Clinical trials: Tooth Caries
Caries,Dental, Crown of Tooth With Poor Contour
Clinical and Radiographical Evaluation of CAD-CAM Crowns With and Without Deep Margin Elevation
Deep margin elevation (DME) is a non-invasive restorative technique to relocate the deep cervical margin to a supragingival position using resin composite.
- Conditions
- Caries,Dental, Crown of Tooth With Poor Contour, Broken Teeth, Survival, Prosthesis
- Trial name
- NCT06114030
- Testing
- Deep margin elevation with composite resin and Lithium disilicate glass-ceramic crowns
- Where
- United Arab Emirates
- Volunteers
- 560 people
- Sponsor
- University of Sharjah
Early Childhood Caries
Atraumatic Restorative Treatment (ART) in Early Childhood Caries (ECC)
Considering the severity and high prevalence of ECC, as well as the importance of early intervention and approach, the Atraumatic Restorative Treatment program, because of its advantages, consists of an important treatment…
- Trial name
- ART-ECC (NCT03756025)
- Testing
- Atraumatic Restorative Treatment (ART)
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Hospital Nossa Senhora da Conceicao
Dental Pulp Cavity
Evaluation of Triple Antibiotic Paste Pulp Therapy Compared to Vitapex in Primary Molars.
The aim of the study was to compare the clinical and radiographic success of triple antibiotic paste (TAP) which includes (metronidazole, ciprofloxacin, and minocycline) and Vitapex (calcium hydroxide/iodoform paste) for root…
- Trial name
- NCT04547764
- Testing
- triple antibiotic paste (TAP), Vitapex (calcium hydroxide/iodoform paste)
- Where
- Saudi Arabia
- Volunteers
- 54 people
- Sponsor
- King Abdulaziz University
Dental Caries
Microbiological Evaluation and Clinical 24-month Follow-up of Adhesive Systems on Carious Dentin
The objectives were to evaluate the antibacterial effect of self-etching adhesives on carious dentin and the clinical results of restorations in a randomized controlled clinical trial.
- Trial name
- NCT05676671
- Testing
- Applications of self-etching adhesives and dental restorations
- Where
- Brazil
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Caries in Children, Dental Diseases
Information and Communication Technologies (ICTS) in Dentistry for SUS
At the time of the COVID-19 pandemic, thousands of children had their dental care interrupted or postponed, generating a pent-up demand for primary care.
- Trial name
- NCT04798599
- Testing
- Telemonitoring and teleorientation, Control Group - Waiting list
- Where
- Brazil
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Caries
Fluoride Release,Compressive Strength and Clinical Performance of a Bioactive Restorative Material in ART
The study will be two parallel group, triple blinded randomized controlled clinical trial that based on CONSORT (consolidated standards of reporting trials) guideline .The selected participants according to inclusion and…
- Trial name
- NCT03788616
- Testing
- Fuji IX EXTRA, ACTIVA KIDS bioactive restorative material
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Marina F Fahmy, MD
Dental Caries, Dental Caries of Root Surface
Silver Diamine Fluoride for Caries Prevention in Removable Partial Dentures Wearers
This study measures and compares the effect of silver diamine fluoride (SDF) on caries increment in removable partial denture wearers. Half of the participants will SDF and while the other half will receive placebo.
- Trial name
- NCT03185104
- Testing
- Silver Diamine Fluoride, Distilled Water
- Volunteers
- 196 people
- Sponsor
- The University of Hong Kong
Dental Caries
Clinical Performance of Bioactive Bulk-Fill in Class II Restorations
This prospective split-mouth clinical study aims to compare the clinical performance of a bioactive bulk-fill composite with a conventional microhybrid composite in Class II posterior restorations.
- Trial name
- NCT07547904
- Testing
- Activa BioACTIVE Bulk Flow, Filtek Z250
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Bezmialem Vakif University
Primary Teeth
Direct Resin Composite Restoration of Primary Anterior Teeth Using Custom 3D Printed Templates
Esthetic restoration of primary anterior teeth is challenging. Aim of the study: Evaluation of the 12-month clinical performance of direct resin composite restoration of carious vital primary anterior teeth using custom 3D…
- Trial name
- RCT (NCT06478004)
- Testing
- Direct composite restoration of carious primary anterior teeth using custom 3D printed templates, Direct composite restoration of carious primary anterior teeth using conventional strip crowns
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Minia University
Caries, Defective Tooth Restorations
Prospective, Split-mouth, Comparative Study to Compare Clinical Outcomes of Two Different Posterior Composite
The objective of this 2-year split mouth comparative study, a randomized controlled study, is to determine whether the simplified placement procedure of the ultra-rapid polymerizing Tetric PowerFlow/ Tetric PowerFill with a…
- Trial name
- NCT04708223
- Testing
- Direct restorative treatment with fast-curing composites (Tetric PowerFill/ Tetric PowerFlow), Direct restorative treatment with conventionally applied composites (Tetric EvoCeram Bulk Fill/ Tetric EvoFlow Bulk Fill)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Ivoclar Vivadent AG
Dental Caries in Children
SDF for the Management of Dental Caries in Children in Primary Dental Care: Protocol for a Feasibility Study
Dental caries remains a significant health problem in England, effecting 11% of 3-year-olds and 23% of 5-year- olds. Children with dental caries suffer pain, infection and poor oral health-related quality of life.
