Adenotonsillar Hypertrophy, Tonsillitis
Comparison of Floseal Hemostasis Tonsillectomy With Coblation Tonsillectomy and Cautery Hemostasis Tonsillectomy
The purpose of this study is to evaluate a new method of hemostasis, floseal gel, in tonsillectomy and adenoidectomy, with the goal of decreasing post operative and intraoperative morbidity.
- Conditions
- Adenotonsillar Hypertrophy, Tonsillitis, Obstructive Sleep Apnea
- Trial name
- NCT00459927
- Testing
- Floseal tonsillectomy, Coblation tonsillectomy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Tonsillectomy
Effect of Duration of Antibiotic Therapy on Recovery Following Tonsillectomy
To determine whether a 3-day course of postoperative antibiotics is effective as a 7-day course in reducing pain and reducing time to resumption of normal diet and activity following pediatric tonsillectomy
- Trial name
- NCT00662987
- Testing
- 7 days of amoxicillin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Pain, Postoperative, Tonsillar Hypertrophy
Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery in children and adolescents.
- Conditions
- Pain, Postoperative, Tonsillar Hypertrophy, Tonsillitis, Pediatric Sleep Apnea
- Trial name
- OPTIMAL (NCT06576830)
- Testing
- Methadone, Fentanyl/Hydromorphone
- Where
- United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Duke University
Obstructive Sleep Apnea, Enlargement of Tonsil or Adenoid
Caffeine in Children With Obstructive Sleep Apnea, Dose Response Study
The aim of this study is to evaluate whether a smaller dose of caffeine sodium benzoate 10 mg/kg IV is as effective as 20 mg/kg IV in decreasing the number of children who develop post extubation adverse upper airway respiratory…
- Trial name
- NCT01349205
- Testing
- Caffeine and sodium Benzoate 10 mg/kg IV, Caffeine and Sodium Benzoate 20 mg/kg IV, 0.9 NS Saline
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Tonsillar Surgery Complications
Complication Registry for Tonsil Surgery
Our aim was to establish a feasible method to prospectively register all tonsil surgery-related complications and to find their possible predictive factors.
- Trial name
- NCT02049372
- Where
- Finland
- Volunteers
- 794 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Postoperative Pain, Postoperative Nausea
Outcomes of Carbohydrate Loading Paediatric Patients Preoperatively for Tonsillectomy and Adenoidectomy
Randomised control trial of 150 paediatric patients aged between 3-8years. One group will receive a preoperative carbohydrate oral drink and the other group will receive current standard care (no drink) prior to undergoing…
- Conditions
- Postoperative Pain, Postoperative Nausea, Satisfaction, Sleep
- Trial name
- NCT03639012
- Testing
- Carbohydrate drink
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Jessica Gray
Post Surgical Pain, Analgesia
HONEY for the Treatment of POst-Tonsillectomy Pain
Double-blind, randomised, placebo controlled, single-site trial in adults to compare the effect of Manuka honey with standard of care compared to placebo with standard of care on post-tonsillectomy pain and postoperative…
- Trial name
- HONEY-POT (NCT06275698)
- Testing
- Manuka honey MGO 1000, Sugar-based syrup, thickened with sodium alginate and flavoured with honey flavouring
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- East and North Hertfordshire NHS Trust
Postoperative Pain
The Efficacy of Honey on Improving the Post Surgical Course After Tonsillectomy in Children-prospective Study
The aim of this study is to investigate the effect of honey administration on pain following pediatric tonsillectomy or adenotonsilectomy.
- Trial name
- NCT03296020
- Testing
- HONEY
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel