Clinical trials: Total Hip Surgery
Venous Thromboembolism
Dose-confirmatory Bridging Study in Total Hip Replacement
The objective of this dose-confirmatory bridging study is to investigate the safety and efficacy of rivaroxaban 5 to 10 mg once-daily (od) dosing in the prevention of venous thromboembolism (VTE) in Japanese patients undergoing…
- Trial name
- NCT01205932
- Testing
- Rivaroxaban (BAY59-7939), Enoxaparin
- Where
- 41 sites in Japan
- Volunteers
- 402 people
- Sponsor
- Bayer
Postoperative Cognitive Dysfunction (POCD), Cognitive Change
Early Cognitive Changes After Same-day Discharge Hip and Knee Arthroplasty
The goal of this observational study is to explore early cognitive changes in patients aged 70 years or older undergoing same-day discharge after hip or knee replacement surgery.
- Conditions
- Postoperative Cognitive Dysfunction (POCD), Cognitive Change, Total Knee Arthroplasty, Unicompartmental Knee Arthroplasty
- Trial name
- NCT07598552
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Odense University Hospital
Arthropathy of Hip, Surgery
Consequence of the Learning Curve in Direct Anterior Approach for Total Hip Replacement
Background: Direct anterior approach to the hip (DAA) is being considered as one of the most promising minimally-invasive approaches in total hip arthroplasty (THA).
- Trial name
- NCT02645435
- Testing
- hip replacement
- Volunteers
- 69 people
- Sponsor
- Azienda Ospedaliera Bolognini di Seriate Bergamo
Primary Arthritis, Secondary Arthritis
A Multi-centre Study to Assess the Long-term Performance of the Silent Hip™ in Primary Total Hip Replacement Surgery
The purpose of this study is to monitor the performance and of the Silent Hip™ in the treatment of patients with hip joint disease requiring a total hip replacement.
- Trial name
- NCT01383824
- Testing
- Silent™ Hip
- Where
- 9 sites in Denmark, Germany and 3 more
- Volunteers
- 89 people
- Sponsor
- DePuy International
Venous Thromboembolism, Total Hip Arthroplasty (THA)
The Effect of a VTE Prevention Care Bundle in Total Hip Arthroplasty Patients
Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), remains a critical and potentially life-threatening complication following total hip arthroplasty (THA).
- Conditions
- Venous Thromboembolism, Total Hip Arthroplasty (THA), Deep Vein Thrombosis
- Trial name
- VTE-CARE-THA (NCT07702903)
- Testing
- VTE Prevention Care Bundle, Standard Routine Care
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Murat Erten
Intraoperative Blood Loss
The Effect of Administration of Low Dose Adrenaline During Surgery on Bleeding During Hip Surgery
The purpose of this study is to evaluate the effect of intraoperative administration of low-dose adrenaline on intraoperative blood loss in patients undergoing hip surgery.
- Trial name
- NCT01708642
- Testing
- Adrenaline
- Where
- 3 sites in Denmark
- Volunteers
- 106 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Osteoarthritis
Comparison of Two Minimally Invasive Surgical Techniques for Hip Replacement
Comparison of the clinical effectiveness and cost-effectiveness of the MIS anterolateral approach (MIS Watson Jones, G3) versus anterolateral mini or posterolateral mini approaches in primary total hip arthroplasty
- Trial name
- NCT00175461
- Testing
- hip surgery
- Where
- Canada
- Volunteers
- 156 people
- Sponsor
- University of British Columbia
Osteoarthritis, Blood Loss, Surgical
Non-inferiority Trial of Oral Tranexamic Acid vs. Intravenous Tranexamic Acid in Joint Replacement Surgery
The purpose of this research is to determine if the oral form of a medication (tranexamic acid) to reduce bleeding can be used in place of an intravenous (IV) form, to learn the best way to give tranexamic acid: either a pill by…
- Conditions
- Osteoarthritis, Blood Loss, Surgical, Blood Loss, Postoperative
- Trial name
- NCT02438566
- Testing
- Tranexamic Acid (Oral), Tranexamic Acid (Intravenous)
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- The New England Baptist Hospital
Anesthesia, Orthopedic Surgery
Does Midazolam Cause Effective Anterograde Amnesia in Orthopedic Surgeries?
Spinal anesthesia is one of the commonest choices of anesthesia for infraumbilical surgeries.The use of sedation has markedly increased patients' comfort and acceptance towards spinal anesthesia.
- Trial name
- NCT04232150
- Testing
- single-dose midazolam for sedation under spinal anesthesia., Double-dose midazolam for sedation under spinal anesthesia., spinal anesthesia with no sedation.
- Where
- Jordan
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Arthroplasty, Recovery of Function
The Influence of Rapid Recovery on Sleep Quality Following Total Hip Replacement Surgery
To evaluate the influence of rapid recovery on sleep quality following total hip replacement surgery
- Conditions
- Arthroplasty, Recovery of Function, Sleep Quality
- Trial name
- NCT02852460
- Testing
- rapid recovery
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Southwest Hospital, China
Hip Osteoarthritis
Minimal Invasive Surgery in Total Hip Arthroplasty Patients; Short- and Long Term Results
The aim of the present study is to explore the most efficient surgical approach in total hip replacement in short and long term when concerning strength, functionality and postoperative complications.
- Trial name
- NCT01506024
- Testing
- Total hip arthroplasty direct lateral approach, Total hip arthroplasty posterior approach, Total hip arthroplasty, anterior approach
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Norwegian University of Science and Technology
Hip Osteoarthritis
A Prospective Multi-center Study on Total Hip Arthroplasty With E1
The primary objectives of this clinical study include: Evaluate E1 Wear including early bedding-in process, clinical outcomes on patients who received Total Hip Arthroplasty with E1 Compare E1 wear used with CoCr and Biolox Delta…
- Trial name
- NCT01883492
- Testing
- Femoral Stem, Acetabular Cup, Acetabular Liner
- Where
- 5 sites in Japan
- Volunteers
- 153 people
- Sponsor
- Zimmer Biomet
Total Hip Arthroplasty
Effectiveness of Fast-track Clinical Pathway on Minimally-invasive Total Hip Arthroplasty Surgery in NTUH
The objective of this study was to evaluate the effects of an enhanced recovery after surgery (ERAS) pathway incorporated with pre-operative physical therapy and education on immediate and short-term outcomes of…
- Trial name
- NCT04145921
- Testing
- ERAS for MIS-THA, conventional MIS-THA
- Volunteers
- 75 people
- Sponsor
- National Taiwan University Hospital
Total Hip Arthroplasty
Study of Two Surgical Approaches for Total Hip Arthroplasty
A prospective, comparative, randomized single surgeon study comparing minimally invasive total hip arthroplasty (MIS) via anterior approach to conventional total hip arthroplasty via anterolateral transgluteal approach.
- Trial name
- NCT00881998
- Testing
- Minimally Invasive Total Hip Arthroplasty, Conventional Total Hip Arthroplasty
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rothman Institute Orthopaedics
Total Knee Arthroplasty (Postoperative Pain), Total Hip Arthroplasty(Postoperative Pain)
Dose Dependent Effects of tDCS on Post-Operative Pain
The proper control of acute and chronic pain is one of the most important areas in health care. Despite the profound advances in neuroscience over the past 20 years, the investigators still largely use opiate narcotics, much as…
- Trial name
- tDCS-TKA (NCT02241967)
- Testing
- 4 Real sessions of Transcranial Direct Current Stimulation, 2 Real Sessions of Transcranial Direct Current Stimulation, 1 Real Session of Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- VA Office of Research and Development
Hip Osteoarthritis, Complications; Arthroplasty
Correlation of Spinopelvic Parameters and Acetabular Cup Orientation
In total hip arthroplasty, cup anteversion is an important factor in stability. Lewinnek's safe zone and functional anteversion are often used to assess appropriate orientation.
- Trial name
- NCT02598700
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Duke University
Postoperative Pain, Postoperative Nausea and Vomiting
High-Dose Steroid for Hip Arthroplasty Patients Expected to Have Postoperative Pain
The purpose of the Study is to test a higher dose of steroids(Dexamethasone) given just prior to surgery in the setting of Fast-Track Hip-surgery with Arthroplasty in a group of expected High Pain Responders and the effect on…
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Hip Osteoarthritis, Perioperative/Postoperative Complications
- Trial name
- NCT03763760
- Testing
- Dexamethasone
- Where
- 2 sites in Denmark
- Volunteers
- 160 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Hip Replacement Surgery, Hip Replacement, Total
OPPOSED (anteriOr hiP arthroPlasty regiOnal aneSthEsia stuDy) Study
Main indications for total hip arthroplasty (THA) are degenerative osteoarthritis of the coxofemoral joint, osteonecrosis of the hip, congenital disorders such as dysplasia and inflammatory arthritis.
- Conditions
- Hip Replacement Surgery, Hip Replacement, Total, Hip Pain, Hip Arthroplasty
- Trial name
- NCT07017192
- Testing
- SIFI Block, ESP block
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Anterior Cruciate Ligament Reconstruction, Total Hip Arthroplasty (THA)
Brain-Computer Interface Visualization Training to Optimize Muscle Activation Following Orthopaedic Surgery
After orthopedic surgeries like knee or hip replacement, some patients struggle to fully activate their muscles due to a condition called Arthrogenic Muscle Inhibition (AMI).
- Conditions
- Anterior Cruciate Ligament Reconstruction, Total Hip Arthroplasty (THA), Total Knee Arthroplasty, Hip Arthroscopy
- Trial name
- iBrainTechRCT (NCT07020312)
- Testing
- Visualization training with neurofeedback, Standard post-surgical rehabilitation therapy
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Rush University Medical Center
Hip Replacement
A Novel Study Evaluating Patients Awaiting Total Hip Arthroplasty (PRIORITEES)
Hip replacements are one of the NHS's highest volume procedures, with ~14,000 operations per month before the onset of the COVID-19 pandemic.
- Trial name
- PRIORITEES (NCT06178185)
- Where
- United Kingdom
- Volunteers
- 240 people
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust