Clinical trials: Tooth Plaque
Gingival Hyperplasia, Dental Plaque
Clinical Efficacy of Chlorhexidine Varnish in Reducing Gingival Hyperplasia, Plaque Accumulation, and White Spot Lesions in Orthodontic Patients
This study investigates whether applying a chlorohexidine varnish (a dental coating) reduces gum overgrowth, plaque buildup, and early tooth decay (white spots) in patients with braces.
- Conditions
- Gingival Hyperplasia, Dental Plaque, Tooth Demineralization
- Trial name
- NCT07115784
- Testing
- Chlorhexidine Varnish
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Molar Incisor Hypomineralization, Oral Health
Prevalence, Etiology and Effects on Oral Health and Life Quality of Molar Incisor Hypomineralization
Molar incisor hypomineralization (MIH) can lead to many clinical conditions and affect oral health-related quality of life (OHRQoL).
- Conditions
- Molar Incisor Hypomineralization, Oral Health, Child, Only, Pediatric ALL
- Trial name
- NCT05779332
- Testing
- survey application
- Where
- Turkey (Türkiye)
- Volunteers
- 655 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Dental Plaque, Gingivitis
A Clinical Study Investigating the Effect of an Experimental Toothpaste Containing Stannous Fluoride in Improving Gingival Health
The aim of this 4-week clinical study is to evaluate the ability of an experimental toothpaste, containing 0.454 percent (%) Stannous Fluoride (SnF2), 0.3% Zinc Chloride (ZnCl2) and 1% Alumina, to improve gingival health and…
- Trial name
- NCT06602466
- Testing
- Test toothpaste, Colgate Cavity Protection Toothpaste
- Where
- United Kingdom
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- HALEON
Plaque, Dental
Single Brushing Plaque Removal Efficacy of a Battery-powered Toothbrush and a Manual Toothbrush
To evaluate and compare the plaque removal efficacy of a battery-powered toothbrush and a manual toothbrush following a single brushing.
- Trial name
- NCT06126445
- Testing
- Battery operated toothbrush, Manual toothbrush
- Where
- Canada
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Dental Plaque Accumulation, Nanoparticles
Comparing the Antiplaque Effects of Novel Titania Nanoparticle Infused Fluoride Varnish vs Conventional Fluoride Varnish in Fixed Orthodontic Patients.
In this study the investigators aimed to explore the antibiofilm effect of fluoride varnish loaded with titania nanoparticles synthesized from moringa oleifera leaves extract vs conventional fluoride varnish in multibracket fixed…
- Conditions
- Dental Plaque Accumulation, Nanoparticles, Fluoride Varnishes
- Trial name
- NCT07180849
- Testing
- Fluoride varnish, Novel titania nanoparticle infused fluoride varnish
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Dental Plaque, Calculus, Dental
Electric Toothbrush Efficacy in Preventing Dental Plaque Development
The present study will be the first to compared dental plaque quantitation between an oscillating-rotating electric toothbrush and a manual toothbrush with a new QLF technology.
- Trial name
- E-TOOTH (NCT06358482)
- Testing
- oscillating toothbrush, standard manual toothbrush
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Riccardo Polosa
Caries,Dental, Pain
Comparative Evaluation of SMART Hall Technique Vs. Conventional SS Crown in Primary Molars: a Randomized Clinical Trial
Dental caries, particularly in primary molars, significantly affects children's oral health and overall well-being. Traditional management with stainless steel crowns (SSCs) involves significant tooth reduction and advanced…
- Conditions
- Caries,Dental, Pain, Plaque, Dental, Gingival Bleeding
- Trial name
- RCT (NCT06453005)
- Testing
- SMART Hall Technique or procedure
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- C K S Teja Institute Of Dental Sciences & Research
Dental Plaque
Analyzing the Effect of Air Polishing on Tooth Surfaces With Two Imaging Methods
Micro-CT is a non-destructive imaging method with high resolution and allows to examine all tooth structures individually. Pre- and post-application images obtained by micro-CT can be superimposed and differences can be precisely…
- Trial name
- NCT05196490
- Testing
- Micro-CT, CAD/CAM
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Plaque, Dental, Gingivitis
Clinical Investigation to Assess the Efficacy of Manual Toothbrushes in the Reduction of Plaque and Gingivitis.
Qualified subjects will be enrolled and randomized to one of the two study groups based on their initial Plaque and Gingivitis scores. Subjects will be instructed to use the products according to the instructions provided.
- Trial name
- NCT06565897
- Testing
- Test regimen, Control regimen
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Plaque, Dental Plaque Accumulation
Effect of Different Products to Support Plaque Control During Daytime
The goal of this clinical trial is to test if the additional use of different commercially available products for a better breath and plaque reduction, taken during daytime between morning and evening tooth brushing, can reduce…
- Conditions
- Dental Plaque, Dental Plaque Accumulation, Mouthwashes, Chewing Gum
- Trial name
- NCT07382310
- Testing
- Oral B Pro-Health Multi-Protection Mouth Rinse refreshing mint without alcohol (0.07% CPC), Listerine Total Care mouth rinse without alcohol, Colgate total advanced pro-shield mouth rinse without alcohol (0.075% CPC)
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Dental Plaque
Efficacy of Miswak in Oral Hygiene Maintenance
Miswak has been recommended by world health organization for oral hygiene because of its availability, beneficial effect and affordability.
- Trial name
- NCT04561960
- Testing
- Fluoride toothpaste, Toothpaste Product, Toothbrush
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Dental Plaque
Evaluation of Toothpaste on Dental Plaque
The aim of this study is to compare the plaque reduction efficacy of toothpaste to a marketed active magnesium toothpaste with single-use brushing in children.Our study will consist of 50 people between the ages of 9-12.
- Trial name
- NCT05868590
- Testing
- Toothpaste
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University
Plaque, Dental, Gingivitis
Efficacy of a Toothpaste in Reducing Plaque, Gingivitis, and Gingival Bleeding
To assess the efficacy of a toothpaste containing chitosan in reducing plaque, gingivitis, and gingival bleeding, compared with Colgate Cavity Protection Toothpaste
- Trial name
- NCT07499115
- Testing
- Toothpaste containing chitosan, Colgate Cavity Protection Toothpaste
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Oral Hygiene, Oral Health, Dental Plaque
Essential Oil Mouthwash - Oral Hygiene
Background Inadequate oral health can further compromise general health, particularly in elderly patients who are more susceptible to tooth loss, periodontal disease, and oral infections.
- Conditions
- Oral Hygiene, Oral Health, Dental Plaque, Respiratory Tract Infections (RTI)
- Trial name
- EOMOH-RCT (NCT07887074)
- Testing
- Essential oil mouthwash, Chlorhexidine gluconate alcohol-free mouthwash, Povidone-iodine alcohol-free mouthwash
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- China Medical University, Taiwan
Dental Plaque
Evaluate Dental Plaque Benefit of a Preventive Treatment Gel
The objective of the study is to evaluate anti-plaque efficacy of a preventive treatment gel in a modified 4-day plaque model.
- Trial name
- NCT03546491
- Testing
- Preventive Gel, Marketed Control
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Gingivitis
Powered Toothbrush Versus Manual Toothbrush on Plaque and Gingivitis After a Six-Week Period of Home Use
The goal of this clinical trial is to learn if powered toothbrushing is more effective than manual toothbrushing in removing dental plaque. It will also learn about the safety of power toothbrushing.
- Trial name
- NCT07691814
- Testing
- power toothbrush, manual toothbrush
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Dental Caries (Diagnosis), Dental Plaque
Clinical Assessment of Caries and Dental Plaque Based on Auto-fluorescence Imaging System
The purpose of this study was to evaluate the applicability of auto-fluorescence imaging system to detect and quantify caries and dental plaque.
- Conditions
- Dental Caries (Diagnosis), Dental Plaque, Optical Imaging
- Trial name
- NCT03038412
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hui Chen
Oral Hygiene, Dental Plaque
Evaluation of the Effect of Oil Pulling
The objectives of this study were to evaluate the inhibitory effect on plaque and the tooth discoloration associated with agents used in the chemical plaque control of oil pulling in comparison with chlorhexidine-containing…
- Trial name
- NCT05304338
- Testing
- Chlorhexidine, Oil Pulling, Distilled Water
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Dental Plaque, Oral Hygiene
Efficacy of Manual Toothbrushes in Removing Dental Plaque
This clinical methodology development study will evaluate the plaque removal efficacy of four marketed manual toothbrushes, with differing bristle types and brush head designs, in healthy dentate participants.
- Trial name
- NCT04025684
- Testing
- Oral B Indicator 123, Dr Best Original, Dr Best Multi Expert
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dental Plaque
A Study to Investigate the Antimicrobial Activity of 2 Test Toothpastes
The aim of this exploratory study is to assess the ability of two test toothpastes containing 0.6% w/w zinc chloride stabilised with sodium citrate in a sodium lauryl sulfate (SLS)-containing base to reduce glycolytic metabolism…
- Trial name
- NCT02856880
- Testing
- Test zinc-IPMP toothpaste, Test zinc non- IPMP toothpaste, Positive control
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline