Clinical trials: Total Laparoscopic Hysterectomy
Postoperative Pain
Efficacy of Modified Thoracoabdominal Nerves Block Through Perichondrial Approach in Total Laparoscopic Hysterectomies
TAPA is a new analgesic block technique that involves the injection of local anesthetics into the thoracoabdominal nerves using a perichondrial approach.
- Trial name
- NCT06116409
- Testing
- Bupivacain
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Pain, Postoperative, Anesthesia
Transversus Abdominal Plane Block at Total Laparoscopic Hysterectomy: Effect on Quality of Recovery
The Transversus Abdominal Plane (TAP) block has been used with good success to decrease postoperative pain following laparatomy.
- Trial name
- TAP (NCT01479270)
- Testing
- TAP Block
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Total Laparoscopic Hysterectomy With Myoma Screw
Myoma Screw in Manipulation of Large Uterus in Total Laparoscopic Hysterectomy
To compare between myoma screw and uterine manipulator in manipulation of large uterus in total laparoscopic hysterectomy
- Trial name
- NCT06976905
- Testing
- Total laparoscopic hysterectomy
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Patient Engagement
Virtual and Video Counseling Versus In-Office Counseling for Laparoscopic Hysterectomy
Compare preparedness for total laparoscopic hysterectomies between patients who undergo virtual visits and those who undergo in-office visits for pre-operative counseling.
- Trial name
- NCT05086406
- Testing
- Combination of Video and Virtual Pre-operative Counseling
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Hysteromyoma
Total Laparoscopic Hysterectomy vs Minilap Hysterectomy
The objective of this study is to compare the perioperative outcomes between mini-lap hysterectomy and total laparoscopic hysterectomy (TLH) because of benign indications.
- Trial name
- NCT03251677
- Testing
- Surgical procedure, Hysterectomy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Vaginal Vault Prolapse, Sexual Function
Prophylactic Modified McCall Culdoplasty During Total Laparoscopic Hysterectomy
The purpose of this study is to assess the feasibility of performing prophylactic McCall culdoplasty at the time of total laparoscopic hysterectomy.
- Trial name
- NCT01840176
- Testing
- McCall culdoplasty
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Lidocaine, Dexmedetomidine
Effect of Co-administration Lidocaine and Dexmedetomidine on Quality of Recovery
BACKGROUND: Some studies have revealed that intravenous (IV) lidocaine or dexmedetomidine might improve the quality of recovery undergoing laparoscopic surgery.
- Conditions
- Lidocaine, Dexmedetomidine, Quality of Recovery(QoR-40), Preoperative and Postoperative
- Trial name
- NCT04706767
- Testing
- Co-administration Lidocaine and Dexmedetomidine, Dexmedetomidine infusion, Lidocaine infusion
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Anqing Municipal Hospital
Gynecologic Diseases
Laparoscopic Supracervical Hysterectomy Versus Total Laparoscopic Hysterectomy
The purpose of this research study is to evaluate whether there is any difference in recovery time and return to normal activities following a laparoscopic supracervical hysterectomy (LSH) compared with total laparoscopic…
- Trial name
- NCT00734812
- Testing
- Laparoscopic supracervical hysterectomy, Total laparoscopic hysterectomy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Laparoscopic Surgical Procedure, Obesity
Previous Abdominal Surgery and Obesity Does Not Affect Unfavorably the Outcome of Total Laparoscopic Hysterectomy
Previous surgery and obesity has disputed as an unfavorable factor during Total Laparoscopic Hysterectomy. The aim of the investigator's study was to assess the effects of previous abdominal surgery and obesity on intra-operative…
- Conditions
- Laparoscopic Surgical Procedure, Obesity, Surgery--Complications
- Trial name
- NCT03738085
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Ankara University
Operative Time, Length of Hospital Stay
VCare Versus SecuFix Uterine Manipulator for Total Laparoscopic Hysterectomy
Hysterectomy, the most commonly performed gynecological operation, can be carried out through various methods using a wide array of instruments and energy techniques.
- Conditions
- Operative Time, Length of Hospital Stay, Perioperative Complications
- Trial name
- NCT06398769
- Testing
- SecuFix UM, VCare UM
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Surgery, Gynecologic Disease
Study Evaluating the Success Rate of Outpatient Management of the Total Benign Hysterectomy by Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) Compared to Each of the Two Laparoscopic Routes (Conventional and Robot-assisted).
Benign total hysterectomy is one of the most commonly performed gynecological surgery. Conventionally performed by a classical surgical approach, it is now provided routinely and for several years by laparoscopy and more recently…
- Trial name
- HYSTERAMBU (NCT06471049)
- Testing
- Benign Hysterectomy
- Where
- France
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Elsan
Pain, Postoperative
Multimodal Pain Management After Robotic-Assisted Total Laparoscopic Hysterectomy
Hysterectomy is the most common major gynecologic surgery performed in the US and is performed for a variety of indications including malignancy, pelvic mass, endometriosis, leiomyoma, and pelvic organ prolapse.
- Trial name
- RA-TLH (NCT04429022)
- Testing
- Gabapentin, Acetaminophen, Celecoxib
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Preventative Laparoscopic Hysterectomy
Chlorhexidine vs Povidone Iodine Vaginal Prep in Decreasing Postoperative Infection in Total Laparoscopic Hysterectomy
This is a randomized control trial which will randomize patients who will be undergoing laparoscopic (conventional or robotic assisted) total hysterectomy to vaginal prep with 4% chlorhexidine gluconate vs 10% povidone iodine.
- Trial name
- NCT05692986
- Testing
- A vaginal swab for aerobic and anaerobic cultures before antibiotic administration, 30 minutes after vaginal prep and every hour thereafter until the surgery is completed.
- Volunteers
- healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Surgical Wound Dehiscence
Vaginal Cuff Dehiscence at Total Laparoscopic Hysterectomy
The aim of this study is to assess a major complication of total laparoscopic hysterectomy, vaginal dehiscence, with two different colpotomy techniques.
- Trial name
- NCT02879487
- Testing
- Monopolar needle electrode
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ankara University
Inflammation, Hospital Stay
Neutrophil to Lymphocyte Ratio (NLR) and Platelet to Lymphocyte Ratio (PLR) as an Inflammatory Markers to Predict Length of Hospital Stay After Total Laparoscopic Hysterectomy (TLH) for Benign Indications
Due to short hospital stay, rapid return to work, less pain, and good cosmetic results, laparoscopic hysterectomy ( LH) has substantially increased the era of hysterectomy procedures especially for the last two decades.
- Conditions
- Inflammation, Hospital Stay, Total Laparoscopic Hysterectomy
- Trial name
- NCT05003297
- Testing
- hemogram inflammatory parameters
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Hysterectomy, Laparoscopy
Tolerance of the vNOTES Surgical Technique in Total Hysterectomy for Benign Lesion. Clinical Trial of Non-inferiority Compared to the Laparoscopic Technique.
During a first consultation with an indication of total hysterectomy for a benign lesion, we will study the patient's eligibility.
- Conditions
- Hysterectomy, Laparoscopy, vNOTES
- Trial name
- VLAP (NCT05031182)
- Testing
- Laparoscopy, vNOTES
- Where
- 2 sites in France
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Postoperative Care, Pain Management
Effectiveness of Curcuminoids in Controlling Postoperative Pain Following Total Laparoscopic Hysterectomy
Total hysterectomy is one of the most common surgical procedures in gynecology. Total laparoscopic hysterectomy (TLH) has several advantages over open surgery, such as better cosmetic outcomes, faster recovery, and an earlier…
- Trial name
- NCT06886035
- Testing
- liposomal curcumin
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Uterine Fibroids, Abnormal Uterine Bleeding
Does 3D Laparoscopy Improve Vaginal Cuff Suture Time?
The objective aim is to evaluate whether the use of 3D laparoscopy facilitates the vaginal cuff closure of the vaginal cuff during a total laparoscopic hysterectomy among novice laparoscopists (PGY 2-4, Fellow).
- Conditions
- Uterine Fibroids, Abnormal Uterine Bleeding, Pelvic Pain, Adenomyosis
- Trial name
- 3DRCT (NCT02192606)
- Testing
- Storz 3D Laparoscopy System, 2D Laparoscopy
- Where
- 2 sites in United States, Denmark
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Abnormal Uterine Bleeding, Uterine Bleeding
Outcomes on Abdominal Versus Vaginal Morcellation At Time of Hysterectomy
The purpose of the study is to investigate differences in perioperative and postoperative outcomes between the abdominal (AM) versus vaginal (VM) routes of contained morcellation in participants undergoing laparoscopic total…
- Conditions
- Abnormal Uterine Bleeding, Uterine Bleeding, Fibroid Uterus, Surgery
- Trial name
- NCT04434066
- Testing
- Total Laparoscopic Hysterectomy
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Post-operative Pain
Presacral Nerve Block Versus Sham Block on Post-operative Pain for Total Laparoscopic Hysterectomy
The study is a single-center parallel group randomized controlled trial comparing the administration of a presacral nerve block using 20mL of local ropivacaine 5.0mg/ml versus 20mL of normal saline (sham block) on post-operative…
- Trial name
- NCT05953766
- Testing
- Ropivacaine injection, Normal saline injection
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada