Clinical trials: Tooth Caries
Dental Caries of Root Surface, Surgery
Intraoral Imaging at Clinical Crown Lengthening
Crown lengthening surgery is done when a tooth needs to be fixed with a crown. Sometimes, not enough of the tooth sticks out above the gum to support a crown.
- Trial name
- NCT03064217
- Testing
- Making impression at surgery
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Dental Caries in Children
Effectiveness of Silver Diamine Fluoride in Arresting Dental Caries
The present study aims to evaluate, through a controlled clinical randomized study,the effectiveness of silver diamine fluoride in arresting dentin caries lesions in primary molars when compared to atraumatic restorative…
- Trial name
- NCT03063307
- Testing
- Atraumatic Restorative Treatment, Silver Diamine Fluoride
- Where
- Brazil
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Class I Dental Caries
Clinical Performance and Wear Resistance of Two Nano Ceramic Resin Composite in Class I Cavities
in patients with Class I Cavities, will the use of Zenit Nano Ceramic Composite restorations have similar clinical performance to conventional Ceram-X Nano Ceramic Composite restorations, evaluation of restorations will be done…
- Trial name
- NCT04738604
- Testing
- Ceram•X (Dentsply De Trey GmbH, Konstanz, Germany, Zenit Nano Ceramic Composite (PRESIDENT DENTAL, GmbH, Munich, Germany)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Quality of Life
Impact of Two Recall Intervals on Dental Caries Incidence and Other Outcomes of Preschool Children
Objectives: To assess the beneficial and harmful effects of two recall intervals on caries incidence (primary outcome) in preschool children with high caries risk.
- Conditions
- Dental Caries, Quality of Life, Anxiety
- Trial name
- NCT02537184
- Testing
- Oral Clinical conditions
- Where
- Brazil
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Caries
DPBRN Development of a Patient Based Provider Intervention for Early Caries Management
This study focused on improving the quality of dental care by fostering movement of the latest scientific advances into daily clinical practice.
- Trial name
- NCT01309958
- Where
- 7 sites in United States, Denmark
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Dental Practice-Based Research Network
Caries; Initial, Caries Active
Clinical Effectiveness of Bioactive Silica Based With Calcium Toothpaste
This study will be conducted to Clinically evaluate Bioactive Silica Based with calcium booster (Refix technology) toothpaste and Sodium Fluoride varnish versus conventional fluoride toothpastes in management of white spot…
- Trial name
- NCT07120243
- Testing
- Toothpaste Product, Varnishes, Fluoride
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rawda Hesham Abd ElAziz
Dental Caries, Pulpotomy
Comparison of Clinical Success of Stainless Steel Crowns and Zirconia Crowns in Primary Molars
Evaluation and understanding of clinical success, parental satisfaction and effects on periodontal tissues are the main expected benefits of prefabricated zirconia crowns and prefabricated stainless steel crowns.
- Trial name
- NCT06685640
- Testing
- prefabricated stainless steel crowns, prefabricated zirconia crowns
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Class II Dental Caries
Class II Restoration Using Bioactive Restorative Material vs Polyacid Modified Composite Resin in Primary Molars
Successful restoration of cavities in primary molars can be considered challenging. It is different from restoring cavities in permanent molars because factors such as the level of co-operation of the child and the handling…
- Trial name
- NCT04030117
- Testing
- ACTIVA Bioactive restoration, Compomer restoration
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Wear, Dental Decay
Effect of Modeling Resin on Anterior Direct Composite Veneer
the study will be conducted to evaluate the clinical performance of direct Nanohybrid resin composite veneer restorations applied with or without modeling resin
- Trial name
- NCT06485024
- Testing
- Modeling Resin
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Preventing Early Childhood Caries With Silver Diamine Fluoride
Background: Silver diamine fluoride (SDF) solution is effective in arresting early childhood caries (ECC). Previous studies suggested that it might exert a preventive effect in managing ECC.
- Trial name
- NCT04075474
- Testing
- silver diamine fluoride, sodium fluoride
- Where
- Hong Kong
- Volunteers
- 730 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Clinical Evaluation of the Efficacy of SPR-G Barrier Coat Versus Fluoride Varnish Versus MI Paste in the Treatment of Early White Spot Lesions in Pediatric Patients
In-Vivo randomized clinical trial to compare between the clinical performance of fluoride varnish versus MI paste (CPP_ACP) and the PRG- Barrier coat material concerning enamel remineralization, arrest of active early lesions…
- Trial name
- NCT05202821
- Testing
- PRG Barrier Coat, Fluoride varnish, MI paste
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Caries in Children
The Impact of Anticipatory Guidance on Early Childhood Caries: a Quasi-experimental Study
This study aimed to compare the impact of anticipatory guidance on the caries incidence of 2-3-year-old preschool children and their 4-6-year-old siblings, as well as on their mothers' oral health literacy, as compared to the…
- Trial name
- NCT03478748
- Testing
- Dental health education
- Where
- Malaysia
- Volunteers
- 478 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Dental Caries on Pit and Fissure Surface
Using ICDAS II and KaVo DIAGNOdent Pen Detecting Tooth Pit and Fissure Level Incipent Caries Progression
The study was to monitor effectiveness of glass ionomer sealant and resin-based sealant in ICDAS, and to evaluat the correlation between ICDAS and DIAGNOdent over 24 months.
- Trial name
- NCT03077035
- Testing
- glass ionomer sealants, resin-based sealant
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sheng-Chao Wang
Parenting, Cavity, Dental
Brief Interventions to Improve Behavior Outcomes and Prevent Cavities
The investigators will study brief educational interventions designed to address childhood behavior problems and prevent cavities.
- Conditions
- Parenting, Cavity, Dental, Child Behavior
- Trial name
- NCT06588725
- Testing
- Play Nicely, Cavity Prevention Handout
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Cardiac Disease, Dental Caries
Saliva Profiles in Children With Congenital Heart Disease
The purpose of this study was to evaluate whether there are relationships between the salivary oxidative stress status of children with CHD directly dental caries including gender, age, salivary flow rate, salivary pH, salivary…
- Trial name
- NCT03457974
- Testing
- saliva
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Decay, Dental
Effect of Natural Antibacterial Mouthwash on Taste, Salivary pH and Bacteria in High Caries Risk pt
Evaluate the effect of propolis extract mouthwash and pomegranate extract mouthwash on taste alteration, salivary pH and antibacterial activity against streptococcus mutans in high caries risk patients.
- Trial name
- NCT03623048
- Testing
- chlorhexidine, saline, Propolis extract
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries, Erosive Tooth Wear
New In Situ Model Design for Caries and Erosion
This study will test simultaneously and independently two novel in situ models, one for caries and one for erosive tooth wear (ETW), based on the simulation of these dental conditions on enamel specimens placed on 3D-printed…
- Trial name
- NCT07849270
- Testing
- 0 ppm fluoride toothpaste, 250 ppm fluoride toothpaste (dose-response control), 1150 ppm fluoride toothpaste
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Indiana University
Dental Caries
Occlusal ART Restorations in Primary Molars Using 3 Different GIC
The aim of this study is to evaluate the survival rate and the cost-effectiveness of occlusal-ART restorations using three GIC brands (Fuji IX, GC Europe; Maxxion R, FGM; Vitro Molar, DFL) in primary molars.
- Trial name
- NCT02377297
- Testing
- Restoration with Fuji IX, Restoration with Vitro Molar, Restoration with Maxxion R
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Caries Extending Into Dentin
Antibacterial Effect of Light-activated Calcium Silicate Versus Light-activated Calcium Hydroxide
This is a randomized clinical study. 48 subjects with a confirmed diagnosis of deep carious molars without pulpal lesions were randomized to one of two treatments: Patients treated with Light-cured calcium silicate (Theracal)…
- Trial name
- NCT03214770
- Testing
- TheraCal, light-cured calcium hydroxide
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Fissure Sealants
Comparative Evaluation of Glass Ionomer and Resin-Based Fissure Sealants on Newly Erupted Permanent First Molars: A 24-Month Randomized Clinical Trial
This clinical study aims to compare the clinical performance of two different fissure sealant materials-glass ionomer and resin-based-when applied to newly erupted permanent first molars in children.
- Conditions
- Dental Caries, Fissure Sealants, Permanent Molars, Child
- Trial name
- FISSURE24 (NCT07115290)
- Testing
- Glass ionomer-based fissure sealant, Resin-based fissure sealant
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Gulcin Bulut