Clinical trials: Total Blood Loss
Intraoperative Bleeding, Post-operative Bleeding
Study to Compare the Addition of Floseal to Our Standard of Care to Control Post Operative Bleeding in TKR
The purpose of this study is to compare Floseal to our standard of care (SOC) to decrease intraoperative and immediate post-operative bleeding.
- Trial name
- NCT01891461
- Testing
- Floseal
- Where
- Canada
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Hematoma, Arthroplasty Complications
The Effect of Releasing the Tourniquet in Total Knee Replacement Before Closure on the Blood Loss , Joint Effusion , Hematoma Formation and Wound Complication
The study , observe the effect of releasing the Tourniquet in total knee replacement surgery before closure in comparison with releasing it after wound closure The effect was assessed by Hb drop post operative and Hematoma…
- Trial name
- NCT04810000
- Testing
- tourniquet
- Where
- Jordan
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Yazan Saleh Rajab Hammad
Postoperative Bleeding
Tranexamic Acid Use on Pain, Mobility and Bleeding Following Total Hip and Total Knee Arthroplasty
Tranexamic acid (TXA) is an anti-fibrinolytic agent developed in the 1960s that has been safely used to reduce blood loss, transfusion rates and bleeding-associated mortality in trauma, obstetrics and orthopedic surgery…
- Trial name
- TXA (NCT06208267)
- Testing
- Tranexamic acid
- Where
- Canada
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- St. Mary's Research Center, Canada
Hemorrhage, Vascular Injury
A Transparent Elasticized Adhesive Occlusive Compression Bandage for Use as an Arterial Tourniquet
This cross-over study of twenty five (anticipated) healthy human subjects will utilize two active control devices, and two different widths of the investigational device.
- Trial name
- NCT02592655
- Testing
- Pneumatic Tourniquet, One Windlass Tourniquet, Two Windlass Tourniquets
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Marcus Migura
Infection of Total Knee Joint Prosthesis, Aseptic Loosening of Prosthetic Joint
Surgical / Economic Effect of the Aquamantys System in Blood Management for Aseptic and Septic Revision TKA
To assess the surgical and economic effectiveness of the Aquamantys System in managing intra- and post-operative blood loss, and reducing transfusion needs in patients undergoing both aseptic and septic revision total knee…
- Trial name
- NCT02266407
- Testing
- Aquamantys System
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medtronic Surgical Technologies
Total Blood Loss, Arthropathy of Knee Joint
Kaolin-based Hemostatic Gauze in Total Knee Arthroplasty
This study is to conduct a prospective randomized controlled trial to investigate the blood-conservation effect of combination of intravenous TXA and QCG in a primary TKA procedure.
- Trial name
- NCT05504577
- Testing
- Tranexamic acid injection, apply the QCG, apply surgical gauze
- Where
- Taiwan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Postoperative Hemorrhage
Efficacy of Intra-auricular Tranexamic Acid in Total Knee Arthroplasty
Tranexamic acid an antifibrinolytic that develops its anti-haemorrhagic action by inhibiting fibrinolytic activities of plasmin and many studies confirms its effectiveness in decreasing blood loss.
- Trial name
- NCT04085575
- Testing
- Acide Tranexamique
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Montauban
Blood Loss, Surgical
Arista Hemostatic Powder for Total Knee Post Operative Outcomes Study
To examine in Arista hemostatic powder results in less post-total knee arthroplasty blood loss, hematoma formation, and improved range of motion when compared to patients who did not receive the product.
- Trial name
- NCT05522153
- Testing
- Arista
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Virtua Health, Inc.
Surgical Blood Loss, Burns
Measurement of Blood Volume Loss During Burn Surgery
Burn surgery is associated with significant reductions in hematocrit. However, it is unclear whether these reductions are the result of hemodilution from non-red cell containing intraoperative transfusions or from loss of red…
- Trial name
- NCT03340116
- Testing
- Burn surgery, Measurement of RBC volume, plasma volume, and total blood volume using Daxor BVA-100
- Volunteers
- healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Infection, Bleeding
Effects of Microcrystalline Titanium Dioxide With Covalently Linked Monovalent Silver Ions on Complications After Total Hysterectomy ( ISTIAB-0)
Total hysterectomy is one of the most performed surgical procedures in the world and it is associated with post-operative complications.
