Clinical trials: Tooth Disease
Dentin Sensitivity
A Clinical Study to Determine the Safety and Effectiveness of Dentinal Hypersensitivity Treatment With Two Different Toothbrushes
This study will determine the effects toothbrush type (power or manual) has on the safety and effectiveness of professional dentinal hypersensitivity treatment with a marketed oxalate-containing solution.
- Trial name
- NCT02513212
- Testing
- Potassium Oxalate, Stannous fluoride paste, Manual toothbrush
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Missing Teeth
A Proof of Concept for All-ceramic Zirconia Resin Bonded Bridges for Canine, Premolar and Short Span Posterior Teeth
Trial Design - Objectives and Purpose The aim of this study is to perform a proof of concept for the successful retention and outcome measures of zirconia RBBs for the replacement of missing canine or posterior teeth (6-8mm span)…
- Trial name
- NCT02793037
- Testing
- Zirconia resin bonded bridge
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Jaw, Edentulous, Partially
The Effect of Immediate Implant Placement and Provisionalization in the Esthetic Zone
The purpose of this study is to compare two different techniques of placing dental implants: 1) removing the tooth and placing the implant immediately and 2) removing the tooth and placing both the implant and a temporary crown…
- Trial name
- 3i (NCT02021331)
- Testing
- immediate implant placement without provisionalization, immediate implant placement with immediate provisionalization
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Dental Plaque
Dental Plaque Prevention Efficacy of a Stannous Fluoride Toothpaste
This randomized, stratified, double-blind, two-cell parallel clinical study evaluated the dental plaque prevention efficacy of a stannous fluoride toothpaste compared to a sodium fluoride control toothpaste following a…
- Trial name
- NCT07419737
- Testing
- Stannous Fluoride Toothpaste (SnF), Sodium Fluoride Dentifrice
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Dental Plaque, Dental Caries
Family-based Counseling Models for Young Children
The purpose of this study is to compare the effects of two new family-based oral health promotion programs with the routine program in use earlier in Vantaa public dental service.
- Conditions
- Dental Plaque, Dental Caries, Behaviorial Habits
- Trial name
- NCT01854502
- Testing
- Oral hygiene and fluoride use, Diet and use of xylitol
- Where
- Finland
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- University of Turku
Tooth Erosion
Investigate a Varnish to Protect From Erosive Toothwear
This in-situ study will investigate on extracted teeth the protection of a re-formulated varnish containing fluoride in the same concentration as an existing approved varnish used to treat caries and erosion.
- Trial name
- NCT06136754
- Testing
- Varnishes, Fluoride
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Periodontal Diseases, Dental Plaque
Marginal Biofilm Distribution and Periodontal Response to Supragingival and Juxtagingival Aligner Designs
This prospective, longitudinal, within-person (split-mouth) clinical study evaluates the influence of two clear aligner trimming-line designs on marginal soft-tissue biofilm distribution and periodontal tissue response over a…
- Conditions
- Periodontal Diseases, Dental Plaque, Gingivitis
- Trial name
- BIOFILM-ALIGN (NCT07642037)
- Testing
- Supragingival aligner trimming-line, Juxtagingival festooned aligner trimming-line
- Where
- Romania
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures
Endodontically Treated Teeth
Bite Force and Occlusal Force Distribution Following Root Canal Treatment.
Understanding the changes in bite force and occlusal force distribution in ETT is clinically important, as it can directly influence tooth prognosis, guide restorative treatment planning, and impact the long-term survival of the…
- Trial name
- B-FORCE RCT (NCT07626372)
- Where
- Thailand
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Dental Implant Failed, Teeth Absent
Gelatin Sponge VS PTFE Membrane for Socket Sealing After Immediate Implant Placement
Digital panoramas will be made to assess the implant sites. The included patients are assigned to their respective groups randomly.
- Conditions
- Dental Implant Failed, Teeth Absent, Soft Tissue Injuries
- Trial name
- NCT05982353
- Testing
- PTFE application, Gelatin sponge
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Endodontic Disease, Regenerative Endodontics
Evaluation of Different Scaffolds in Regenerative Endodontic Treatment
The aim of this study is to evaluate and compare the regenerative potentials of Injectable Platelet-Rich Fibrin (I-PRF), Platelet-Rich Fibrin (PRF), and Blood Clot (BC) as different scaffolds regarding: Radiographic outcomes…
- Trial name
- NCT06945965
- Testing
- Injectable platelet-rich fibrin (i-PRF) scaffold, platelet-rich fibrin (PRF)scaffold, blood clot (BC) scaffold
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Dental Caries
Comparison of the Effect of Fluoride Remineralizer Gel and Foam
Compare the remineralizing effect of acidulated fluoride gel Flugel (1.23% FFA, DFL) and acidulated Fluoride Foam Flúor Care (1.23% FFA, FGM) in maxillary anterior permanent teeth of 58 children aged 7 to 12 years of age.
