Clinical trials: Tooth Decay
Dental Caries in Children
The Impact of Anticipatory Guidance on Early Childhood Caries: a Quasi-experimental Study
This study aimed to compare the impact of anticipatory guidance on the caries incidence of 2-3-year-old preschool children and their 4-6-year-old siblings, as well as on their mothers' oral health literacy, as compared to the…
- Trial name
- NCT03478748
- Testing
- Dental health education
- Where
- Malaysia
- Volunteers
- 478 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Dental Caries on Pit and Fissure Surface
Using ICDAS II and KaVo DIAGNOdent Pen Detecting Tooth Pit and Fissure Level Incipent Caries Progression
The study was to monitor effectiveness of glass ionomer sealant and resin-based sealant in ICDAS, and to evaluat the correlation between ICDAS and DIAGNOdent over 24 months.
- Trial name
- NCT03077035
- Testing
- glass ionomer sealants, resin-based sealant
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sheng-Chao Wang
Parenting, Cavity, Dental
Brief Interventions to Improve Behavior Outcomes and Prevent Cavities
The investigators will study brief educational interventions designed to address childhood behavior problems and prevent cavities.
- Conditions
- Parenting, Cavity, Dental, Child Behavior
- Trial name
- NCT06588725
- Testing
- Play Nicely, Cavity Prevention Handout
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Cardiac Disease, Dental Caries
Saliva Profiles in Children With Congenital Heart Disease
The purpose of this study was to evaluate whether there are relationships between the salivary oxidative stress status of children with CHD directly dental caries including gender, age, salivary flow rate, salivary pH, salivary…
- Trial name
- NCT03457974
- Testing
- saliva
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Decay, Dental
Effect of Natural Antibacterial Mouthwash on Taste, Salivary pH and Bacteria in High Caries Risk pt
Evaluate the effect of propolis extract mouthwash and pomegranate extract mouthwash on taste alteration, salivary pH and antibacterial activity against streptococcus mutans in high caries risk patients.
- Trial name
- NCT03623048
- Testing
- chlorhexidine, saline, Propolis extract
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Occlusal ART Restorations in Primary Molars Using 3 Different GIC
The aim of this study is to evaluate the survival rate and the cost-effectiveness of occlusal-ART restorations using three GIC brands (Fuji IX, GC Europe; Maxxion R, FGM; Vitro Molar, DFL) in primary molars.
- Trial name
- NCT02377297
- Testing
- Restoration with Fuji IX, Restoration with Vitro Molar, Restoration with Maxxion R
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Caries, Fissure Sealants
Comparative Evaluation of Glass Ionomer and Resin-Based Fissure Sealants on Newly Erupted Permanent First Molars: A 24-Month Randomized Clinical Trial
This clinical study aims to compare the clinical performance of two different fissure sealant materials-glass ionomer and resin-based-when applied to newly erupted permanent first molars in children.
- Conditions
- Dental Caries, Fissure Sealants, Permanent Molars, Child
- Trial name
- FISSURE24 (NCT07115290)
- Testing
- Glass ionomer-based fissure sealant, Resin-based fissure sealant
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Gulcin Bulut
Dental Caries
Caries Prevention Effect of S-PRG Filler Incorporated in Denture Base Resins on Edentulous Elderly People
The purpose of this study is to determine whether a novel material of S-PRG fillers containing in a daily-used resin denture base and their capability of fluoride release and recharge to elevate the salivary fluoride level and…
- Trial name
- NCT02460562
- Testing
- S-PRG filler, PMMA resin
- Where
- 3 sites in Thailand
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kritirat Kiatsirirote
Preschool Children, Dental Caries in Primary Teeth
A Comparison of Teledentistry vs Clinical Examination for Treatment Needs Assesment
Dental caries is one of the most common chronic diseases in children and may require complex dental treatment, especially in preschool-aged children.
- Trial name
- NCT07625982
- Testing
- Tele- dentistry intraoral exam
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Caries,Dental, Dental Caries
The Impact of Sage Extract on GTS B and D Gene Expression in S. Mutans
Glucosyltransferases (Gtfs) play a crucial role in the pathogenesis of dental caries caused by Streptococcus mutans. Gtfs is recognized as an attractive target for effective therapeutic interventions aimed at inhibiting…
- Conditions
- Caries,Dental, Dental Caries, Dental Diseases
- Trial name
- NCT06703554
- Testing
- Sage Oil Mouthwash, Chlorohexidine Mouthwash
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Diabetes Mellitus, Type 2, Dental Caries
Are Diabetics Type 2 More Prone to Dental Caries?
Background: Diabetes mellitus (DM) is well known for long-term complications to general and oral health. Periodontal disease has a bidirectional association with the development of type 2 diabetes (T2DM) (Mealey, 2006; Taylor…
- Trial name
- NCT04883086
- Where
- United Kingdom
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Dental Plaque, Dental Caries
Development of a Novel Anti-caries Chewing Gum
This research study is designed to evaluate the chewing gum's ability to modulate the oral microbiome in human participants, in addition to its safety.
- Conditions
- Dental Plaque, Dental Caries, Periodontal Disease
- Trial name
- NCT05946473
- Testing
- Gum base containing xylitol and essencial oils, Gum base with no additives
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Toronto