Clinical trials: Tooth
Dental Caries, Tooth Wear
DIMOH: New Digital Methods for Monitoring Oral Health. An in Vivo Assessment
The objectives of this study are i) to monitor the oral health of young people over a period of one year and ii) to assess the ability of a new intraoral scanner combining fluorescence with 3D imaging to detect and monitor…
- Trial name
- NCT04050306
- Where
- 2 sites in Denmark, Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dental Caries, Dental White Spot
Effect of Light Curable Resin Modified Glass Ionomer Varnish on Non-Cavitated Proximal Carious Lesions' Progression
The standard-of-care preventive measures to stop early tooth decay from becoming worse is by fluoride application, diet counseling, and oral hygiene instructions. This standard way is not always successful.
- Trial name
- NCT03685058
- Testing
- Light curable resin modified glass ionomer varnish, standard-of-care preventive measures
- Where
- Saudi Arabia
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Alveolar Ridge Enlargement
Titanium Reinforced d-PTFE Membrane Versus Collagen Membrane For Guided Bone Regeneration
After tooth extraction, shrinkage of the bone is expected with 50% reduction of alveolar width. Patients at least 3months after tooth extraction and in need of single oral implant placement in the anterior maxilla with both…
- Trial name
- NCT05426616
- Testing
- collagen membrane (Creos Xenoprotect , Nobel Biocare AB, Göteborg, Sweden), titanium reinforced d-PTFE membrane (Creos Syntoprotect , Nobel Biocare AB, Göteborg, Sweden)
- Where
- 3 sites in Belgium
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Ghent
Tooth Loss
Clinical Assessment of Dental Implant
Primary Endpoints : The implant survival and success rate of V3 and C1 implants will be compared. Implant success rate will be evaluated by measuring the peri-implant bone remodeling from baseline to 1 year post insertion.
- Trial name
- H2015-1 (NCT02591706)
- Testing
- MIS Implants
- Where
- Belgium
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Liege
Crowding of Anterior Maxillary Teeth
Clear Aligner Treatment With and Without Low Level Laser Therapy for Upper Incisor Crowding
The goal of this clinical trial is to assess the effect of Low Level Laser Therapy (LLLT) on Upper Incisor Crowding using Clear Aligner Treatment (CAT).
- Trial name
- NCT06493721
- Testing
- Clear Aligner Treatment, Low level laser
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Dental Caries, Gingival Diseases
The Impact of Simple Home-based Differential Learning on Oral Hygiene in Children.
This randomized clinical trial study aims to investigate the impact of home-based differential learning on tooth brushing, in particular on the reduction of plaque and maintenance of gingival health in children aged 3 to 8 years…
- Trial name
- NCT04905784
- Testing
- Differential learning, Usual toothbrushing
- Where
- 2 sites in Germany
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Caries, Dental, Fluorosis, Dental
Dental Fluorosis Risk by the Use of Acidulated Fluoride Dentifrice
This research aimed to evaluate the risk of dental fluorosis by using an experimental fluoridated acidulated dentifrice compared to conventional dentifrices in two-to-four-year-old children residing in a non fluoridated area by…
- Trial name
- NCT03761485
- Testing
- Use of Dentifrice Fluoride
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Tooth Bleaching, Dentin Sensitivity
In-office Bleaching Using a Violet Light
The objective of this clinical study is to evaluate the effect of the whitening treatment performed with the violet LED light (405-410 nm), with or without a bleaching gel, on the tooth color changes (immediate and long-term)…
- Trial name
- NCT03207204
- Testing
- 35% Hydrogen peroxide bleaching, 30% Carbamide peroxide bleaching, Violet LED bleaching 1
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Nocturnal Bruxism
Efficacy of Phytolacca Decandra and Melissa Officinalis in Children With Nocturnal Bruxism
This study aims to evaluate, through a crossover, controlled, double-blind and randomized clinical trial, the efficacy of Phytolacca decandra in association or not with Melissa officinalis in the treatment of children with…
- Trial name
- NCT02870543
- Testing
- Phytolacca decandra, Melissa officinalis, Phyt.decandra + Melissa offic.
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Surface Hardness and Wear Resistance of Artificial Teeth
Surface Hardness and Wear Characteristics of Prefabricated and CAD/CAM Milled Artificial Teeth
Purpose: This study aimed to assess the 3-dimentional wear )3D) (volumetric loss) and 2-dimentional wear (2D) (vertical loss) and surface hardness of ready-made (prefabricated) and CAD/CAM milled artificial denture teeth.
- Trial name
- NCT06179615
- Testing
- surface hardness test for denture teeth, wear resistance of denture teeth measurement
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Malocclusion
Evaluation of Clear Aligner Trays to Straighten Teeth
The objective of this study is to evaluate the efficacy of Clear Aligners to correct tooth malocclusions with the use of attachments and/or buttons, as determined by the amount of teeth movement and overall achievement goals of…
- Trial name
- NCT03141788
- Testing
- Clear Aligner
- Where
- 9 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Solventum Orthodontics Corporation
Tooth Crowding
Effect of Corticotomy on the Orthodontic Tooth Movement
Orthodontic therapy allows for the treatment of dental malpositions in order to produce an adequate relationship between teeth during occlusion. Conventional orthodontic therapy applies slight forces and moves teeth slowly.
- Trial name
- NCT01630473
- Testing
- Corticotomy, Conventional orthodontics
- Where
- Colombia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Dental Caries, Periodontitis
Salivary IgA and Cytokines Response to Dietary Supplementation of Lactobacillus Reuteri
To evaluate the effect of daily ingestion of the probiotic Lactobacillus reuteri on the levels of secretory IgA and the cytokines Il1-beta, IL-6, IL-8 and IL-10 in saliva of healthy young adults.
- Trial name
- NCT02017886
- Testing
- L. reuteri DSM 17938/ATCC PTA
- Where
- Denmark
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dental Plaque
Evaluation of the Effect of Zinc Citrate Trihydrate Toothpaste on the Oral Plaque Microbiome
This study is of a double-blind, randomised, parallel group study. Subjects will be enrolled onto the study according to the inclusion/exclusion criteria.
- Trial name
- NCT06358742
- Testing
- ZCT toothpaste, Control toothpaste
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Pulpitis
Vital Pulp Therapy to Treat Irreversible Pulpitis
The purpose of this study is to demonstrate non-inferiority of pulpotomy treatment (with new endodontic bio-materials) as a new treatment with one-visit root canal therapy as reference treatment in pain relief and clinical and…
- Trial name
- VPT (NCT00748280)
- Testing
- One-visit root canal therapy, pulpotomy
- Where
- Iran
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Dental Plaque
A Study to Investigate the Antimicrobial Activity of 2 Test Toothpastes
The aim of this exploratory study is to assess the ability of two test toothpastes containing 0.6% w/w zinc chloride stabilised with sodium citrate in a sodium lauryl sulfate (SLS)-containing base to reduce glycolytic metabolism…
- Trial name
- NCT02856880
- Testing
- Test zinc-IPMP toothpaste, Test zinc non- IPMP toothpaste, Positive control
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Missing Tooth/Teeth
Abutment Hydrophilicity on Soft Tissue Morphogenesis
The goal of this clinical trial is to evaluate the effect of abutment surface bioactivation via argon plasma treatment on peri-implant soft tissue healing and integration in adult patients undergoing implant therapy.
- Trial name
- NCT07082088
- Testing
- the test group were placed in an Argon plasma reactor
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Paolo Pesce
Overbite (Excessive) Horizontal
Study the Effect of Upper Expansion Appliances on Lower Jaw Forward Projection/Growth
Young children with backward positioned lower jaw/chin will be recruited to have an upper jaw expansion appliance. Previous research showed that the use of similar appliances can lead to lower jaw forward growth.
- Trial name
- NCT03286569
- Testing
- Upper arch Wilson quadhelex appliance
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Root Caries
Silver Diamine Fluoride Treatment of Active Root Caries Lesions in Older Adults: A Case Series
The authors conducted a case series to determine the outcomes of treatment of root surface caries lesions when the teeth were treated topically with 38% silver diamine fluoride.
- Trial name
- NCT04370080
- Testing
- Silver Diamine Fluoride 38%
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Roseman University of Health Sciences
Dental Materials, Tooth, Nonvital
Fiber-reinforced Composite Core Filling in the Restoration of Endodontically Treated Molars - a Clinical Study.
A short fiber reinforced composite base filling material has been shown to improve the strength of a direct composite filling significantly. It prevents fracture propagation and reduces shrinkage strain.
- Trial name
- sFRCendocr (NCT04111003)
- Testing
- local anesthesia, Tooth restored using SFRC filling, Tooth restored using Ceramic indirect endocrown
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Turku