Clinical trials: Tooth Diseases
Tooth Discoloration, Tooth Fractures
One Year Clinical Evaluation of IPS Empress CAD Versus Polished Celtra Duo Ceramic Laminate Veneers
When restoring teeth with IPS Empress laminate veneers, fracture of restorations may occur. So, material with higher mechanical properties is required.
- Conditions
- Tooth Discoloration, Tooth Fractures, Diastema
- Trial name
- NCT03136276
- Testing
- IPS Empress CAD, polished Celtra Duo
- Volunteers
- 36 people
- Sponsor
- Cairo University
Periodontal Diseases, Tooth Abrasion
The Effect of Bristle Brush, Rubber Cup, and Air Polishing on Tooth Surface Roughness of Scaled Teeth
This study investigates the effects of three polishing methods using a bristle brush, rubber cup, and air polishing on the surface roughness of scaled human teeth.
- Conditions
- Periodontal Diseases, Tooth Abrasion, Dental Plaque
- Trial name
- NCT06857474
- Testing
- Bristle Brush Polishing, Rubber Cup Polishing, Air Polishing
- Where
- Pakistan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Plaque, Dental, Gingivitis
Evaluation of Toothbrush Bristles in Plaque Reduction
The purpose of this cross-over clinical research is to evaluate the cleaning efficacy of toothbrushes tufted with two types of tapered bristles and end rounded bristles in removal of interdental plaque with clinical measurement…
- Trial name
- NCT04681885
- Testing
- Tapered bristles A, Tapered bristles B, End rounded bristles
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sunstar Americas
Sclerotic Dentine, Non Carious Cervical Lesion
Clinical Performance of Different Adhesive Strategies With a Universal System in Sclerosed Dentin in NCCL: A Double-blind Randomized Clinical Trial.
The aim of this randomized, prospective, parallel, double-blind clinical trial will be to evaluate the clinical performance of restorations performed in non-carious cervical lesions (NCCL) using a soft ph universal adhesive…
- Trial name
- NCT05211908
- Testing
- Composite resin restoration with Self Etch adhesive protocol and absence of sclerotic dentin, Composite resin restoration with Seletive enamel etch adhesive protocol and absence of sclerotic dentin, Composite resin restoration with Self Etch adhesive protocol and presence of sclerotic dentin
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Diabetes Mellitus, Type 2, Delayed Wound Healing
Hyaluronic Acid Treatment of the Post-extraction Tooth Socket Healing in Subjects With Diabetes Mellitus Type 2
The aim of the present split-mouth study was to investigate the effect of Hyaluronic Acid (HA) in improving the post-extraction tooth socket healing in subjects with diabetes mellitus type 2.
- Conditions
- Diabetes Mellitus, Type 2, Delayed Wound Healing, Tooth Extraction Status Nos
- Trial name
- NCT05896319
- Testing
- Hyaluronic acid gel
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- University of Turin, Italy
Follicle Cyst, Teeth, Impacted
Histopathologic Changes in Dental Follicle Associated With Radiographically Normal Impacted Lower Third Molars
This study aimed to evaluate the incidence of histopathologic changes in dental follicles associated with radiographically normal impacted lower third molar and to determine the relationship between cystic changes in follicle…
- Conditions
- Follicle Cyst, Teeth, Impacted, Pathology
- Trial name
- NCT04708119
- Testing
- The follicular tissues were also excised after tooth extraction.
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Malocclusion, Angle Class I
Arch Dimension and Inclination of the Upper and Lower Incisors Changes
It is intended to evaluate changes in arch dimensions and incisor inclination as well as changes in the WALA Ridge in no extraction patients treated with interactive self-ligating brackets (Empower®) and passive (Carriere SLX®)…
- Trial name
- NCT03129919
- Testing
- Carriere SLX® (Passive self-ligating braces), Empower® (Interactive self-ligating braces)
- Volunteers
- 60 people
- Sponsor
- Fundación Universitaria CIEO
Malocclusion, Angle Class II, Division 1
Low-Level Laser Therapy and Flapless Corticopuncture Effect on Accelerating Six Maxillary Anterior Teeth Retraction
The long time needed for orthodontic treatment is considered one of the biggest obstacles that make patients refuse to undergo orthodontic treatment.
- Trial name
- NCT03999307
- Testing
- Low-Level Laser Therapy (LLLT), Flapless Corticopunture, Control
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Tooth Decay
Clinical and Radiographical Evaluation of Two Types of Composite Materialsstrip Crown in Primary Molars
Alterations in oral health of children interfere with their quality of life. Dental caries is the most common public health problem of children .
- Trial name
- NCT05908136
- Testing
- restorative materials
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Al-Azhar University
Partial Edentulism, Tooth Disease
Assessment of the Effect of a Novel Surface Roughness Treatment on Dental Implants on Integration Success
A study where dental implants with different roughened surfaces will be evaluated for the ability to resist countertorque forces.
- Trial name
- Luna (NCT01529801)
- Testing
- Osseotite Certain Tapered Group A, Osseotite Certain Tapered Group B, Osseotite Certain Tapered Group C
- Where
- Chile
- Volunteers
- 80 people
- Sponsor
- ZimVie
Cervical Caries
Nobio Antimicrobial Particles Effect in a Split Mouth Model
The study purpose is to evaluate the antimicrobial effect of Nobio particles incorporated within Novidia Dental Bonding and Flowable Composite versus standard of care within a split mouth model.The study population will include…
- Trial name
- NCT03501784
- Testing
- Nobio particles incorporated within Novidia Dental Bonding, Filtek bond and flow composite
- Where
- Israel
- Volunteers
- 35 people
- Sponsor
- Nobio Ltd.
Periodontal Diseases, Dental Caries
Oral Health and Risk Factors for Oral Disease
Oral health has improved considerably in recent decades in Sweden, as well as in other countries. However, despite great improvements with regard to periodontal disease and dental caries in recent decades, global problems still…
- Conditions
- Periodontal Diseases, Dental Caries, Quality of Life
- Trial name
- NCT04081025
- Testing
- EpiWux
- Where
- Sweden
- Volunteers
- 2,500 people
- Sponsor
- Dalarna County Council, Sweden
Jaw, Edentulous, Partially
Comparison Between Cobalt-chromium Partial Dentures and Thermoplastic Partial Dentures
The cobalt-chromium (CoCr) partial denture has been made for a long period. It respects biomechanical principles, providing harmony between mechanical and biological activities.
- Trial name
- Flex (NCT01816425)
- Testing
- Thermoplastic partial denture, CoCr partial denture
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Tooth Sensitivity
Efficacy of Azadirachta Indica Based Herbal Mouthwash in Treating the Tooth Hypersensitivity
Type of study: Single-blinded clinical trial to evaluate the effectiveness of Azadirachta indica based Herbal mouthwash to treat the tooth sensitivity in patients.
- Trial name
- NCT06288776
- Testing
- Herbal based mouthwash
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Dental Caries
Evaluation of Antimicrobial Photodynamic Therapy as an Adjunct Treatment of Deep Carious Lesions in Children
This project aims to evaluate the effect of antimicrobial photodynamic therapy (aPDT) in deep carious lesions. This study was approved by the Research Ethics Committee and was conducted on 53 patients between 3 and 12 years.
- Trial name
- NCT02908789
- Testing
- Antimicrobial photodynamic therapy (aPDT), Without Antimicrobial phothodynamic therapy
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Pulp Disease, Dental
Clinical and Radiographic Assessment of Partial and Complete Pulpotomy in Primary Molars Using MTA
that's comparison between partial and complete pulpotomy techniques in primary teeth
- Trial name
- NCT04650113
- Testing
- MTA material
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Cairo University
Malformed Tooth
Clinical Evaluation of CAD/CAM vs. Conventional Veneer Restorations
The aim of the study is to clinically evaluate tooth-supported veneer restorations fabricated using the CAD/CAM process in comparison to conventionally manufactured pressed veneers on anterior teeth and to assess their long-term…
- Trial name
- NCT06969911
- Testing
- Laminate veneer CAD/CAM, Laminate Veneer Convetional
- Volunteers
- 40 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Pulpitis
The Use of Platelet-Rich Fibrin in Partial Pulpotomy Procedure
The aim of this study is to evaluate the clinical and histological pulp responses when MTA and a combined of MTA/PRF is used as pulp-capping agents after partial pulpotomy.
- Trial name
- NCT04331964
- Testing
- partial pulpotomy
- Where
- Syria
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Damascus University
Intraoperative Arterial Hypotension
Association of Intraoperative Blood Pressure Excursions Below Cerebral Autoregulatory Boundaries With Organ Injury Following Major Noncardiac Surgery
The aim of study is to investigate the clinical relevance of blood pressure (BP) excursions below cerebral autoregulatory boundaries in major noncardiac surgery.
- Trial name
- AR-NONCARDIAC (NCT05336864)
- Testing
- Non-invasive cerebral oximetry monitoring, additional perioperative blood sampling, clinical & telephone assessments
- Where
- 3 sites in Switzerland
- Volunteers
- 650 people
- Sponsor
- University Hospital, Basel, Switzerland
Jaw, Edentulous, Partially, Jaw, Edentulous
Immediate Loading of Implants in the Partially or Completely Edentulous Jaw
The investigators aim to evaluate the biological and mechanical short- and long-term outcome of IL in partially or completely edentulous patients.
- Trial name
- IMLOAD (NCT02661412)
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- AZ Sint-Jan AV