Clinical trials: Total Knee Replacements
Total Knee Replacement
Clinical and Functional Outcome of the Gemini SL Fixed Bearing at Midterm Follow-up
This is a retrospective, multicenter case series with a prospective follow-up to confirm the safety and performance of the Gemini SL Fixed Bearing knee prosthesis in midterm follow-up under routine conditions.
- Trial name
- NCT03575546
- Where
- 3 sites in Germany, Spain
- Volunteers
- 254 people
- Sponsor
- Waldemar Link GmbH & Co. KG
Osteoarthritis (OA) of the Knee
Impact of Blood-Flow-Restriction Prehabilitation on Pre- and Postoperative Rehabilitation After Total Knee Arthroplasty
Degenerative and traumatic diseases of the musculoskeletal system lead to increased immobility of a patient, which in turn results in muscle atrophy.
- Trial name
- NCT06964022
- Testing
- BFR
- Where
- Germany
- Volunteers
- 19 people
- Sponsor
- University Hospital, Bonn
TKA, Knee Osteoarthritis
Wearable Electrogoniometry-Based Telerehabilitation After Total Knee Arthroplasty
This study evaluated a wearable electrogoniometry-based telerehabilitation system designed to support recovery after total knee arthroplasty.
- Trial name
- NCT07779122
- Testing
- Wearable Electrogoniometry-Based Telerehabilitation System, Standard Home-Based Rehabilitation Program
- Where
- Chile
- Volunteers
- 82 people
- Sponsor
- University of Chile
Total Knee Replacements
Analgesic Effect of Adding an Adductor Canal Block to a Femoral Triangle Block for Total Knee Replacement
The aim of the study is to investigate whether the addition of an adductor canal block to a femoral triangle block will provide better analgesia for patients after total knee replacements.
- Trial name
- NCT03461679
- Testing
- Adductor canal block, Femoral triangle block
- Where
- Singapore
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Changi General Hospital
Total Knee Arthroplasty, Rehabilitation
Effect of Fast Inpatient Rehabilitation After TKA
Rehabilitation is an important part of the post-operative treatment after TKA by consensus. This study intends to analysis whether fast inpatient rehabilitation after TKA can improve knee joint or general function, and ultimately…
- Trial name
- NCT04458480
- Testing
- Fast Inpatient Rehabilitation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Arthroplasties, Knee Replacement, Revision Arthroplasty
Patient Outcomes With Robotic-Assisted Total Knee Arthroplasty
This is a post-market multicentre study that has been implemented to confirm safety and performance of cemented CR/UC and PS Apex Knee implants in primary or revision Robotic Assisted Total Knee Arthroplasty up to 10-year follow…
- Trial name
- NCT06203756
- Testing
- Omnibotics Robotic-assisted Total Knee Arthroplasty with Apex UC, Omnibotics Robotic-assisted Total Knee Arthroplasty with Apex PS, Omnibotics Robotic-assisted Total Knee Arthroplasty with Apex Revision
- Where
- 6 sites in United States
- Volunteers
- 713 people
- Sponsor
- Corin
Pain, Postoperative, Arthroplasty, Replacement, Knee
Intrathecal Morphine in Knee Arthroplasty
This study is designed to explore the efficacy lower doses of intra-spinal morphine for pain relief and side effect profiles of same in the setting of Total Knee Replacement.We hypothesized that a dose greater than that used in…
- Trial name
- NCT00695045
- Testing
- intra thecal morphine
- Volunteers
- 60 people
- Sponsor
- University College Hospital Galway
Total Knee Arthroplasty
Acute Effects of Strengthening Lower Limbs Operated by Total Knee Arthroplasty
Knee osteoarthritis is a chronic joint disease and one of the leading causes of disability among adults, resulting in irreversible damage to articular cartilage and subchondral bone, osteophyte formation, joint pain and…
- Trial name
- AESLLKNEE (NCT05444400)
- Testing
- Strengthening, Conventional protocol
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Valencia
Osteoarthritis, RheumatoId Arthritis
Zimmer POLAR - Total Knee Arthroplasty (TKA)
The primary objective of this study is to obtain implant survivorship and clinical outcomes data for commercially available Persona fixed bearing knee implants used in total knee arthroplasty.
- Conditions
- Osteoarthritis, RheumatoId Arthritis, Traumatic Arthritis, Polyarthritis
- Trial name
- NCT01859130
- Testing
- Zimmer Persona Total Knee System
- Where
- 4 sites in United States
- Volunteers
- 299 people
- Sponsor
- Zimmer Biomet
Osteoarthritis
Evaluation of Short-term Effects of Tourniquet Use in Different Ways During Total Knee Arthroplasty
To study the short-term effects of tourniquet use in different ways in total knee arthroplasty,60 patients were randomly divided into 2 groups (30 cases/group): group A using the tourniquet throughout the operation, and group B…
- Trial name
- NCT02102581
- Testing
- short time tourniquet
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking Union Medical College Hospital
Total Knee Arthroplasty
Saphenous Nerve Block Versus Femoral Nerve Block for Total Knee Arthroplasty
Currently, the regional anesthetic standard of care for total knee replacement surgery is combined spinal/epidural, with or without a femoral nerve block, or FNB.
- Trial name
- NCT01333943
- Testing
- Study Group: Experimental, Control Group
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Hospital for Special Surgery, New York
Total Knee Arthroplasty
IO Vancomycin Administration in TKA
This is a prospective, single-center, open-label study evaluating systemic vancomycin levels following preoperative intraosseous administration in patients undergoing primary unilateral total knee arthroplasty.
- Trial name
- IO Vanco (NCT07633418)
- Testing
- Intraosseous Vamcomycin Administration
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Diego
Knee Arthroplasty, Total, Peripheral Nerve Block
Postoperative Analgesia in Bilateral Knee Arthroplasties
To observationally compare the analgesic efficacy of LIA and S-FICB techniques and to record the pain scores of patients who underwent bilateral knee operations in the postoperative period.
- Conditions
- Knee Arthroplasty, Total, Peripheral Nerve Block, Pain, Postoperative
- Trial name
- NCT06357013
- Testing
- Bilateral Suprainguinal fascia iliaca compartment block, Local infiltration analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Total Knee Arthroplasty, Osteoarthritis
Electrical Stimulation After Total Knee Arthroplasty
Total knee arthroplasty (TKA) is performed more than 300,000 times a year in the United States, most often for osteoarthritis (OA).
- Trial name
- NCT00224913
- Testing
- Neuromuscular electrical stimulation, Voluntary exercise
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Total Knee Arthroplasty (Replacement)
A Study on the Physiological Outcomes of the Enhanced Recovery After Surgery Model in Older Adults Undergoing Total Knee Arthroplasty
With the advent of an aging society, the demand for total knee arthroplasty (TKA) continues to increase. Postoperative recovery is influenced not only by the surgical procedure itself but also by pain control, joint function, and…
- Trial name
- NCT07828418
- Testing
- Enhanced Recovery After Surgery (ERAS) Care Pathway, Usual Perioperative Care
- Volunteers
- 60 people
- Sponsor
- China Medical University Hospital
Knee Osteoarthritis
TKA Using Patient-Specific Instrumentation
The purpose of our study is to determine if anatomic/kinematic total knee arthroplasties (TKAs) are superior to mechanical axis-referenced TKAs with respect to determinants of gait functionality, patient satisfaction and other…
- Trial name
- NCT03117959
- Testing
- Stryker ShapeMatch Technology, Stryker Triathlon Custom Fit Knee
- Where
- Canada
- Sponsor
- Queen's University
Arthroplasty, Replacement, Knee, Recovery of Function
The Influence of Rapid Recovery on Sleep Quality Following Total Knee Replacement Surgery
The purpose of this study is to evaluate the influence of rapid recovery on sleep quality following total knee replacement surgery.
- Conditions
- Arthroplasty, Replacement, Knee, Recovery of Function, Arthritis, Rheumatoid
- Trial name
- NCT02845960
- Testing
- rapid recovery
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Southwest Hospital, China
Knee Arthroplasty, Total, Telerehabilitation
Action Observation Therapy Via Telerehabilitation on Total Knee Arthroplasty Surgery
The goal of this clinical trial is to compare patient-reported and performance-based outcomes of patients followed with a standard exercise program based on telerehabilitation and patients followed with action observation therapy…
- Trial name
- NCT06162208
- Testing
- Standard exercise program based on telerehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Pamukkale University
Osteoarthritis, Knee
Stryker Triathlon® Cruciate Substituting vs. Posterior Stabilized Outcomes Study
This study compares the clinical and radiographic outcomes obtained with the use of the Stryker Triathalon® Cruciate Substituting (CS) and Posterior Stabilized (PS) tibial inserts.
- Trial name
- NCT01367925
- Testing
- Stryker Triathlon® CS Tibial Insert, Stryker Triathlon® PS Tibial Insert
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Spokane Joint Replacement Center
Post-op Pain
Adductor Canal Nerve Block Following Total Knee Arthroplasty
The purpose of this study is that an adductor canal nerve block (putting numbing medicine near the nerve) has been shown to produce excellent pain relief with less pain medication use after knee replacement surgery.The…
- Trial name
- NCT01939379
- Testing
- Morphine PCA started at the end of surgery, 1 Percocet 1/325mg every 4 hours; may receive a second Percocet if needed., For the 30ml ropivacaine the intervention would be the subject can request extra pain medication which would be Percocet and/or morphine PCA.
- Where
- United States
- Sponsor
- Loma Linda University