Clinical trials: Tooth Hypersensitivity
- Condition Tooth Hypersensitivity
- Funder type Industry (pharma, biotech, devices)
- Accepts healthy volunteers yes
Dentine Hypersensitivity
The Efficacy of a Dentifrice in Providing Relief From the Pain of Dentinal Hypersensitivity
A study to compare the efficacy of a test dentifrice against a control dentifrice in reducing dentinal hypersensitivity over an eight week treatment period.
- Trial name
- NCT01592864
- Testing
- Stannous Fluoride, Sodium Monofluorophosphate
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity
A Clinical Study to Assess the Efficacy of a Calcium Sodium Phosphosilicate Toothpaste for the Relief of Dentine Hypersensitivity
The primary purpose of this study is to demonstrate the clinical efficacy of Test Toothpaste in reducing dentin hypersensitivity (DH) to an evaporative (air) stimulus, compared to a sodium fluoride reference toothpaste, after 8…
- Trial name
- NCT07802886
- Testing
- Test Toothpaste, Regular Fluoride Toothpaste
- Where
- United Kingdom
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Sensitivity
A Study to Assess the Efficacy of a Calcium Sodium Phosphosilicate Toothpaste for the Relief of Dentine Hypersensitivity
The aim of this study is to demonstrate the clinical efficacy of the Test Toothpaste containing Calcium Sodium Phosphosilicate (CSPS) in reducing Dentin Hypersensitivity (DH) to an evaporative (air) stimulus, compared to a sodium…
- Trial name
- NCT07894796
- Testing
- Test Toothpaste, Regular Fluoride Toothpaste
- Where
- Canada
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentine Hypersensitivity
The Efficacy of a Dentifrice in Providing Relief From Immediate and Short Term Relief From Dentinal Hypersensitivity
A randomised, examiner blind, two treatment arm, stratified, parallel design, single-site study in subjects with at least two sensitive teeth to compare the efficacy of a test dentifrice against that of a control dentifrice in…
- Trial name
- NCT03072719
- Testing
- Stannous Fluoride, Sodium Monofluorophosphate
- Where
- Ireland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity
Clinical Study to Evaluate the Anti-sensitivity Efficacy of a Stannous Fluoride Toothpaste in a Population of Dentin Hypersensitivity Sufferers
The aim of this study is to confirm the clinical Dentin Hypersensitivity (DH) efficacy of a 0.454 percent (%) Stannous Fluoride (SnF2) toothpaste.
- Trial name
- NCT06359028
- Testing
- Stannous fluoride toothpaste, Crest cavity protection toothpaste
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Sensitivity
A Study in Dentinal Hypersensitivity (DH) Participants to Assess the Efficacy of an Occluding Dentifrice.
This study will investigate the longitudinal efficacy of two experimental oral rinses, one containing 1.5% weight/weight (w/w) dipotassium oxalate monohydride (KOX) /0 Parts per Million (ppm fluoride) and the other 2.0% w/w KOX…
- Trial name
- NCT02753075
- Testing
- Experimental Oral Rinse 1, Experimental Oral Rinse 2, Fluoride toothpaste
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity
Assessment of the Efficacy of an Experimental Occlusion Technology Dentifrice in Dentinal Hypersensitivity
This study will evaluate the effectiveness of an experimental dentifrice containing stannous fluoride, an established dentine tubule occlusion technology, at reducing dentine hypersensitivity (DH) compared to a negative control…
- Trial name
- NCT02861664
- Testing
- Stannous fluoride (SnF2), Sodium monofluorophosphate (SMFP)
- Where
- China
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Hypersensitivity
Hypersensitivity Reduction Efficacy: 5% Potassium Nitrate Toothpaste Compared to Colgate Cavity Protection Toothpaste
Assess the clinical efficacy of 5% Potassium Nitrate Toothpaste (Colgate-Palmolive Company, New York, NY, USA) on providing dentinal hypersensitivity relief (tactile and air blast) in comparison to Colgate Cavity Protection…
- Trial name
- NCT06956599
- Testing
- test toothpaste, Control toothpaste
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Tooth Hypersensitivity
NUPRO Sensodyne Prophylaxis Paste With NovaMin Sensitivity Relief Study
The study is intended to verify through clinical measurement that the NUPRO Sensodyne Prophylaxis Paste with Novamin provides immediate sensitivity relief as well as extended relief up to 28 days.
- Trial name
- NCT01669785
- Testing
- Group C, Group A, Group B
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Dentsply International
Dentin Sensitivity
A Clinical Study to Evaluate the Anti-Sensitivity Effect of a Calcium Sodium Phosphosilicate Toothpaste in a Population of Dentin Hypersensitivity Sufferers
The aim of this study is to confirm the clinical dentin hypersensitivity (DH) efficacy of a 5 percent (%) calcium sodium phosphosilicate (CSPS) toothpaste.
- Trial name
- NCT06378008
- Testing
- CSPS toothpaste, Regular fluoride toothpaste (Crest Cavity Protection)
- Where
- Canada
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentine Hypersensitivity
Meta-analysis of Stannous Fluoride Dentifrice and the Effects on Dentine Hypersensitivity
The aim of this 11 study analysis was to compare the effect of bioavailable stannous fluoride (SnF2) on dentine hypersensitivity versus a positive or negative control dentifrice.
- Trial name
- NCT04005417
- Testing
- Stannous fluoride dentifrice, Positive control dentifrice, Negative control dentifrice
- Where
- United States
- Volunteers
- 1,036 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Dentin Sensitivity
Clinical Benefit of a Mouthrinse for the Treatment of Dentine Hypersensitivity
This study is to evaluate the benefit and tolerability of a Mouthrinse (IQP-OLP-101) in the treatment of dentine hypersensitivity.
- Trial name
- NCT03232255
- Testing
- Mouthrinse (IQP-OLP-101)
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- InQpharm Group
Dentin Sensitivity
Impact of Long Term Management of Dentine Hypersensitivity (DH) With a Daily Use Anti-sensitivity Toothpaste on the Quality of Life Related to Oral Health
This multicentre, non-comparative design study will monitor the impact of long term management of DH with daily use of a sensitivity toothpaste on the quality of life of a population of sensitivity sufferers.
- Trial name
- NCT02752958
- Testing
- stannous fluoride
- Where
- 2 sites in United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Sensitivity, Tooth
Clinical Evaluation of OBU When Used for Indirect Dental Restorations
The objective of this study is to evaluate the clinical safety and performance of Optibond Universal (OBU), a single component universal dental adhesive intended for indirect dental restorations according to manufacturer's…
- Trial name
- NCT06002880
- Testing
- Optibond Universal
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Kerr Corporation
Dentin Sensitivity
A Study to Assess Efficacy of an Experimental Oral Rinse in Providing Long Term Relief From Dentinal Hypersensitivity
To investigate the efficacy of an experimental oral rinse, containing 1.5% potassium oxalate (KOX) and 0 parts per million (ppm) fluoride in relieving dentine hypersensitivity (DH) after 8 weeks use compared with a placebo oral…
- Trial name
- NCT03238352
- Testing
- Potassium oxalate, Sodium fluoride
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Enamel Erosion
Meta-analysis of Stannous Fluoride and the Effects on Enamel Erosion
The aim of this 5 study analysis was to compare the effect of bioavailable stannous fluoride (SnF2) dentifrices to assess enamel erosion protection in-situ using surface profilometry.
- Trial name
- NCT04006470
- Testing
- Stannous fluoride dentifrice, Positive control dentifrice, Negative control dentifrice
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Dentin Hypersensitivity
A Study Evaluating Oral-Health-Related Quality of Life and Treatment Patterns Among Dentin Hypersensitivity Sufferers
The primary purpose of this study is to characterize changes in Oral-Health-Related Quality of Life (OHrQoL), as measured by the Dentin Hypersensitivity Experience Questionnaire (DHEQ) over a 12-month period.
- Trial name
- NCT07337109
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Sensitivity
The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity(DH)
This single centre, comparative design study will be used to investigate the efficacy of an experimental stannous fluoride containing dentifrice in relieving dentinal hypersensitivity (DH) after short term use compared with a…
- Trial name
- NCT02751450
- Testing
- Stannous Fluoride dentifice, Sodium Monofluorophosphate dentifrice
- Where
- United Kingdom
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity
A Pilot Clinical Study to Evaluate the Safety and Efficacy of Marketed Oxalate Strips Compared to a Marketed Safety Pen
This pilot study will evaluate the safety and effectiveness of a marketed sensitivity strip on existing dentinal hypersensitivity compared to a marketed sensitivity pen.
- Trial name
- NCT02384044
- Testing
- Crest® Sensi-Stop™ Strips, Colgate® Sensitivity Relief Pen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Dentin Sensitivity
Real-World Study of a Calcium Sodium Phosphosilicate Anti-Sensitivity Toothpaste for Dentin Hypersensitivity Relief
The aim of this study is to evaluate the impact of a commercially available desensitizing dentifrice containing 5 percent (%) Calcium sodium phosphosilicate (CSPS) on oral health related quality of life (OHrQoL) in a DH (Dentin…
- Trial name
- NCT07300540
- Testing
- Calcium sodium phosphosilicate (CSPS) Toothpaste
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- HALEON