Clinical trials: Total Knee Replacement Surgeries
Arthropathy of Knee, Arthropathy of Hip
Results of the Application of the Clinical Pathway of Intensified Recovery Surgery for Adults in the Processes of Total Knee and Hip Replacement at the Maz Hospital
The investigators are going to study all the patients who have undergone surgery at the MAZ hospital from 2019 to the present for knee replacement and hip replacement.
- Trial name
- NCT05338255
- Where
- Spain
- Volunteers
- 534 people
- Sponsor
- Universidad de Zaragoza
Osteoarthritis, Osteoarthritis, Knee
The Effectiveness of Resistance Training for Patients With Degenerative Arthritis After Surgery
Osteoarthritis is a common degenerative disease that significantly impacts mobility and disability in older adults. This pilot randomized controlled study aimed to examine the effects of a three-month resistance training program…
- Trial name
- Arthritis (NCT07696195)
- Testing
- Progressive Lower Extremity Resistance Exercise, Routine Postoperative Rehabilitation Care
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Tzu Chi University
Osteoarthritis
Comparing Surgery Versus Standard Physical Therapy in Treating People With a Meniscal Tear and Osteoarthritis
There are two cartilage structures, called menisci, in each knee joint. A torn meniscus can be caused by a traumatic injury or aging-related degeneration.
- Trial name
- NCT00597012
- Testing
- Arthroscopic partial menisectomy, Standard physical therapy, Postoperative rehabilitative physical therapy
- Where
- 7 sites in United States
- Volunteers
- 351 people
- Sponsor
- Brigham and Women's Hospital
Arthritis Knee, Arthritis of Hip
Health Coaching for Patients Waiting for Total Hip or Knee Replacements
This pilot study aims to evaluate the feasibility of collecting objective data on physical performance to measure the impact of health coaching in addition to a digital resource (Active Wait) and enable sample size calculation…
- Trial name
- NCT06596031
- Testing
- Health coaching, Digital toolkit
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Sheffield Hallam University
Intraoperative Complications
The Effect of Therapeutic Touch Applied During Knee Replacement Surgery on Anxiety, Vital Signs and Comfort Level
The aim of this study is to investigate the effect of therapeutic touch on patients' anxiety, vital signs and comfort levels during knee replacement surgery performed under local anesthesia.
- Trial name
- NCT06426381
- Testing
- Therapeutic Touch
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Dilek GÜRÇAYIR
Osteoarthritis: Joint Replacement Surgery
Comparing Pain Relief Between Exparel® Injection vs. On-Q Catheter as the Postsurgical Analgesia Following Total Knee Arthroplasty (TKA)
The goal of this research project is to evaluate the effectiveness of a novel treatment to control pain after Total Knee Arthroplasty (TKA).
- Trial name
- NCT02739230
- Testing
- Exparel, On-Q pain intra-articular catheter
- Sponsor
- Rothman Institute Orthopaedics
Arthroplasty Replacement, Knee, Anesthesia Conduction
Migration Rate for Continuous Adductor Canal Block Catheters After Primary Total Knee Arthroplasty Surgery: a Comparison Between Two Insertion Techniques
Continuous adductor canal block (CACB) is becoming increasingly popular for providing postoperative analgesia following knee arthroplasties.
- Trial name
- ISAFExOOPS (NCT07681622)
- Testing
- ISAFE technique for adductor canal catheter insertion, OOPS technique
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Staphylococcal Infections
StaphVAX Immunogenicity and Safety in Orthopaedic Joint Surgery
Staphylococcus aureus (S. aureus) is the most common pathogen encountered in infections associated with orthopedic surgery. StaphVAX® is a bivalent S.
- Trial name
- NCT00211965
- Testing
- S. aureus Types 5 and 8 Capsular Polysaccharide Conjugate
- Where
- United Kingdom
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Nabi Biopharmaceuticals
Wound Infection
Compare Antimicrobial to Conventional Suture in Patients Receiving Primary Total Knee Replacement
Total knee replacement is now one of the most popular reconstructive procedures for the elderly people to regain their functional capacity and life quality.
- Trial name
- Vicryl-Plus (NCT02533492)
- Testing
- vicryl, Vicryl plus
- Where
- Taiwan
- Volunteers
- 102 people
- Sponsor
- Mel Shiuann-Sheng Lee
Adductor Canal Block, Total Knee Replacement Surgery
Coupling of IPACK Block With Adductor Canal Block Versus Adductor Canal Block Alone on Pain, Functional Recovery and Inflammatory Response After Knee Replacement
The aim of this study is to compare the Competency of coupling of IPACK Block with Adductor Canal Block versus Adductor Canal Block Alone on Postoperative Pain after total knee replacement as well as Functional Recovery and…
- Conditions
- Adductor Canal Block, Total Knee Replacement Surgery, Functional Recovery
- Trial name
- NCT07096375
- Testing
- Adductor Canal Block (ACB) + iPACK Block
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Arthropathy of Knee, Pain, Joint
Assessing if Cryoneurolysis Improves Prehabilitation and Decreases Pain After Surgery With Less Opioid Use in TKA Patients
This is a prospective, randomized control trial to evaluate the impacts of preoperative cryoneurolysis treatment on opioid consumption with prehabilitation and resulting postoperative functional improvement in patients undergoing…
- Conditions
- Arthropathy of Knee, Pain, Joint, Arthritis Knee, Opioid Use
- Trial name
- NCT03836313
- Testing
- iovera°
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Total Knee Arthroplasty
Why Are so Many Patients Dissatisfied With Knee Replacement Surgery? Exploring Variations of the Patient Experience
The goal of this research is to fill the knowledge gap relating to why up to 20 percent of total knee arthroplasty (TKA) patients are dissatisfied with their clinical outcomes and to answer the research question: What are the…
- Trial name
- NCT01466920
- Where
- 7 sites in Canada
- Volunteers
- 515 people
- Sponsor
- University of British Columbia
Total Knee Replacement Surgery
Comparison of 3 Techniques for Ultrasound-guided Femoral Nerve Catheter Insertion
This is a randomized study which will compare three femoral nerve catheter insertion techniques. Subjects will be randomized into one of thee groups, Group 1: ultrasound guided femoral nerve catheter using a stimulation needle…
- Trial name
- NCT00927368
- Testing
- ultrasound guidance alone, ultrasound guidance and needle stimulation, ultrasound guidance and catheter stimulation
- Where
- United States
- Volunteers
- 453 people
- Sponsor
- The Cleveland Clinic
Postoperative Pain, Acute
The Effect of Adding an IPACK Block to the Adductor Canal Block on Total Knee Arthroplasty Surgery
Total knee arthroplasty (TKA) is a frequently performed major orthopedic surgery, where most patients experience severe postoperative pain.
- Trial name
- NCT06586840
- Testing
- rescue analgesia, Adductor Canal Block, Adding an IPACK Block to the Adductor Canal Block
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Anticoagulation
Multi-center Study to Evaluate the Safety of Apixaban (BMS-562247) in Indian Subjects Undergoing Elective Total Knee Replacement or Total Hip Replacement Surgery
The primary purpose of this protocol is to evaluate the safety of Apixaban in prophylaxis of Venous Thromboembolism (VTE) in Indian patients undergoing elective total knee or hip replacement
- Trial name
- NCT01884337
- Testing
- Apixaban
- Where
- 20 sites in India
- Volunteers
- 557 people
- Sponsor
- Bristol-Myers Squibb
Epidural; Analgesia, Local Infiltration
Comparison of Epidural Analgesia With Intra-Articular Infiltration Analgesia
The results of combining infiltrative analgesia applied by orthopedists with epidural analgesia applied by anesthesiologists after knee replacement surgery will be compared.
- Trial name
- NCT06872528
- Testing
- Recording the amount of medication and the number of complications according to observational follow-up
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Drainage
Evaluating the Effectiveness of 2 Surgical Skin Preparation Methods in Reducing Surgical Wound Drainage After Total Hip or Knee Replacement
Surgical skin complications can be costly and could contribute to extended in-patient stay following total joint replacement or even the need for re-admission.
- Trial name
- NCT01097135
- Testing
- Duraprep Surgical Solution
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Rothman Institute Orthopaedics
Total Knee Arthroplasty, Postoperative Nausea and Vomiting
ERAS-Based Preoperative Nutrition and Fasting in Total Knee Arthroplasty
The aim of this randomized controlled study is to investigate the effect of implementing a preoperative nutrition education and fasting protocol prepared in accordance with Enhanced Recovery After Surgery (ERAS) guidelines during…
- Trial name
- NCT07336160
- Testing
- ERAS-Based Preoperative Nutrition Education and Fasting Protocol, Standard Preoperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Nermin Ocaktan
Osteoarthritis, Knee
Dual-task Gait Performance in People With Knee Osteoarthritis Before and After Knee Replacement Surgery
Knee Osteoarthritis (OA) is one of the most common conditions causing disability and limitation in the elderly population, with 13% of women and 10% of men over the age of 60 suffering from symptomatic knee osteoarthritis.
- Trial name
- NCT04877873
- Testing
- Gait analysis pre- and post- surgery
- Where
- Israel
- Volunteers
- 38 people
- Sponsor
- University of Haifa
Osteoarthritis, Osteoarthritis (OA) of the Knee
Feasibility of Choose to Move Replacement Ready
Choose to Move (CTM) is a 3-month, choice-based health-promoting program for low active older adults being scaled-up across British Columbia (BC), Canada.
- Conditions
- Osteoarthritis, Osteoarthritis (OA) of the Knee, Osteoarthritis, Hip, Total Knee Arthroplasty; Total Hip Arthroplasty
- Trial name
- CTM-RR (NCT07069179)
- Testing
- Choose to Move Replacement Ready
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia