Clinical trials: Tooth Caries
Dental Caries
Effectiveness of SDF With Different Post-treatment Protocols in Arresting Dental Caries
To compare the effectiveness of the semi-annual application of 38% SDF with two post-treatment protocols in arresting dental caries in preschool children
- Trial name
- NCT05655286
- Testing
- 38% SDF treatment, not to rinse for at least 30 minutes after SDF treatment, rinse mouth immediately after SDF treatment
- Where
- China
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Dental Caries
Clinical Performance and Immediate Child and Parental Satis-faction With BioFlx Crowns in Primary Molars: A Prospective, Single-Arm, Non-Randomized Interventional Study
Informed consent was obtained from the parents/guardians of participating children after a detailed explanation about the treatment along with possible outcomes, risks, benefits, and discomforts is provided.
- Trial name
- NCT07471360
- Testing
- Bioflx pediatric dental posterior crowns
- Where
- Saudi Arabia
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Dental Caries
Glass Ionomer Sealant and Fluoride Varnish Study to Prevent Early Childhood Caries
The goal of this project is to conduct a community-based randomized clinical trial to compare the caries prevention efficacy of fluoride varnish applied every six months vs.
- Trial name
- GIFVT (NCT01129440)
- Testing
- Fluoride Varnish, Glass Ionomer Sealant
- Where
- United States
- Volunteers
- 597 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Paediatric Dentistry, Dental Caries in Children
The Success Rate and Acceptability of Conventional and Modified Hall Crowns Among Children and Parents
This is a clinical trial that aims to compare the success rate, child and parent acceptance of conventional Hall crown technique (CHT) to modified Hall crown technique (MHT)in treating carious primary molars.
- Conditions
- Paediatric Dentistry, Dental Caries in Children, Dental Treatment
- Trial name
- Hallcrowns (NCT06545279)
- Testing
- Hall Crown Technique, Modified Hall Technique
- Where
- Jordan
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Dental Caries, Child Behavior
Fluoride vs Probiotic Toothpaste for Caries Prevention
This clinical trial had two objectives. The first was to compare the effectiveness of 950 ppm fluoride toothpaste versus probiotic toothpaste in preventing dental caries in 4- to 5-year-old children.
- Trial name
- NCT07579403
- Testing
- Fluoride toothpaste, Probiotic Toothpaste, Control Toothpaste
- Where
- China
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital of Qingdao University
Caries,Dental, Dental Caries
The Impact of Sage Extract on GTS B and D Gene Expression in S. Mutans
Glucosyltransferases (Gtfs) play a crucial role in the pathogenesis of dental caries caused by Streptococcus mutans. Gtfs is recognized as an attractive target for effective therapeutic interventions aimed at inhibiting…
- Conditions
- Caries,Dental, Dental Caries, Dental Diseases
- Trial name
- NCT06703554
- Testing
- Sage Oil Mouthwash, Chlorohexidine Mouthwash
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Occlusal Bite Force Changes After Placement of Stainless Steel Crowns in Children
The aim of this study was to determine if restoring primary molars with SSCs would improve children's OBF.
- Trial name
- OBF (NCT03254069)
- Testing
- Stainless Steel Crowns
- Where
- Jordan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Preventive Oral Health
Oral Health Training Program for Pediatric Residents
The purpose of this study was to compare the effect of the addition of hands on training by a pediatric dentist on the pediatric residents skills, confidence, opinions and practice related to preventive oral health.
- Trial name
- NCT00846066
- Testing
- Hands on training, Web based training
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Dental Plaque, Behavior
The Impact of a 21day School Brushing Intervention on the Knowledge, Behaviour and Oral Health of School Children
In this study we aim to study the effectiveness of a specially designed 21 day Brush Day and Night programme for school children aged 6-9 which aims to establish the habit of twice a day toothbrushing for oral health.
- Conditions
- Dental Plaque, Behavior, Behavior, Health
- Trial name
- NCT04001296
- Testing
- 21 day Brush Day and Night school programme
- Where
- 2 sites in Indonesia, Nigeria
- Volunteers
- 2,020 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Dental Caries
Testing a Tooth Decay Prevention Program With Cree Mothers and Infants
Dental decay is an alarming problem in Cree children. The intervention is a behavioural counseling approach called Motivational Interviewing (MI).
- Trial name
- NCT00175318
- Testing
- Motivational Interviewing
- Where
- Canada
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Dental Caries
Clinical Study of Biosilicate Under Resin Composite Restorations in Caries Affected Teeth
This study aimed to evaluate the clinical performance of a novel vitro-ceramic biomaterial (Biosilicate®) as treatment of caries-affected dentin in posterior resin restorations.
- Trial name
- NCT02389569
- Testing
- Adhesive system, Restoration protocol
- Where
- Brazil
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Caries in Children
Success of Zirconia and Composite Strip Crowns for Primary Incisors
The purpose of this study is to evaluate and compare the clinical and radiographic performance of zirconia and composite strip crowns bonded on primary incisors
- Trial name
- NCT05034003
- Testing
- Zirconia crown, composite strip crown
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Caries,Dental
Fluoridated Milk and Enamel Caries in Adolescents
The goal of this trial is to investigate whether low daily doses of fluoridated milk, in addition to oral hygiene routines with fluoridated toothpaste, can prevent caries development in adolescents' teeth.
- Trial name
- NCT06684405
- Testing
- sodium sodium fluoride solution (0.75 mg for subjects aged 12 and 1.0 mg for subjects aged 13), Subjects in the control group received a daily dose of 0.5 ml sterile water to be added to 200 ml of milk.
- Where
- Sweden
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Malmö University
Dental Caries
Evaluation of Preventive Regimens With Different Toothpastes vs Fluoride Varnish & Toothpaste in High Caries Patients
This study will be conducted in order to determine the prevention effect of caries preventive regimen using herbal toothpaste and regimen using fluoride toothpaste versus fluoride toothpaste and fluoride varnish on the caries…
- Trial name
- NCT04436913
- Testing
- Himalaya complete care toothpaste, Signal toothpaste, Signal toothpaste and fluoride varnish
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University
Abrasion, Dental, Class I Dental Caries
Performance Of Class I Composite Restorations After Cavity Finishing By Air Abrasion Versus Diamond Stone
The aim of the study is to reveal the performance of the resin composite restorations after finishing the cavity walls and margins using bioactive glass air abrasion particles in comparison to the routine finishing with the…
- Trial name
- NCT06107218
- Testing
- Bioactive Glass Air Abrasion Particles., Diamond Stone.
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Effect of Erythritol and Xylitol on Dental Caries Prevention in Children
This study aims at demonstrating the effect of erythritol and xylitol lozenges on preventing the new caries lesions and the possible remineralization effect of both polyols on incipient caries lesions.
- Trial name
- NCT01062633
- Testing
- A, erythritol, xylitol, C, sorbitol
- Where
- Estonia
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Tartu
Dental Caries
Evaluation of Antimicrobial Efficacy of Green Tea, Garlic With Lime, Pomegranate Extract and Chlorhexidine Mouth Rinses in a Group of Egyptian Children (In-Vivo Study)
the aim of the clinical trial is to evaluate the antimicrobial efficacy of the herbal mouth rinses against chlorhexidine mouth rinse.
- Trial name
- NCT05841589
- Testing
- Green tea extract mouth rinse, Garlic with lime extract mouth rinse, Pomegranate extract mouth rinse
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- omnia sayed
Primary Teeth, Microbial Colonization
The Antibacterial Effect of Nanosilver Fluoride on Primary Teeth
To assess the antibacterial effect of Nanosilver Fluoride (NSF) in relation to caries activity in dentin caries lesions of primary teeth in comparison to Silver Diamine Fluoride (SDF).
- Conditions
- Primary Teeth, Microbial Colonization, Caries, Dental Caries in Children
- Trial name
- NCT05221749
- Testing
- Nanosilver Fluoride (NSF), Silver diamine fluoride
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nour Ammar, BDS
Dental Caries in Children
Evaluation of the Antimicrobial Fiber Reinforced Composite Resin Space Maintainer Modified With Silver Nano Particles
Fiber reinforced composite resin space maintainer
- Trial name
- NCT05902975
- Testing
- Fiber reinforced composite resin space maintainer
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Caries
Alkaline Water and Salivary Bacterial Count
This study will be aimed to examine the effect of alkaline water on salivary streptococcus mutans bacteria which is the main cause of dental caries and comparing its effect with chlorohexidine mouthwash on the children aged…
- Trial name
- NCT06511336
- Testing
- Alkaline water (FLO water- Bottled drinking water- the Egyption Saudi Company for natural water- made in Egypt
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pharos University in Alexandria