Clinical trials: Topical Anaesthesia
Anesthesia
The Effect of Er,Cr:YSGG Laser-assisted Topical Anesthetic on Oral Mucosal Anesthesia
This study tests whether using an Er,Cr:YSGG laser before applying numbing gel (lidocaine) can help reduce pain during dental procedures compared to traditional methods.
- Trial name
- NCT07169032
- Testing
- Er,Cr:YSGG laser irradiation, Lidocaine, Vaseline
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Li Zhen Zhong
Cataract Surgery Anesthesia
Topical Jelly and Intracameral Anesthesia Versus Subtenon Anesthesia, in Cataract Surgery
The options for anesthesia in cataract surgery described are: general, regional or local. The local strategy, it may be by periocular blocking(subtenon, peribulbar or retrobulbar), subconjunctival or topical.
- Trial name
- NCT01344252
- Testing
- Lidocaine
- Where
- 2 sites in Argentina
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hospital Italiano de Buenos Aires
Cataract Surgery
Music Listening for Cataract Surgery
The purpose of the study is to assess the effect of music therapy on anxiety and hypertension during cataract surgery procedures performed under topical anaesthesia.
- Trial name
- MUSICATOP (NCT02892825)
- Testing
- Music, No Music
- Where
- France
- Volunteers
- 313 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Equally of Delivery Systems of Local Anesthesia in Bronchoscopy
Topical Anesthesia / Bronchoscopy
The primary aim of this study is to compare a simplified single-use product (LMA® MAD Nasal™ Intranasal Mucosal Atomization Device, Teleflex medical, Kernen Germany) for topical nasopharyngeal anesthesia in comparison to a…
- Trial name
- TNA (NCT02237651)
- Testing
- topical anesthesia multi-use device, topical anesthesia Intranasal Mucosal Atomization
- Where
- Germany
- Volunteers
- 252 people
- Sponsor
- Hannover Medical School
Pain
Jet Injection of 1% Buffered Lidocaine Versus Topical ELA-Max for Anesthesia Prior to Intravenous (IV) Catheterization in Children
This trial is a comparison of the anesthetic effectiveness of J-Tip needle-free jet injection of 1% buffered lidocaine to the anesthetic effectiveness of topical 4% ELA-Max for peripheral intravenous catheter (PIV) insertion.
- Trial name
- NCT00444756
- Testing
- J-tip jet injection of 1% buffered lidocaine
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Norton Healthcare
Glaucoma
Comparison of Topical Anesthesia and Analgosedation in Micropulse Transscleral Glaucoma Treatment
Topical Anesthesia will be compared to Analgosedation for pain control in Micropulse Transscleral Laser Treatment for Glaucoma (MP-TLT).
- Trial name
- TAPMP3 (NCT04448080)
- Testing
- Micropulse Transscleral Laser Therapy for Glaucoma (MP-TLT)
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- University of Zurich
Sedation
Patient-controlled Sedation With Propofol During Cataract Surgery Under Topical Anesthesia
Controversies exist about the use of propofol in sedation of patients for cataract surgery. This prospective randomised double-blind study evaluates the efficacy of patient-controlled sedation compared with placebo using the same…
- Trial name
- CATARSIS (NCT02771912)
- Testing
- Propofol
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Throat Disorder
Pretreatment to Reduce Pain and Discomfort During Fiberoptic Nasal Pharyngoscopy and Laryngoscopy
Fiberoptic laryngoscopy (FOL) is one of the most common procedure done in an Ear Nose Throat (ENT) clinic. Topical anesthesia or decongestant or both have been used to improve patient comfort level during the procedure.
- Trial name
- NCT03620513
- Testing
- Decongestant (oxymetazoline 0.05%), Anesthesia (Lidocaine 15%), Decongestants and Anesthesia (oxymetazoline and lidocaine)
- Where
- Nepal
- Volunteers
- 160 people
- Sponsor
- Lumbini Medical College
Drug Usage
Intubating Conditions During Propofol-remifentanil Anesthesia With Topical Lidocaine
When not using neuromuscular blocking agent, even at optimal dosage, target-controlled infusion (TCI) of propofol and remifentanil occasionally produce unsatisfactory intubating conditions.
- Trial name
- NCT01489683
- Testing
- lidocaine, normal saline
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Ajou University School of Medicine
Dental Anxiety, Children
Effects of Topical Anesthetics on Pain and Anxiety in Children
Dental anxiety and pain associated with local anesthetic injections are among the most common barriers to successful dental treatment in children.
- Trial name
- NCT07733622
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Injection Site Pain, Pain
Comparing Pre-Anesthetic Approaches in Dentistry
The main purpose of this study is to find out which pre-treatment method works best to reduce pain from dental anesthesia injections in adult patients.
- Trial name
- NCT07703553
- Testing
- 10% lidocaine spray, Ice Pen (Cryotherapy)
- Where
- Turkey (Türkiye)
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Harran University
Retinal Disease, Diabetic Retinopathy
Pain During Pars Plana Vitrectomy With Sub-tenon Anesthesia
Vitreoretinal surgery has evolved to less invasive procedures, and it is used to treat a wide range of diseases. So anesthesia for vitreoretinal procedures has evolved, promoting adequate analgesia while reducing risks to the…
- Conditions
- Retinal Disease, Diabetic Retinopathy, Maculopathy
- Trial name
- NCT03902925
- Testing
- Topical lidocaine 2% jelly plus sub-tenon ropivacaine 10% injection, Peribulbar injection
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- University of Sao Paulo
Postoperative Pain, Topical Anaesthesia
Topical Lidocaine After Arthroscopy on Knee
More than half of the patients suffer from intensive pain 1-2 days after arthroscopy in the knee. Walking function and physical activities are affected by this intensive pain although local anaesthetic is given in the joint and…
- Trial name
- NCT02460627
- Testing
- Lidocaine adhesive tape, Adhesive tape
- Where
- Denmark
- Volunteers
- 180 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Oral Anxiolytic, Phacoemulsification
Anxiety and Surgery Satisfaction for Cataract Patient With Different State Anxiety
This study aims to explore the effects of anxiety traits on pain, anxiety, and anesthesia satisfaction in patients undergoing cataract surgery under topical anesthesia.
- Conditions
- Oral Anxiolytic, Phacoemulsification, Cataract Surgery, Satisfaction Survey
- Trial name
- NCT06826417
- Testing
- Xanax
- Where
- Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Mucositis
Local Anesthetic Treatment of Oral Pain in Patients With Mucositis
Oral mucositis is a damage to the mucosa of the oral cavity and pharynx. It is a serious and painful adverse effect caused by the radio therapy and/or chemo therapy patients with head and neck cancer receive.
- Trial name
- NCT02252926
- Testing
- Bupivacaine, Standard treatment (lidocaine viscous solution, morphine, paracetamol, NSAID, gabapentin)
- Where
- 2 sites in Denmark
- Volunteers
- 70 people
- Sponsor
- Hvidovre University Hospital
Labor, Induced
Topical Anesthesia During Catheter Insertion for Cervical Ripening (TOLERANCE)
The goal of this RCT is to learn if application of topical anesthetic cream to the perineum and posterior wall of vagina prior to balloon catheter insertion as part of labor induction will reduce pain levels experienced by…
- Trial name
- TOLERANCE (NCT07288021)
- Testing
- Topical Analgesia with Lidocaine-Prilocaine cream
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Bnai Zion Medical Center
Forehead Rhytides, Forehead Wrinkles
Botulinum Toxin Type A Injection After Topical Anesthesia Versus Petrolatum Ointment
The purpose of this study is to determine whether there is a difference in clinical effect, duration of effect, level of discomfort and patient satisfaction in patients receiving topical anesthesia on one side of the forehead and…
- Trial name
- NCT03799484
- Testing
- Botulinum toxin type A, 2.5% lidocaine/2.5% prilocaine, petrolatum ointment
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Bronchoscopy, Anesthesia, Local
5 Versus 10 Sprays of Lignocaine for Pharyngeal Anaesthesia During Bronchoscopy
Flexible bronchoscopy is one of the most widely performed procedures for diagnosis of various bronchopulmonary diseases. Most patients tolerate the procedure well although cough is often reported as a distressing symptom.
- Trial name
- NCT03869528
- Testing
- 5 sprays of 10% lignocaine, 10 sprays of 10% lignocaine
- Where
- 2 sites in India
- Volunteers
- 300 people
- Sponsor
- All India Institute of Medical Sciences
Pain
Reduction of Topical Anesthetic Time for Subcutaneous Port Access Using Ultrasound
Children ages 3-17 who are undergoing port access receive both standard care, topical medicine for numbing (LMX4), and the study intervention which utilizes ultrasound to speed the onset of LMX4 from 30 minutes to 5 minutes.
- Trial name
- NCT00126919
- Testing
- SonoPrep
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Connecticut Children's Medical Center
Topical Anesthesia
Impact of Topical Pharyngeal Anesthetics on Discharge of the Patients When Used in Conjunction With Propofol Sedation in Routine EGD's
To find out if the administration of the local pharyngeal anesthetic, lidocaine, in conjunction with Propofol during elective Esophagogastroduodenoscopy (EGD) is useful, safe and impacts the time of discharge of patient compared…
- Trial name
- NCT02507440
- Testing
- Lidocaine, Propofol
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Bassett Healthcare