Clinical trials: Tooth Wear
Dentin Hypersensitivity
Ca-hydroxyapatite, Fluoroapatite, and Mg-Zn-hydroxyapatite for Dentin Hypersensitivity Management
This will be a double-blind, randomized, three-arm parallel groups study of the effect of toothpastes containing Ca-hydroxyapatite (HAP), Mg-Zn-hydroxyapatite (Zn-Mg-HAP), or fluoroapatite (FAP).
- Trial name
- NCT04896294
- Testing
- Hygienic procedure (toothbrushing using HAP-containing toothpaste), Hygienic procedure (toothbrushing using Zn Mg HAP-containing), Hygienic procedure (toothbrushing using FAP-containing toothpaste)
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Dental Caries in Children, Tooth Erosion
3D Scanning as an Advanced Tool for Identifying Tooth Lesions in Children
This study focuses on assessing dental caries, erosive tooth wear, and fluorosis in primary teeth using a 3D intraoral digital scanner.
- Conditions
- Dental Caries in Children, Tooth Erosion, Fluorosis, Dental, Dental Caries
- Trial name
- NCT06829550
- Testing
- indirect- 3D digital scanning
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Indiana University
Tooth Wear, Dental Restoration Failure
Full Occlusal Rehabilitation for Patients With Severe Tooth Wear Using Indirect Composite Restorations
LAVA Ultimate composite restorations will be used as restorative material to reconstruct severely worn dentitions.
- Conditions
- Tooth Wear, Dental Restoration Failure, Dental Restoration Wear
- Trial name
- NTWP (NCT02957734)
- Testing
- Rehabilitation of severely worn dentitions
- Where
- Netherlands
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Tooth Wear, Reflux Acid
7 Year Follow up Analysis on the Speed of Progression of Tooth Wear Using 3D Subtraction
Prospective observational study with 7-year follow up. 55 patients are included with moderate to severe tooth wear, whereby through informed consent the decision was taking to monitor the patients.
- Conditions
- Tooth Wear, Reflux Acid, Bruxism
- Trial name
- NCT04790110
- Where
- Netherlands
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Oral Diseases
Carnosine Supplementation on Quantity/Quality of Oral Salivae.
The aim of this study is to elucidate the mutual relationship between salivae characteristics and oral microbiome and to compare them with common oral disease; furthermore, by using specific bioinformatic tools to analyse the…
- Trial name
- PHoral (NCT04295525)
- Testing
- 400 mg mucoadhesive oral tablet
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Milan
Obesity, Oral Diseases
Obesity and Oral Diseases in Adult Patients
Overweight and obesity are among the major chronic disorders of the 21st century and one of the fastest growing health problems worldwide.
- Conditions
- Obesity, Oral Diseases, Periodontitis, Dental Caries
- Trial name
- ObOd (NCT04602572)
- Testing
- Lifestyle course., Bariatric surgery.
- Volunteers
- 400 people
- Sponsor
- University of Bergen
Dental Wear
Tooth Wear:m Tooth Wear : Diagnosis- Treatment Decision
Tooth wear is a physiological process occurring from normal functioning of the dentition throughout lifetime.
- Trial name
- NCT03540264
- Testing
- Clearfil Majesty TM, Vita-Enamic®
- Where
- Belgium
- Volunteers
- 52 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Enamel and Ceramics Wear
Wear Characteristics and Clinical Performance of Lithium Silicate Versus Monolithic Zirconia Crowns.
The aim of the present study is to evaluate the wear characteristics and clinical performance of lithium silicate crowns in comparison to monolithic zirconia crowns.
- Trial name
- NCT03530020
- Testing
- monolithic zirconia crowns, lithium silicate crowns
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Prevention of Mother-to-child Transmission of HIV
Retention of Women in the PMTCT (Prevention of Mother-to-child Transmission of HIV)
EXECUTIVE SUMMARY RESEARCH QUESTION TO BE ADDRESSED BY THIS PROPOSAL What are the factors associated with retention-in-care of women enrolled in the eMTCT Option B+ program at eMTCT (elimination of mother-to-child transmission of…
- Trial name
- NCT03213223
- Where
- Zimbabwe
- Volunteers
- 468 people, healthy volunteers welcome
- Sponsor
- University of Zimbabwe
Wear, Tooth, Wear, Occlusal
Wear of Enamel Antagonist to ZLS Crowns
The aim of this study is to evaluate the antagonist enamel wear of two processing options of Celtra duo crowns (polished and glaze fired) restoring posterior teeth in comparison with sound enamel wear at baseline and 6 months
- Trial name
- zls (NCT04914962)
- Testing
- glazed zirconium lithium silicate, polished zirconium lithium silicate
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Erosion of Teeth, Unspecified
Prophylactic Effect of a CANDIDA Mouthwash, Containing the Curolox™ Peptide
In vitro results showed a protective effect against acids for the mouthwash containing Curolox™ peptide. The goal of this in situ study is to detect the Curolox™ peptide under natural oral conditions on the tooth surface and to…
- Trial name
- NCT02308436
- Testing
- Candida Mouthwash with Curolox™ Peptide
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mibelle AG
Gastroesophageal Reflux Disease, Tooth Wear
Relationship Between Gastroesophageal Reflux Disease and Dental Erosion
This study aimed to investigate the relationship between gastroesophageal reflux disease (GERD) and dental erosion and the alterations in oral tissues. This was a case-control study.
- Trial name
- NCT04595500
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Orthodontic Tooth Movement
Clinical Trial to Assess the Efficacy of Reducing the Aligners' Wear Protocol
The hypothesis of this project is that replacing the current 7-day wear protocol with a 3-day wear protocol, while integrating less tooth movement per aligner (reduce the amount of activation per aligner) may produce more…
- Trial name
- NCT05905224
- Testing
- Invisalign 7-day wear protocol, Invisalign 3-day wear protocol
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Florida
Transdiagnostic Psychopathology, Attrition
Digital Rewards and Retention in a M-health App
Attrition and user engagement are two challenges that eHealth interventions struggle with. Attempts to address this have been previously made through gamification, instructional design and using different types of incentives.
- Conditions
- Transdiagnostic Psychopathology, Attrition, Engagement, Depression, Anxiety
- Trial name
- DIGITALRCT (NCT06883773)
- Testing
- Multipurpose Online Tool, No intervention
- Where
- Romania
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- University of Bucharest
Dental Wear
Wear Measurement of Opposing Enamel to Milled Resin Matrix Ceramic Versus Bulk Fill Resin Composite After 2 Years
This clinical trial conducted to measure the amount of wear of opposing enamel to indirect milled resin matrix ceramic versus direct bulk fill resin composite intraorally using Digital Scanner after two years of using
- Trial name
- NCT06807125
- Testing
- Resin matrix ceramic block
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Gingival Inflammation
Toothbrush Wear and Its Effect on Subgingival Inflammation Using Two Different Brushing Techniques
Toothbrush plaque removal, along with interproximal flossing, helps to maintain the oral cavity free from periodontal diseases and dental caries.
- Trial name
- NCT03158350
- Testing
- Instructed Brushing Method
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Tufts University
Tooth Erosion
Evaluation of a Test Mouthwash and Dentifrice Regimen in an In-situ Model of Dental Erosion
An in situ model will be used to evaluate and compare enamel remineralization of bovine enamel specimens.
- Trial name
- NCT01128972
- Testing
- Sodium fluoride, Sodium monoflurophosphate, Sterile water
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Non-carious Cervical Lesions
Evaluation of Double Layer Application Using a Universal Adhesive in the Quality of Cervical Lesions Restorations
The aim of this study will be to evaluate the effect of a double layer application of a universal adhesive system used as etch-and-rinse application mode in non-carious cervical lesions (NCCLs), on the 6- and 12-months clinical…
- Trial name
- NCT06474494
- Testing
- Application of one layer, Application of double layer, Etch-and-rinse application mode
- Where
- Chile
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Tooth Erosion
An Erosion Study to Investigate the Efficacy of an Experimental Dentifrice to Remineralize Enamel
The purpose of this study is to investigate the ability of an experimental dentifrice containing 1150 parts per million (ppm) fluoride to remineralize acid-softened dental enamel and help prevent further demineralization compared…
- Trial name
- NCT06242444
- Testing
- Experimental Dentifrice, Reference Dentifrice
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- HALEON
Sjögren Syndrome
Dental and Periodontal Status of Patients With Sjögren's Syndrome.
Sjögren's syndrome (SS) is a rare chronic systemic autoimmune disease characterized by destruction of the exocrine glands, including the salivary glands.The lack of saliva exposes the patient to dental caries, and dental wear…
- Trial name
- CB-SJO (NCT04848870)
- Testing
- Salivary samples
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris