Clinical trials: Total Hip Replacement Surgery
Osteoarthritis, Pain
Safety of Non-delayed Weight Bearing After Total Hip Replacement With Non-Cemented Fiber Metal Taper Stem
The purpose of this study is to determine if full weight bearing following total hip replacement can speed recovery when the hip replacement in the long bone of the leg is not cemented into the bone.
- Trial name
- NCT00179088
- Testing
- Patient may be able to put weight on the operated leg
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Postoperative Cognitive Dysfunction
Postoperative Cognitive Dysfunction After Total Knee or Hip Replacement Surgery in Fast-track Set-up
The aim of this study is to quantify the incidence of postoperative cognitive dysfunction in the elderly patient (>60y) after total hip or knee replacement surgery.
- Trial name
- NCT01103752
- Testing
- no intervention, descriptive study
- Where
- Denmark
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Lene Krenk
Arthritis
Sexual Function Questionnaire Total Hip Replacement
Non-commercial trial 2 Centres involved: University Hospital Southampton and Spire Southampton Expected number of eligible participants available per year: 100, (95% expected to agree to participation) The study will recruit…
- Trial name
- NCT02290652
- Testing
- Prospective - Factors affecting sexual function pre-THR, Retrospective- Factors affecting sexual function post-THR
- Where
- 2 sites in United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Arthroplasty, Replacement, Hip
The Effect of Spouses' Involvement Through Case Management in Older Patients' Fast-track Program
Patients in fast-track programmes are required to take an active part in their treatment and rehabilitation. Spouses of older patients can often provide valued practical and emotional support, reducing stress, pain and length of…
- Trial name
- SICAM (NCT02561637)
- Testing
- Case management, Control group
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Hip Surgery Corrective
Functional Exercise After Total Hip Replacement
The aim of this research project is to evaluate the efficacy of a specific functional exercise programme to improve pain, stiffness and physical function in patients post total hip replacement from week 12 to week 18 post surgery.
- Trial name
- FEATHER (NCT01683201)
- Testing
- Functional exercise class, usual care group
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Health Service Executive, Ireland
Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip
Sleep Patterns After Total Joint Replacement Surgery
The purpose of this study is to determine sleep patterns and sleep quality following total joint arthroplasty, in order to understand when patients should expect to return to baseline or improved sleep following total joint…
- Trial name
- NCT04896892
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Chronic Hip Pain
Maveric Magnetic Resonance Imaging Used to Study Detailed Bone Apposition and Fixation of the Stryker Trident II Tritanium System
The study aims to describe bone apposition and fixation of the Trident and Trident II Tritatnium acetabular system in patients 1 year status post total hip replacement.
- Trial name
- NCT03469817
- Testing
- MRI
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Total Knee Replacement
Continuous Postoperative Pulse Oximetry in Patients Presenting for Total Hip and Total Knee Replacement
The purpose of this study is to evaluate the incidence of low levels of oxygen as determined by standard pulse oximetry monitor in patients who have had total hip or knee replacement/revision.
- Trial name
- NCT01189565
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Anesthesia, Orthopedic Surgery
Does Midazolam Cause Effective Anterograde Amnesia in Orthopedic Surgeries?
Spinal anesthesia is one of the commonest choices of anesthesia for infraumbilical surgeries.The use of sedation has markedly increased patients' comfort and acceptance towards spinal anesthesia.
- Trial name
- NCT04232150
- Testing
- single-dose midazolam for sedation under spinal anesthesia., Double-dose midazolam for sedation under spinal anesthesia., spinal anesthesia with no sedation.
- Where
- Jordan
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Degenerative Joint Disease
Study Comparing Regional Anesthetic Blocks and Periarticular Infiltration for the Management of Post-operative Pain After Direct Anterior Total Hip Arthroplasty
To compare two methods of post-operative pain management in patients undergoing total hip arthroplasty. There is a perception that the periarticular injections may not be as effective in controlling post-operative pain.
- Trial name
- DA THA pain (NCT02904993)
- Testing
- L2 paravertebral block, periarticular injection group
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Tranexamic Acid, Blood Loss, Surgical
Intravenous vs. Topical Tranexamic Acid in Revision THA (VITALITY-X)
The objective of this study is to evaluate and compare the effects of intravenous and topical administration of tranexamic acid during revision hip arthroplasty on blood loss, allogenic blood transfusion rates, length of hospital…
- Conditions
- Tranexamic Acid, Blood Loss, Surgical, Arthroplasty, Replacement, Hip
- Trial name
- VITALITY-X (NCT02938962)
- Testing
- Tranexamic Acid
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Hip Osteoarthritis, Indication for Total Hip Replacement
Evaluation of Locomotor Activity Before and After Total Hip Replacement in Patients With Hip Osteoarthritis.
The investigators believe that the application of non-linear methods of analysis using the ganglion and neural network technique will make it possible to analyse all of the complex data obtained in patients with hip…
- Trial name
- NCT02042586
- Testing
- Analysis of movement before total hip replacement, Analysis of movement after total hip replacement
- Where
- France
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Arthritis
Fascial Manipulation® Associated With Standard Care Versus Standard Post-surgical Care for Total Hip Arthroplasty
Post-surgical physiotherapy programs following to total hip arthroplasty (THA) show important differences between types and numbers of treatment sessions.
- Trial name
- NCT02576028
- Testing
- Fascial Manipulation® (FM), standard active exercises
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Bolognini di Seriate Bergamo
Osteoarthritis, Hip
Peri-Operative Testosterone Administration in Primary Total Hip Arthroplasty
It is often observed that patients following total hip replacement have a hard time with rehabilitation, as patients commonly lose muscle mass and strength around the surgical site.
- Trial name
- NCT06608914
- Testing
- Nandrolone decanoate, Saline
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- American Hip Institute
Metallosis, Pain
Neurotoxicity and Cardiotoxicity in Total Joint Arthroplasty
The purpose of this research is to understand whether patients who previously had total hip or total knee replacement experience memory, thinking or heart problems.
- Conditions
- Metallosis, Pain, Total Hip Replacement, Total Knee Replacement
- Trial name
- NCT04166539
- Testing
- Questionnaires, Interviews, Blood draw
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Total Hip Replacement, Wound Complication
Hip DAA Closure Techniques
This study aims to analyze the difference in rates of wound complications using two different closure techniques in Direct anterior approach for primary total hip replacement.
- Trial name
- NCT06006572
- Testing
- wound closure subcuticular running stitch using 3-0 monocryl suture without skin adhesive, wound closure subcuticular running stitch using 3-0 monocryl suture with two layers of skin adhesive
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Total Hip Replacement
The Postural Control in Patients After Total Hip Replacement
Total hip replacement (THR) is the procedure which can improve the quality of life in patients with osteoarthritis. However, deficits in static stability and impairment of the lower limb efficiency can be observed even several…
- Trial name
- NCT03218267
- Testing
- Static Posturography, One-leg standing test (OLS)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Total Hip Replacement
Action Observation in Hip Replacement
Postoperative rehabilitation is required for a successful outcome following total hip arthroplasty. Traditionally rehabilitative programs aim to increase range of motion, to strengthen quadriceps, to restore normal gait, and to…
- Trial name
- NCT02861638
- Testing
- Experimental group, Control group, Conventional physiotherapy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Osteoarthritis
RSA Study of Sirius Stem and Exceed Cup
The purpose of this study is to evaluate the efficacy and safety of the Sirius Cemented Stem used in conjunction with the Exceed ABT Cemented Acetabular Cup, either with E1 or Arcom polyethylene, and OptiPac/OptiVac bone cement…
- Trial name
- NCT02307331
- Testing
- Optivac, Optipac, Arcom (Exceed cup)
- Where
- Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Region Skane
Blood Loss After a Total Hip Replacement
Evaluating the Effectiveness of Intramuscular Versus Intravenous Tranexamic Acid for Minimizing Blood Loss After Total Hip Arthroplasty: A Randomized Controlled Trial
Intramuscular vs. Intravenous Tranexamic Acid for Total Hip Arthroplasty
- Trial name
- NCT07817537
- Testing
- Tranexamic Acid (TXA) intarmuscular, Tranexamic Acid (TXA) intravenous
- Where
- Egypt
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Alexandria University