Clinical trials: Total Hip Replacements
Rheumatoid Arthritis With Adequate Bone Quality, Inflammatory Arthritis
PMCF Study on the Safety and Performance of the Zimmer® Maxera™ Acetabular System in Total Hip Arthroplasty
This study is a multicenter, prospective, non-controlled post market clinical follow-up study. The objectives of this study are to confirm the safety and performance of the commercially available Zimmer® Maxera™ Acetabular System…
- Conditions
- Rheumatoid Arthritis With Adequate Bone Quality, Inflammatory Arthritis, Osteoarthritis, Hip, Avascular Necrosis
- Trial name
- NCT03372278
- Where
- 8 sites in Australia, Belgium and 6 more
- Volunteers
- 250 people
- Sponsor
- Zimmer Biomet
Degenerative Joint Disease
Study Comparing Regional Anesthetic Blocks and Periarticular Infiltration for the Management of Post-operative Pain After Direct Anterior Total Hip Arthroplasty
To compare two methods of post-operative pain management in patients undergoing total hip arthroplasty. There is a perception that the periarticular injections may not be as effective in controlling post-operative pain.
- Trial name
- DA THA pain (NCT02904993)
- Testing
- L2 paravertebral block, periarticular injection group
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Drainage
Evaluating the Effectiveness of 2 Surgical Skin Preparation Methods in Reducing Surgical Wound Drainage After Total Hip or Knee Replacement
Surgical skin complications can be costly and could contribute to extended in-patient stay following total joint replacement or even the need for re-admission.
- Trial name
- NCT01097135
- Testing
- Duraprep Surgical Solution
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Rothman Institute Orthopaedics
Total Hip Replacement, Reproducibility of Results
Reliability and Validity of the Six-Spot Step Test After Total Hip Arthroplasty
This study aims to assess the SSST's validity, reliability, and ability to differentiate between high and low fall risk individuals in THA patients.
- Conditions
- Total Hip Replacement, Reproducibility of Results, Rehabilitation
- Trial name
- SSST (NCT06704217)
- Testing
- Six Spot Step Test, Oxford Hip Score, Berg Balance Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Ordu University
Infection, Drainage
Comparison of Negative Pressure Wound Therapy vs. Conventional Dressings for Prevention of Wound Complications After Revision THA
Wound complications and surgical site infections following revision total joint arthroplasty result in significant morbidity and cost.
- Trial name
- NCT03321799
- Testing
- Negative Pressure Wound Therapy (NPWT), Sterile Antimicrobial Dressings
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Arthritis, Degenerative
Pilot Study Evaluating the Safety and Efficacy of a New Hard-on-Hard Total Hip Replacement System
The purpose of this study is to assess the early and long term safety and efficacy of the hard-on-hard total hip replacement system (R3 ODH-ODH utilization) in patients with non-inflammatory arthritis.
- Trial name
- NCT02154516
- Testing
- ODH Hip System
- Where
- 2 sites in South Africa
- Volunteers
- 26 people
- Sponsor
- Smith & Nephew, Inc.
Hip Replacement, Total
Balance Rehabilitation Based on Serious Games
The effects of new technologies, particularly exergames, on the rehabilitation process of patients with hip arthroplasty have not yet been verified.
- Trial name
- BERTHA (NCT06908564)
- Testing
- Experimental: Interactive balance rehabilitation based on serious games., Active Comparator: conventional balance rehabilitation without the use of technological devices.
- Where
- 2 sites in Italy
- Volunteers
- 53 people
- Sponsor
- IRCCS San Raffaele Roma
Osteoarthritis
Efficacy of Intravenous Versus Topical Tranexamic Acid in Primary Total Hip Arthroplasty
Bleeding during and after total hip replacement surgery is a primary concern to the surgical and anaesthetic team. Tranexamic acid is a commonly-used drug that helps blood clotting and decreases surgical bleeding.
- Trial name
- TeACH-R (NCT02056444)
- Testing
- Tranexamic Acid
- Where
- Canada
- Volunteers
- 149 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Total Hip Arthroplasty
Clinical Study and Economic Analysis of an Intraoperative Navigation System for Total Hip Arthroplasty
This study will assess the clinical and health economic value of an intraoperative navigation system for total hip arthroplasty in one Ontario hospital.
- Trial name
- INSTHA (NCT05416463)
- Testing
- Intra-Operative Device for THA
- Volunteers
- 190 people
- Sponsor
- Grand River Hospital
Analgesics, Opioid, Anesthesia, Spinal
Comparing the Safety and Effectiveness of Different Doses of Morphine Administered in Spinal Anethesia for Pain Relief After Hip Replacement Surgery
Pain management after total hip replacement is one of the most important aspects of postoperative care for patients and clinicians alike.
- Conditions
- Analgesics, Opioid, Anesthesia, Spinal, Total Hip Replacement, Adverse Anesthesia Outcome
- Trial name
- NCT06878014
- Testing
- Spinal Anesthesia (bupivacaine), Postoperative pain management with acetaminophen, PCA IV Oxycodone
- Where
- 3 sites in Poland
- Volunteers
- 120 people
- Sponsor
- Medical University of Silesia
Anesthesia, Local, Analgesia
The Efficacy of Suprainguinal Fascia Iliaca Compartment Block for Analgesia After Elective Total Hip Replacement.
Total hip replacement surgery is one of the most common orthopedic interventions. Proper anaesthesia and adequate analgesia is one of the key interests of attending anaesthetist.
- Conditions
- Anesthesia, Local, Analgesia, Arthropathy of Hip
- Trial name
- NCT04690647
- Testing
- Opioid and non opioid postoperative analgesia., Fascia iliaca compartment block, Dexamethasone
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Saint Lucas Hospital, Poland
Total Hip Arthroplasty (THA)
Mpact 3D Metal Monolit Study
Total hip arthroplasty (THA) is one of the most common operations performed in orthopaedics to improve a patient's quality of life.
- Trial name
- NCT06748885
- Testing
- Mpact 3D Metal Monolith
- Where
- 3 sites in France
- Volunteers
- 88 people
- Sponsor
- Medacta International SA
Venous Thromboembolism, Bleeding
Prospective Genotyping For Total Hip or Knee Replacement Patients Receiving Warfarin (Coumadin)
Several human genes affect how medications are metabolized by the body. It is believed that knowledge of variations of these genes can help health care providers better manage an anticoagulation medicine called warfarin…
- Trial name
- NCT00634907
- Testing
- Pharmacogenetic-based warfarin dosing, Usual care warfarin dosing
- Where
- United States
- Volunteers
- 263 people
- Sponsor
- Gwen McMillin
Hip Replacement Arthroplasty
Determination of Metal Ion Serum Levels and Cytokines in Total Hip Replacement
The goal of the study is the analysis of metal ion serum concentrations and of the cytokine production in the blood of patients with a conventional cementless total hip replacement.
- Trial name
- NCT01394744
- Where
- 2 sites in Germany
- Volunteers
- 30 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Testing Implementation of Total Joint Replacement Rehabilitation Quality Indicator Toolkits
The goal of this feasibility study is to test the procedures for implementing quality indicator toolkits for hip and knee replacement rehabilitation in clinical settings.
- Trial name
- NCT06208553
- Testing
- QI toolkit implementation
- Where
- Canada
- Volunteers
- 135 people
- Sponsor
- University of British Columbia
Hypothermia Following Anesthesia, Hypothermia; Anesthesia
Preoperative Warming, Hypothermia and Functional Recovery in Total Hip Arthroplasty
This prospective, randomized, single-center study compares intraoperative heat loss at the core temperature level in patients scheduled for direct anterior total hip arthroplasty under general anesthesia and who will or will not…
- Trial name
- NCT05213377
- Testing
- Preoperative warming
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University of Liege
Osteoarthritis, Total Hip Arthroplasty
Lumbar Plexus Block Versus Quadratus Lumborum Block for Primary Anterior Total Hip Arthroplasty
Total hip arthroplasty (THA) is one of the most successful orthopedic procedures to effectively relieve pain and restore function in patients with end stage osteoarthritis.
- Trial name
- NCT03409900
- Testing
- LPB, QLB
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Wake Forest University Health Sciences
Osteoarthritis
Comparison of Two Minimally Invasive Surgical Techniques for Hip Replacement
Comparison of the clinical effectiveness and cost-effectiveness of the MIS anterolateral approach (MIS Watson Jones, G3) versus anterolateral mini or posterolateral mini approaches in primary total hip arthroplasty
- Trial name
- NCT00175461
- Testing
- hip surgery
- Where
- Canada
- Volunteers
- 156 people
- Sponsor
- University of British Columbia
Total Hip Arthroplasty, Total Hip Replacement
Total Hip Replacement With Ceramic on Ceramic Bearing- Clinical Follow-up Study
The pain and severe wear of hip joints caused by osteoarthritis, rheumatoid arthritis, avascular necrosis and trauma can be subjected to total hip replacement (THR).
- Trial name
- NCT04256291
- Where
- Taiwan
- Volunteers
- 160 people
- Sponsor
- National Taiwan University Hospital
Hip Replacement, Total
Tranexamic Acid Versus Placebo for the Reduction of Blood Loss in Total Hip Replacement Surgery
The bleeding caused by hip replacement surgery (CRT) is an important source of demand for blood in the hospital. Tranexamic acid (TXA) is a drug that has proved useful in reducing bleeding associated with other surgeries and CRT…
- Trial name
- TXA-CRT (NCT01199627)
- Testing
- A, B, C
- Where
- Spain
- Volunteers
- 114 people
- Sponsor
- Basque Health Service