- Conditions
- Infection, Bleeding, Complication, Postoperative
- Trial name
- ISTIAB-0 (NCT03791294)
- Testing
- TIAB: microcrystalline titanium dioxide with covalently linked monovalent silver ions
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Università degli Studi dell'Insubria
Rhinosinusitis Chronic, Sinus Cancer
TIVA vs TXA in Sinus Surgery to Evaluate Operative Blood Loss and Surgical Field Quality
The goal of this interventional study is to compare the efficacy (surgical field quality and intra-operative blood loss) or cost of TIVA alone to general inhalational anesthetics with intravenous TXA in patient participants who…
- Conditions
- Rhinosinusitis Chronic, Sinus Cancer, Sinus Polyp, Encephalocele
- Trial name
- NCT05639686
- Testing
- Tranexamic acid injection, Total Intravenous Anesthesia, Inhalational isoflurane
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Our Lady of the Lake Hospital
Abdominal Hysterectomy
Intravenous Ascorbic Acid Administration in Hysterectomy
vitamin C or ascorbic acid has known role in tissue repair. due to it's properties(water_soluble), vitamin c is not stored in the body and when depleted, the bleeding tendency will increase due to dysfunctional connective tissues…
- Trial name
- NCT03965637
- Testing
- vitamin C
- Where
- Iran
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University
Blood Loss
Intraoperative Bleeding During Endoscopic Sinus Surgery
The purpose of this study is to compare the blood loss during sinus surgery looking at two different types of anesthesia: either intravenous anesthesia with propofol or inhalational anesthesia with sevoflurane.
- Trial name
- NCT01014728
- Testing
- propofol, sevoflurane
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Post Operative Blood Loss
Role of Topical Tranexamic Acid in Total Hip Arthroplasty
Total hip arthroplasty (THA) is a procedure associated with perioperative blood loss, requiring blood transfusions in some patients.
- Trial name
- TXA (NCT01866943)
- Testing
- Tranexamic Acid, Normal Saline Solution
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Knee Osteoarthritis
Comparison of Floseal® and Tranexamic Acid on Bleeding Control After Total Knee Arthroplasty
The total knee arthroplasty (TKA) is a well established option for the treatment of osteoarthritis in this joint. Nevertheless, there are still some concerns related to the peri-operative management of elderly patients…
- Trial name
- NCT02152917
- Testing
- Tranexamic acid, Floseal®
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Degenerative Joint Disease, Osteoarthritis
Epsilon Aminocaproic Acid (EACA) for the Reduction of Blood Loss in Total Hip Arthroplasty (THA)
You are being asked to take part in this research study because you are scheduled to have total hip replacement (arthroplasty) surgery.
- Trial name
- NCT01391182
- Testing
- EACA
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Infection, Bleeding
Effects of Microcrystalline Titanium Dioxide With Covalently Linked Monovalent Silver Ions on Complications After Total Hysterectomy
Total hysterectomy is one of the most performed surgical procedures in the world and it is associated with post-operative complications.
- Conditions
- Infection, Bleeding, Complication, Postoperative
- Trial name
- ISTIAB-1 (NCT03789799)
- Testing
- TIAB: microcrystalline titanium dioxide with covalently linked monovalent silver ions
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Università degli Studi dell'Insubria
Osteoarthritis
Study Comparing Peri-articular Injection of Bupivacaine With and Without Epinephrine
This study involves research. The purpose of this research is to formally investigate the hemostatic efficacy of epinephrine to minimize blood loss after total joint arthroplasty.
- Trial name
- NCT00737139
- Testing
- Peri-articular injection of marcaine/epinephrine, Peri-articular injection of marcaine alone
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Blood Loss, Anatomic Total Shoulder Arthroplasty
Investigation of Intravenous Tranexamic Acid With Anatomic and Reverse Total Shoulder Arthroplasty
To compare intravenous Tranexamic Acid (TXA) versus normal saline placebo to determine whether or not TXA administration reduces blood loss, decrease in hemoglobin, and rate of transfusions following anatomic and reverse total…
- Conditions
- Blood Loss, Anatomic Total Shoulder Arthroplasty, Reverse Total Shoulder Arthroplasty, Transfusion
- Trial name
- NCT02569658
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Osteoarthritis, Knee
Topical Tranexamic Acid and Floseal® in Total Knee Arthroplasty
Our purpose of this study is to conduct a prospective randomized controlled trial to investigate the blood-conservation effect of this two topical hemostatic agents in primary TKA procedures in patients with a risk of…
- Trial name
- NCT02865174
- Testing
- Topical tranexamic acid, Floseal®, Enoxaparin
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital