Clinical trials: Total Knee Replacement Surgery, active
Pain Management, Arthroplasty
Effect of Preoperative Pain Education on Anxiety, Pain, and Analgesic Use in Total Knee and Hip Replacement Patients
This randomized controlled trial evaluates whether a standardized preoperative pain education session delivered by a nurse reduces postoperative pain intensity and surgical anxiety among adult elective orthopedic surgery patients…
- Conditions
- Pain Management, Arthroplasty, Knee Replacement, Hip Replacement
- Trial name
- Pain-Anxiety (NCT07362589)
- Testing
- Pain education
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Yeditepe University
Stress
Effect of Audio Book applıcatıon on patıents Blood Pressure, Pulse Rate and anxıety Levels Before Total Knee Replacement Surgery
Before the TDP surgery, the anxiety levels of the patients in the experimental group will be measured by listening to an audio book.
- Trial name
- NCT06905899
- Testing
- audiobook app
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Beyza Yilmaz
Postoperative Outcomes, Postoperative Complications
The Effect of Perioperative Nutritional Care on Recovery After Knee and Hip Replacement Surgery
This prospective observational study will assess the impact of standardized perioperative nutritional care on postoperative outcomes in patients undergoing elective total hip (THA) or knee arthroplasty (TKA) at the First…
- Conditions
- Postoperative Outcomes, Postoperative Complications, Length of Hospital Stay
- Trial name
- NCT06989229
- Where
- Czechia
- Volunteers
- 1,000 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Knee Osteoarthritis, Replacement, Knee
Exploration of Appropriate BIS Range and Propofol Effect-site Concentration During Total Intravenous Anesthesia With Concomitant Adjuvants.
The goal of this clinical trial is to determine the appropriate Bispectral Index (BIS) range and propofol effect-site concentration required to maintain adequate anesthesia depth during total intravenous anesthesia (TIVA)…
- Conditions
- Knee Osteoarthritis, Replacement, Knee, Elective Surgical Patients, ASA Class I/II Patients
- Trial name
- NCT07736352
- Testing
- Propofol + Remifentanil +Midazolam, Propofol + Remifentanil + Dexmedetomidine, Propofol + Remifentanil + Esketamine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- China-Japan Friendship Hospital
Total Knee Arthroplasty
Effectiveness of Exparel Anesthetic Administered by the Surgeon During Knee Surgery
Intra-articular Posteromedial Surgeon Administered (IPSA) Block in this study describes a new type of medical procedure where a surgeon provides anesthetic medication directly into a specific area inside a knee joint to numb the…
- Trial name
- NCT06946368
- Testing
- Intra-articular Posteromedial Surgeon Administered (IPSA) Block of EXPAREL, Adductor Canal Block (ACB) and Local Local Infiltration Analgesia of EXPAREL, Local Infiltration Analgesia (LIA) of EXPAREL
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Cleveland Clinic
Knee Osteoarthritis
SII Levels Following iPACK Block With Adductor Canal Block in Knee Arthroplasty
This randomized controlled trial evaluates the effect of ultrasound-guided iPACK block with Adductor Canal Block (ACB) on the Systemic Immune-Inflammation Index (SII) in elderly patients undergoing total hip arthroplasty under…
- Trial name
- NCT07449442
- Testing
- sodium Chloride, Ropivacaine Hydrocloride
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Aseptic Revision Knee Arthroplasty, Stiffness Following Revision Knee Arthroplasty
Does Joint Immobilization Following Revision Total Knee Arthroplasty Improve Range of Motion Following Surgery?
The goal of this study is to evaluate if knee immobilization for 10 days following revision total knee arthroplasty (rTKA) improves knee joint range of motion at 3 months postoperatively compared to standard of care postoperative…
- Trial name
- NCT07552415
- Testing
- Knee immobilizer, No Knee Immobilizer
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Hospital for Special Surgery, New York
Knee Osteoarthritis
Robotic Assisted Surgery In Total Knee Replacement
The goal of this clinical trial is to compare robotic arm assisted surgery with manual surgery in patients operated with knee replacement.
- Trial name
- NCT05842538
- Testing
- Triathlon
- Where
- 2 sites in Sweden
- Volunteers
- 200 people
- Sponsor
- Sahlgrenska University Hospital
Osteoarthritis, Knee, Osteoarthritis, Hip
Promoting Sleep to Alleviate Pain - Arthroplasty
PROSAP-A is a perioperative randomized, controlled trial with a 12-month follow-up period after total knee arthroplasty (TKA) or total hip arthroplasty (THA), aiming to investigate both acute and long-term postoperative effects…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Insomnia, Surgery
- Trial name
- PROSAP-A (NCT06145516)
- Testing
- Cognitive behavioral therapy for insomnia (CBT-I), Sleep education therapy (SET)
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Uppsala University
Knee Arthropathy
Virtual Rehabilitation Platform for Patients With Knee Prothesis
This clinical trial aims to evaluate the effectiveness and usability of the Trak Rehabilitation Platform in patients who have undergone knee replacement surgery.
- Trial name
- NCT06720779
- Testing
- TRAK physio knee prosthesis protocol, Knee conventional rehabilitation program
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Trak Health Solutions S.L.
Anesthesia
Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service
A comparison of two anesthetic techniques for total knee replacements: (1) Peri-Articular Injection (PAI), local infiltration between the popliteal artery and capsule of the knee block (IPACK) and single-shot adductor canal block…
- Trial name
- EKAT-TeleTPS (NCT03747146)
- Testing
- Continuous Adductor Canal Catheter (ACC)
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Knee Arthroplasty, Total
The Effect of Tele-Consultation Supported Education After Total Knee Arthroplasty Surgery
Following total knee arthroplasty, patients may encounter numerous problems that can hinder the performance of daily living activities, negatively impact quality of life, and increase morbidity and mortality rates.
- Trial name
- NCT06784596
- Testing
- Teleconsulting supported training
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Turgut Sohret
Acute Postoperative Pain, Surgery
Continuous Versus Single Injection Adductor Canal Blocks for Outpatient Total Knee Arthroplasty
This is a single-center pilot study to determine if an adductor canal continuous nerve block is superior to single injection nerve block following total knee arthroplasty.
- Trial name
- NCT06784882
- Testing
- continuous peripheral nerve block with OnQ pump, single injection nerve block
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Diego
Arthroplasty, Replacement, Knee, Blood Loss, Surgical
Early Outcome of Simultaneous Bilateral Total Knee Replacement With and Without Tourniquet
This randomized controlled trial compared early outcomes after replacement of both knees during the same operation, with and without tourniquet use.
- Conditions
- Arthroplasty, Replacement, Knee, Blood Loss, Surgical, Pain, Postoperative
- Trial name
- NCT07905495
- Testing
- Simultaneous Bilateral Total Knee Replacement with Tourniquet, Simultaneous Bilateral Total Knee Replacement without Tourniquet
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- Shifa International Hospital
Osteoarthritis of the Knee or Hip
Comparison Between Blocks or Not in Joint Arthroplasty
The purpose of this study is to evaluate the effect on postoperative pain, opioid consumption and function by adding a combination of regional blocks with local anaesthetic before total hip- and knee arthroplasty compared to…
- Trial name
- BLAST (NCT06230081)
- Testing
- Ropivacain 5 mg/ml + Clonidine
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Region Skane
Knee Osteoarthritis
Clinical Outcome After Total Knee Arthroplasty Using CR or PS Inlay
Compare knee flexion after cruciate-retaining and cruciate substituting Total Knee Arthroplasty.
- Trial name
- NCT03873363
- Testing
- PS TKA, CR TKA
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Technische Universität Dresden
Arthroplasty Replacement, Knee, Anesthesia Conduction
Migration Rate for Continuous Adductor Canal Block Catheters After Primary Total Knee Arthroplasty Surgery: a Comparison Between Two Insertion Techniques
Continuous adductor canal block (CACB) is becoming increasingly popular for providing postoperative analgesia following knee arthroplasties.
- Trial name
- ISAFExOOPS (NCT07681622)
- Testing
- ISAFE technique for adductor canal catheter insertion, OOPS technique
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Knee Replacement, Total, Knee Replacement Surgery
Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine in Spinal Anaesthesia
Prilocaine numbs you for a shorter time, allowing you to regain movement quicker, which helps you recover faster, start rehab sooner, and feel more satisfied with your treatment overall.
- Trial name
- NCT07329582
- Testing
- prilocaine, Bupivacaine
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- National University Hospital, Singapore
Total Knee Replacement Surgery, Post-operative Pain
Suzetrigine for Treatment and Reduction of Intense Discomfort After knEe Replacement PAIN
This is a prospective, randomized study. The purpose of this study is to evaluate if the addition of Suzetrigine, a new pain medication, to well established peri-operative pain regimen used for total knee replacement surgery will…
- Trial name
- STRIDE-PAIN (NCT07548385)
- Testing
- Suzetrigine
- Where
- United States
- Volunteers
- 235 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Rehabilitation Exercise
Evaluating the Efficacy of a "Quiet Knee Protocol" in Primary Total Knee Arthroplasty (TKA): A Prospective Randomized Study
The goal of this randomized clinical trial is to access the following: 1. Compare the effectiveness of the QKP versus a standard rehabilitation protocol in improving postoperative pain control, ROM, and functional recovery…
- Trial name
- QKP (NCT07879014)
- Testing
- Quiet Knee Protocol, Post Operative Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 170 people
- Sponsor
- Mayo Clinic