Clinical trials: Tourniquet Pain
Total Blood Loss
Evaluation of Blood Loss and Pain in TKA With and Without Pneumatic Tourniquet, A Randomized Controlled Trial
The aim of our study is to determine whether the use of a tourniquet during TKA would affect total measured blood loss , operation time, postoperative complications; hemoglobin concentration; limb swelling and postoperative pain.
- Trial name
- NCT05144425
- Testing
- total knee arthroplasty with and without using pneumatic tourniquet
- Volunteers
- 100 people
- Sponsor
- Assiut University
Ankle Fracture
Ankle Fracture Tourniquet Utilization
Lower extremity tourniquet utilization remains a controversial practice during the operative fixation of rotational ankle fractures and is often left to surgeon discretion.
- Trial name
- NCT06863688
- Testing
- Tourniquet, No Tourniquet
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Alex Demers
Hand Injuries/Disease Requiring Surgery to the Hand
A Study Investigating Ways to Make Local Anaesthetic Hand Surgery Less Painful - Reducing Tourniquet Associated Pain
Hand surgery requires a reduced blood flow to the hand during the operation, which is achieved using a tourniquet (tightly inflated circumferential cuff) around the upper arm. However this tourniquet is painful.
- Trial name
- ReTAP (NCT01611064)
- Testing
- Oxygen, Medical air
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Carpal Tunnel Syndrome
Pain in Carpal Tunnel Release Wide-awake Local Anesthesia With no Tourniquet vs Local Anesthesia With Tourniquet
The aim of this study is to compare pain, satisfaction, and experience between patients who underwent Carpal Tunnel Release with wide-awake local anesthesia no tourniquet technique and local anesthesia with a tourniquet.
- Trial name
- NCT05747846
- Testing
- Carpal tunnel release, WALANT technique, Carpal tunnel release using a tourniquet
- Where
- Argentina
- Volunteers
- 82 people
- Sponsor
- Hospital Italiano de Buenos Aires
Injection Site Irritation, Pain
Lidocaine, Esmolol, or Placebo to Relieve IV Propofol Pain
The primary hypothesis is that esmolol and lidocaine, when given without the use of a tourniquet, provide relief of propofol injection pain that is superior to placebo when assessed using the propofol pain scoring tool
- Trial name
- NCT04356352
- Testing
- Lidocaine, Esmolol
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Wake Forest University Health Sciences
Orthopedic/Podiatry Procedures
Effects of Dexmedetomidine on Tourniquet Pain Associated With Lower Extremity Surgeries Under General Anesthesia
This study is being done to determine if the drug known as dexmedetomidine improves the way we care for patients when their surgery involves the use of a tourniquet on the leg.
- Trial name
- NCT00932386
- Testing
- Dexmedetomidine Hcl infusion, normal saline
- Where
- United States
- Sponsor
- Rutgers, The State University of New Jersey
Pain
Preventing Propofol-associated Injection Pain
Injection of propofol is associated with discomfort in subsets of patients. Local anesthetics have been shown to attenuate this response in some patients.
- Trial name
- NCT00864682
- Testing
- Saline, Lidocaine / propofol admixture, lidocaine pretreatment
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Benaroya Research Institute
Venous Puncture
Effect of Tourniquet Abstention on Pain Reduction in Venous Sampling in the Elderly People
This prospective study evaluates the effect of abstaining from tourniquets on pain reduction during the venous puncture of the elderly people.
- Trial name
- NO-GARROT (NCT05226364)
- Testing
- Rubber tourniquet, Fabric tourniquet, Without tourniquet
- Where
- 5 sites in France
- Volunteers
- 240 people
- Sponsor
- Hôpital NOVO
Tourniquets, Knee Arthroplasty, Total
Tourniquet Pressure in Primary Total Knee Arthroplasty
This proposed novel randomized control trial (RCT) seeks to address this gap in TKA protocol by gaining a better understanding of the relationship between tourniquet pressure and time, and intraoperative performance and…
- Conditions
- Tourniquets, Knee Arthroplasty, Total, Knee Replacement, Total
- Trial name
- NCT02830087
- Testing
- Tourniquet Cuff Pressure
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Tourniquet-induced Pain, Tourniquet-induced Hypertension
Efficacy of Gabapentin in Prevention of Tourniquet Pain and Hypertension
The purpose of the study is to find out if taking a dose of gabapentin 600 mg by mouth (po) before surgery will help prevent the development of tourniquet pain and hypertension while the tourniquet is inflated during orif of…
- Trial name
- NCT01441531
- Testing
- gabapentin 600 mg po
- Where
- United States
- Sponsor
- Baylor College of Medicine
Safety Issues, Post Operative Pain
Safety and Efficacy of Wide Awake Local Anesthesia no Tourniquet Technique (WALANT) in Ankle Removal of Implant Surgery
Safety and efficacy of wide awake local anesthesia no torniquet technique (WALANT) in ankle surgery. Studying risks and benefits from WALANT compared to general anesthesia .
- Conditions
- Safety Issues, Post Operative Pain, Local Anesthetic Complication
- Trial name
- NCT05864664
- Testing
- Wide awake local anaesthesia no tourniquet technique
- Where
- Kuwait
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ali Lari
Tourniquet-induced Pain, Procedural Pain
Comparison of Ketorolac and Dexmedetomidine as An Adjunct to Lignocaine in Prevention of Tourniquet Induced Pain During Intravenous Regional Anesthesia
This study compared ketorolac and dexmedetomidine when added to lignocaine to prevent pain caused by a tourniquet during intravenous regional anesthesia.
- Trial name
- NCT07878962
- Testing
- Dexmedetomidine, ketorolac, Lidocaine
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Mayo Hospital Lahore
Carpal Tunnel Syndrome
aDjunct bicarbonatE in Local anaesthesIa for CarpAl Tunnel rElease (DELICATE)
Introduction Carpal tunnel syndrome (CTS) is the most common peripheral nerve entrapment syndrome in Finland and worldwide. Nowadays carpal tunnel release (CTR) surgery is often done in local anaesthesia.
- Trial name
- DELICATE (NCT05328180)
- Testing
- Sodium bicarbonate, Control arm
- Where
- Finland
- Volunteers
- 116 people
- Sponsor
- Kuopio University Hospital
Forearm Surgery, US-Guided Supraclavicular Block
Analgesic Effect of Supraclavicular Block and Interscalene Analgesia Versus an Intercostobrachial Nerve Block Versus PCA in Forearm Surgery
The etiology of tourniquet pain is complex, and the study team hypothesizes that blocking with Interscalene brachial plexus block (ISBPB) is more efficient in decreasing the incidence of tourniquet pain in comparison with other…
- Conditions
- Forearm Surgery, US-Guided Supraclavicular Block, Interscalene Analgesia, Tourniquet Pain
- Trial name
- NCT05602636
- Testing
- bupivacaine, midazolam
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Osteoarthritis, Knee
Efficacy Testing of Different Tourniquet Pressure Used for Postoperative Pain Reduction in Total Knee Arthroplasty
Tourniquet use during total knee replacement (TKR) improves visibility, significantly decreases intra-operative blood loss and reduce operative time.
- Trial name
- NCT03931837
- Testing
- Tourniquet: Systolic blood pressure + 75 mmHg, Tourniquet: Systolic blood pressure + 100 mmHg, Tourniquet: Systolic blood pressure + 150 mmHg
- Where
- Thailand
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Thammasat University
Tourniquet Pain, Ischemia-reperfusion
The Effect of Prolonged ischemıa and anesthetıc Agents on Oxidative Stress
The goal of this observational study is to learn about the relationship between postoperative pain and tourniquet-induced oxidative damage in adults undergoing orthopedic knee arthroscopy surgery.The goal of this observational…
- Conditions
- Tourniquet Pain, Ischemia-reperfusion, Postoperative Pain, Anesthesia
- Trial name
- NCT06942650
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Duzce University
Total Knee Arthroplasty
Total Knee Arthroplasty With and Without Tourniquet: Comparative Study
Tourniquet use during total knee arthroplasty (TKA) improves visibility and reduces intraoperative blood loss. However, tourniquet use may also have a negative impact on early recovery of muscle strength and lower extremity…
- Trial name
- NCT04130009
- Testing
- Tourniquet use
- Volunteers
- 70 people
- Sponsor
- Hawler Medical University
Osteoarthritis, Knee
Does Tourniquet Use in Total Knee Replacement Improve Fixation
Although a tourniquet may reduce bleeding during total knee replacement (TKA), and thereby improve fixation, it might also cause complications.
- Trial name
- NCT01470482
- Testing
- No use of tourniquet, Tourniquet
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Per Aspenberg
Arthropathy of Knee, Pain, Joint
Does Tourniquet Use Have an Effect on Pain and Function After Total Knee Arthroplasty
Total knee arthroplasty (TKA) is an effective surgical procedure for reducing knee joint pain and improving the quality of life of patients with advanced knee osteoarthritis.
- Trial name
- NCT04733716
- Testing
- Using Tourniquet
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Umraniye Education and Research Hospital
Pain, Pain After Surgery
Tourniquet Exposure and Risk of Chronic Pain After Severe Limb Trauma
Severe limb trauma often requires the use of a tourniquet to stop life-threatening bleeding. While tourniquets are essential for saving lives, prolonged interruption of blood flow may lead to tissue ischemia, nerve injury, and…
- Conditions
- Pain, Pain After Surgery, Phantom Limb Pain After Amputation, Military Combat Stress Reaction
- Trial name
- TOURNI-PAIN (NCT07475871)
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)