Clinical trials: Tooth, Impacted, open to volunteers
Stomatognatic, Tooth Diseases
Oral Specimen and Data Acquisition Study of Subjects Requiring Third Molar Removal
Background: The third molars (wisdom teeth) normally grow in during late adolescence or early adulthood. Many people need or choose to have these teeth removed with oral surgery.
- Conditions
- Stomatognatic, Tooth Diseases, Diseases, Tooth
- Trial name
- NCT01805869
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Dental Anxiety, Postoperative Pain
Effect of Alpha-Band Binaural Beats on Stress and Recovery in Third Molar Surgery
Preoperative anxiety and loud equipment noises, such as dental drills, create significant stress and autonomic fluctuations in patients undergoing oral surgery.
- Conditions
- Dental Anxiety, Postoperative Pain, Impacted Tooth, Binaural Beats
- Trial name
- NCT07881640
- Testing
- 10 Hz Alpha-Band Binaural Beats Track, Active Noise Cancellation (ANC)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Alperen Kalyoncu
Impacted Third Molar Tooth, Surgical Wound Healing
Antibacterial Effect and Soft Tissue Healing of Chlorhexidine-Coated Polyglactin 910 Sutures After Impacted Lower Third Molar Surgery
This study evaluates whether coating Polyglactin 910 sutures with chlorhexidine diacetate (CHX-DA) improves outcomes after the surgical removal of impacted mandibular (lower) third molars (wisdom teeth).
- Trial name
- NCT07794280
- Testing
- Chlorhexidine Diacetate-Coated Polyglactin 910 Suture, Uncoated Polyglactin 910 Suture
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Alveolar Bone Loss, Alveolar Ridge Resorption After Extraction
THBC/CGF for Alveolar Bone Regeneration: A Real-World Study
This study aims to combine real-world research with relevant bone repair materials and techniques to improve alveolar bone resorption in extraction sockets following impacted wisdom tooth removal, while achieving effective bone…
- Conditions
- Alveolar Bone Loss, Alveolar Ridge Resorption After Extraction, Tooth, Impacted
- Trial name
- NCT07779421
- Testing
- Temperature-sensitive hydroxybutyl chitosan-loaded concentrated growth factor, Temperature-sensitive hydroxybutyl chitosan, Autologous Concentrated Growth Factor
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Stomatological Hospital Affiliated with Fujian Medical University
Nasopharyngeal Carcinoma (NPC), Osteoradionecrosis of the Jaw
Impacted Tooth Management and Osteoradionecrosis Risk in NPC
This multicenter, randomized controlled trial is designed to determine whether omitting prophylactic extraction of impacted teeth before radiotherapy leads to an unacceptably higher risk of jaw osteoradionecrosis (JORN) compared…
- Trial name
- NCT07764887
- Testing
- Omission of Prophylactic Impacted Tooth Extraction, Prophylactic Impacted Tooth Extraction
- Where
- 11 sites in China
- Volunteers
- 536 people
- Sponsor
- First Affiliated Hospital of Guangxi Medical University
Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar
Comparison of PRF and Corticosteroids in Impacted Third Molar Surgery
This prospective, randomized interventional study aims to compare the postoperative effects of standard treatment (control), platelet-rich fibrin (PRF), and PRF combined with corticosteroid treatment in patients undergoing…
- Conditions
- Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar, Impacted Wisdom Tooth
- Trial name
- NCT07742826
- Testing
- Platelet-rich fibrin (PRF), Dexamethasone, Amoxicillin/Clavulanic Acid
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Final International University
Alveolar Bone Loss, Periodontal Pocket
Regenerative Gel (Emdogain®) for Healing After Wisdom Tooth Extraction
This study investigates whether the intraoperative application of a specialized regenerative gel (Emdogain®) can improve the periodontal health of the mandibular second molar by preventing or reducing the formation of tissue…
- Conditions
- Alveolar Bone Loss, Periodontal Pocket, Impacted Tooth With Abnormal Positioning
- Trial name
- NCT07718932
- Testing
- Enamel Matrix Derivative (Emdogain®)
- Where
- 2 sites in Greece
- Volunteers
- 70 people
- Sponsor
- Aristotle University Of Thessaloniki
Post Operative Pain, Impacted Third Molar Tooth
Jaw Muscle Pain Post Wisdom Molar Surgery
The proposed design is a triple-blind, placebo-controlled randomized prospective phase II trial to assess the feasibility of employing the Temporo-masseteric Nerve Block (TMNB) injection to decrease jaw muscle pain, overall pain…
- Conditions
- Post Operative Pain, Impacted Third Molar Tooth, Muscle Pain
- Trial name
- NCT07094542
- Testing
- Temporo-masseteric Nerve Block Injection, Oral Pain Medications only
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rutgers, The State University of New Jersey
Impacted Third Molar Tooth, Pain, Acute
Variability in Analgesic Response to Ibuprofen
Nonsteroidal anti-inflammatory drugs (NSAIDs), like ibuprofen, are recommended as first-line treatment for post-surgical dental pain.
- Trial name
- NCT06539741
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
TMJ, Apical Periodontitis
Application of a Dental-dedicated MRI in the Diagnosis of Temporomandibular Joint Disorders, Tissue Alterations Related to Third Molars, Periapical and Periodontal Inflammatory Diseases, and Implant Treatment Planning
The aim of the present study is to show that the use of 0.55T MRI combined with a "dental" coil produces images of sufficient diagnostic value to assess areas of interest in dentistry, and to compare MR images to traditional…
- Conditions
- TMJ, Apical Periodontitis, Periodontal Inflammation, Retained Tooth
- Trial name
- NCT05439330
- Testing
- MRI of teeth and surrounding structures
- Where
- Denmark
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Impacted Mandibular Third Molar, Postoperative Pain
"Effect of Preoperative Submucosal Dexamethasone on Postoperative Discomfort After Mandibular Third Molar Surgery"
This study aims to determine whether giving a single dose of dexamethasone before surgery can reduce pain and difficulty in opening the mouth after removal of an impacted lower wisdom tooth.
- Conditions
- Impacted Mandibular Third Molar, Postoperative Pain, Trismus
- Trial name
- DEXA-M3M (NCT07554963)
- Testing
- Dexamethasone, No intervention
- Volunteers
- 268 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Mandibular Diseases, Guided Surgery
Computer Guided Split Thickness Versus Full Thickness Flap Buccal Bone Lid Approach in Hard Mandibular Pathosis
Full thickness Buccal bone lid approach is well known and well reported technique with a superiority on preserving bone volume and better bone healing especially when done using piezoelectrical devices when compared to…
- Conditions
- Mandibular Diseases, Guided Surgery, Guided Surgery Accuracy
- Trial name
- NCT07338136
- Testing
- computer guided split thickness flap for buccal bone lid approuch
- Volunteers
- 26 people
- Sponsor
- Cairo University
Impacted Third Molar Tooth
Lidocaine Patch and Lower Third Molar
Completed medical and dental history will take for all patients and the position of the impacted teeth will evaluate by panoramic films.
- Trial name
- NCT07330726
- Testing
- Lidocaine patch
- Volunteers
- 21 people
- Sponsor
- Fayoum University
Tooth Avulsion, Dental Pulp Diseases
Optimizing Pulp Management in Autotransplantation of Mature Third Molars: A Randomized Controlled Trial
This study aims to find the best way to use your own healthy wisdom tooth to replace the bad tooth. After transplantation, how to manage the "tooth nerve" (dental pulp) inside the tooth is a key question.
- Conditions
- Tooth Avulsion, Dental Pulp Diseases, Tooth, Impacted
- Trial name
- OPuM-ATM3 (NCT07291531)
- Testing
- Postoperative Root Canal Therapy, Intraoperative Apical Surgery with Retrograde Filling, Intraoperative Root-End Resection
- Where
- China
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Facial Injuries, Mandible Fracture
Multi-Institutional IMPACT Validation
The goal of this observational study is to validate a novel patient-reported outcome measure (PROM) for patients suffering maxillofacial trauma: The Integrated Modular Patient-Reported Outcome Assessment for Craniomaxillofacial…
- Conditions
- Facial Injuries, Mandible Fracture, Le Fort, Zygomaticomaxillary Complex Fracture
- Trial name
- NCT06850857
- Testing
- IMPACT-G Module, IMPACT-N Module, IMPACT-O Module
- Where
- 3 sites in United States
- Volunteers
- 500 people
- Sponsor
- University of Tennessee
Impacted Third Molar Tooth
Local Metformin Gel and Impacted Lower Third Molar
Completed medical and dental history will take for all patients and the position of the impacted teeth will evaluate by panoramic films.
- Trial name
- NCT06975839
- Testing
- Metformin, non metformin gel
- Volunteers
- 36 people
- Sponsor
- Fayoum University
Impacted Third Molar Tooth
Assessment of Vertical Pattern in Correlation With Third Molar Inclusion : A 3D CBCT Analysis
The objective is to compare the sagittal and vertical skeletal parameters of patients with an impacted third molar. Patients will be analyzed according to their skeletal characteristics: skeletal class (sagittal direction) and…
- Trial name
- NCT06320665
- Testing
- Radiographic measurement
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Tooth Disease, Piezoelectric Technique
Comparison of Piezoelectric and Conventional Surgery for Germectomy of the Lower Third Molar
The main objective of the study is to compare the effects of the piezoelectric surgery and the traditional technique on soft tissue edema in patients undergoing bilateral germectomy of mandibular third molars
- Conditions
- Tooth Disease, Piezoelectric Technique, Tooth Impacted, Tooth Extraction Status Nos
- Trial name
- Germectomy (NCT06778590)
- Testing
- Piezoelectric technique in third molar germectomy, Traditional technique in third molar germectomy
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Amerigo Giudice
Oral Cancer, Health Education, Community
Testing and Comparing the Impacts of Mhealth-Based and Web-Based Education on Oral Cancer
Introduction: Oral cancer is a malignant neoplastic disease affecting the lip, oral cavity (mouth) and/or the oropharynx. Despite the intense and diverse public health interventions on oral cancer prevention, the global…
- Conditions
- Oral Cancer, Health Education, Community, Digital Intervention, MHealth Application
- Trial name
- NCT06711848
- Testing
- A web-based educational intervention on oral cancer, A mobile health app-based educational intervention on oral cancer
- Where
- 5 sites in India, Nigeria and 2 more
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Rwanda
Tooth, Impacted
Impacted Canine and Mixed-reality Technology - RCT
The goal of this clinical trial is to determine whether the use of HoloLens 2 mixed reality goggles for planning alignment of palatally impacted canine reduces: 1) treatment time and 2) the risk of complications compared to…
- Trial name
- NCT06574477
- Testing
- Planning of alignment with HoloLens 2, No planning of alignment with HoloLens 2
- Where
- Poland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Piotr Fudalej