Clinical trials: Tooth Bleaching
Dental Hypersensitivity, Teeth Whitening
Effectiveness of 16% Carbamide Peroxide in Reducing Hypersensitivity During Alternate-day Home Bleaching
The concentration of 16% carbamide peroxide is the highest concentration that European regulations allow for use in home whitening (Council directive 2011/84/EU).
- Trial name
- NCT06035588
- Testing
- Daily whitening, Alternate whitening
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Dentin Sensitivity
Effect of Laser and Potassium Nitrate Application on the Sensitivity Control in Bleached Teeth
To investigate the effects of desensitizing agents on the dental bleaching process, testing the hypothesis that they may control dental sensitivity.
- Trial name
- NCT03434782
- Testing
- In-office dental bleaching, Low Level Laser Therapy, 5% potassium nitrate / 2% sodium fluoride gel
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Color, Bleaching Sensitivity
Whitening Efficacy and Tooth Sensitivity of Different Concentrations of Hydrogen Peroxide Photoactivated With Violet or Blue LEDs
This is a randomized, controlled, double-blind and repeated-measures clinical trial evaluated the photoactivation of hydrogen peroxide gels in different concentrations with blue or violet LED in terms of whitening efficacy and…
- Trial name
- NCT06165458
- Testing
- 6% hydrogen peroxide gel + violet LED, 6% hydrogen peroxide gel + blue LED, 35% hydrogen peroxide gel + violet LED
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Tooth Whitening, Sensitivity
Effects of Desensitizing Dentifrices on the Reduction of Pain Sensitivity Caused by In-office Dental Whitening
Introduction: The pain sensitivity associated with whitening is the main problem reported by patients during dental whitening, and the use of desensitizing dentifrices is an alternative for the treatment of sensitivity.
- Trial name
- NCT03019224
- Testing
- Selection and preparation of the volunteers, Evaluation of the tooth color, Relative isolation
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Tooth Discoloration
Efficacy of a Whitening Dentifrice on Tooth Discoloration
The purpose of this study was to compare the whitening effect of a toothpaste containing blue pigment with a conventional toothpaste and with at-home tooth bleaching; evaluate the subject's perception about tooth color…
- Trial name
- NCT02741427
- Testing
- Conventional toothpaste, Whitening toothpaste, 10% carbamide peroxide
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Dentin Hypersensitivity
Effect of Chemical and Light Bleaching Techniques on Color Change, Dentin Hypersensitivity and Patient Satisfaction
Aim of The Study This study aims is to evaluate color change, dentin hypersensitivity and patient satisfaction after different bleaching techniques at different time intervals.
- Trial name
- NCT07669324
- Testing
- Light activated bleaching, Chemically activated bleaching
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nahda University
Post Operative Pain
Efficacy of Desensitizing Agent,Propolis After an In-office Vital Tooth Bleaching.
This study was conducted to evaluate the efficacy of desensitizing agent Propolis, after an in -office vital tooth bleaching and to compare its desensitizing effect to traditionally used desensitizing agent fluoride varnish.
- Trial name
- NCT05569590
- Testing
- Propolis, hydrogen peroxide 35%, fluoride varnish
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Dentin Hypersensitivity
A Study to Investigate the Tooth Whitening and Dentin Hypersensitivity Effectiveness of Two Experimental Toothpastes
The aim of this exploratory clinical study is to investigate the tooth whitening potential, Dentin Hypersensitivity (DH) efficacy, and oral tolerability of two experimental toothpastes in a DH population with appropriate tooth…
- Trial name
- NCT07297732
- Testing
- Test Toothpaste 1, Test Toothpaste 2, Reference Toothpaste
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Sensitivity
The Strontium Chloride Associated With Photobiomodulation in the Control of Post-bleaching Sensitivity
This study investigated the effects of the association of strontium chloride with photobiomodulation on the dental bleaching process, testing the hypothesis that they may control dental sensitivity post-bleaching teeth.
- Trial name
- NCT04356911
- Testing
- FBM, ESTRÔNCIO, FBM+ESTRÔNCIO
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Dental Plaque, Gingivitis
Assessing the Effects of Three Oral Care Regimens
Assessing the effects of three oral care regimen on plaque, gingivitis, and tooth whitening: A randomized, person-centric, comparative effectiveness clinical research study by the Practitioners Engaged in Applied Research and…
- Trial name
- NCT02940821
- Testing
- Toothbrushing, Fluoridated Dentifrice (.15% sodium monofluorophosphate), Fluoridated Dentifrice Whitening System (.454% stannous fluoride with 2% hydrogen peroxide)
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Pearl Network
Tooth Bleaching, Pain
The Effect of an Experimental Gel Based on Acmella Oleracea Extract in Reducing Post-bleaching Tooth Sensitivity
This randomized, double-blind clinical trial aimed to evaluate the effect of an experimental gel containing 10% jambu extract (Acmella Oleracea) in reducing postoperative tooth sensitivity caused by bleaching with 35% hydrogen…
- Conditions
- Tooth Bleaching, Pain, Dentin Desensitizing Agents
- Trial name
- NCT05725850
- Testing
- EG (Experimental A. Oleracea extract gel)
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Removal of Toxicity From Dental Bleaching
NAC Prevents Toxicity of Teeth Bleaching
Dental bleaching is a simple procedure for aesthetic restoration of vital and non-vital discolored teeth. Nevertheless, a number of studies conducted previously demonstrated the risk of tissue damage from contact of these agents…
- Trial name
- NCT03534115
- Testing
- NAC
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Tooth Discoloration
Effects of Bio-active Desensitizer on Reduction of Tooth Sensitivity Caused by In-office Bleaching.
The main aim of this randomized controlled clinical trial is to evaluate the efficacy of a bioactive glass desensitizer in reducing tooth sensitivity associated with in-office vital tooth bleaching.
- Trial name
- NCT06532526
- Testing
- Predicta® Bioactive Desensitizer (PBD, PARKELL, EDGEWOOD, NY, USA), Gel with 1.23% sodium fluoride (EAZIGEL, VERICOM CO., LTD. SOUTH KOREA)
- Where
- Jordan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Tooth Discoloration, Color Changes During Tooth Formation
Office Bleaching Treatment by Using Rubber-cup and Air-powder Polishing Device Prophylaxis in Rondomised Clinical Design
The increasing demand for whitening teeth necessitates requirements and guidelines to ensure the efficacy of products and bleaching techniques.
- Trial name
- NCT04407910
- Testing
- AIRFLOW® Master device +Opalescence Xtra Boost., rubber-cup+Opalescence Xtra Boost.
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Tooth Discoloration, Tooth Staining
Peroxide Versus Non-Peroxide In-Office Tooth Bleaching
This randomized clinical trial aims to compare the effectiveness of peroxide and non-peroxide in-office tooth bleaching systems.
- Trial name
- BECTS (NCT07818031)
- Testing
- peroxide -based in office tooth bleaching, non-peroxide -based in office tooth bleaching
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Minia University
Hypersensitivity, Hypersensitivity, Immediate
Assessment of Er:YAG Laser for the Control of Hypersensitivity During Tooth Whitening With Hydrogen Peroxide
Introduction: Tooth whitening is an aesthetic procedure with rapid results that improves the self-esteem and self-image of patients. However, one of the side effects is dentinal hypersensitivity.
- Conditions
- Hypersensitivity, Hypersensitivity, Immediate, Hypersensitivity Response
- Trial name
- NCT06538129
- Testing
- Hypersensitivity prevention protocol with Er:YAG laser, Hypersensitivity prevention protocol with neutral sodium fluoride gel
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Tooth Bleaching, Tooth Sensitivity
Combined Bleaching Technique: Efficacy and Tooth Sensitivity
The aim of this clinical study is to evaluate the efficacy and dental sensitivity associated with Combined Bleaching Technique (in-office + at-home) varying in-office bleaching application under two different time protocols, and…
- Trial name
- NCT03089216
- Testing
- Combined Bleaching(2x20), Combined Bleaching(2x20) with arginine, Combined Bleaching (1x20)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Terezinha de Jesus Esteves Barata
Dentin Sensitivity
Longevity and Effectiveness of Bleaching in Healthy and Smokers Patients
The main objective of this study is to evaluate the effectiveness and longevity of color and Tooth sensitivity of patients undergoing home whitening peroxide 10% carbamide ( Whiteness Perfect , FGM , Joinville , Santa Catarina …
- Trial name
- BLESMOK (NCT02017873)
- Testing
- Peroxide Carbamide 10% - Dental bleaching treatment
- Where
- 2 sites in Brazil, Chile
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Chile
Tooth Discoloration, Tooth Sensitivity
At-home Bleaching Using Clear Retainers
The aim of this project is to clinically evaluate patient satisfaction, whitening efficacy, tooth sensitivity, and gingival irritation during at-home whitening with 10% carbamide peroxide using an Essix-type retainer or a Vivera…
- Conditions
- Tooth Discoloration, Tooth Sensitivity, Gingivitis, Satisfaction, Patient
- Trial name
- NCT05835453
- Testing
- Whitening
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Dentin Hypersensitivity
The Effect of Desensitizing Agents in In-home or In-office Dental Bleaching
The aim of this project is to evaluate in vitro and in vivo the effect of dental bleaching agents, carbamide peroxide 16% (T1) and hydrogen peroxide 35% (T2) together with desensitizers/remineralizer agents, Sensodyne® dentifrice…
- Trial name
- NCT02316080
- Testing
- Dental bleaching, Desensitizing therapy
- Where
- Brazil
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo