Clinical trials: Total Thyroidectomy, open to volunteers
Total Thyroidectomy
Impact of Manual Therapy on Laryngeal Function Following Total Thyroidectomy
In this clinical trial, the investigators are seeking to learn if a course of voice therapy, including neck massage, stretches and pain science education in addition to voice exercise and scar massage will effectively treatment…
- Trial name
- Man Total Thy (NCT06383091)
- Testing
- Anterior Neck Manual Therapy, Pain Neuroscience Education, Neck Stretches
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Total Thyroidectomy, Hyperthyroidism
Evaluation of Levothyroxine Replacement Therapy After Total Thyroidectomy Using a Smart Wristband
The goal of this observational study is to determine whether nighttime heart rate and heart rhythm data collected by a smart wristband can identify under- or over-replacement with levothyroxine before the routine 1-month thyroid…
- Conditions
- Total Thyroidectomy, Hyperthyroidism, Hypothyroidism
- Trial name
- SMART-THY (NCT07733375)
- Testing
- Xiomi Smart Band 10
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Yeditepe University Hospital
Thyroidectomy, Cervical Plexus Block
The Effect of Bilateral Intermediate Cervical Plexus Block on the Surgical Stress Response Following Total Thyroidectomy
Total thyroidectomy triggers a systemic surgical stress response involving neuroendocrine and inflammatory pathways. Ultrasound-guided bilateral intermediate cervical plexus block (BICPB) is commonly utilized for postoperative…
- Conditions
- Thyroidectomy, Cervical Plexus Block, Surgical Stress Response
- Trial name
- NCT07740460
- Testing
- Ultrasound-Guided Bilateral Intermediate Cervical Plexus Block Using 0,25% Levobupivacaine
- Volunteers
- 48 people
- Sponsor
- University Hospital Dubrava
Total Thyroidectomy
Impact of Travel Neck Pillow Use on Neck Comfort and Mobility After Thyroidectomy
This study aims to evaluate the effectiveness of U-shaped travel neck pillow use in improving cervical comfort, reducing neck pain and stiffness, and enhancing cervical range of motion in adults undergoing total thyroidectomy…
- Trial name
- TiNeCoM (NCT06909513)
- Testing
- U-shaped Travel Neck Pillow
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- TC Erciyes University
Throid Surgery, Airway Complication of Anaesthesia
Comparison of the Effects of Total Intravenous Anaesthesia With Target-Controlled Infusion (TCI) and Inhalation Anaesthesia on Airway Complications During Extubation and in the Early Postoperative Period in Thyroidectomy Surgery
Thyroid surgery is one of the most complex operations in the head and neck region due to its close relationship with anatomical structures and the high risk of recurrent laryngeal nerve injury.
- Conditions
- Throid Surgery, Airway Complication of Anaesthesia, Coughing Responses at Tracheal Extubation, Laryngospasm on Emergence
- Trial name
- NCT07325669
- Testing
- tıva
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- dilara gocmen
Surgical Stress Response, Total Thyroidectomy
The Association Between Bilateral Intermediate Cervical Plexus Block and Salivary Biomarkers of Surgical Stress Response Following Total Thyroidectomy
The aim of this study is to evaluate how an ultrasound-guided bilateral intermediate cervical plexus block affects the surgical stress response in individuals undergoing total thyroidectomy.
- Conditions
- Surgical Stress Response, Total Thyroidectomy, Saliva Collection, Cervical Plexus Block
- Trial name
- NCT07721818
- Testing
- Ultrasound guided bilateral intermediate cervical plexus block
- Volunteers
- 48 people
- Sponsor
- University Hospital Dubrava
Hypocalcemia, Hypoparathyroidism
NIRAF-Guided Parathyroid Identification During Thyroidectomy
This study evaluates whether a wearable near-infrared autofluorescence (NIRAF) imaging system can help surgeons identify and preserve parathyroid glands during thyroid surgery.
- Conditions
- Hypocalcemia, Hypoparathyroidism, Thyroid Diseases, Goiter, Nodular
- Trial name
- NCT07617584
- Testing
- Wearable Near-Infrared Autofluorescence Imaging System
- Where
- North Macedonia
- Volunteers
- 280 people
- Sponsor
- Ss. Cyril and Methodius University of Skopje
Thyroid Cancer, Thyroid and Parathyroid Surgery
The Association Between Bilateral Intermediate Cervical Plexus Block During Total Thyroidectomy and Surgical Stress Response
The aim of this study is to determine the impact of ultrasound-guided bilateral intermediate cervical plexus block on the surgical stress response in patients undergoing total thyroidectomy, as measured by the concentration of…
- Conditions
- Thyroid Cancer, Thyroid and Parathyroid Surgery, Hyperthyreosis and Goiter, Surgical Stress Response
- Trial name
- NCT07600580
- Testing
- bilateral ultrasound guided intermediate cervical plexus block with 0,25% levobupivacaine
- Where
- Croatia
- Volunteers
- 48 people
- Sponsor
- University Hospital Dubrava
Thyroid Diseases
Contribution of ICG Angiography in the Detection of Parathyroids and the Prevention of Hypoparathyroidism Post Total Thyroidectomy
Hypoparathyroidism is the most common complication after a total thyroidectomy surgery. It becomes permanent after 6 months. Untreated permanent hypoparathyroidism is a source of numerous complications in general and therefore…
- Trial name
- HYPOCAAVI (NCT04785443)
- Testing
- ICG, Control group
- Where
- France
- Volunteers
- 242 people
- Sponsor
- University Hospital, Brest
Hashimoto Thyroiditis, Goiter
Role of Total Thyroidectomy in Relieving Local Symptoms in Hashimoto's Thyroiditis
This study aims to evaluate the role and effectiveness of total thyroidectomy in relieving compressive and local symptoms (such as dysphagia, dyspnea, and anterior neck pain/discomfort) in patients with Hashimoto's thyroiditis…
- Trial name
- NCT07852026
- Testing
- Total Thyroidectomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Differentiated Thyroid Cancer
Hemithyroidectomy or Total-Thyroidectomy in 'Low-risk' Thyroid Cancers
This is a multi-centre, randomised, non-inferiority, phase III study in patients with low risk differentiated thyroid cancer. Patients will be identified via oncology multidisciplinary team meetings.
- Trial name
- HoT (NCT05604963)
- Testing
- Total Thyroidectomy, Hemithyroidectomy
- Where
- 33 sites in United Kingdom
- Volunteers
- 456 people
- Sponsor
- University College, London
Hypoparathyroidism Post-surgical, Quality of Life
Effects of Total Thyroid Removal on Parathyroid Function and Quality of Life
Postoperative hypoparathyroidism (hypoPT) is the most frequent complication after total thyroidectomy (TT). It is caused by impaired parathyroid function, leading to low calcium levels, patient discomfort, reduced quality of life…
- Trial name
- NCT07381998
- Testing
- high-dose calcium (400 mg x 4), vitamin D (19 mikg x 4), and active vitamin D supplementation (2 mikg x 2), Ommit routine blood test post operative day 1
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Aarhus University Hospital
Postoperative Symptomatic Hypocalcemia Following Total Thyroidectomy
COMPARISON OF THE EFFICACY BETWEEN PREOPERATIVE CALCIUM & VITAMIN D3 VERSUS CALCIUM SUPPLEMENTATION ALONE TO PREVENT POST OPERATIVE SYMPTOMATIC HYPOCALCEMIA AFTER TOTAL THYROIDECTOMY IN EUTHYROID PATIENTS
Total thyroidectomy is a commonly performed surgery for thyroid diseases such as multinodular goiter. One of the most frequent complications after this procedure is hypocalcemia (low blood calcium levels), which may cause…
- Trial name
- NCT07597096
- Testing
- Calcium carbonate plus vitamin D3 (cholecalciferol)
- Where
- Pakistan
- Volunteers
- 124 people
- Sponsor
- King Edward Medical University
Thyroidectomy, Oxidative Stress
Opioid-Free Versus Opioid-Based Anesthesia in Thyroid Surgery
This study will compare opioid-free anesthesia and opioid-based anesthesia in adult euthyroid patients undergoing elective thyroidectomy.
- Conditions
- Thyroidectomy, Oxidative Stress, Anesthesia
- Trial name
- OFA-OBA (NCT07864155)
- Testing
- Fentanyl (IV), Dexmedetomidine and lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Malatya Egitim Ve Arastirma Hastanesi
Thymectomy, Thyroid Cancer
Comparing the Therapeutic Efficacy of Extended Isthmusectomy Versus Total Thyroidectomy for Isthmus Tumors of the Thyroid
Prospective randomized open phase III non-inferiority trial in cT1bN0N1aM0 isthmus tumors of the thyroid comparing: extended Isthmusectomy (Isthmusectomy + Central Neck Dissection)(experimental group) versus total thyroidectomy +…
- Trial name
- NCT07274605
- Testing
- Total thyroidectomy, Extended isthmusectomy
- Where
- China
- Volunteers
- 520 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Postoperative Pain
Postoperative Analgesia and Recovery Quality in Total Thyroidectomy
This prospective observational study evaluates the association between postoperative analgesic approaches and recovery outcomes in patients undergoing elective total thyroidectomy.
- Trial name
- NCT07547124
- Testing
- Cervical Plexus Block
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istinye University
Hypocalcemia
Total Post-thyroidectomy Hypocalcemia After Preoperative Cholecalciferol Supplementation
This prospective study evalue the inflence of pre operative vit D3 administration on post operative hypocalcemia in patients undergoing Total thyroidectomy
- Trial name
- CAVITHY (NCT04775381)
- Testing
- Vitamin D
- Where
- 6 sites in France
- Volunteers
- 200 people
- Sponsor
- Hôpital NOVO
Thyroid Surgery, Inadvertent Parathyroidectomy
Use of the PTEye Device to Reduce Inadvertent Parathyroidectomy During Thyroid Surgery
Inadvertent Parathyroidectomy (IP) during thyroid surgery may lead to transient or permanent hypoparathyroidism and hypocalcemia, which represents significant morbidity.
- Conditions
- Thyroid Surgery, Inadvertent Parathyroidectomy, Enlarged Thyroid
- Trial name
- NCT06927245
- Testing
- PTeye Device
- Volunteers
- 25 people
- Sponsor
- ProMedica Health System
Hypocalcemia, Parathyroid
Comparing PTeye-assisted Versus Conventional Total Thyroidectomy
This is a prospective, single-blinded, randomized controlled trial to evaluate whether PTeye™ can reduce post-operative hypoparathyroidism (PH).
- Conditions
- Hypocalcemia, Parathyroid, Hypoparathyroidism Post-surgical, Total Thyroidectomy
- Trial name
- NCT07416149
- Testing
- PTeye™ parathyroid detection system
- Where
- Hong Kong
- Volunteers
- 210 people
- Sponsor
- The University of Hong Kong
Thyroid Nodule, Thyroid Dysfunction
Postoperative Hypocalcemia After Thyroidectomy
This retrospective cohort study investigates predictors of postoperative hypocalcemia following thyroidectomy procedures at Minia University Hospital over a 10-year period (2014-2024).
- Conditions
- Thyroid Nodule, Thyroid Dysfunction, Hypocalcemia, Thyroid Cancer
- Trial name
- NCT07428057
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Minia University