Clinical trials: Total Joint Arthroplasty
Hip Osteoarthritis, Arthroplasty, Replacement, Hip
Addressing Patients' Expectations of Total Hip Arthroplasty in a Randomized Trial
The goals of this study are to develop and test an educational intervention to address patients' expectations of long-term outcomes of total hip arthroplasty.
- Trial name
- NCT00198003
- Testing
- Educational program to address patients' expectations
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Hospital for Special Surgery, New York
Knee Arthroplasty, Total, Robotic Assisted Arthroplasty
Randomized Controlled Trial Comparing Robotic-Assisted Versus Conventional Total Knee Arthroplasty
To evaluate whether patients undergoing robotic-assisted TKA achieve better clinical-functional, radiological, and satisfaction outcomes compared with those undergoing the conventional technique, and whether operative time and…
- Conditions
- Knee Arthroplasty, Total, Robotic Assisted Arthroplasty, Arthropathy of Knee
- Trial name
- NCT07212296
- Testing
- Conventional total knee replacement, Robotic TKR
- Where
- Spain
- Volunteers
- 95 people
- Sponsor
- Hospital de Terrassa
Musculoskeletal Diseases
Medacta NextAR TKA Pivotal Trial
The goal of this study is to assess the efficacy and safety of a navigation system providing personalized soft tissue balance data in medially-stabilized total knee arthroplasty (TKA).
- Trial name
- NCT04844879
- Testing
- NextAR TKA system
- Where
- 4 sites in Switzerland
- Volunteers
- 40 people
- Sponsor
- Medacta International SA
Pain, Osteoarthritis
Adductor Canal Block With Posterior Capsular Injection for Total Knee Replacement
To compare early ambulation and ability to participate in rehabilitation in patients undergoing total knee replacement using two different nerve block techniques for pain control.
- Trial name
- NCT01805661
- Testing
- Canal Block and Capsular Injection, Femoral with Tibial Nerve Block
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Trinity Health Of New England
Total Knee Anthroplasty, Venous Insufficiency (Chronic)(Peripheral)
Impact of Chronic Venous Insufficiency on Outcomes After Total Knee Arthroplasty
Total knee arthroplasty (TKA) is an effective treatment for end-stage knee osteoarthritis; however, postoperative complications-particularly wound healing problems-remain a significant concern.
- Conditions
- Total Knee Anthroplasty, Venous Insufficiency (Chronic)(Peripheral), Doppler Ultrasound Diagnosis
- Trial name
- VENOUS-TKA (NCT07577141)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- SB Istanbul Education and Research Hospital
Osteoarthritis
A Study on Rosa Roxburghii for Knee Replacement Recovery
This clinical trail is to investigates the effect of Rosa roxburghii juice freeze-dried powder on the recovery of patients undergoing total knee arthroplasty due to knee osteoarthritis.
- Trial name
- NCT07395856
- Testing
- Rosa roxburghii
- Volunteers
- 184 people
- Sponsor
- Shuguang Gao
Hip Arthropathy
Anterior Iliopsoas Muscle Space Block Versus Supra-iliac Anterior Quadratus Lumborum Block in Total Hip Arthroplasty
Approximately 1.66 million hip fractures happen in a year worldwide. About 95% of these fractures happen in individuals older than 60 years.
- Trial name
- NCT05556759
- Testing
- control, IPS, Supra-iliac QL
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Zagazig University
Total Knee Anthroplasty, Patient Reported Outcome Measurements
Recovery Trajectories After Total Knee Arthroplasty
This prospective cohort study aimed to compare recovery trajectories following cruciate-retaining (CR) and posterior-stabilized (PS) total knee arthroplasty (TKA) using rehabilitation-centered patient-reported outcome measures…
- Conditions
- Total Knee Anthroplasty, Patient Reported Outcome Measurements, Cruciate Ligament Reconstruction
- Trial name
- NCT07595861
- Testing
- Cruciate-Retaining Total Knee Arthroplasty, Posterior-Stabilized Total Knee Arthroplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Femur Fracture
Anterolateral Versus Posterior Approach for Total Hip Arthroplasty After Displaced Femoral Neck Fracture
There are two surgical approaches (incision types) used by surgeons who do total hip replacements. The purpose of this study is to determine which type of surgical approach (incision type) produces the best results for patients…
- Trial name
- THA (NCT01484405)
- Testing
- posterior approach, anterolateral approach
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Florida Orthopaedic Institute
Knee Osteoarthritis
Effect of Noise Control During Total Knee Arthroplasty
Music has emerged as a well-received medical intervention. Patients may be uncomfortable during total joint replacement, which can result in high sedation requirements. These requirements put patients at risk of surgical stress.
- Trial name
- NCT05714267
- Testing
- Active noise cancelling, Passive noice cancelling, Active noise cancelling with music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bezmialem Vakif University
Total Hip Arthroplasty (THA), Impaction
Automated V Manual Impactor Study
This study investigates the use of an automated impactor device in total hip arthroplasty versus manual malleting method and the physiological strain on the surgeon.
- Conditions
- Total Hip Arthroplasty (THA), Impaction, Physiological Strain
- Trial name
- NCT06903767
- Testing
- Automated Impaction (HAMMR), Manual Malleting
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Hip Osteoarthritis
Comparison of Hip Resurfacing and Cementless Metal-on-metal Total Hip Arthroplasty
To compare clinical, functional and radiological outcome after hip resurfacing and cementless metal-on-metal total hip arthroplasty.
- Trial name
- NCT00570167
- Testing
- Hip resurfacacing, Cementless total hip arthroplasty with m-o-m bearings
- Where
- 3 sites in Finland
- Volunteers
- 71 people
- Sponsor
- University of Helsinki
Arthroplasty, Replacement, Knee, Pain, Postoperative
Central Sensitization and Alteration of Circulating Neurosteroid
For patients who underwent two-stage replacement of both knee joints (one knee surgery - one week term- the other knee surgery), postoperative pain and analgesic usage with patient-controlled analgesia (PCA) increased at the…
- Trial name
- NCT03298711
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Seoul National University Bundang Hospital
Osteoarthritis, Knee
Pre-operative Intravenous Steroid in Total Knee Replacement for Pain Relief and Recovery
Osteoarthritis of the knee is a common and important condition in our society. Despite various anesthetic methods and pain medications, pain after operation still remains as a challenge.
- Trial name
- NCT03082092
- Testing
- Methylprednisolone Sodium Succinate
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Queen Elizabeth Hospital, Hong Kong
Knee Osteoarthritis, Knee Arthropathy
Mechanical Alignment vs Kalipered Kinematic Alignment Total Knee Arthroplasty
Knee replacement surgery can be performed in one of two ways. Traditionally the goal was for the new joint to be in a neutral position with respect to the femur (thigh bone). This is called Mechanical Alignment (MA).
- Trial name
- NCT06617871
- Testing
- Mechanical Alignment (MA), Kinematic Alignment (KA) Interventions:
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Northwestern University
Osteo Arthritis
Bone Forming at Prosthetic Surfaces. Fingerprint2
What is the intensity of F-PET uptake in healthy and osteo arthritic femur and acetabulum, compared to the uptake adjacent to four analyzed endoprosthetic components 1½ and 6 months after surgery?
- Trial name
- NCT01623687
- Testing
- Component for acetabulum (Regenerex RingLoc cup), Components for the acetabulum (Lubinus cross linked cup), Arthroplasty components are for the femur (Cemented Lubinus SP II stem)
- Where
- Sweden
- Volunteers
- 26 people
- Sponsor
- Uppsala University
Total Knee Arthroplasty
Comparison Between Brainlab Knee 3 Computer-assisted Navigation Systems and Conventional Instruments in TKA: a Prospective Cohort Study.
This is a a prospective cohort study. According to the inclusion criteria, volunteers were recruited from patients undergoing total knee arthroplasty.
- Trial name
- NCT04960345
- Testing
- Brainlab Knee 3
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Osteoarthritis, Knee
Reinflation After Early Tourniquet Release in Total Knee Arthroplasty
This study is aimed to determine the efficacy and the safety of the tourniquet reinflation after early tourniquet release in total knee arthroplasty, compared to the method of early deflation without reinflation.
- Trial name
- NCT01832272
- Testing
- Reinflation after early tourniquet deflation
- Where
- South Korea
- Volunteers
- 174 people
- Sponsor
- Seoul National University Hospital
Pain and Mobility Levels of Patients Undergoing Total Knee Prosthesis During Continuous Passive Motion Exercise, Total Knee ArthroplastyKnee Pain, Functionality
Stress Ball and Hand Holding on Pain After Knee Arthroplasty
Pain after Total Knee Arthroplasty. (TKA) is an important problem When pain is not controlled, it can negatively affect the patients; mobility level.This research; A randomized controlled experimental design was planned to…
- Trial name
- NCT06608264
- Testing
- Stress Ball, Hand Holding
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Necmettin Erbakan University
Complications; Arthroplasty
A Comparison Between an Individual Low Tourniquet Pressure Versus a Standard Pressure During Total Knee Arthroplasty
The use of bloodless field is a helpful and important method in orthopedic surgery. The surgery can be done without interrupting bleedings, while keeping an exact overlook of the anatomy.
- Trial name
- NCT01442298
- Testing
- Limb occlusion pressure (LOP), conventional measurement method
- Where
- Sweden
- Volunteers
- 164 people
- Sponsor
- Charlotta Olivecrona
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