Clinical trials: Tourniquet
Tourniquet Pain, Ischemia-reperfusion
The Effect of Prolonged ischemıa and anesthetıc Agents on Oxidative Stress
The goal of this observational study is to learn about the relationship between postoperative pain and tourniquet-induced oxidative damage in adults undergoing orthopedic knee arthroscopy surgery.The goal of this observational…
- Conditions
- Tourniquet Pain, Ischemia-reperfusion, Postoperative Pain, Anesthesia
- Trial name
- NCT06942650
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Duzce University
Osteo Arthritis Knee, Arthroplasty, Replacement, Knee
Sharp Dissection Versus Monopolar Electrocautery in Primary Total Knee Arthroplasty Performed Under Tourniquet
This study compares the use of sharp dissection with diathermy for the approach to a total knee replacement. Half of the patients will be randomly assigned each intervention.
- Trial name
- NCT03559478
- Testing
- Sharp dissection with scalpel plus electrocautery to vessels, Electrocautery for all dissection
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Royal Infirmary of Edinburgh
Hemorrhage
Tourniquets Type Combat Application Tourniquet: Proximal or Distal Location, Simple or Staggered on Upper and Lower Limb
A tourniquet is used to stop abundant bleeding when simple compression is not effective. The investigators will study the vascular suffering of the tourniquets according to their location on the limb: limb (arm / thigh) or distal…
- Trial name
- GARROTS (NCT03218176)
- Testing
- Proximal single upper limb, Proximal staggered upper limb, Distal single upper limb
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Carpal Tunnel Syndrome
Novel Decision Aid for Carpal Tunnel Patients
A questionnaire will be given to patients who are considering undergoing hand surgery as a treatment for Carpal Tunnel Syndrome to help participants decide between two surgical options- Wide-Awake-Local-Anesthesia-no-Tourniquet…
- Trial name
- NCT04693273
- Testing
- Decision Aid for Surgical Modality Choice
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Henry Ford Health System
Vascular Diseases
Minimal Inflation Tourniquet Pressure Using Induced Hypotension
Limb occlusion pressure (LOP) and arterial occlusion pressure (AOP) are the terms that mean the lowest tourniquet pressure required to stop the arterial blood flow into the limb distal to the cuff.
- Trial name
- NCT04055779
- Testing
- estimation method for arterial occlusion pressure, the limb occlusion pressure
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Arthropathy of Knee Joint
Total Knee Arthroplasty - Accelerated Recovery Without Tourniquet
Introduction: Approximately 7000 total knee replacements (TKAs) are done every year. More than 90% of these knee replacements are performed with the use of bone cement.
- Trial name
- NCT01309035
- Testing
- Total Knee Arthroplasty
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Arrhythmia, Cardiac, Tourniquet Complications
Effect of Tourniquet Use on ICEB and ICEBc in Upper Extremity Surgeries
In our study, we will examine whether the pressure bandage (tourniquet) used to reduce bleeding during surgery in patients with arm fractures has an effect on heart rhythm.
- Trial name
- NCT06936150
- Testing
- Electrocardiography
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Osteoarthritis
Efficacy of Lower Tourniquet Pressure During Total Knee Arthroplasty
This study aims to determine whether the lower tourniquet pressure, which is set by adding 120mmHg (millimeter of mercury) on the systolic blood pressure just before tourniquet inflation, are efficient and safe during total knee…
- Trial name
- NCT01993758
- Testing
- Low tourniquet pressure, Conventional tourniquet pressure
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- Seoul National University Hospital
Trauma (Including Fractures), Dialysis Catheter
WALANT Versus Local Anesthesia in Central Venous Catheter Insertion
The goal of this clinical trial is to find out whether WALANT is an alternative local anesthesia method that can increase patient comfort and reduce pain during CVC procedure, which is one of the invasive procedures to be…
- Conditions
- Trauma (Including Fractures), Dialysis Catheter, Malnutrition Severe
- Trial name
- WALANT (NCT07299383)
- Testing
- local anesthesia with walant solution, Local anesthesia with lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Ataturk University
Hypotension, Sepsis
Lactic Acid Levels In Hypotensive Patients Without(Standard) and With Tourniquet
This study seeks to determine whether the Lactic Acid blood level in a critically ill patient must be drawn with a non-tourniquet venipuncture.
