Clinical trials: Total Vaginal Hysterectomy
Prolapse, Vaginal, Vaginal Vault Prolapse
Post-Hysterectomy Vaginal Length: Horizontal vs. Vertical Closure
This prospective clinical study aims to evaluate the impact of vaginal cuff closure orientation-horizontal versus vertical-on postoperative total vaginal length in patients undergoing vaginal hysterectomy combined with lateral…
- Trial name
- vagina (NCT07067645)
- Testing
- Horizontal Vaginal Cuff Closure Technique, Vertical Vaginal Cuff Closure Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Hysterectomy, Vascularization
Study of the Vascularization of the Vaginal Slice After Total Laparoscopic Hysterectomy, Using Indocyanine Green Injection.
Hysterectomy is one of the most common surgical procedures in gynecology, especially by laparoscopy. Post-operative complications of hysterectomy are numerous and their causes are poorly understood.
- Conditions
- Hysterectomy, Vascularization, Complication of Surgical Procedure
- Trial name
- HYSTINDO (NCT06608082)
- Testing
- indocyanine green injected intravenously
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Clermont-Ferrand
Surgical Wound Dehiscence
Vaginal Cuff Dehiscence at Total Laparoscopic Hysterectomy
The aim of this study is to assess a major complication of total laparoscopic hysterectomy, vaginal dehiscence, with two different colpotomy techniques.
- Trial name
- NCT02879487
- Testing
- Monopolar needle electrode
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ankara University
Hysterectomy, Benign Uterine Diseases
Effect of Posterior Colpotomy First Technique on the Vaginal Length During Total Abdominal Hysterectomy
the same surgeon performed all of the procedures using the same method. A lower midline or Pfannestiel incision is the first step in the complete abdominal hysterectomy procedure. They clamp, cut, and ligate the top pedicles.
- Trial name
- NCT07308197
- Testing
- Abdominal hysterectomy
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Surgical Wound Dehiscence
Vaginal Cuff Dehiscence Following Total Laparoscopic Hysterectomy: Laparoscopic vs. Transvaginal Cuff Closure
Post-hysterectomy vaginal cuff dehiscence is a rare but threatening complication. The investigators will compare transvaginal versus laparoscopic closure of the vaginal vault at the end of a total laparoscopic hysterectomy, in…
- Trial name
- NCT02453165
- Testing
- TRANSVAGINAL SUTURE, LAPAROSCOPIC SUTURE
- Where
- Italy
- Volunteers
- 1,408 people
- Sponsor
- Università degli Studi dell'Insubria
Hysterectomy, Sacrocolpopexy
Permanent Versus Delayed-Absorbable Monofilament Suture
This is an extension study of a prospective, multicenter, randomized, single-blind trial whose purpose is to compare mesh-related complications and effectiveness of pelvic organ prolapse (POP) repair in women undergoing…
- Trial name
- E-PACT (NCT04506177)
- Where
- 5 sites in United States
- Volunteers
- 200 people
- Sponsor
- Wake Forest University Health Sciences
Vaginal Cuff Complications
BARBED vs. STANDARD Suture for Colporrhaphy at the End of Laparoscopic Hysterectomy
Hysterectomy is one of the most common surgical procedures performed worldwide, with more than 400,000 hysterectomies performed annually in the United States.
- Trial name
- BARD (NCT05833204)
- Testing
- Laparoscopic colporrhaphy with 0-caliber barbed absorbable suture, Laparoscopic colporrhaphy with standard 0-caliber absorbable suture
- Where
- Italy
- Volunteers
- 1,614 people
- Sponsor
- Universita di Verona
Hysterectomy
Barbed Versus Conventional Sutures for Vaginal Cuff Closure During Total Laparoscopic Hysterectomy
The aim of this study is to estimate whether the use of the barbed suture facilitates laparoscopic suturing of the vaginal cuff during total laparoscopic hysterectomy.
- Trial name
- NCT02998658
- Testing
- Vaginal cuff closure using barbed sutures, Vaginal cuff closure using conventional sutures
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Cairo University
Total Laparoscopic Hysterectomy
Laparoscopic Versus Transvaginal Closure of the Vaginal Vault After Total Laparoscopic Hysterectomy
The goal of this clinical trial is to compare the laparoscopic and transvaginal closure techniques of the vaginal vault in patients who perform TLH, regarding the risk of vaginal vault hematoma and other complications as vaginal…
- Trial name
- NCT06867614
- Testing
- Total laparoscopic hysterectomy
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Ain Shams University
Pelvic Organ Prolapse
Permanent Versus Absorbable Colpopexy Trial
Primary Aim: The primary aim of this randomized controlled trial (RCT) is to compare vaginal mesh and suture exposure rates in women undergoing robotic total hysterectomy and sacrocolpopexy with a light-weight polypropylene mesh…
- Trial name
- PACT (NCT02277925)
- Testing
- Polytetrafluoroethylene, Polydioxanone
- Where
- 5 sites in United States
- Volunteers
- 204 people
- Sponsor
- University of North Carolina, Chapel Hill
Hysterectomy, Benign Uterine Diseases
Comparison of TLH and LAVH With Over Than 500g
Since the introduction of total laparoscopic hysterectomy in 1989, laparoscopic gynecologic surgery has undergone many advances.
- Trial name
- NCT03146299
- Testing
- TLH vs LAVH
- Volunteers
- 34 people
- Sponsor
- Hanyang University Seoul Hospital
Pelvic Organ Prolapse
Laparoscopic Hysterectomy With Vaginal Vault Suspension to the Uterosacral Ligaments for Stage II-III Pelvic Organ Prolapse.
The International Continence Society defines post-hysterectomy vault prolapse (PHVP) as descent of the vaginal cuff scar below a point that is 2 cm less than the total vaginal length above the plane of the hymen.
- Trial name
- LULS-1 (NCT03553511)
- Testing
- Vaginal vault suspension to the uterosacral ligaments, McCall culdoplasty
- Volunteers
- 60 people
- Sponsor
- Università degli Studi dell'Insubria
Laparoscopic Hysterectomy, Vaginal Infection
Vaginal Stump Infection After Laparoscopic Hysterectomy
Comparing two surgical techniques in relation to vaginal stump infection, analysis of patient-based and therapy-based risk factors.
- Trial name
- CoToIn (NCT04725981)
- Testing
- Total laparoscopic hysterectomy
- Where
- Switzerland
- Volunteers
- 141 people
- Sponsor
- Spital Limmattal Schlieren
Abnormal Uterine Bleeding, Uterine Bleeding
Outcomes on Abdominal Versus Vaginal Morcellation At Time of Hysterectomy
The purpose of the study is to investigate differences in perioperative and postoperative outcomes between the abdominal (AM) versus vaginal (VM) routes of contained morcellation in participants undergoing laparoscopic total…
- Conditions
- Abnormal Uterine Bleeding, Uterine Bleeding, Fibroid Uterus, Surgery
- Trial name
- NCT04434066
- Testing
- Total Laparoscopic Hysterectomy
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Vaginal Cuff Dehiscence, Vaginal Hematoma
Laparoscopic Versus Transvaginal Cuff Closure
It is still debatable whether that the transvaginal approach to vault closure or laparoscopic suturing are associated with lower risks of vaginal cuff complications .
- Conditions
- Vaginal Cuff Dehiscence, Vaginal Hematoma, Vaginal Infection
- Trial name
- NCT03898726
- Testing
- laparoscopical l cuff closure
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- El-Galaa Military Medical Complex
Benign Uterine Disease
LESS-TLH Versus LESS-LAVH
During the last 2 decades, several studies have tried to define the best surgical approach to hysterectomy for benign uterine diseases1.
- Trial name
- NCT01861067
- Testing
- LESS-TLH, LESS-LAVH
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- CHA University
Same Day Discharge, Pelvic Organ Prolapse
Same Day Discharge Following Pelvic Reconstructive Surgery
This is a prospective cross-sectional study in which patients undergoing major pelvic reconstructive surgery with total vaginal hysterectomy will be recruited and enrolled.
- Conditions
- Same Day Discharge, Pelvic Organ Prolapse, Total Vaginal Hysterectomy
- Trial name
- NCT04804826
- Testing
- Pelvic Reconstructive Surgery
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- TriHealth Inc.
Laparoscopic Hysterectomy for Benign Conditions
Comparing Two Devices of Uterine Manipulation and Vaginal Fornix Delineation at Total Laparoscopic Hysterectomy
We hypothesize, that the use of the Hohl manipulator® at total laparoscopic hysterectomy reduces operative time (from skin incision to detachment of the uterus) and lateral termal damage of the vaginal wall during colpotomy due…
- Trial name
- NCT02197728
- Testing
- Use of the Colpo-Probe™ Vaginal Fornix Delineator or Hohl manipulator® during total laparoscopic hysterectomy
- Where
- Canada
- Volunteers
- 91 people
- Sponsor
- Unity Health Toronto
Infection, Bleeding
Effects of Microcrystalline Titanium Dioxide With Covalently Linked Monovalent Silver Ions on Complications After Total Hysterectomy
Total hysterectomy is one of the most performed surgical procedures in the world and it is associated with post-operative complications.
- Conditions
- Infection, Bleeding, Complication, Postoperative
- Trial name
- ISTIAB-1 (NCT03789799)
- Testing
- TIAB: microcrystalline titanium dioxide with covalently linked monovalent silver ions
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Università degli Studi dell'Insubria
Pain, Postoperative
Long-acting Local Vaginal Cuff Anesthesia Following Hysterectomy
The purpose of this study is to compare recovery unit and post operation day (POD) 1 pain score in women following elective robotic assisted TLH (RA-TLH) for benign indication with and without local vaginal cuff injection of…
- Trial name
- LAVA (NCT07842159)
- Testing
- Combined Bupivacaine and Exparel, Normal Saline (NS)
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- The University of Texas Health Science Center, Houston