Clinical trials: Tooth Extraction, open to volunteers
Tooth Extraction, Dental Anxiety
Comparison of Needle-Free Injection and Conventional Syringe for Tooth Extractions in Children
The goal of this clinical trial is to learn whether a needle-free injection system can make tooth extraction less stressful for children than a conventional dental syringe.
- Conditions
- Tooth Extraction, Dental Anxiety, Procedural Pain, Anesthesia, Dental
- Trial name
- NCT07548892
- Testing
- Needle-Free Jet Injection System, Conventional Syringe Injection
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Site Preservation, Soft Tissue Healing
Site Preservation Was Performed Through an Open Healing Oral Restorative Membrane
In this study, an open healing oral restoration membrane was used for site preservation in the esthetic area after tooth extraction to maintain the space for tooth extraction and bone formation.
- Conditions
- Site Preservation, Soft Tissue Healing, Anterior Dental Aesthetic Area
- Trial name
- NCT07334067
- Testing
- site preservation surgery with open healing, site preservation surgery with close sutures
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Deep Caries, Carious Exposure of Pulp
Outcome of Selective & Nonselective Caries Removal in Permanent Teeth
Patients presenting with deep decay within permanent teeth presents a common clinical challenge to dentists. The aim of this trial is to compare the success rate of the non-selective caries removal (NSCR) and selective caries…
- Trial name
- RCT-SNCR (NCT06378814)
- Testing
- Selective Caries Removal (No Pulp Exposure), Non-Selective Caries Removal (No Pulp exposure), Partial Pulpotomy (Pulp Exposed)
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- King's College London
Extraction Sites After Removal and Bone Replacement Grafting at Extraction Sockets of Dentally Hopeless Single-rooted Teeth
To Compare Post-Extraction Use of a Novel Ethylenediaminetetraacetic Acid (EDTA) Post-operative Mouth Rinse and Daily Use EDTA Mouth Rinse and Standard 0.12% Chlorhexidine (CHX) Post-operative Mouth Rinse and Daily Use Essential Oil (EO) Mouth Rinse.
This study will compare commercially available, commonly used mouth rinses (0.12% chlorhexidine (CHX) vs. Ethylenediaminetetraacetic acid (EDTA)) for immediate post-operative and daily antiseptic use after tooth extraction and…
- Trial name
- NCT07191262
- Testing
- 0.12% CHX and Essential Oil mouthrinse, 2.6% EDTA and 0.2% EDTA mouth rinse
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Tooth Extraction, Wisdom Tooth Removal
Periodontal Regeneration at the Distal Site of Second Molars After the Extraction of Lower Included Third Molars
From an exclusively periodontal point of view, the extraction of third molars (3M) or wisdom teeth is relatively frequently recommended, either because they show reduced bone support or to avoid periodontal damage to the…
- Conditions
- Tooth Extraction, Wisdom Tooth Removal, Periodontal Regeneration
- Trial name
- NCT07059247
- Testing
- Application of Enamel Matrix Derivatives, Extraction of the impacted third molar
- Volunteers
- 24 people
- Sponsor
- Universidad Complutense de Madrid
Bleeding, Tooth Extraction
Effects of Tranexamic Acid Irrigation on Impacted Third Molar Surgery
Tranexamic acid (TXA) is an effective hemostatic agent used to reduce blood loss and the need for transfusion. It is a relatively safe drug with minimal significant side effects.
- Trial name
- NCT06806241
- Testing
- Tranexamic acid, saline irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Alveolar Ridge Preservation, Tooth Loss
Volumetric Efficacy of Alveolar Ridge Preservation
The goal of this clinical trial is to compare the effectiveness of four post-extraction socket management approaches in preserving alveolar ridge dimensions following tooth extraction in adults requiring implant-supported…
- Conditions
- Alveolar Ridge Preservation, Tooth Loss, Tooth Extraction, Tooth Extraction Site Healing
- Trial name
- ARP (NCT07812883)
- Testing
- Spontaneous Healing, d-PTFE Membrane, Leukocyte- and Platelet-Rich Fibrin (L-PRF)
- Where
- Chile
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidad del Desarrollo
Early Childhood Caries (ECC)
Zirconia Crowns Versus Extraction of Primary Anterior Teeth
Severely mutilated anterior primary teeth in preschool children are frequently managed by extraction. However, premature loss of anterior primary teeth has been associated with adverse functional, developmental and psychosocial…
- Trial name
- NCT07719478
- Testing
- Zirconia Crown, Extraction
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Passant Nagy
Periodontal Defects After Third Molar Extraction, Periodontal Disease
Comparison of Autologous Tooth and Bovine Xenograft in Periodontal Healing After Mandibular Third Molar Extraction
This study investigates the healing of periodontal defects on the distal surface of the second lower molars after the surgical extraction of impacted third molars.
- Trial name
- NCT07824518
- Testing
- Autologous Tooth Graft
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Tooth Loss in the Anterior Maxilla, Alveolar Bone Resorption
Peri-Implant Hard and Soft Tissue Changes After Immediate Implant Placement With Socket Shield and Immediate Restoration Versus Early Implant Placement in the Esthetic Zone
This randomized controlled clinical trial aims to compare peri-implant hard and soft tissue dimensional changes following immediate implant placement with the socket shield technique and immediate restoration versus early type II…
- Conditions
- Tooth Loss in the Anterior Maxilla, Alveolar Bone Resorption, Partial Edentulism of the Maxilla
- Trial name
- NCT07468760
- Testing
- Socket Shield, Early Implant Placement
- Where
- United Arab Emirates
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Tooth Loss, Dental Implant
Tissue Preservation in Immediate 1C Implants Using an Anatomical Prefabricated Healing Abutment
The goal of this clinical trial is to evaluate whether an anatomical prefabricated healing abutment (AHA) improves tissue preservation and clinical outcomes following immediate implant placement after tooth extraction in adults.
- Conditions
- Tooth Loss, Dental Implant, Clinical Trials, Randomized Controlled Trial
- Trial name
- Aharct (NCT07727980)
- Testing
- scannable anatomical healing abutment, Standard Healing Abutment for Dental Implants
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Illinois Chicago
Osteoradionecrosis of the Jaw, Medicine Related Osteonecrosis of the Jaw
L-PRF in Prevention of ORN and MRONJ Following Tooth Extractions;v3.0
Osteoradionecrosis (ORN) and medication-related osteonecrosis of the jaw (MRONJ) are debilitating complications following dental extractions in patients who have received head and neck radiotherapy or antiresorptive therapy.
- Trial name
- NCT07585123
- Testing
- L-PRF, Standard Extraction
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Swansea Bay University Health Board
Dental Calculus, Gingivitis and Periodontal Diseases
Bio-Descaling Toothpaste for Dental Calculus Reduction
Dental calculus is a calcified mineralized plaque composed primarily of calcium phosphate salts covered by an unmineralized bacterial biofilm layer.
- Conditions
- Dental Calculus, Gingivitis and Periodontal Diseases, Periodontal Diseases
- Trial name
- AntiCal (NCT07689071)
- Testing
- Bio-Descaling Powder (BDP) Toothpaste
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Wound Healing, Alveolitis of Jaw
Effect of Curcumin Topical Spray on Wound Healing After Tooth Extraction
This randomized, single-blind, controlled clinical trial aims to evaluate the effects of a topical curcumin spray on post-extraction wound healing and postoperative symptoms in adults undergoing first molar extraction.
- Conditions
- Wound Healing, Alveolitis of Jaw, Tooth Extraction, Curcumin
- Trial name
- NCT07874789
- Testing
- Curcumin Topical Spray, Chlorhexidine Topical Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istanbul University