Clinical trials: Total Hip Replacement
Total Knee Replacement, Total Hip Replacement
Meloxicam for Pain Management After Total Joint Arthroplasty (TJA)
The purpose of this project is to determine if a change in patient reported pain, nausea and vomiting after total knee and hip arthroplasty could be observed with the substitution of Intravenous meloxicam for ketorolac in the…
- Trial name
- NCT05291598
- Testing
- IV meloxicam, Ketorolac
- Where
- United States
- Volunteers
- 223 people
- Sponsor
- University of Miami
Arthritis
A Prospective Study to Evaluate the Effectiveness of a Haemostatic Agent in Primary Unilateral Total Hip Arthroplasty
This is a prospective, randomized, controlled, single-center study to assess the effectiveness of Vitagel, a surgical hemostat, in primary unilateral total hip arthroplasty (THA).
- Trial name
- NCT01285024
- Testing
- Vitagel
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- The Cleveland Clinic
Osteoarthritis
Analgesia After Total Hip Arthroplasty: Peri-Articular Injection Versus Epidural Patient Controlled Analgesia (PCA)
The best way to provide analgesia after total hip arthroplasty is hotly debated. There are two protocols in use at Hospital for Special Surgery(HSS).
- Trial name
- PAI Hip (NCT01658072)
- Testing
- Peri-Articular Injection, Epidural Patient Controlled Analgesia (Epidural PCA)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Hospital for Special Surgery, New York
Avascular Necrosis, Osteoarthritis
Continuum™ Metal Bearing System in Total Hip Arthroplasty
The study is a multi-center, prospective, non-controlled, consecutive cohort post market surveillance study. The objective of this study is to obtain survival and outcome data on the Continuum Metal Bearing System in primary…
- Conditions
- Avascular Necrosis, Osteoarthritis, Inflammatory Arthritis, Post-traumatic; Arthrosis
- Trial name
- NCT03382652
- Testing
- Metal-on-Metal Articulation
- Where
- 3 sites in United States, Finland
- Volunteers
- 83 people
- Sponsor
- Zimmer Biomet
Total Hip Replacement System
Ceramic on Metal Total Hip Replacement System Multi-Center,Investigational Device Exemption Clinical Trial
The purpose of this study is to demonstrate non-inferiority of the Ceramic on Metal Total Hip when compared to a TRANSCEND® historical control group of patients with primary total hip replacement.
- Trial name
- COM (NCT00820443)
- Testing
- Ceramic on metal prosthesis
- Where
- United States
- Volunteers
- 253 people
- Sponsor
- MicroPort Orthopedics Inc.
Osteoarthritis, Arthritis
Study Comparing Marathon Polyethylene and Enduron Polyethylene Acetabular Liners Used in Total Hip Arthroplasty
The purpose of the study is to determine whether crosslinked Marathon and standard Enduron polyethylene liners show differences in bone loss around the hip implant.
- Conditions
- Osteoarthritis, Arthritis, Joint Diseases, Musculoskeletal Diseases
- Trial name
- NCT01121146
- Testing
- Total Hip Replacement
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Anderson Orthopaedic Research Institute
Degenerative Hip Joint Disease, Rheumatoid Arthritis (RA)
Study to Evaluate the Safety and Efficacy of OR3O™ Dual Mobility System vs. Conventional Single Bearing Design Total Hip System
The purpose of this study is to compare OR3O™ Dual Mobility System to a conventional, single-bearing design Total Hip System in subjects who undergo Primary THA.
- Conditions
- Degenerative Hip Joint Disease, Rheumatoid Arthritis (RA), Femoral Neck Fractures, Avascular Necrosis of Femoral Head
- Trial name
- OR3O (NCT04941729)
- Testing
- OR3O™ - Dual Mobility System, Conventional
- Where
- 4 sites in China
- Volunteers
- 24 people
- Sponsor
- Smith & Nephew Medical (Shanghai) Ltd
Osteoarthritis, Hip
Whole Blood Metal Ion Concentrations in Metal-on-metal Total Hip Arthroplasty and Hip Resurfacing
The investigators aimed to investigate the possible differences in metal ion concentrations in patients following one of two types of metal-on-metal articulating hip prosthesis regarding chromium and cobalt concentration…
- Trial name
- NCT04585022
- Testing
- Magnum, Zimmer Biomet, Warsaw, IN, Recap, Zimmer Biomet, Warsaw, IN
- Volunteers
- 75 people
- Sponsor
- Hvidovre University Hospital
Arthritis of Hip
Fascia Iliaca Blocks for Pain Control After Total Hip Arthroplasty
The fascia iliaca compartment block (FICB) is a regional block that anesthetizes the femoral, obturator, and lateral femoral cutaneous nerves around the hip.
- Trial name
- NCT03375112
- Testing
- Fascia iliaca compartment block, Bupivacaine
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- Henry Ford Health System
Arthroplasty, Replacement, Hip, Exercise Therapy
Walking Skill Training Program Effects in Patients With Total Hip Arthroplasty
Rehabilitation plays an important part after total hip arthroplasty. In this common practice few studies have been performed on this issue. The aims of this study were: 1.
- Trial name
- NCT00808483
- Testing
- Walking skill training program
- Where
- Norway
- Volunteers
- 68 people
- Sponsor
- University of Oslo
Total Hip Replacement
Rehabilitation of Patients After THR - Based on Patients´Selfrated Health
Objective: The investigators hypothesized that all areas of health status after total hip replacement could be improved in patients aged over 65 years and over by using telephone support and counselling 2 and 10 weeks after…
- Trial name
- Rehab-THR (NCT02644096)
- Testing
- counselling and support after discharge from hospital
- Volunteers
- 175 people
- Sponsor
- University of Aarhus
Total Hip Arthroplasty
A Hemodynamic Comparison of Stationary and Portable Pneumatic Compression Devices
We are comparing two pneumatic compression devices, VenaFlow (stationary) and MCS (portable) in both the supine an standing position.
- Trial name
- NCT02345642
- Testing
- ActiveCare+SFT Supine, VenaFlow Elite Supine, ActiveCare+SFT Standing
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Total Hip Replacement
Evaluation of X-ray, Acetabular Guides and CT in THR
Total hip replacement is one of the most successful surgical procedures of modern times, with over 80,000 performed each year in the UK.
- Trial name
- EXACT (NCT03072706)
- Testing
- Corin OPS™, 2D X-ray templating technology
- Where
- United Kingdom
- Volunteers
- 54 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Osteoarthritis, Arthroplasty
Psoas Compartment Block Versus Periarticular Local Anesthetic for Total Hip Arthroplasty
The primary objective of this study is to examine whether there is a difference in the level of resting pain following total hip arthroplasty with an anterior approach with use of a psoas compartment block versus a local…
- Trial name
- NCT02658149
- Testing
- Ropivacaine with NaCl, Epinephrine, Morphine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Corewell Health East
Hip Osteoarthritis, Noninflammatory Degenerative Joint Disease
Randomized Controlled RSA Study Comparing the Taperloc Complete Versus the Taperloc Complete Microplasty.
This is a single center, prospective, randomized controlled study. The primary objective of this study is to measure migration over two years with RSA.
- Conditions
- Hip Osteoarthritis, Noninflammatory Degenerative Joint Disease, Avascular Necrosis, Correction of Functional Deformity
- Trial name
- NCT03409666
- Testing
- Taperloc Complete Microplasty stem, Taperloc Complete Reduced Distal stem
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Zimmer Biomet
Dysplasia; Hip, Prosthesis Survival
Long-term Outcomes of Conical Tapered Stems in Cementless Total Hip Arthroplasty Due to Congenital Hip Pathologies
A retrospective consecutive population of patients treated with conical tapered stems in cementless total hip arthroplasty for osteoarthritis due to congenital hip pathologies will be selected.
- Trial name
- RetroCone (NCT04748458)
- Testing
- Conical tapered stem
- Where
- Italy
- Volunteers
- 85 people
- Sponsor
- Istituto Ortopedico Rizzoli
Venous Thromboembolism, Arthroplasty, Replacement
Pradaxa (Dabigatran Etexilate) VTE Prevention After Elective Total Hip or Knee Replacement Surgery
an open, prospective, observational study to collect data on safety (major bleeding events) and efficacy (symptomatic venous thromboembolism(VTE)) of a switch from Enoxaparin to dabigatran etexilate in patients with total knee…
- Trial name
- NCT01153698
- Testing
- dabigatran
- Where
- 7 sites in Austria
- Volunteers
- 167 people
- Sponsor
- Boehringer Ingelheim
Perioperative Hypothermia
Prospective Trial of the Effect of Preoperative Forced-air Warming on Perioperative Body Temperature Following Neuraxial Anesthesia in Total Hip Arthroplasty Patients
The purpose of this study is to determine if placement of a forced-air warming device prior to institution of regional anesthesia improves perioperative temperature control in patients undergoing total hip arthroplasty.
- Trial name
- NCT01626690
- Testing
- Bair-Paws Warming Device, Bair-Hugger Warming Device
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Wisconsin, Madison
Prevention, Venous Thromboembolism
A Study of DU-176b, Prevention of Venous Thromboembolism in Patients After Total Hip Arthroplasty
The objective of this study is to assess the efficacy and safety of DU-176b compared with enoxaparin sodium for the prevention of venous thromboembolism in patients after elective total hip arthroplasty.
- Trial name
- NCT01181167
- Testing
- edoxaban, enoxaparin sodium
- Where
- 2 sites in Japan
- Volunteers
- 610 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Blood Loss
Evaluating the Use of Tranexamic Acid (TXA) in Total Joint Arthroplasty
This research study aims to study the use of tranexamic acid (TXA) in total joint replacement (arthroplasty) of the hip (THR) and knee (TKR).
- Trial name
- NCT03825939
- Testing
- Intravenous Tranexamic Acid
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- NYU Langone Health