- Trial name
- NCT02490592
- Testing
- Fluoride Foam, Fluoride gel
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University Center of João Pessoa
Wound Healing and Prevention, Oral Inflammation
Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva
The intervention in this study is to determine whether multiple applications of photobiostimulation with Nd-YAG laser improve wound healing following tooth extraction and alveolar ridge preservation.
- Conditions
- Wound Healing and Prevention, Oral Inflammation, Photobiomodulation, Post-operative Pain Management
- Trial name
- NCT07095556
- Testing
- Low-level laser therapy
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Dental Caries
Research on the Characteristics and Application of Lactobacillus Rhamnosus X253 as Oral Probiotics
The aim of the study is to study the application of Lactobacillus rhamnosus X253 as oral probiotics by the way of a randomised, double blinded, parallel, placebo-controlled clinical trial, and to eto detect the changes in oral…
- Trial name
- NCT05123651
- Testing
- Lactobacillus rhamnosus X253
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Junlebao Dairy Group Co., Ltd.
Clear Aligner Appliance
Evaluation of the Efficacy of Injectable Platelet-rich Plasma in Tooth Movement Acceleration With Clear Aligner
Aim of the study is evaluation of the efficacy of injectable platelet-rich plasma in orthodontic tooth movement acceleration with clear aligner
- Trial name
- NCT07103551
- Testing
- Platelet-rich plasma
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Pulpitis, Pulp Exposure, Dental
Pulpotomy in Carious Permanent Mature Teeth: Pulp Survival and Risk Factors
This Trial evaluated the extent of pulp survival following pulpotomy in the permanent tooth pulp exposed by caries and identify potential risk factors for pulpal complications.
- Conditions
- Pulpitis, Pulp Exposure, Dental, Pulp and Periapical Tissue Disease
- Trial name
- NCT03490422
- Testing
- Pulpotomy
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- National University Health System, Singapore
Caries, Tooth Decay
Improving Oral Health With Serious Games
This study investigated if computer games can be effective at changing the way children take care of their teeth. We a museum exhibit with 3D virtual reality games called "Attack of the S.
- Conditions
- Caries, Tooth Decay, Cavities, Gingivitis
- Trial name
- AOTSM (NCT02027597)
- Testing
- Attack of the S. Mutans, Follow-up, SnowWorld
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- University of Washington
Malocclusion, Compliance, Patient
The Effectiveness of Electronic Reminders in Improving Elastic Compliance in Orthodontic Patients
Fixed orthodontic appliances in combination with intraoral elastics are a common and effective method use in the orthodontic correction of malocclusions. However, their success is largely dependent on the patient's compliance.
- Trial name
- NCT03144323
- Testing
- Reminders
- Where
- 2 sites in United Kingdom
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Dental Pain and Sensation Disorder, Pain, Postoperative
Efficacy of Preoperative Administration of Gabapentin in 3rd Molar Dental Extraction.
This study is a double-blind, randomized, prospective, placebo-controlled single-center clinical research study in which 600 mg of gabapentin or placebo will be administered 2 hours preoperatively to 49 patients each undergoing…
- Trial name
- NCT04860141
- Testing
- Gabapentin 600mg
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Carious Teeth, Adaptation
Marginal Evaluation of Zirconia Reinforced Lithium Disilicate Partial Coverage Restoration of Egyptian Posterior Teeth.
Objective: To evaluate the marginal adaptation of the zirconia reinforced lithium disilicate (VITA AMBRIA) glass ceramic Inlay/Onlay compared with lithium disilicate(IPS emax Press) glass ceramic Inlay/Onlay in decayed posterior…
- Trial name
- NCT05281861
- Testing
- Zirconia reinforced Lithium disilicate (Vita Ambria) ceramic onlay restoration, Lithium disilicate (IPS e-max press) ceramic onlay restoration
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Attention Deficit Disorder With Hyperactivity, Dental Caries
Oral Status and Prevalence of Dental Trauma in Children Treated With Ritalin Due to Attention-Deficit Hyperactivity Disorder (ADHD)
To evaluate the dental status of children using ritalin and suffering from ADHA in comparison to healthy children.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Dental Caries, Dental Occlusion, Traumatic
- Trial name
- NCT00328224
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
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