- Trial name
- NCT06092151
- Testing
- Silver diamine fluoride, Usual dental care
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Dental Caries
Impact of Atraumatic Restorative Treatment and Oral Health Promotion on Psychological and Salivary Aspects of Children
This study evaluated the impact of atraumatic restorative treatment associated with oral health educational strategy on dental anxiety, oral health-related quality of life and salivary biochemical and microbiological…
- Trial name
- NCT03100773
- Testing
- Oral health educational strategy, Atraumatic Restorative Treatment
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Dental Caries
Traditional vs. Minimally Invasive Decay Treatments in Primary Molars: An 18-month Split-mouth Randomized Study
The goal of this clinical trial is to compare the 18-month clinical success rates of three caries management approaches in primary molars of 60 healthy children aged 4-8 years attending the Department of Pediatric Dentistry at…
- Trial name
- MiCRO-PM (NCT07447583)
- Testing
- Hall Technique, Silver diamine Fluoride 38%, Compomer Restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Dental Caries, Tooth Demineralization
Effectiveness of Two Health Education Interventions in the Prevention of Caries and Gingivitis in Orthodontic Patients
Dental caries and gingivitis are classified by the World Health Organization (WHO) as an important public health problem due to their high prevalence and incidence worldwide despite the development of public policies to combat…
- Conditions
- Dental Caries, Tooth Demineralization, Gingivitis
- Trial name
- NCT05979805
- Testing
- Conventional Educational interventions, Motivational intervention
- Where
- Colombia
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Mutans Streptococci, Xerostomia
Xylitol Disk Use in Adults With Dry Mouth
The purpose of this study is to demonstrate whether decay causing bacteria are reduced when adhesive xylitol disks are used intraorally three times a day for two weeks in adults with dry mouth.
- Trial name
- NCT01823445
- Testing
- Xylitol disk
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Washington
Dental Caries, Dental Caries in Children
Technology-enabled Anticipatory Guidance and Peer Support in Empowering Parents to Prevent Early Childhood Caries
Early Childhood Caries (ECC) is a significant clinical and public health challenge that the world and the Singapore population are facing.
- Conditions
- Dental Caries, Dental Caries in Children, Diet Habit
- Trial name
- NCT06558955
- Testing
- Technology-enabled anticipatory guidance and peer support, Conventional health education
- Where
- Singapore
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Toothbrushing, Dental Plaque
BEhavioral EConomics for Oral Health iNnovation Pilot Trial
This Phase I randomized pilot trial will assess the efficacy of a fixed incentive payment program and drawing incentive payment program versus a control program to promote early childhood caries (ECC) preventive health behaviors…
- Conditions
- Toothbrushing, Dental Plaque, Parent-Child Relations, Oral Hygiene
- Trial name
- BEECON Pilot (NCT03862443)
- Testing
- Fixed Incentive, Drawing Incentive
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dental Caries
Composites and Urinary Bisphenol-A Study
The Composites and Urinary Bisphenol-A Study (CUBS) is a clinical study of dental composite for its effects on urinary bisphenol-A levels.
- Trial name
- CUBS (NCT01484132)
- Testing
- Restoration of dental caries with dental composite
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Carelon Research
Bacterial Infections, Dental Caries
Hydrogen Peroxide Fumigation in Dental Office Environment
The study's null hypothesis posits no significant difference in bacterial levels in the dental office environment before and after implementing hydrogen peroxide (H₂O₂) fumigation.
- Conditions
- Bacterial Infections, Dental Caries, Aerosol Disease
- Trial name
- NCT06100848
- Testing
- Microbiological analysis after Caries treatment, Microbiological analysis after Caries treatment and fumigation
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Dental Caries in Children
Pandemic-adapted Caries Care Multicentre Single-group Interventional Study
The current understanding of dental caries has not been completely transferred into the clinical practice to control caries lesion progression (severity / activity) and the individual risk of caries.
- Trial name
- NCT04666597
- Testing
- Modified CariesCare International management
- Where
- 21 sites in United States, Argentina and 11 more
- Volunteers
- 409 people, healthy volunteers welcome
- Sponsor
- Universidad El Bosque, Bogotá
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