Clinical trials: Tooth Loss
Missing Teeth
A Full-Arch Implant- Supported Prosthesis in the Upper and/or Lower Jaw-USA
This study follows subjects who have agreed with their dentist that their failing teeth or missing teeth all need replacing. This study follows their standard routine care with some additional assessments.
- Trial name
- NCT03655990
- Testing
- Treatment with the JUVORA™ Dental Disc
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Juvora Ltd.
Tooth Loss
An Observational Study of the T3 Pro Dental Implant System
A prospective, observational, multicenter study where 60 patients needing implants in the maxilla or mandible will be enrolled. The patients will be restored with a final prosthesis no later than 4 months following implant…
- Trial name
- Spike (NCT05498662)
- Testing
- T3 Pro dental implant system
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ZimVie
Bone Cysts, Bone Atrophy
Gene-activated Bone Substitute for Maxillofacial Bone Regeneration
The purpose of this study is to evaluate the safety and efficacy of the gene-activated bone substitute consisting of octacalcium phosphate and plasmid DNA encoding vascular endothelial growth factor (VEGF) for maxillofacial bone…
- Conditions
- Bone Cysts, Bone Atrophy, Bone Deformity, Bone Fracture
- Trial name
- NCT03076138
- Testing
- Gene-activated matrix (OCP + plasmid DNA with VEGF gene)
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- Histograft Co., Ltd.
Teeth Loss, Bone Loss
Maxillary Sinus Elevation With Bio-Oss or Straumann BoneCeramic
The purpose of the study was to test a clinically relevant non-inferiority of Straumann BoneCeramic treatment compared to Bio-Oss treatment 180 to 240 days after sinus grafting procedure.
- Trial name
- NCT00901121
- Testing
- Straumann BoneCeramic, Bio-Oss
- Where
- 8 sites in Italy
- Volunteers
- 48 people
- Sponsor
- Institut Straumann AG
Tooth Loss, Edentulism
PMCF Study on the Effectiveness and Safety of BIODENTOSS® and DWC® Dental Implants and Superstructures
This prospective, single-center, interventional post-market clinical follow-up (PMCF) study aims to evaluate the early-term (24 months post-implantation) safety and efficacy of CE-marked BIODENTOSS® and DWC ® Dental Implants and…
- Trial name
- NCT07633665
- Testing
- BIODENTOSS Bone-Level Dental Implant and Superstructures, DWC Bone-Level Dental Implant and Superstructures
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Değirmenci Otomotiv ve Metal Endüstri A.Ş.
Tooth Loss
Bone Level Tapered Multi-Center Study
The aim of this randomized, controlled, multi-center study is to assess the clinical and radiographic outcomes of using a Straumann® Bone Level Tapered implant for immediate implantation following extraction of a tooth in the…
- Trial name
- NCT02569671
- Testing
- Straumann Bone Level Tapered Implant - Immediate Placement, Straumann Bone Level Tapered Implant - Delayed Placement
- Where
- 3 sites in United States
- Volunteers
- 53 people
- Sponsor
- Institut Straumann AG
Tooth Loss
Performance Evaluation of FullCeram Implants in Single Tooth Gaps
Straumann Monotype FullCeram implants serve as a suitable alternative for implant therapy especially in the aesthetic zone The survival rate of Straumann Ceramic implants should be at least 85% (max 6 implant losses out of 40…
- Trial name
- NCT02163395
- Testing
- FullCeram implant
- Where
- 3 sites in Germany
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Institut Straumann AG
Tooth Loss
An RCT Comparing Xenograft and Allograft for Ridge Preservation
To compare the effectiveness of demineralized freeze-dried bone allograft + cross-linked collagen membrane with xenograft + non-cross-linked collagen membrane for posterior extraction socket ridge preservation.
- Trial name
- NCT02330523
- Testing
- allograft + x-link collagen membrane, xenograft + non-x-link collagen
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- McGuire Institute
Partially Edentulous Jaw
Study on OsseoSpeed™ TX Implants in the Upper Jaw in a Chinese Population
The purpose of this study is to investigate the clinical efficacy of OsseoSpeed™ TX implants in a Chinese population by evaluation of marginal bone level alteration, implant stability and implant survival in the posterior maxilla…
- Trial name
- NCT01389245
- Testing
- OsseoSpeed™ TX
- Where
- 3 sites in China
- Volunteers
- 42 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Tooth Loss
A Clinical Study of the TSX Dental Implant System (Xpresso)
A prospective, observational, multicenter study where 62 patients needing implants in the maxilla or mandible will be enrolled. The patients will be restored with a final prosthesis no later than 4 months following implant…
- Trial name
- Xpresso (NCT06571812)
- Testing
- TSX
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- ZimVie
Implant Clinical Survival, Dental Implant Bone Loss
A Multi-center Study to Evaluate Bone Loss, Survival Rate and Stability of ICE Implant
The current prospective clinical study's aim is to determine ABT's ICE implant survival rate, crestal interproximal bone resorption during 24 months post implant insertion and to assimilate the drilling sequence during the…
- Trial name
- ICE (NCT01960361)
- Testing
- ICE dental implant
- Where
- Israel
- Volunteers
- 35 people
- Sponsor
- Alpha - Bio Tec Ltd.
Dental Atraumatic Restorative Treatment
Clinical Evaluation of Enamel Microhardness Using Tooth Whitening Agents
The investigator will review the medical history taken by the participants' orthodontist that determined participants eligibility to participate in this study on the first appointment.
- Trial name
- NCT07165366
- Testing
- Carbamide Peroxide 10%, Hydrogen Peroxide
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ultradent Products, Inc.
Tooth Loss
Comparison of Straumann BoneCeramic vs. Allograft Bone in Extraction Sockets
The primary objective of this study is to evaluate the implant stability at the time of abutment placement on implants placed in healed extraction sockets treated with Straumann BoneCeramic (SBC) versus Freeze Dried Bone…
- Trial name
- NCT00782236
- Testing
- Bone Graft Material
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Institut Straumann AG
Unilateral Hearing Loss
Bone Conduction Auditory Performance Via the Tooth for Single-Sided Deafness
The purpose of this study is to determine the safety and efficacy of using bone conduction via the teeth to treat Single-Sided Deafness (SSD).
- Trial name
- NCT00977314
- Testing
- The Sonitus Bone Conduction Hearing System, SoundBite, SoundBite Hearing System
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- Sonitus Medical Inc
Jaw, Edentulous, Partially
Study to Compare Marginal Bone Loss Around Implants From Two Dental Implant Systems.
The purpose of this study is to compare marginal bone level changes between ASTRA TECH Implant System; Fixture ST and Biomet 3i; Osseotite® Implants.
- Trial name
- NCT00746187
- Testing
- ASTRA TECH Implant System; Fixture ST: Ø 4.5 cm in lengths of 9, 11 and 13 mm., 3i Osseotite® implant: Ø 4.0 in lengths of 8.5, 10, 11.5 and 13 mm
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Tooth Loss
A Comparative, Randomized, Prospective, Performance Evaluation of Abutments in Single Tooth Gaps
Immunologically evaluation of myeloperoxidase level as indicator for inflammatory reactions on modified surface abutments compared to machined surface abutments.
- Trial name
- NCT02219139
- Testing
- ESTA abutment Roxolid
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Institut Straumann AG
Tooth Loss
Study Comparing Osseodensification With Standard Drilling
The purpose of this study is to examine how Osseodensification, a well-defined bone preparation procedure utilizing special densifying burs (a tool to prepare bone) compares to the standard drilling procedure utilizing regular…
- Trial name
- OD/SD (NCT04779203)
- Testing
- Osseodensification Densah Bur
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Jackson Implant Surgery
Tooth Loss, Soft Tissue Deficiency
A Clinical Study to Investigate Collagen Matrix 10808 for Soft Tissue Volume Augmentation Around Single Implants
The objective of this study is to investigate the safety and the function of the collagen Matrix 10808 in humans and to compare it versus the standard therapy, the transplantation of the autologous connective tissue graft.
- Trial name
- NCT02356770
- Testing
- Collagen Matrix 10808, Connective tissue graft
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Geistlich Pharma AG
Bone Loss
Comparison of Straumann Bone Ceramic and Bio-Oss With Guided Tissue Regeneration for Alveolar Ridge Preservation
The purpose of this study is to compare a new biomaterial with an already existing treatment principle (Bio-Oss/Bio-Gide) with regard to their ability to preserve the dimensions of the alveolar ridge and to promote bone…
- Trial name
- NCT00900718
- Testing
- Straumann Bone Ceramic, Bio-Oss
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- Institut Straumann AG
Teeth Loss
Controlled Pilot Study to Assess Soft Tissue Reaction at the Crestal Part of a Dental Implant With ESTA Surface
This study will investigate the effect on the soft tissue that is in contact with a dental implant with a modified surface of the neck (the part of the implant that is above the bone and in contact with the soft gum tissue).
- Trial name
- NCT02159183
- Testing
- Standard Plus ESTA STL Roxolid implant, Standard Plus STL implant
- Where
- 4 sites in Switzerland
- Volunteers
- 43 people
- Sponsor
- Institut Straumann AG