Clinical trials: Tooth Decay
Dental Caries
A Clinical Study to Evaluate Experimental Children's Toothpastes in an In-Situ Caries Model
An in situ model will be used to evaluate and compare enamel remineralization of human enamel specimens after single use of experimental children's toothpastes.
- Trial name
- NCT01607411
- Testing
- Fluoride
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dental Restoration, Dental Caries
Resin Bulkfill Dual-Cured of Proximal Restoration. Clinical Trial
Objective: To evaluate the immediate clinical performance using FDI criteria in occlusal and proximal lesions restored with dual polymerization bulkfill composite resin.
- Trial name
- NCT05013853
- Testing
- Restoration teeth
- Where
- Chile
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Andres Bello
Tooth Decay, Cavities of Teeth
Plaque Removal Effectiveness of a Flossing Device Compared to the Conventional Flossing in Adults
Objective: To evaluate the effectiveness in plaque removal of the new device; Dental floss holders and compare the results to the conventional way of flossing.
- Conditions
- Tooth Decay, Cavities of Teeth, Gingivitis, Plaque
- Trial name
- NCT06318819
- Testing
- Dental Floss Holders
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maha A. Bahammam
Children in School
Caries Risk Assessment in Children and Adolescents in the Alpes Maritimes (France)
Identification of caries high risk subjects. Studying the relevance and the distribution of caries risk factors as defined by the HAS, and the part played by the zone of schooling (priority education area or not) Studying the…
- Trial name
- NCT01372436
- Where
- 2 sites in France
- Volunteers
- 678 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Dental Caries
Reliability of Fluorescent Camera and Caries Detection Dye Versus the Visual Tactile Method
1. Three dentinal carious lesions will be chosen in this study and will be in the same patient. 2. Using local anaesthesia and rubber dam, the operative field will disinfected with 1% hypochlorite, and the dentine lesions should…
- Trial name
- NCT03051594
- Testing
- fluorescent camera, caries detector dye, visual tactile assessment
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Clinical Evaluation of Direct and Indirect Composites
The most commonly used materials in the treatment of decayed teeth are amalgam and composite resins. Because amalgam cannot meet the aesthetic expectations of patients and the rapidly increasing belief that it is toxic, its use…
- Trial name
- NCT06667271
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Dental Caries
Preventive Effect of a Probiotic Tablet on Oral Health in Preschool Children
The aim of the prospective project is to investigate effect of daily probiotic supplements on dental caries development in preschool children living in a low socioeconomic immigrant area in souithern Sweden.
- Trial name
- NCT01720771
- Testing
- probiotic tablet, sugar pill
- Where
- Sweden
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dental Caries
Educational Intervention in Preventing Early Childhood Caries
Objective: The aim of this study is to assess the effectiveness of an oral health educative intervention in preventing early childhood caries (ECC).
- Trial name
- NCT01502566
- Testing
- Education Intervention
- Where
- Brazil
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Carious Lesion
Clinical Evaluation of SDF Combined With KI Versus SDF in Management of Class I Carious Lesions
To evaluate the clinical performance of High-Viscosity Glass Ionomer (EQUIA) versus Silver Diamine Fluoride combined with Potassium Iodide (Riva Star) and Sliver Diamine Fluoride (SDF) under High-Viscosity Glass Ionomer (EQUIA)…
- Trial name
- NCT05485272
- Testing
- Silver Diamine Fluoride combined with Potassium Iodide., Silver Diamine Fluoride., High-Viscosity Glass Ionomer.
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Radiographic Contrast To Differentiate Cavitated From Non-cavitated Tooth Decay
The proposed test is intended to enable dentists to differentiate between cavitated and non-cavitated tooth decay in the areas where teeth are in contact (interproximal surfaces).
- Trial name
- NCT02359279
- Testing
- Sodium iodide
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Creighton University
Dental Caries
Use of Radiographic Contrast to Detect Dental Caries
The proposed test is intended to enable dentists to differentiate between cavitated and non-cavitated tooth decay in the areas where teeth are in contact (interproximal surfaces).
- Trial name
- NCT01523509
- Testing
- Radiographic contrast agent. Sodium Iodide.
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Creighton University
Dental Caries, Dental Caries Class II
Clinical Performance of Novel Alkasite Restorative Material "Cention Forte" in Class II Restorations
Background \& Rationale: Self-adhesive materials eliminate the need for adhesive protocols, offering advantages for direct restorations. The bulk-fill technique simplifies application by allowing a single-layer restoration.
- Trial name
- NCT06833528
- Testing
- tooth restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries
Microbiological Evaluation and Clinical 24-month Follow-up of Adhesive Systems on Carious Dentin
The objectives were to evaluate the antibacterial effect of self-etching adhesives on carious dentin and the clinical results of restorations in a randomized controlled clinical trial.
- Trial name
- NCT05676671
- Testing
- Applications of self-etching adhesives and dental restorations
- Where
- Brazil
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Caries,Dental
Correlation Between Caries Experience in Primary Molars and First Permanent Molars
A cross- sectional observational study which will investigate whether data of past caries experience of the primary molars of 6-9 years old children can serve as an indicator for caries development in first permanent molars.as…
- Trial name
- NCT03671200
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Clinical Evaluation of Zirconia Crowns and Anterior Strip Crowns
The hypothesis to be investigated is that no difference will be found upon comparing resin composite strip crowns and NuSmile zirconia crowns (NuSmile ZR) esthetic primary anterior in restoring anterior primary teeth.
- Trial name
- NCT03184012
- Testing
- NuSmile Zirconia crowns by NuSmile company, Composite resin strip crowns by 3M company
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Dental Caries
Effect of a Sugar-Free Chewing Gum Containing Magnolia Bark Extract on Caries Lesions in Healthy Adult Volunteers
The effect of chewing gums containing MBE and xylitol on different variables related to caries and gingivitis in a sample of adult volunteers with a high risk for caries will be evaluated.
- Trial name
- NCT02310308
- Testing
- Chewing gum administration
- Where
- 2 sites in Italy
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Dental Caries, Dental Fluorosis
Anticaries Potential and Fluorosis Risk From Different Fluoride Toothpastes
Fluoride toothpaste has been associated not only with declining dental caries prevalence but also with an increase in dental fluorosis.
- Trial name
- NCT01589991
- Testing
- Toothpaste
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Dental Caries
Comparative Evaluation of Hydrophilic and Hydrophobic Sealants in Partially Erupted First Molars
This randomized controlled clinical trial aims to evaluate and compare the retention, caries prevention, microleakage, and fluoride release of three types of pit and fissure sealants-hydrophilic, nanofilled hydrophobic, and…
- Trial name
- NCT07052526
- Testing
- Prevention, Prevention of caries, Prevention therapy
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Caries, Dental Plaque Accumulation
Miswak (Salvadora Persica) Versus a Toothbrush in Plaque Removal
The study investigates the effectiveness of a 45°-cut miswak for plaque removal compared to a toothbrush in children and assesses their preferences for these tools.
- Trial name
- NCT07409610
- Testing
- Miswak, Toothbrush
- Where
- Saudi Arabia
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Dental Caries
Stopping Cavities Study: Diammine Silver Fluoride
This study is being conducted to test whether the use of diammine silver fluoride (also called silver diamine fluoride) hardens the cavity sufficiently so that it arrests.
- Trial name
- NCT02536040
- Testing
- 38% diammine silver fluoride, Water
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Advantage Dental Services, LLC