Clinical trials: Tooth Development Disorder
Hypersensitive, Molar Incisor Hypomineralization
Effect of Glass-Ionomer Sealing Technique on Hypersensitive Teeth With Molar Incisor Hypomineralisation
This single armed cohort study is aimed to assess the acceptance, durability and efficiency of glass-Ionomer sealing technique on hypersensitive MIH molars (TNI-3 \& 4a/b/c) clinically shortly (15 minutes) after the application…
- Conditions
- Hypersensitive, Molar Incisor Hypomineralization, Pit and Fissure Sealants
- Trial name
- MIH_GIC (NCT05945381)
- Testing
- GIC on MIH
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Molar Incisor Hypomineralization
Remineralization of Molar Incisor Hypomineralization (MIH) With a Hydroxyapatite Toothpaste
This study tests the remineralization of donor teeth (donorMIH) in situ in participants using 10% hydroxyapatite (HAP) toothpaste and sodium fluoride toothpaste.
- Trial name
- NCT05485662
- Testing
- Hydroxyapatite toothpaste, Sodium Fluoride Toothpaste
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Molar Incisor Hypomineralization, Fissure Sealant
Pre-etched Bioactive Versus Resin- Based Fissure Sealant for Permanent Molars Affected With Molar Incisor Hypomineralization (MIH).
This study aims to evaluate and compare the clinical performance of pre-etched bioactive fissure sealants to conventional RBFS in permanent molars affected by MIH in terms of retention, marginal integrity, caries prevention…
- Trial name
- NCT07504614
- Testing
- Pre-etched Bioactive Sealant, Conventional Resin-based Sealant
- Where
- Jordan
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Caries, Dental, Fluorosis, Dental
Dental Fluorosis Risk by the Use of Acidulated Fluoride Dentifrice
This research aimed to evaluate the risk of dental fluorosis by using an experimental fluoridated acidulated dentifrice compared to conventional dentifrices in two-to-four-year-old children residing in a non fluoridated area by…
- Trial name
- NCT03761485
- Testing
- Use of Dentifrice Fluoride
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Molar Incisor Hypomineralization
Comparing CAD/CAM vs Composite for Carious Hypomineralized Molars Evaluating Clinical Outcomes of Both Treatments.
Molar Incisor Hypomineralization (MIH) is enamel hypomineralization defined as qualitative defects caused by disruptions in either the calcification or maturation phases of amelogenesis affecting one or more first permanent…
- Trial name
- NCT07049016
- Testing
- restoring the MIH affected young permanent molars using Direct nanohybrid flowable composite, restoring the MIH affected young permanent molars using IPS e.max CAD
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Molar Incisor Hypomineralization, Dental Caries
Prevalence of MIH in Young Adults At Cairo University Dental Hospital and Its Link to Dental Cavities: a Cross-Sectional Study
We are conducting a study to understand how often MIH (Molar Incisor Hypomineralization) occurs and whether it is linked to a higher chance of dental cavities (caries).
- Trial name
- NCT06701552
- Where
- Egypt
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Enamel Hypomineralization
Clinical Success of Stainless Steel Crowns Applied Using Different Cements
The main question of the study was to evaluate the one-year clinical success of SSc bonded with two different cement types in MIH teeth with excessive material loss.
- Trial name
- NCT06318520
- Testing
- Use of Calcium silicate based resin cement and resin modified glass ionomer cement
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Dental Caries
The Relation Between Pregnancy,Birth Outcome, Feeding , Oral Hygiene Habits and Early Childhood Caries Development.
200 children between ages 36 to 48 months will be invited for a regular dental examination Parameters to be investigated 1. Pregnancy history 2. Birth outcome 3. Child's general health 4. Feeding habits 5. Oral hygiene habits 6.
- Trial name
- NCT00334087
- Testing
- feeding habits
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Premature Loss of Primary Molars, Space Maintenance
Space Changes After Premature Loss of Lower First Primary Molars in Children Using Digital Scanning
This prospective split-mouth clinical study aims to evaluate space changes in the mandibular dental arch following premature extraction of the lower first primary molar in children aged 3 to 5.5 years.
- Conditions
- Premature Loss of Primary Molars, Space Maintenance, Dental Arch Development, Pediatric Tooth Extraction
- Trial name
- NCT06965777
- Where
- Egypt
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hypomineralization of Enamel, Dental Fear
Analysis of Treatment Outcomes in Patients Affected by Molar-Incisor Hypomineralization (MIH)
The aim is to long-term evaluate extraction or restoration therapy, of first permanent molars with extensive treatment needs as a result of severe MIH in a national multicenter study concerning dental fear and anxiety, oral…
- Conditions
- Hypomineralization of Enamel, Dental Fear, Quality of Life
- Trial name
- GuREx-MIH (NCT06228989)
- Testing
- Restorative therapy, Extraction therapy
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Göteborg University
White Spot Lesion, Enamel Hypomineralization
Evaluation of CPP-ACP Prophylactic Effect on Enamel Surface During Orthodontic Treatment
This study is aiming in preventing the formation of WSL associated with orthodontic treatment which occurs to more than 50% of orthodontically treated patients through applying CPP-ACP on the enamel surface once every 2 weeks for…
- Trial name
- NCT03187548
- Testing
- Casein Phosphopeptide-Amorphous Calcium Phosphate Dental Paste
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dentin Sensitivity, Molar Incisor Hypomineralization
MIH and Hypersensitivity in Children
The aim of this study was to evaluate the efficacy of the association of casein phosphopeptide plus amorphous calcium phosphate (CPP-ACPF) mousse and photo-bio-modulation therapy (PMBT) (diode laser, RAFFAELLO 980 BIO - Dental…
- Trial name
- NCT05705037
- Testing
- CPP-ACPF, PBMT, CPP-ACPF+PBMT
- Where
- Italy
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Brescia
Molar-Incisor Hypomineralization (MIH), Masticatory Performance
Evaluation of Occlusal Force and Masticatory Function in Children With Molar-Incisor Hypomineralization
This study aims to evaluate right-left chewing balance and masticatory function in children with Molar-Incisor Hypomineralization (MIH) before and after restorative treatment.
- Conditions
- Molar-Incisor Hypomineralization (MIH), Masticatory Performance, Occlusal Analysis, Chewing Function
- Trial name
- NCT07589179
- Testing
- Glass Hybrid Restorative Treatment
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Marmara University
Molar Incisor Hypomineralisation
The Effect of Salvadora Persica (Miswak) Compared to Fluoridated Toothpaste on Children's Teeth Diagnosed With Molar-Incisor Hypomineralization (MIH): A Randomized Clinical Trial
Molar-Incisor Hypo mineralization (MIH) was first described in 2001 as a developmental enamel defect . It is a condition in which the enamel of at least one first primary molar is affected with a qualitative defect causing…
- Trial name
- NCT07355465
- Testing
- Salvadora persica (miswak), Fluoridated Toothpaste
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Molar Incisor Hypomineralisation, Irreversible Pulpitis
Pain Assessment Governing Partial or Full Pulpotomy of Immature Molars With Irreversible Pulpitis in Molar Incisor Hypomineralization
This randomized controlled clinical trial aims to evaluate and compare pain levels associated with partial pulpotomy (PP) and full pulpotomy (FP) in immature permanent first molars diagnosed with irreversible pulpitis.
- Conditions
- Molar Incisor Hypomineralisation, Irreversible Pulpitis, Immature Molars
- Trial name
- NCT07850986
- Testing
- pulpotomy for MIH affected immature PFMs, partial pulpotomy for MIH affected immature PFMs, pulpotomy for non-MIH affected immature PFMs
- Where
- Egypt
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Alaa Khafagy
Dentin Sensitivity, Molar Incisor Hypomineralization
Control of Pain Due to Dentin Hypersensitivity in Individuals With Molar-incisor Hypomineralization
Background: Dentin hypersensitivity (DH) is defined as high sensitivity of the vital dentin when exposed to thermal, chemical or tactile stimuli.
- Trial name
- NCT04407702
- Testing
- Hygiene Instructions, Sealant application, Low-level Laser
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Dental Caries, Dental Fluorosis
Fluoride Bioavailability After Ingestion of Water or Foods Prepared With Fluoridated Water
The importance of fluoridated water to control caries is well recognized. Although the mode of action of fluoridated water is known (related to a slight increase in fluoride concentration in saliva/dental biofilm in individuals…
- Trial name
- NCT01978041
- Testing
- Meal prepared with non fluoridated water, Meal prepared with fluoridated water, Non fluoridated water
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Tooth Extraction, Periapical Infections
Cortical Lamina for Alveolar Ridge Preservation
This randomized controlled clinical trial aims to evaluate the efficacy of placing a cortical lamina between the elevated flap and buccal bone plate following tooth extraction for preserving alveolar ridge dimensions.
- Conditions
- Tooth Extraction, Periapical Infections, Tooth Fracture, Periodontal Disease, AVDC Stage 4
- Trial name
- Lamina (NCT07231874)
- Testing
- Cortical Lamina Technique, Natural Healing (Control)
- Where
- Cuba
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- ARDEC Academy
Tooth Extraction, Tooth Extraction Site Healing
Assessment of the Impact of Neocement Inject P® (Beta-Tricalcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction
The goal of this randomized clinical trial is to assess whether β-TCP (Beta-Tricalcium Phosphate) improves alveolar ridge preservation (ARP) in patients who need tooth extraction.
- Conditions
- Tooth Extraction, Tooth Extraction Site Healing, Alveolar Bone Grafting, Alveolar Bone Loss
- Trial name
- BTCPARPBV (NCT07638319)
- Testing
- Neocement Inject P® (Beta-Tricalcium Phosphate)
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Enamel Hypomineralization, Dental
Esthetic Impact of Different Minimally Invasive Approaches on Hypomineralized Permanent Anterior Teeth
The aim of the study is to determine the effectiveness of minimally invasive treatments in reducing the visible enamel opacities on permanent anterior teeth in children aged from seven to twelve years with hypomineralized…
- Trial name
- NCT07906236
- Testing
- ICON® resin infiltration, Opalustre® enamel microabrasion, Antivet® enamel micro-abrasion
- Where
- Egypt
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Shaimaa Abdelrahman