Clinical trials: Total Knee Arthroplasty Recovery
Total Knee Arthroplasty Recovery, Knee Osteoarthritis
Wearable Knee-Assisted Rehabilitation for Range of Motion and Muscle Strength After Total Knee Arthroplasty
This randomized controlled trial evaluates a wearable electrogoniometry-based telerehabilitation system designed to support recovery after total knee arthroplasty.
- Trial name
- NCT07875725
- Testing
- ReBK Wearable Telerehabilitation System, Standard Home-Based Rehabilitation
- Where
- 3 sites in Chile
- Volunteers
- 80 people
- Sponsor
- University of Chile
Arthroplasty, Replacement, Knee, Nerve Block
Does Continuous Adductor Canal Nerve Block Improve the Quality of Recovery for Outpatient Total Knee Arthroplasty Patients?
This is a randomized, double-blinded pilot study to determine whether patients undergoing ambulatory total knee arthroplasty (TKA) using a subvastus approach benefit from the addition of a continuous adductor canal nerve block…
- Conditions
- Arthroplasty, Replacement, Knee, Nerve Block, Anesthesia, Regional, Ambulatory Surgical Procedures
- Trial name
- NCT03038425
- Testing
- Normal Saline, Ropivacaine
- Where
- Canada
- Volunteers
- 81 people
- Sponsor
- Ottawa Hospital Research Institute
Knee Osteoarthritis (OA), Postoperative Pain
Effect of Adding a Biceps Femoris Short Head Block to Adductor Canal Block for Analgesia After Total Knee Arthroplasty
Total knee arthroplasty (TKA) is frequently associated with moderate to severe postoperative pain, which may delay mobilization, increase opioid consumption, and impair functional recovery.
- Trial name
- BiFeS-TKA (NCT07803887)
- Testing
- Ultrasound-Guided Adductor Canal Block, Ultrasound-Guided Biceps Femoris Short Head Block
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Antalya Training and Research Hospital
Total Knee Arthroplasty, Postoperative Oral Carbohydrates
Effect of Postoperative Oral Carbohydrate Administration in Total Knee Arthroplasty Elderly Patients
To evaluate the effects of early oral carbohydrates after TKA on nutritional status, comfort and safety in elderly patients.
- Conditions
- Total Knee Arthroplasty, Postoperative Oral Carbohydrates, Postoperative Recovery, Elderly Patients
- Trial name
- NCT05603364
- Testing
- 100ml carbohydrate containing 12.5g maltodextrin, fructose and glucose, Routine feeding
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Osteoarthritis, Hip, Osteoarthritis, Knee
Spinal Anaesthesia vs. General Anaesthesia for THA, TKA and UKA
The goal of this randomized clinical trial is to investigate the postoperative recovery following hip and knee arthroplasty procedures depending on the use of either spinal anaesthesia (SA) or general anaesthesia (GA).
- Trial name
- RCT SAGA (NCT05706844)
- Testing
- Spinal anesthesia, General anaesthesia
- Where
- 2 sites in Denmark
- Volunteers
- 222 people
- Sponsor
- Anders Troelsen
Osteoarthritis, Knee
Pre-operative Intravenous Steroid in Total Knee Replacement for Pain Relief and Recovery
Osteoarthritis of the knee is a common and important condition in our society. Despite various anesthetic methods and pain medications, pain after operation still remains as a challenge.
- Trial name
- NCT03082092
- Testing
- Methylprednisolone Sodium Succinate
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Queen Elizabeth Hospital, Hong Kong
Osteoarthritis, Knee, Postoperative Pain
A Randomized Comparison of the Efficacy of the IPACK Block Versus the Popliteal Plexus Block for Posterior Knee Analgesia, in Patients Undergoing a Total Knee Arthroplasty and Receiving a Continuous Distal Femoral Triangle Block
Total knee arthroplasty (TKA) is commonly associated with significant postoperative pain, including pain arising from the posterior aspect of the knee.
- Trial name
- NCT07876310
- Testing
- Ultrasound-Guided iPACK Block, Ultrasound-Guided Popliteal Plexus Block, Ultrasound-Guided Continuous Femoral Triangle Block
- Volunteers
- 136 people
- Sponsor
- Clinica Santa Maria
Knee Arthropathy
Persistent Post Surgical Pain After Total Knee Arthroplasty
Patients undergone total knee replacement are randomized to receive a "fast track" regional anesthesia protocol or a "traditional" regional anesthesia continuous infusion by both a femoral and sciatic catheter to assess if this…
- Trial name
- NCT06182059
- Testing
- continuous peripheral nerve block
- Where
- Italy
- Volunteers
- 436 people
- Sponsor
- Policlinico di Monza SpA
Swelling
Fast Track Recovery Knee Arthroplasty Project
Fast Track Recovery Arthroplasty Project is supposed to analyse a new medical method to accelerate patient's remobilisation process after total knee endoprostheses.
- Trial name
- FARP (NCT01551017)
- Where
- Austria
- Volunteers
- 80 people
- Sponsor
- Medical University of Graz
Arthroplasty, Replacement, Knee, Recovery of Function
The Influence of Rapid Recovery on Sleep Quality Following Total Knee Replacement Surgery
The purpose of this study is to evaluate the influence of rapid recovery on sleep quality following total knee replacement surgery.
- Conditions
- Arthroplasty, Replacement, Knee, Recovery of Function, Arthritis, Rheumatoid
- Trial name
- NCT02845960
- Testing
- rapid recovery
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Southwest Hospital, China
Surgery
Peanut Protein Supplementation to Prevent Muscle Atrophy and Improve Recovery Following Total Knee Arthroplasty
This randomized controlled trial will study the effects of peanut protein supplementation on changes in muscle size and quality in patients undergoing total knee arthroplasty.
- Trial name
- NCT04294563
- Testing
- Peanut Protein Powder, Standard Care by Surgeon and Physical Therapist
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Auburn University
Anesthesia, Knee Osteoarthritis
The Assessment of Postoperative Recovery in Elder Diabetic Patients
Total Knee Replacement (TKR) performed under general anesthesia is a common successful orthopedic procedure. Nonetheless, in elder patients with diabetes mellitus (DM) this procedure can present unique challenges to orthopedic…
- Trial name
- TKRDM2013 (NCT01871012)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chinese PLA General Hospital
Hip Arthroplasty, Knee Arthroplasty
Anaesthesia for Hip and Knee Arthroplasty (SPIGA)
Beneficial and harmful effects of spinal versus general anaesthesia in patients undergoing hip and knee arthroplasty.
- Conditions
- Hip Arthroplasty, Knee Arthroplasty, Spinal Anesthesia, General Anesthesia
- Trial name
- SPIGA (NCT07834242)
- Testing
- Spinal anaesthesia, General anaesthesia
- Volunteers
- 3,000 people
- Sponsor
- Zealand University Hospital
Total Knee Replacement
Total Knee Replacement Under Spinal Anesthesia, Comparison of Postoperative Recovery Versus General Anesthesia
Intraoperative anesthetic management for total knee replacement (TKR) can be performed under general or spinal anesthesia. These two techniques have their own characteristics and may impact postoperative recovery differently.
- Trial name
- PTG-RachiVsAG (NCT07275983)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
Sarcopenia in Elderly, Frailty at Older Adults
Effect of Micronized Creatine Monohydrate on Muscle Mass, Strength and Performance in Older Adults Submitted to Total Knee Arthroplasty
Double-blind randomized placebo-controlled clinical trial with two parallel arms. The main objective is to evaluate the efficacy and safety of creatine supplementation in older adults who have been operated on for total knee…
- Conditions
- Sarcopenia in Elderly, Frailty at Older Adults, Functional Capacity, Creatine Supplementation
- Trial name
- CREAR (NCT06925880)
- Testing
- Creatine Monohydrate
- Where
- Spain
- Volunteers
- 262 people
- Sponsor
- Consorci Sanitari del Maresme
Total Knee Arthroplasty
A Prospective Clinical Study Evaluating the Newton™ TKA Protocol
Evaluation of clinical outcomes and patient recovery in patients receiving TKA with traditional instrumentation systems compared to full arc of motion gap balancing using the Newton TM Knee Protocol
- Trial name
- NCT06678750
- Testing
- TKA using computer navigation, TKA
- Where
- United States
- Sponsor
- Newton-Wellesley Hospital
Patient Reported Outcome Measure
Comparison of Functional Recovery Between Mobile Bearing Unicompartmental Knee Arthroplasty and Total Knee Arthroplasty
The total knee replacement (TKA) has shown excellent survival. However, some patients were up to 20%, they still had pain and make them dissatisfy after operation.
- Trial name
- NCT04419129
- Testing
- Oxford UKA, Vanguard TKA
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Thammasat University
Total Knee Replacement
Impact of Adductor Canal Block on Functional Recovery
TKA involves extensive bone resection as well as soft tissue excision and therefore is associated with profound postoperative pain.
- Trial name
- NCT04814303
- Testing
- Intrathecal morphine, Adductor Canal block, Peri-articular Infilteration
- Volunteers
- 200 people
- Sponsor
- Assiut University
Anxiety, Recovery Quality
Effect of Virtual Reality Application Applied to Patients With Total Knee Replacement at Different Times
The aim of this study was to examine the effect of virtual reality application on anxiety and quality of recovery at different times (preoperatively and intraoperatively) in patients undergoing total knee replacement.
- Trial name
- NCT06792123
- Testing
- pre-op VR application group, intra-op VR application group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Özge İşeri
Arthroplasty, Replacement, Knee, Osteoarthritis, Knee
Nurse-Led Telehealth vs In-Person Follow-Up After Total Knee Replacement
Brief Summary The goal of this clinical trial is to learn if nurse-led telehealth consultations can help detect complications and support recovery after total knee replacement surgery.
- Trial name
- NCT07058623
- Testing
- Nurse-Led Telehealth Consultation, Traditional In-Person Nursing Consultation
- Where
- Hong Kong
- Volunteers
- 98 people
- Sponsor
- Hospital Authority, Hong Kong