Clinical trials: Tooth Hypersensitivity
Medicaments Substances in Therapeutic Use
Potassium Oxalate and Potassium Nitrate and Post-bleaching Sensitivity
Objectives: This study will determine the effectiveness of the use of desensitivity gels prior in office bleaching on risk and intensity of tooth sensitivity caused by in-office bleaching using 35% hydrogen peroxide.
- Trial name
- NCT02941653
- Testing
- Potassium nitrate 2% gel, Potassium oxalate 5% gel
- Where
- Brazil
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Dentine Sensitivity
A Pilot Study to Substantiate the Use of the Jay Sensitivity Sensor Probe
Subjects with at least two teeth with dentinal hypersensitivity and who meet the study criteria will be enrolled onto this double blind, randomised, parallel, controlled clinical trial.
- Trial name
- NCT02789618
- Testing
- A01, B99, M89
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Oral Hygiene, Toothbrushing
Open-label Trial Evaluating Four Oral Hygiene Regimens Using a Manual Toothbrush, Toothpaste, and Mouthwash
The purpose of this open-label, randomized controlled clinical trial, is to provide preliminary clinical data (efficacy on plaque and gingival sensitivity, and safety and tolerability of two types of toothpaste, a mouthwash, and…
- Conditions
- Oral Hygiene, Toothbrushing, Dental Plaque
- Trial name
- NCT05999175
- Testing
- the toothpaste is used with a standard toothbrush without any claims 3 times a day after the main meals for 28 days., the mint toothpaste and mouthwash are used with the scalar toothbrush 33 medium with antibacterial " Spazzolino tau-marin®" 3 times a day after the main meals for 28 days., subjects of this group will use their routine oral hygiene products.
- Where
- 2 sites in Italy
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Biokosmes Srl
Dentine Sensitivity
Evaluation of the Effect of the Gel on Sensitive Teeth
The goal of this study is to learn if a tooth gel works to alleviate teeth hypersensitivity in adults. It will also learn about the safety of the product.
- Trial name
- NCT07596797
- Testing
- Desensitizing tooth gel
- Where
- Spain
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Lacer S.A.
Dental Hypersensitivity, Teeth Whitening
Effectiveness of 16% Carbamide Peroxide in Reducing Hypersensitivity During Alternate-day Home Bleaching
The concentration of 16% carbamide peroxide is the highest concentration that European regulations allow for use in home whitening (Council directive 2011/84/EU).
- Trial name
- NCT06035588
- Testing
- Daily whitening, Alternate whitening
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Dentin Sensitivity
Effect of Laser and Potassium Nitrate Application on the Sensitivity Control in Bleached Teeth
To investigate the effects of desensitizing agents on the dental bleaching process, testing the hypothesis that they may control dental sensitivity.
- Trial name
- NCT03434782
- Testing
- In-office dental bleaching, Low Level Laser Therapy, 5% potassium nitrate / 2% sodium fluoride gel
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Color, Bleaching Sensitivity
Whitening Efficacy and Tooth Sensitivity of Different Concentrations of Hydrogen Peroxide Photoactivated With Violet or Blue LEDs
This is a randomized, controlled, double-blind and repeated-measures clinical trial evaluated the photoactivation of hydrogen peroxide gels in different concentrations with blue or violet LED in terms of whitening efficacy and…
- Trial name
- NCT06165458
- Testing
- 6% hydrogen peroxide gel + violet LED, 6% hydrogen peroxide gel + blue LED, 35% hydrogen peroxide gel + violet LED
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Sensitivity, Tooth
Dentinal Hypersensitivity Reduction Efficacy Study
Assess the clinical efficacy of CSPR Toothpaste containing 8% arginine to provide dentinal hypersensitivity relief
- Trial name
- NCT06960148
- Testing
- CSPR Toothpaste, Colgate Dental Cream Toothpaste
- Where
- China
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dentin Sensitivity, Molar Incisor Hypomineralization
MIH and Hypersensitivity in Children
The aim of this study was to evaluate the efficacy of the association of casein phosphopeptide plus amorphous calcium phosphate (CPP-ACPF) mousse and photo-bio-modulation therapy (PMBT) (diode laser, RAFFAELLO 980 BIO - Dental…
- Trial name
- NCT05705037
- Testing
- CPP-ACPF, PBMT, CPP-ACPF+PBMT
- Where
- Italy
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Brescia
Sensitivity, Tooth
Postoperative Sensitivity Following Placement with Different Restorative Materials in Vital Posterior Teeth
There is a lack of long-term clinical studies comparing different restorative materials; most of the available studies have only looked at class I cavities or examined post-operative sensitivity in non-caries cervical lesions.
- Trial name
- GCP (NCT05882760)
- Testing
- Tetric N Bond Universal®, Self Etch Tetric N Bond Universal®, GC Fuji IX, GC, Japan®
- Where
- Pakistan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Liaquat University of Medical & Health Sciences
Tooth Hypersensitivity
NUPRO(r) Sensodyne Prophylaxis Paste With NovaMin(r)Sensitivity Relief Study
The study is intended to verify through clinical measurement that the NUPRO Sensodyne Prophylaxis Paste with Novamin provides immediate sensitivity relief as well as extended relief up to 28 days.
- Trial name
- NCT01610167
- Testing
- NUPRO Classic Prophy Paste, NUPRO Sensodyne Prophy Paste with Novamin with fluoride., NUPRO Sensodyne Prophy Paste with Novamin without fluoride.
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Dentsply International
Dentin Hypersensitivity
Desensitizers in Reducing Post Tooth Preparation Sensitivity for a Fixed Dental Prosthesis
The main purpose of the present study was to evaluate and compare the effectiveness of three kinds of commercially available desensitizing agents: Gluma, Sheildforce plus, and Telio CS desensitizers in reducing the pre- and…
- Trial name
- NCT04512625
- Testing
- Desensitizers
- Where
- Saudi Arabia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Jazan
Tooth Whitening, Sensitivity
Effects of Desensitizing Dentifrices on the Reduction of Pain Sensitivity Caused by In-office Dental Whitening
Introduction: The pain sensitivity associated with whitening is the main problem reported by patients during dental whitening, and the use of desensitizing dentifrices is an alternative for the treatment of sensitivity.
- Trial name
- NCT03019224
- Testing
- Selection and preparation of the volunteers, Evaluation of the tooth color, Relative isolation
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Dentin Sensitivity
A Pilot Study to Assess Nominal Versus Controlled Stimuli on Dentinal Hypersensitivity
This pilot study will evaluate the use of nominal stimuli to assess dentinal hypersensitivity response relative to a clinically-controlled stimulus.
- Trial name
- NCT02406573
- Testing
- Crest® Sensi-Stop™ Strips
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Dentin Hypersensitivity
A Comparison Study of Hypersensitivity Treatment
The goal of this clinical trial is to evaluate the effect of 3M™ Clinpro™ Fluoride Aqueous Solution (experimental) on Dentin Hypersensitivity (DHS) in comparison to 3M™ Vanish™ (commercialized, control] in patients who have DHS.
- Trial name
- NCT05768373
- Testing
- 3M™ Clinpro™ Fluoride Aqueous Solution, 3M™ Vanish™
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Dentin Sensitivity
Effect of Glutaraldehyde on Dentin Hypersensitivity After Non-surgical Periodontal Treatment
This randomized, placebo-controlled, triple-blind trial aims to evaluate the effect of glutaraldehyde associated or not with 37% phosphoric acid conditioning on dentin hypersensitivity reduction after non-surgical periodontal…
- Trial name
- NCT04207450
- Testing
- Phosphoric Acid 37% + Solução aquosa de glutaraldeído a 5%
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Dentin Hypersensitivity
Effect of Chemical and Light Bleaching Techniques on Color Change, Dentin Hypersensitivity and Patient Satisfaction
Aim of The Study This study aims is to evaluate color change, dentin hypersensitivity and patient satisfaction after different bleaching techniques at different time intervals.
- Trial name
- NCT07669324
- Testing
- Light activated bleaching, Chemically activated bleaching
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nahda University
Tooth Discoloration, Hypersensitivity
Composite Repair Using Silane Coupling Agent
Evaluation the influence of the use of silane coupling agent application as a separate step versus application of silane or acid resistance silane containing adhesives on the clinical performance of repaired posterior resin…
- Conditions
- Tooth Discoloration, Hypersensitivity, Tooth Fracture, Dental Restoration Failure of Marginal Integrity
- Trial name
- NCT06392685
- Testing
- Silane coupling agent, Adhesive containing silane.(Intervention 1 ), Acid resistance silane containing adhesive.(Intervention 2)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Root Sensitivity
Propolis as a Treatment for Cervical Dentin Hypersensitivity
Fluoridated desensitizers the frequently used for the treatment of dentin hypersensitivity (DH) with Iontophoresis. This study aimed to evaluate and compare the immediate and long-term effects of 10% Propolis with 2% sodium…
- Trial name
- NCT05588518
- Testing
- desensitizing agents -10% Propolis
- Where
- Saudi Arabia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- King Khalid University
Dentin Sensitivity
Clinical Study to Investigate the Ability of a Stannous Fluoride Toothpaste to Protect From Dentine Hypersensitivity
The purpose of this study is to investigate and characterize the Dentine Hypersensitivity (DH) protection profiles of a 0.454 percent (%) Stannous Fluoride (SnF2) toothpaste and a regular fluoride toothpaste, in response to…
- Trial name
- NCT06733285
- Testing
- Sensodyne Rapid Relief, Colgate Cavity Protection
- Where
- United Kingdom
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- HALEON