Clinical trials: Total Knee Arthroplasty Recovery
Arthroplasty, Replacement, Knee, Nerve Block
Does Continuous Adductor Canal Nerve Block Improve the Quality of Recovery for Outpatient Total Knee Arthroplasty Patients?
This is a randomized, double-blinded pilot study to determine whether patients undergoing ambulatory total knee arthroplasty (TKA) using a subvastus approach benefit from the addition of a continuous adductor canal nerve block…
- Conditions
- Arthroplasty, Replacement, Knee, Nerve Block, Anesthesia, Regional, Ambulatory Surgical Procedures
- Trial name
- NCT03038425
- Testing
- Normal Saline, Ropivacaine
- Where
- Canada
- Volunteers
- 81 people
- Sponsor
- Ottawa Hospital Research Institute
Total Knee Arthroplasty (Replacement)
A Study on the Physiological Outcomes of the Enhanced Recovery After Surgery Model in Older Adults Undergoing Total Knee Arthroplasty
With the advent of an aging society, the demand for total knee arthroplasty (TKA) continues to increase. Postoperative recovery is influenced not only by the surgical procedure itself but also by pain control, joint function, and…
- Trial name
- NCT07828418
- Testing
- Enhanced Recovery After Surgery (ERAS) Care Pathway, Usual Perioperative Care
- Volunteers
- 60 people
- Sponsor
- China Medical University Hospital
Arthroplasty, Replacement, Knee, Recovery of Function
The Influence of Rapid Recovery on Sleep Quality Following Total Knee Replacement Surgery
The purpose of this study is to evaluate the influence of rapid recovery on sleep quality following total knee replacement surgery.
- Conditions
- Arthroplasty, Replacement, Knee, Recovery of Function, Arthritis, Rheumatoid
- Trial name
- NCT02845960
- Testing
- rapid recovery
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Southwest Hospital, China
Knee Arthritis
The Efficacy of Collaborative Patient Education on Total Knee Arthroplasty
This project is about the integrated rehabilitation program for the patients receiving total knee arthroplasty. The investigators are monitoring the WOMAC(Western Ontario and Mcmaster University Arthritis Index)/ Pain…
- Trial name
- NCT05346822
- Testing
- integrated rehabilitation (the collaborative patient education)
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Total Knee Arthroplasty, Knee Osteoarthritis
Adductor Canal Block in an Enhanced Recovery Program After Total Knee Arthroplasty
The purpose of this study is to assess the effectivity of adductor canal block performed the day after total knee arthroplasty surgery in reducing pain and improving walking ambulation ability and muscle strength.
- Trial name
- NCT03915522
- Testing
- Single adductor canal block, Simulated adductor canal block
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Institut de Recerca Biomèdica de Lleida
Knee Osteoarthritis (OA), Artrosis of the Knee
PROPRIOCEPTION, KINESIOPHOBIA AND FUNCTIONAL RECOVERY AFTER GONARTHROSIS SURGERY
This observational study aims to investigate the relationships between proprioception, causes of kinesiophobia, sensory processing characteristics, and functional recovery in individuals undergoing gonarthrosis surgery.
- Trial name
- NCT07480473
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Medipol University
Total Knee Anthroplasty
Smart Knee Evaluation of Exparel and Zynrelef in TKA Recovery
This study looks at how three different numbing injections affect how quickly patients recover after knee replacement surgery (total knee arthroplasty, or TKA).
- Trial name
- NCT07878507
- Testing
- Intra-articular injection of bupivacaine in the knee joint, intra-articular injection of Exparel in the knee joint, Zynrelef
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Foundation for Orthopaedic Research and Education
Osteoarthritis
Does Intraoperative Intravenous Iron Enhance Postoperative Oxygenation Profile in Total Knee Arthroplasty Surgery?
The objective of the present study is to determine the impact of intraoperative IV-iron supplementation on postoperative oxygenation profile by comparing the postoperative PaO2/FiO2 ratio with or without IV-iron supplementation…
- Trial name
- NCT02544464
- Testing
- ferric carboxymaltose 1000 mg
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- Konkuk University Medical Center
Osteoarthritis, Degenerative Joint Disease
The Study of Physical Activity Rewards After Knee Surgery
The objectives of this research are to conduct a proof of concept randomized controlled trial with 200 patients undergoing primary total knee replacement (TKR) at Brigham and Women's Hospital (BWH).
- Trial name
- SPARKS (NCT01970631)
- Testing
- Motivational Interviewing (MI), Financial Incentives
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Brigham and Women's Hospital
Total Knee Arthroplasty, Total Knee Arthroplasty Recovery
Effects of Stress Ball Use and Breathing Exercises on Pain and Vital Signs During Drain Removal After Total Knee Arthroplasty
This randomized controlled trial aims to evaluate the effects of stress ball use and breathing exercises on procedural pain and vital signs during drain removal in patients undergoing total knee arthroplasty.
- Conditions
- Total Knee Arthroplasty, Total Knee Arthroplasty Recovery, Pain After Knee Arthroscop
- Trial name
- TDP (NCT07586436)
- Testing
- 3. Control Group Description, 1. Stress Ball Intervention Description, 2. Breathing Exercise Intervention Description
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Osteoarthritis, Knee
Outcome Comparison of Two Total Knee Arthroplasty Systems: e.Motion-Pro Versus Genesis II
Recently, E.Motion-PS-Pro (B.Braun-Aesculap, Tuttlingen, Germany), a new mobile bearing knee system with a unique ball and socket post-cam mechanism was developed for use in total knee arthroplasty.
- Trial name
- NCT02276118
- Testing
- device: e.motion PS Pro, device : Genesis II
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Seoul National University Hospital
Arthroplasty Complications
Safety of Total Knee Replacement Surgery Before and After the Implementation of Enhanced Recovery Program
The objectives are to describe the transition from traditional care to an enhanced recovery program for the management of total knee arthroplasty, and to evaluate the effect on patient outcomes.
- Trial name
- NCT05028426
- Testing
- Enhanced recovery program
- Where
- France
- Volunteers
- 455 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Surgery, Total Knee Arthroplasty
Enhanced Recovery After Surgery for Total Knee Arthroplasty, Left Colectomy and Hysterectomy
The objective of the study is to assess retrospectively the effect of an awareness-raising phase in favour of Enhanced Recovery After Surgery across the Assistance Publique-Hopitaux Paris institution and to explore the…
- Conditions
- Surgery, Total Knee Arthroplasty, Colectomy, Hysterectomy
- Trial name
- RAAC-AP (NCT03552913)
- Testing
- One year before awareness-raising phase in favour of Enhanced Recovery After Surgery, One year after awareness-raising phase in favour of Enhanced Recovery After Surgery, No specific program toward improving practices
- Where
- France
- Volunteers
- 1,710 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Total Knee Arthroplasty
Femoral Triangle and Adductor Canal Blocks Versus Femoral Nerve Block for Total Knee Arthroplasty
This prospective, double-blinded, randomized controlled study evaluates effects of femoral triangle and adductor canal blocks in comparison with femoral nerve block for primary total knee arthroplasty.
- Trial name
- NCT03645954
- Testing
- Femoral Nerve Block, Femoral Triangle & Adductor Canal Blocks
- Where
- Lithuania
- Volunteers
- 80 people
- Sponsor
- Lithuanian University of Health Sciences
Osteoarthritis
Home PT vs FORCE PT
The purpose of this study is to determine if unsupervised, home rehabilitation delivered by a web-based platform or paper manual is a safe and effective alternative to outpatient physical therapy after total knee replacement.
- Trial name
- NCT02911389
- Testing
- Home PT via web-based platform, Home PT via paper manual, outpatient PT
- Where
- United States
- Sponsor
- Rothman Institute Orthopaedics
Thromboembolic Events, Post-operative Bleeding
Frequency of Vascular Events With Short-term Thromboprophylaxis in Fast-track Hip and Knee-arthroplasty.
There are many different views regarding ideal duration and type of thromboprophylaxis after hip or knee surgery. An important factor in Fast-track surgery is early mobilization, which in itself is thought to prevent clotting.
- Trial name
- FETA (NCT01557725)
- Where
- 6 sites in Denmark
- Volunteers
- 4,924 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Primary Total Knee Arthroplasty
The Efficacy of Local Infiltration Analgesia for Postoperative Pain Management After Total Knee Arthroplasty
This prospective, double-blinded, randomized controlled study evaluates the effects of peripheral nerve blocks with and without local infiltration analgesia for postoperative pain management after primary total knee arthroplasty.
- Trial name
- NCT04258241
- Testing
- Local infiltration analgesia with local anesthetic, Local infiltration analgesia without local anesthetic, Needle
- Where
- Lithuania
- Volunteers
- 80 people
- Sponsor
- Lithuanian University of Health Sciences
Arthritis Knee
Functional Recovery After Total Knee Arthroplasty
The goal of this observational study is to learn about patients' recoveries after receiving total knee arthroplasty (TKA). The main questions it aims to answer are: Does robotic-assisted TKA have improved perceived recovery when…
- Trial name
- NCT06821269
- Testing
- Robotic assisted total knee arthroplasty, Manual total knee arthroplasty, Robotic assisted revision total knee arthroplasty
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
Surgical Stress Response, Stress Physiological
Feasibility of Breathwork Intervention With Older Adults After Knee Surgery
Postoperative complications after surgical procedures, including following total knee arthroplasty (TKA), have a negative impact on the health and well-being of surgical patients.
- Conditions
- Surgical Stress Response, Stress Physiological, Stress Physiology, Stress Psychological
- Trial name
- NCT07464860
- Testing
- A 5-minute Asynchronous Breathwork Intervention, A 5-minute Asynchronous Card Game Video
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Postoperative Outcomes Within an Enhanced Recovery After Surgery Protocol (POWER2)
Methods National audit of a 60-day prospective observational cohort in the that the pre-defined postoperative complications at 30 days of follow-up in adult patients electively undergoing hip replacement surgery (HRS) or knee…
- Trial name
- POWER2 (NCT03570944)
- Testing
- HRS, KRS
- Where
- Spain
- Volunteers
- 3,012 people
- Sponsor
- Grupo Español de Rehabilitación Multimodal