Clinical trials: Total Occlusion of Coronary Artery
Coronary Artery Disease, Coronary Artery Bypass Grafting
Total Arterial Revascularization (TAR)
Total arterial revascularisation with in-situ confihuration of BITA is superior than y-graft in patients underwent CABG.
- Trial name
- NCT03753048
- Testing
- Y-Graft, In-Situ
- Where
- Russia
- Volunteers
- 880 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Chronic Total Occlusion of Coronary Artery
A Prospective, First in Man Study to Evaluate the Safety and Performance of the NovaCross™ Micro-catheter
This is a prospective, non-randomized, first-in-man investigational study, to assess the safety and technical feasibility, deployment and withdrawal characteristics of the NovaCross™ micro-catheter during an interventional…
- Trial name
- NCT01978860
- Testing
- NovaCross, CTO
- Where
- Israel
- Volunteers
- 2 people
- Sponsor
- Chanan Schneider
Ischemic Heart Disease (IHD)
XTR003 PET Radiotracer for the Detection of Viable Myocardium
The study was designed to explore the clinical feasibility of XTR003, a PET myocardial fatty-acid tracer, for the detection of viable myocardium in patients with ischemic heart disease (IHD).
- Trial name
- NCT05885854
- Testing
- XTR003
- Where
- China
- Volunteers
- 51 people
- Sponsor
- Sinotau Pharmaceutical Group
Chronic Total Occlusion of Coronary Artery, Vascular Disease
XIENCE V® USA Dual Antiplatelet Therapy (DAPT) Cohort
XIENCE V USA is a prospective, multi-center, multi-cohort postapproval study. The objectives of this study are To evaluate XIENCE V EECSS continued safety and effectiveness during commercial use in real world settings, and To…
- Conditions
- Chronic Total Occlusion of Coronary Artery, Vascular Disease, Myocardial Ischemia, Coronary Artery Stenosis
- Trial name
- XVU-AV DAPT (NCT01106534)
- Testing
- clopidogrel + aspirin OR prasugrel + aspirin, XIENCE V Everolimus Eluting Coronary Stent System (XIENCE V EECSS)
- Where
- 144 sites in United States
- Volunteers
- 870 people
- Sponsor
- Abbott Medical Devices
Chronic Total Occlusion of Coronary Artery
A Prospective, Multi-Center, Pivotal Study to Evaluate the Safety and Effectiveness of the NovaCross™ Micro-catheter in Facilitating Crossing Chronic Total Occlusion (CTO) Coronary Lesions
This study evaluates the safety and effectiveness of the a novel device called NovaCross to help cross Chronic Total Occlusion (CTO) lesions in coronary arteries.
- Trial name
- NCT02477579
- Testing
- NovaCross
- Where
- 5 sites in United States, Poland
- Volunteers
- 145 people
- Sponsor
- Nitiloop Ltd.
Coronary Artery Disease, Chronic Total Occlusions
Prognostic Impact of Chronic Total Occlusions
The purpose of this study is to determine the prognostic impact of the presence of chronic total occlusions (CTO) of the coronary arteries in patients undergoing coronary angiography and PCI.
- Trial name
- NCT02084888
- Where
- Sweden
- Volunteers
- 91,154 people
- Sponsor
- Sahlgrenska University Hospital
Ischemic Heart Disease, Chronic Total Occlusion of Coronary Artery
ISCHEMIA-CTO Trial - Revascularisation or Optimal Medical Therapy of CTO
Study design Prospective randomized open labeled multicenter study Hypotheses 1. In asymptomatic patients with ≥ 10% of myocardial ischemia: PCI (Percutaneous Coronary Intervention) with latest generation of drug eluting stents…
- Trial name
- ISCHEMIA-CTO (NCT03563417)
- Testing
- Percuteneous Coronary Intervention, Optimal Medical Therapy
- Where
- 27 sites in Denmark, Estonia and 5 more
- Volunteers
- 1,560 people
- Sponsor
- Aarhus University Hospital Skejby
Coronary Artery Disease (CAD), Chronic Total Occlusion (CTO)
EXPERT CTO: Evaluation of the XIENCE PRIME™ LL and XIENCE Nano™ Everolimus Eluting Coronary Stent Coronary Stents, Performance, and Technique in Chronic Total Occlusions
A prospective, multi-center, single-arm study to establish the safety and effectiveness of the XIENCE V® Everolimus Eluting Coronary Stent, XIENCE nano™ Everolimus Eluting Coronary Stent, XIENCE PRIME™ LL Everolimus Eluting…
- Trial name
- EXPERT CTO (NCT01435031)
- Testing
- CTO Treatment Device
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Abbott Medical Devices
Coronary Artery Disease, Postoperative Complications
Anesthesia Management of Coronary Artery Bypass Surgery and Inflammatory Biomarkers
The goal of this observational study is to evaluate effect of total intravenous anesthesia or inhalation anesthesia on inflammatory biomarkers in coronary artery bypass surgery and their relationship with early postoperative…
- Conditions
- Coronary Artery Disease, Postoperative Complications, Anesthesia
- Trial name
- NCT06209437
- Where
- Turkey (Türkiye)
- Volunteers
- 228 people
- Sponsor
- Ankara City Hospital Bilkent
Chronic Total Occlusion of Coronary Artery
Application of Coronary Artery Chronic Total Occlusion Scoring Systems
Studying the prediction ability of different CTO scoring systems on Asian CTO PCI population with their relation to technical success and developing a newer stepwise approach depending on these CTO scoring systems for choosing…
- Trial name
- CTO-PCI (NCT05883579)
- Testing
- percutaneous coronary intervention
- Where
- Taiwan
- Volunteers
- 650 people
- Sponsor
- Assiut University
Myocardial Ischaemia
Comparison of the Effect of Two Anaesthesia Methods in Preventing Perioperative Myocardial Infarcation in Patients With Cardiac Risk Undergoing Total Knee Arthroplasty
Comparison of the effect of two anaesthesia methods in preventing perioperative myocardial infarction in patients with cardiac risk undergoing total knee arthroplasty
- Trial name
- NCT05340946
- Testing
- general anaesthesia, spinal anaesthesia
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Chronic Total Occlusion of Coronary Artery
CT Coronary Angiography Prior to CTO PCI
A Chronic Total Occlusion or CTO of a coronary artery is a an artery that has been blocked for >/= 3 months. More than a decade ago, patients with such coronary artery blockage would have been sent for Coronary Artery Bypass…
- Trial name
- NCT05364827
- Testing
- CTCA
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Sandwell & West Birmingham Hospitals NHS Trust
Coronary Chronic Total Occlusion
Study to Evaluate the Safety and Efficacy of the CiTop™ ExPander™ Guidewire for Crossing Chronic Total Occlusions in Coronary Arteries
A multicenter multinational study to evaluate the safety and efficacy of the CiTop™ ExPander™ Guidewire for crossing chronic total occlusion in Coronary arteries.
- Trial name
- NCT00733070
- Testing
- CiTop™ ExPander™ Guidewire
- Where
- 3 sites in Germany, South Africa
- Volunteers
- 30 people
- Sponsor
- Ovalum
Coronary Artery Disease
The Effect of GRAVITY on Physiological Measurements During Invasive Coronary Angiography and Intervention
This is a single centre observational study on the impact of change in patient position and hence gravity, on physiological measurements in coronary arteries.
- Trial name
- GRAVITY (NCT03097172)
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- Mid and South Essex NHS Foundation Trust
Angina (Stable), Coronary Occlusion
Drug-Coated Balloon Only Strategy After Recanalization of Chronic Total Coronary Occlusions
Chronic total occlusions (CTO) of the coronary arteries are usually treated with drug-eluting stents (DES) after successful recanalization.
- Conditions
- Angina (Stable), Coronary Occlusion, Coronary Artery Disease, Chronic Total Occlusion
- Trial name
- NoTrace-CTO (NCT07817719)
- Testing
- Paclitaxel-coated balloon (AGENT Paclitaxel-Coated PTCA Balloon Catheter), Serial intravascular ultrasound and protocol-mandated nine-month angiographic reassessment
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- University of Sao Paulo General Hospital
Chronic Total Occlusion of Coronary Artery, Microvascular Coronary Artery Disease
Microvascular Coronary Resistance and Absolute Coronary FLOW in Patients With Percutaneous Intervention of a Chronic Total Occlusion
It is an observational study which objective is to analyze, through a series of invasive parameters, the state of the coronary microvasculature immediately after the successful percutaneous coronary intervention of a chronic…
- Conditions
- Chronic Total Occlusion of Coronary Artery, Microvascular Coronary Artery Disease, Coronary; Ischemic, Coronary Microvascular Dysfunction
- Trial name
- FLOW-CTO (NCT05197361)
- Testing
- Invasive coronary physiology
- Where
- 4 sites in Spain
- Volunteers
- 34 people
- Sponsor
- Parc de Salut Mar
Coronary Heart Disease, Chronic Total Occlusion of Coronary Artery
CTO Registry From Insight of IVUS in Fuwai Hospital
To evaluate the long-term outcome of chronic total occlusion (CTO) patients underwent contemporary percutaneous coronary intervention (PCI) techniques, we design this single-center, large-sample, prospective registry with…
- Conditions
- Coronary Heart Disease, Chronic Total Occlusion of Coronary Artery, Percutaneous Coronary Intervention, Intravascular Ultrasound
- Trial name
- FWCTO (NCT03461367)
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Artery Disease
GISSOC II: Sirolimus Eluting Stent Versus Bare Metal Stent in Chronic Total Coronary Occlusions
The objective of this study is to compare the Cypher Select-TM Sirolimus Eluting Stent (SES) with the SONIC-TM Bare Metal Stent (BMS) in the treatment of Chronic Total Occlusion lesions (CTO).
- Trial name
- NCT00220558
- Testing
- Coronary placement of bare metal stent vs. drug eluting stent
- Where
- 14 sites in Italy
- Volunteers
- 150 people
- Sponsor
- Società Italiana di Cardiologia Invasiva
Chronic Total Occlusion of Coronary Artery
OCT Explores Vascular Response and Healing Profile After Stenting in CTO
True-false-true occurred during wire penetration in coronary CTO procedure. Subintimal stenting influences vascular response. Intravenous ultrasound confirmed wire position in the procedure. Then stenting procedure was performed.
- Trial name
- NCT03939299
- Testing
- OCT
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Zhongshan Hospital
Congenital Heart Disease, Coarctation of Aorta
An Integrated Prenatal and Postnatal Treatment Model for the Treatment of Newborns With Critical Congenital Heart Disease
The purpose of this two-way cohort study was to explore whether an integrated prenatal and postnatal treatment model for neonates with critical congenital heart disease (CCHD) could be effective in avoiding preoperative…
- Conditions
- Congenital Heart Disease, Coarctation of Aorta, Aortic Stenosis, Pulmonary Atresia
- Trial name
- NCT06768008
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Beijing Anzhen Hospital