Clinical trials: Tooth Plaque
Gingivitis, Dental Plaque
A Clinical Study Investigating the Effects of a Dentifrice Containing 67% Sodium Bicarbonate When Used Twice Daily for 12 Weeks on Gingivitis Treatment and Plaque Removal
The main goal of this study is to evaluate and compare the efficacy of an on-market dentifrice containing 67 percent (%) sodium bicarbonate and 0.31% sodium fluoride to a reference regular fluoride dentifrice on treating gingival…
- Trial name
- NCT05654662
- Testing
- Corsodyl Original Dentifrice, Colgate Cavity Protection Dentifrice
- Where
- United Kingdom
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- HALEON
Attention Deficit and Hyperactivity Disorder, Dental Plaque
Plaque Removal Efficacy of Electric Toothbrushes in ADHD
A total of 52 children, 26 of whom were diagnosed with Attention Deficit Hyperactivity Disorder (ADHD) as the experimental group and 26 healthy with no systemic disease as the control group, were included in the study.
- Trial name
- NCT05935254
- Testing
- Plaque removal efficacy of children's electric toothbrush (Oral-B D100 Vitality; Procter & Gamble, Cincinnati, OH, United States), Plaque removal efficacy of children's soft manual toothbrush (Oral-B Stages 6-12 years; Procter & Gamble, Cincinnati, OH, United States)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Gingivitis
Effectiveness of the Use of Dental Floss
Bacterial plaque-induced gingivitis is considered the most common oral disease in dentate individuals and the most frequent type of periodontal disease.
- Trial name
- NCT04909840
- Testing
- Instructions oral hygiene with toothbrush plus dental floss, Instructions oral hygiene with toothbrush only
- Where
- Brazil
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
Dental Caries, Bleeding on Probing
Evaluating Methods of Dental Health Instructions on the Oral Health Indices of 12-18-year-old Patients With Fixed Orthodontics
The goal of this clinical trial is to learn which type of oral health education works best to help 12-18-year-old participants with fixed orthodontic appliances (braces) keep their mouths healthy.
- Conditions
- Dental Caries, Bleeding on Probing, Gingival Index, Plaque Index
- Trial name
- NCT07667283
- Testing
- Verbal Oral Hygiene Instruction, Pamphlet-Based Oral Hygiene Instruction, Video-Based Oral Hygiene Instruction
- Where
- Iran
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Dental Plaque, Gingivitis
A Study Investigating Gingival Crevicular Fluid Biomarkers Following Use of a Commercially Available Toothpaste Containing Stannous Fluoride
The aim of this study is to evaluate the feasibility, sensitivity, and interpretability of gingival crevicular fluid (GCF) cytokine biomarkers as early indicators of tissue recovery following use of commercial dentifrice compared…
- Trial name
- NCT07842042
- Testing
- Test Toothpaste, Regular Fluoride Toothpaste
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- HALEON
Plaque, Dental, Gingivitis
Imaging-based Assessment of Oral Biofilm and Gingival Health
The purpose of this research study is to develop a better way of measuring the health of patients' mouth using photographs and imaging software.
- Trial name
- NCT05470023
- Testing
- OTC Toothpastes or Mouthrinses
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Dental Plaque
Vertical vs Horizontal Brushing: a Randomized Split-mouth Clinical Trial
The aim of this randomized, single-blind, split-mouth design, clinical trial was to evaluate the effectiveness in plaque removal of the vertical and the horizontal brushing methods. Trauma on soft tissues were also registered.
- Trial name
- NCT01900353
- Testing
- brushing methods
- Where
- Italy
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Milan
Gingivitis, Plaque
Safety and Efficacy of the ToothWave -12 Weeks Calculus Study
The objective of the study is to evaluate the safety and efficacy of the home-use device Silk'n toothbrush (ToothWave) for the improvement in dental health through the reduction of plaque, gingivitis, and calculus.
- Conditions
- Gingivitis, Plaque, Calculus, Dental
- Trial name
- NCT04092075
- Testing
- RF-utilizing powered toothbrush
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Home Skinovations Ltd.
Dental Caries and Streptococcus Mutans Count
Impact of Maternal Xylitol Consumption on Mutans Sterptococci
The study was designed to determine whether maternal xylitol consumption through regular chewing of xylitol gums can affect the salivary mutans streptococci (MS), dental caries, and dental plaque levels of their children.
- Trial name
- NCT02036151
- Testing
- xylitol, fluoride varnish application
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Healthy, Adolescent
GumChucks vs Interdental Brushes in Plaque Removal.
This study compared two ways of cleaning between the teeth, Gumchucks (a new handled dental flossing system) and interdental brushes, in Lebanese adolescents aged 10-15 years.
- Conditions
- Healthy, Adolescent, Dental Plaque, Gingivitis
- Trial name
- NCT07140068
- Testing
- Handled dental flossing system (GumChucks®), Interdental Brush
- Where
- Lebanon
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beirut Arab University
Dental Plaque, Gingival Bleeding
Comparison Between Interdental Brush and Water Floss on Plaque Accumulation and Gingival Inflammation in Patients Undergoing Fixed Orthodontic Treatment.
The goal of this clinical trial is to test the ability of water flosser to remove plaque and reduce gingival inflammation in patients undergoing fixed orthodontic treatment.
- Trial name
- NCT07240428
- Testing
- Interdental brush, Water floss
- Where
- Jordan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Dental Plaque
Investigation of Dental Plaque and Gingival Index
Investigation of inhibitory effect of prototype toothpaste on dental plaque formation via modified gingival margin plaque index method.
- Trial name
- NCT00759031
- Testing
- Sodium Monofluorophosphate, Triclosan/Fluoride/Copolymer
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Plaque, Gingivitis
Assessing the Effects of Three Oral Care Regimens
Assessing the effects of three oral care regimen on plaque, gingivitis, and tooth whitening: A randomized, person-centric, comparative effectiveness clinical research study by the Practitioners Engaged in Applied Research and…
- Trial name
- NCT02940821
- Testing
- Toothbrushing, Fluoridated Dentifrice (.15% sodium monofluorophosphate), Fluoridated Dentifrice Whitening System (.454% stannous fluoride with 2% hydrogen peroxide)
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Pearl Network
Dental Decay, Periodontal Abscess
ONE-1 Oral graNd Est 1
This study is about the assessment of two oral telemedecine tools compared to an intra oral clinical examination used as a reference among elderly persons living in nursing home.
- Conditions
- Dental Decay, Periodontal Abscess, Periodontitis, Gingivitis
- Trial name
- ONE (NCT05089214)
- Testing
- Intra oral cameras
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Plaque Control
Comparison of Soft Toothbrush and Brushless Cleaner in Their Ability to Remove Plaque From Teeth
The aim of this study is to observe whether a brushless cleaning device can be equally as effective in removing plaque from the teeth as a soft toothbrush.
- Trial name
- NCT01994278
- Testing
- Peri Clean
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Peri-Swab, LLC
Healthy
Effect of Xylitol-based Chewing Gums, Sugar-free and Sugared, on Salivary Flow and pH in Young Adults
This study was planned to evaluate the effects of xylitol-based chewing gums, sugar-free and sugared, on salivary flow and pH in young adults.
- Trial name
- NCT06370091
- Testing
- Gum of Xylitol, Gum of sugar free, Gum of sugar
- Where
- Ecuador
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Católica de Cuenca
Dental Plaque, Gingivitis
The Clinical Investigation of a New Toothpaste Containing Stannous Fluoride as Compared to a Commercially Available Fluoride Toothpaste in Reducing Plaque and Gingivitis
The objective of this study is to evaluate the clinical efficacy of a new toothpaste containing stannous fluoride (SnF) as compared to Colgate Fluoride Toothpaste in reducing gingivitis and dental plaque.
- Trial name
- NCT03852056
- Testing
- MFP Fluoride toothpaste, Stannous fluoride toothpaste
- Where
- China
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Plaque, Dental
Arginine Plaque Metabolism Pilot Clinical Study
Proof of concept clinical study to measure plaque metabolism and the prebiotic efficacy of arginine-containing toothpaste.
- Trial name
- NCT06954779
- Testing
- Colgate Cavity Protection, TOM's Superior Sensitivity Relief Toothpaste
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Periodontal Health, Dental Plaque Accumulation
Effects of Probiotics on Oral Health
Some probiotics have been shown to have preventive effects on infectious diseases and allergies. Because their long-term enhancement of the immune responses of children, they have been recommended for infants in some countries.
- Trial name
- NCT02444182
- Testing
- Probiotics
- Where
- Kuwait
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Kuwait University
Dental Caries
On Probiotic, Dental Caries, and Orthodontic Patients
To investigate the short term effect of probiotic oil on plaque acidogenicity among orthodontic patients. Shortage on testing the effect of probiotic on Orthodontic patients can be seen on litterateurs making a gap of whether is…
- Trial name
- NCT04593017
- Testing
- Active Probiotic
- Where
- Sweden
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Göteborg University