Clinical trials: Total Hip Replacement Surgery
Deep Vein Thrombosis, Pulmonary Embolism
Venous Blood Flow Velocity: Electrical Foot Stimulation Compared to Intermittent Pneumatic Compression of the Foot
Electrical stimulation of the foot can increase blood flow out of the leg. This increased blood flow can prevent blood clots from forming in the leg veins.
- Trial name
- NCT00114608
- Testing
- The Focus™ Neuromuscular Stimulation System
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University at Buffalo
Metallosis, Pain
Neurotoxicity and Cardiotoxicity in Total Joint Arthroplasty
The purpose of this research is to understand whether patients who previously had total hip or total knee replacement experience memory, thinking or heart problems.
- Conditions
- Metallosis, Pain, Total Hip Replacement, Total Knee Replacement
- Trial name
- NCT04166539
- Testing
- Questionnaires, Interviews, Blood draw
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Hip Pain
Metal Ion Levels in Stryker Trident II Tritanium System with Modular Dual Mobility (MDM) Liner, Ceramic Head, and SecurFit Advanced Stems
Metal Ions levels of cobalt, chromium, and titanium in 40 patients preoperatively and at least 1 year status post total hip replacement with the Trident II Tritatnium system using an MDM liner and ceramic head.
- Trial name
- NCT03433742
- Testing
- Blood levels drawn
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Pain, Postoperative
Effect of Unilateral Erector Spinae Plane Block Versus Intrathecal Morphine on Early Mobilization After Hip Replacement
Preoperative assessment: Patients who fulfill inclusion criteria will be evaluated by medical history, physical examination and clinical laboratory tests which are a complete blood picture (CBC), kidney function tests, liver…
- Trial name
- NCT06621849
- Testing
- erector spinae plane block, Morphine
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cairo University
Osteoarthritis
Does Optimal Control of Pre-operative Chronic and Acute Pain Predict Improved Function After Orthopedic Surgery?
Despite the development of new pain medications, the prevalence of persistent postoperative pain (for more than three to six months) remains alarmingly high.
- Trial name
- NCT00581685
- Testing
- Pregabalin, Celecoxib
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Hip Arthroplasty
Rehabilitation to Patients Over 65 Years Undergoing THA
Patients over 65 years do not have a self care ability the surgery benefits them. The aim of this study is development of a rehabilitation program based on patients' self-rated health. 1.
- Trial name
- NCT00226070
- Testing
- interview and advising, 3 follow up interviews and personal advising, interview SF-36 self rated health
- Where
- 6 sites in Denmark
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Osteoarthritis, Arthritis
Marathon and Enduron Polyethylene at Long-Term Follow-up
The purpose of the study is to determine whether crosslinked Marathon and standard Enduron polyethylene liners show differences in survivorship due to wear-related revisions at minimum 14-year follow-up and every 5 years after.
- Conditions
- Osteoarthritis, Arthritis, Joint Diseases, Musculoskeletal Diseases
- Trial name
- NCT02508428
- Testing
- Hip Replacement with crosslinked Marathon polyethylene, Hip Replacement with noncrosslinked Enduron polyethylene
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Anderson Orthopaedic Research Institute
Total Hip Arthroplasty, Hip Arthrosis
Tissue Sparing Surgery in Total Hip Arthroplasty
Rationale of the study is to evaluate through a prospective randomized controlled study if a modified direct superior posterolateral approach (sperimental approach) to the hip articulation which entirely spares i.e.
- Trial name
- NCT04358250
- Testing
- Direct Superior Approach, posterolateral approach
- Where
- 2 sites in Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Arthritis of Hip
Goal-directed vs Preemptive Tranexamic Acid Administration in Total Hip Arthroplasty
The present study is a multi-center randomized prospective placebo-controlled non-inferiority trial. The study's primary objective is to compare the amounts of postoperative bleeding using two different TXA administration…
- Trial name
- NCT05956769
- Testing
- Tranexamic Acid, thromboelastography
- Where
- 2 sites in South Korea
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Blood Loss, Surgical, Tranexamic Acid Adverse Reaction
TRANEXAMIC ACID IN PATIENTS UNDERGOING TOTAL HIP ARTHROPLASTY IN A BRAZILIAN REFERENCE ORTHOPEDIC CENTER: A RANDOMIZED CONTROLLED TRIAL
This study aims to analyze the efficacy of intravenous tranexamic acid (TXA) in patients undergoing total hip arthroplasty (THA).