- Trial name
- NCT00750516
- Where
- United States
- Sponsor
- State University of New York - Upstate Medical University
Ischemia Reperfusion Injury
The Effect of Pregabalin Given Preoperatively on the Tourniquet Induced Ischemia-reperfusion
The application of tourniquet is indispensable for a bloodless surgical area in total knee arthroplasty surgery. The release of tourniquet produces reactive oxygen species which can cause injury and then ischemia-reperfusion…
- Trial name
- NCT03482544
- Testing
- Pragabalin
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Baskent University
Bier Block, Dexmedetomidine
A Sequential Allocation Study to Determine the ED50 of Dexmetedomidine as an Adjuvant to Lidocaine Intravenous Regional Anesthesia
Intravenous Regional Anesthesia (IVRA) is an easy and reliable anesthetic technique for hand and forearm surgery. Its use is however limited by the presence of tourniquet pain during the surgery and the absence of postoperative…
- Conditions
- Bier Block, Dexmedetomidine, Tourniquet Pain, Carpal Tunnel
- Trial name
- NCT05342870
- Testing
- Dexmedetomidine
- Volunteers
- 23 people
- Sponsor
- American University of Beirut Medical Center
Placenta Accreta
The Efficacy of a Temporary Sub-Placental Uterine Tourniquet in Minimizing Intraoperative Blood Loss in Management of Placenta Accreta Spectrum Disorder by a Retrograde Cesarean Hysterectomy (Bladder Last)
This trial will study the role of a temporary tourniquet around the uterus to reduce blood loss in management of patients with abnormally implanted placenta who will undergo removal of the uterus.
- Trial name
- NCT05936645
- Testing
- A temporary sub-placental Uterine Tourniquet in management of Placenta Accreta Spectrum disorder by a retrograde cesarean hysterectomy (Bladder Last), Retrograde cesarean hysterectomy (Bladder Last) for management of Placenta Accreta Spectrum disorder
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Upper Limb Wound, Lower Limb Wound
Wide-awake Local Anesthesia and no Tourniquet (WALANT) in Plastic Surgery
Wide-awake local anesthesia no tourniquet (WALANT) was proposed and performed in hand operations. Aim of this study is to present the use of WALANT in operations performed on the upper and lower limbs, evaluate its efficacy in…
- Conditions
- Upper Limb Wound, Lower Limb Wound, Anesthesia, Local
- Trial name
- NCT04992351
- Testing
- WALANT
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- University Hospital, Ioannina
Major Depressive Disorder, Bipolar Disorder
Venous Tourniquet vs. Arterial Tourniquet for Seizure Monitoring in ECT
This prospective, open-label clinical trial aims to compare a novel "Venous Tourniquet with Regional Low-Dose Sugammadex" method against the gold standard "Arterial Tourniquet" (Isolated Forearm Technique - IFT) for monitoring…
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Schizophrenia
- Trial name
- NCT07534475
- Testing
- Device: Arterial Tourniquet, Device: Venous Tourniquet, Sugammadex
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Medipol University
Hematoma, Arthroplasty Complications
The Effect of Releasing the Tourniquet in Total Knee Replacement Before Closure on the Blood Loss , Joint Effusion , Hematoma Formation and Wound Complication
The study , observe the effect of releasing the Tourniquet in total knee replacement surgery before closure in comparison with releasing it after wound closure The effect was assessed by Hb drop post operative and Hematoma…
- Trial name
- NCT04810000
- Testing
- tourniquet
- Where
- Jordan
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Yazan Saleh Rajab Hammad
Laparoscopic Liver Resection, Vascular Occlusion
Bulldog vs. Cotton Tourniquet in Laparoscopic Hepatectomy for Patients
LLR was applied for tumors located at the lower edge and lateral segments of the liver that could be resected more easily than posterosuperior segments.
- Conditions
- Laparoscopic Liver Resection, Vascular Occlusion, Tourniquet
- Trial name
- NCT04277065
- Testing
- BULLDOG ,A Useful Vascular Occlusion Tourniquet In Laparoscopic Liver Resection, cotton tourniquet
- Where
- China
- Volunteers
- 88 people
- Sponsor
- hui hou
Arthroplasty, Replacement, Knee, Blood Loss, Surgical
Early Outcome of Simultaneous Bilateral Total Knee Replacement With and Without Tourniquet
This randomized controlled trial compared early outcomes after replacement of both knees during the same operation, with and without tourniquet use.
- Conditions
- Arthroplasty, Replacement, Knee, Blood Loss, Surgical, Pain, Postoperative
- Trial name
- NCT07905495
- Testing
- Simultaneous Bilateral Total Knee Replacement with Tourniquet, Simultaneous Bilateral Total Knee Replacement without Tourniquet
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- Shifa International Hospital
Osteoarthritis
Tourniquet vs. no Tourniquet During Total Knee Arthroplasty
The purpose of this study is to correlate functional outcomes and perioperative complications with tourniquet use during total knee arthroplasty.
- Trial name
- NCT02907047
- Testing
- tourniquet inflated, tourniquet not inflated
- Where
- United States
- Sponsor
- Rothman Institute Orthopaedics
Hypotension, Tachycardia
Passive Leg Raising Attenuates and Delays Tourniquet Deflation-induced Hypotension and Tachycardia
Background: The pneumatic tourniquet is frequently used in total knee arthroplasty. Tourniquet deflation may result in hypotension and tachycardia caused by the rapid shift of blood volume back to the ischemic limb and a decrease…
- Trial name
- NCT01592669
- Testing
- passive leg raising
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- Tri-Service General Hospital (TSGH)