Clinical trials: Tooth Caries
Dental Caries, Dental Erosion
Maintaining Oral Health With Bio-products
This study will follow a randomised, double-blind, cross-over design. Participants will use mouth rinses containing plant extracts and/or fluoride, as well as a mouth rinse containing only water (placebo).
- Trial name
- NCT04033263
- Testing
- Mouth rinse 1, Mouth rinse 2, Mouth rinse 3
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Bern
Toothbrushing, Dental Plaque
BEhavioral EConomics for Oral Health iNnovation Pilot Trial
This Phase I randomized pilot trial will assess the efficacy of a fixed incentive payment program and drawing incentive payment program versus a control program to promote early childhood caries (ECC) preventive health behaviors…
- Conditions
- Toothbrushing, Dental Plaque, Parent-Child Relations, Oral Hygiene
- Trial name
- BEECON Pilot (NCT03862443)
- Testing
- Fixed Incentive, Drawing Incentive
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dental Caries, Gingivitis
Interdental Microbiota Among Adolescents
Adolescence remains a period during which tooth decay is still very active. There are few epidemiological studies in adolescents, and the majority of them were young people aged 15 and under.
- Trial name
- MIARC (NCT03700840)
- Testing
- Interdental brushes
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Université Montpellier
Dental Caries
Efficacy of Dentifrices Containing Arginine Versus Fluoride on Microbial Acid
This study will be conducted to evaluate the effect of arginine versus fluoride containing toothpaste on neutralization of microbial acid produced by Cariogenic bacteria in adult population using chair side assessment method.
- Trial name
- NCT03143023
- Testing
- arginine toothpaste, fluoride toothpaste
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries in Children
Discoloration of Carious Primary Teeth After Application of Silver Diamine Fluoride Versus Sodium Fluoride Varnish
To assess discoloration of carious primary teeth after application of silver diamine fluoride versus sodium fluoride varnish.
- Trial name
- NCT03557996
- Testing
- Silver Diamine Fluoride, Sodium Fluoride Varnish
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Carious Lesion, Restoration
Clinical Performance of Novel Coconut Based Restorative Material.
A triple-blind, parallel group, randomized trial with an allocation ratio of 1:1. Participants randomly allocated into two groups A and B.
- Trial name
- NCT07640074
- Testing
- Nano-reinforced glass ionomer, glass ionomer without nanoparicles
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Pulpitis - Irreversible, Tooth Decay
Efficacy of PRF and MTA as Compared to Calcium Hydroxide for Pulpotomy in Human Irreversibly Inflamed Permanent Teeth
Of all the various pulpotomy medicaments that have been studied till to date, three agents have been selected for this study to compare their efficacy.
- Trial name
- NCT05266859
- Testing
- Calcium hydroxide, MTA, PRF
- Where
- Pakistan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Liaquat College of Medicine and Dentistry
Dental Caries
Investigation of the Effect of Deep Margin Elevation Technique on the Clinical Performance of Endocrown Restorations Produced by Computer-Aided Design and Computer-Aided Manufacturing (CAD/CAM) System
The aim of this clinical study is to investigate the impact of the deep margin elevation technique on the clinical performance of CAD/CAM endocrown restorations in deep Class II cavities.
- Trial name
- NCT06222918
- Testing
- Deep Margin Elevation (G-ænial Universal Injectable)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Child Behavior, Dental Caries in Children
Sedation Versus Protective Stabilization for Pediatric Dental Treatment
There is a lack of evidence on the effectiveness of moderate sedation in pediatric dentistry, compared to protective stabilization, which remains routinely used in the Brazilian context despite moral questions.
- Trial name
- NCT04119180
- Testing
- Ketamine 50 MG/ML, Midazolam Hcl 2Mg/Ml Syrup, Protective stabilization
- Where
- 2 sites in Brazil
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Dental Caries in Children
Application of SDF Verses NaF Varnish in Treatment of Carious Primary Teeth
The aim of this study is to assess the postoperative pain after application of silver diamine fluoride versus sodium fluoride varnish in treatment of carious primary teeth.
- Trial name
- NCT03554980
- Testing
- Silver Diamine Fluoride, Sodium Fluoride varnish
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Clinical Performance Evaluation of a Glass-ionomer Restorative System Evaluation
The aim of this clinical trial was to compare the clinical performances of a glass ionomer restorative system with a micro hybrid resin based composite in class I and class II cavities.
- Trial name
- NCT03822403
- Testing
- EQUIA, Gradia Direct Posterior
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries
Evaluation of the Clinical Performance of Reinforced Glass Ionomer Restorations
This study is conducted to evaluate the clinical performance of class I reinforced glass ionomer restorations (Zirconomer Improved and Equia Forte Fil)
- Trial name
- NCT04288791
- Testing
- Equia Forte Fil, Zirconomer Improved
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Caries, Secondary Dental Caries
A Comparative Study of Papacarie® and the Conventional Method for Dental Caries Treatment
The purpose study are to evaluate the efficacy of Papacarie® for caries removal in comparison to the conventional drilling method.
- Conditions
- Dental Caries, Secondary Dental Caries, Personal Satisfaction
- Trial name
- NCT01641861
- Testing
- Papacarie®, Conventional method
- Where
- Thailand
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Dental Caries
Occlusal Bite Force Changes After Placement of Stainless Steel Crowns in Children
The aim of this study was to determine if restoring primary molars with SSCs would improve children's OBF.
- Trial name
- OBF (NCT03254069)
- Testing
- Stainless Steel Crowns
- Where
- Jordan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Class II Dental Caries
Comparison of Bulk-Fill Composite Resins in Class II Restorations
The goal of this clinical trial is to evaluate the clinical performance of Class II restorations of a thermoviscous nanohybrid materials , of a bulk-fill composite resin, and of conventional nanohyribrid bulk-fill composite…
- Trial name
- NCT06212141
- Testing
- VisCalor Bulk,VOCO,Germany, Admira Fusion x-tra,VOCO,Germany, Filtek One Bulk,3M,Germany
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Caries, Dental, Cariostatic Agents
Reducing Bacteria That Cause Tooth Decay
The purpose of the study is to determine the effect of a two-step mouth rinsing procedure on reducing the germs (mutans Streptococci) that cause tooth decay.
- Trial name
- NCT03062605
- Testing
- Iodine (Betadine), NaOCL
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Vitamin D Deficiency, Dental Caries
Maternal Vitamin D Levels in Pregnancy and Dental Caries in Children
The main aim of this study is to investigate potential associations between maternal pre- and postnatal vitamin D level and oral health outcomes (caries and developmental defects of enamel) in their children at 7-9 years of age.
- Conditions
- Vitamin D Deficiency, Dental Caries, Dental Enamel Hypoplasia
- Trial name
- NCT03273725
- Testing
- Dental examination including taking a saliva sample.
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Tannhelsetjenestens Kompetansesenter Midt-Norge
Deep Caries, Pulp Exposure, Dental
Evaluation of Conservative Management of Teeth With Deep Cavitated Carious Lesions
The goal of this clinical trial is to compare postoperative pain of calcium silicate cement and resin-based tricalcium silicate (TheraCal LC) versus chemically Cured Glass Ionomer cement (FujiXI) in conservative management of…
- Trial name
- NCT06171776
- Testing
- RetroMTA, TheraCal, Fuji IX
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Yakima Head Start Fluoride Varnish Study
The aim of this study is to determine whether an annual application of three (3) fluoride varnish doses over two weeks is at least as effective in reducing cavities as the current semi-annual application.
- Trial name
- NCT00067353
- Testing
- Fluoride varnish
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Washington
Dentin Caries
Evaluation of the Remineralizing and Antibacterial Effect of Natural Versus Synthetic Materials on Deep Carious Dentin
The present study will be performed to evaluate: 1. The remineralizing effect of natural materials versus synthetic materials on deep carious dentin after selective caries removal. 2.
- Trial name
- NCT04145102
- Testing
- hesperidine, propolis, silver diamine fluoride
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University