- Conditions
- Blood Loss, Surgical, Tranexamic Acid Adverse Reaction, Hip Replacement
- Trial name
- NCT03019198
- Testing
- Tranexamic Acid Injectable Solution
- Where
- Brazil
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Traumatologia e Ortopedia
Frailty, Cognitive Impairment
Orthopedic Procedures and Postoperative Delirium in Older Adults in the Czech Republic
This multicenter, prospective, non-interventional observational study (ORTOPODCZ) investigates the association between preoperative cognitive impairment and postoperative delirium (POD) in older adults undergoing elective total…
- Conditions
- Frailty, Cognitive Impairment, Older Adults, Hip Arthroplasty
- Trial name
- ORTOPODCZ (NCT07432009)
- Where
- 7 sites in Czechia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Tomas Bata Hospital, Czech Republic
Arthroplasty, Replacement, Hip
Does Testosterone Therapy Improve Patient-Reported Outcomes in Age-Related Testosterone Deficient Patients Undergoing Total Hip Replacement: A Randomized-Controlled Trial
This randomized-controlled trial will study on the effect of testosterone therapy on patients undergoing total hip replacement. Subjects will be male patients > 50 years with testosterone deficiency undergoing total hip…
- Trial name
- NCT05722301
- Testing
- Testosterone Therapy, No Testosterone Therapy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- American Hip Institute
Tranexamic Acid, Blood Loss, Surgical
Intravenous vs. Topical Tranexamic Acid in Revision THA (VITALITY-X)
The objective of this study is to evaluate and compare the effects of intravenous and topical administration of tranexamic acid during revision hip arthroplasty on blood loss, allogenic blood transfusion rates, length of hospital…
- Conditions
- Tranexamic Acid, Blood Loss, Surgical, Arthroplasty, Replacement, Hip
- Trial name
- VITALITY-X (NCT02938962)
- Testing
- Tranexamic Acid
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Total Knee Replacement Surgery, Total Hip Replacement Surgery
Xperience™ vs Normal Saline Irrigation Solution for Decreasing Bioburden After Primary Total Hip and Knee Arthroplasty
The purpose of this study is to evaluate the effectiveness of Xperience, a no rinse antimicrobial solution, on joint infection rates in patients undergoing total hip (THA) and total knee (TKA) arthoplasty surgery.
- Trial name
- NCT05577936
- Testing
- XPERIENCE Advanced Surgical Irrigation, Standard of Care Irrigation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip
Sleep Patterns After Total Joint Replacement Surgery
The purpose of this study is to determine sleep patterns and sleep quality following total joint arthroplasty, in order to understand when patients should expect to return to baseline or improved sleep following total joint…
- Trial name
- NCT04896892
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Postoperative Cognitive Dysfunction
Postoperative Cognitive Dysfunction After Total Knee or Hip Replacement Surgery in Fast-track Set-up
The aim of this study is to quantify the incidence of postoperative cognitive dysfunction in the elderly patient (>60y) after total hip or knee replacement surgery.
- Trial name
- NCT01103752
- Testing
- no intervention, descriptive study
- Where
- Denmark
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Lene Krenk
Hip Replacement
Quadratus Lumborum Block Versus Fascia Iliaca Nerve Block for Patients Undergoing Total Hip Replacement
Investigators hypothesise that for patients undergoing elective total hip replacements, a single injection Transmuscular Quadratus Lumborum (TQL) block, when compared to a single injection Fascia Iliaca Block (FIB), will provide…
- Trial name
- NCT03551860
- Testing
- TQL, FIB
- Where
- Ireland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Adelaide and Meath Hospital, incorporating The National Children's Hospital
Rehabilitation, Analgesia
Observational Prospective Study of Opiate-free Anesthesia for Anterior Total Hip Replacement
Opioid-free anesthesia (ATO) is a multimodal anaesthesia combining different analgesic and anesthetic modalities thus excluding opiates as an intraoperative.
- Conditions
- Rehabilitation, Analgesia, Anesthesia
- Trial name
- ASOPHA (NCT04112277)
- Testing
- Cumulative morphine consumption
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hôpital Privé Sévigné
Erythema, Drainage
A Comparison of INSORB Staples With Metal Staples in Total Hip Replacement
The purpose of this study is to compare the use of INSORB absorbable staples with metal staples on surgical incision healing after total hip replacement.
- Conditions
- Erythema, Drainage, Bruising, Pain
- Trial name
- NCT00940446
- Testing
- Insorb staples, metal staples (Ethicon metal stapler)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Research Foundation
Pain, Postoperative
Erector Spinae vs Fascia Iliaca Block in Hip Arthroplasty
The thoracic erector spinae plane (ESP) block was first described by Forero et al in September 2016. In their article, the authors presented the possibility of using this block as an option for the control of thoracic neuropathic…
- Trial name
- ESFIBHA (NCT03860324)
- Testing
- Single-shot erector spinae plane block, Single-shot fascia iliaca block
- Where
- Portugal
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hospital Beatriz Ângelo