Clinical trials: Tourniquets
Tourniquet-induced Pain, Procedural Pain
Comparison of Ketorolac and Dexmedetomidine as An Adjunct to Lignocaine in Prevention of Tourniquet Induced Pain During Intravenous Regional Anesthesia
This study compared ketorolac and dexmedetomidine when added to lignocaine to prevent pain caused by a tourniquet during intravenous regional anesthesia.
- Trial name
- NCT07878962
- Testing
- Dexmedetomidine, ketorolac, Lidocaine
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Mayo Hospital Lahore
Knee Arthroscopy, Visualization
Intra-Articular Adrenaline Versus Tourniquet in Knee Arthroscopy: A Cohort Study
Arthroscopy has become one of the most commonly performed orthopedic surgeries in the world due to it being a minimally invasive technique. Clear visualization is crucial for both safe and efficient arthroscopic procedures.
- Conditions
- Knee Arthroscopy, Visualization, Adrenaline, Tourniquet
- Trial name
- NCT07813715
- Testing
- Tourniquet, Adrenaline
- Where
- Nepal
- Volunteers
- 169 people
- Sponsor
- Kathmandu University School of Medical Sciences
Tourniquet Hypertension
A Long Axis Approach to the Femoral Artery Block (FAB) for Managing Tourniquet Pain and Hypertension in Below-the-Knee Fracture Surgery
This is a prospective, randomized, double-blind controlled trial evaluating an ultrasound-guided femoral artery block (FAB) using a long-axis in-plane approach compared with a short-axis approach and a control group.
- Trial name
- FAB (NCT07548567)
- Testing
- Femoral artery block - short-axis, Femoral artery block - long-axis, Normal saline injection (control)
- Where
- Greece
- Volunteers
- 84 people
- Sponsor
- National and Kapodistrian University of Athens
Tissue Perfusion, Lower Extremity Surgery
Comparison of the Effects of General Anesthesia and Spinal Anesthesia on Tissue Perfusion in Patients Undergoing Lower Extremity Surgery
This prospective, single-center observational study compares the effects of general anesthesia and spinal anesthesia on tissue perfusion in patients undergoing lower extremity surgery with tourniquet use.
- Conditions
- Tissue Perfusion, Lower Extremity Surgery, Tourniquet-Induced Ischemia-Reperfusion Injury, General Anesthesia
- Trial name
- Perf-LEX (NCT07474480)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Tourniquet Hypertension, Intraoperative Hypertension
Femoral Peri-arterial Local Anesthetic Injection Via Peri-arterial Perineural Catheter Reverses Tourniquet Associated Ischemic Hypertension
The goal of this prospective randomized double-blind study is to determine if an ultrasound guided peri-arterial injection of local anesthetic (LA) superomedially the femoral artery via peripheral nerve catheter reverses ischemic…
- Conditions
- Tourniquet Hypertension, Intraoperative Hypertension, Total Ankle Arthroplasty, Ankle Fusion
- Trial name
- NCT04454203
- Testing
- Mepivacaine, Saline, Perifemoral Injection of Local Anesthetic
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Duke University
Tourniquet Hypertension
Using Lidocaine or Dexmedetomidine to Help Control Blood Pressure Spikes From a Tourniquet During Knee Surgery
Knee pain is very common, and more people are having minor knee surgeries done through a small camera (arthroscopy), often as outpatients.
- Trial name
- torniquet (NCT06936410)
- Testing
- Lidocaine 2% Injectable Solution, Dexmedetomidine HCL Injection
- Where
- Egypt
- Volunteers
- 186 people
- Sponsor
- Cairo University
Pregnancy, Placenta Accrete Spectrum
Impact Tourniquet Conservative Placenta Accreta Neonatal APGAR
Placenta accreta spectrum disorder (PAS) refers to a condition where the placenta fails to separate naturally after childbirth, which can cause significant maternal and neonatal complications, including severe bleeding, leading…
- Conditions
- Pregnancy, Placenta Accrete Spectrum, Tourniquets, Apgar Score
- Trial name
- NCT07412925
- Testing
- Application Of A Tourniquet Around the lower segment of the uterus, Placenta Accreta spectrum conservative management
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Kasr El Aini Hospital
Forearm Surgery, US-Guided Supraclavicular Block
Analgesic Effect of Supraclavicular Block and Interscalene Analgesia Versus an Intercostobrachial Nerve Block Versus PCA in Forearm Surgery
The etiology of tourniquet pain is complex, and the study team hypothesizes that blocking with Interscalene brachial plexus block (ISBPB) is more efficient in decreasing the incidence of tourniquet pain in comparison with other…
- Conditions
- Forearm Surgery, US-Guided Supraclavicular Block, Interscalene Analgesia, Tourniquet Pain
- Trial name
- NCT05602636
- Testing
- bupivacaine, midazolam
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Hemorrhage, Hypovolemic Shock
Efficacy of Prehospital Tourniquet Models for Arterial Occlusion in Upper and Lower Limbs
The goal of this clinical trial is to compare the occlusive capability and mechanical behavior of different commercially available pre-hospital tourniquet models and the results of their application on upper and lower limbs, in…
- Conditions
- Hemorrhage, Hypovolemic Shock, Tourniquets
- Trial name
- TQ-BR (NCT06725602)
- Testing
- TQ - Proximal Application ("high and tight"), TQ - Controlled application (2-3 inches)
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Pain, Postoperative, Total Knee Replacement
Postoperative Pain and Blood Loss of Non-use Compared to Partial-use of a Tourniquet in Bilateral Total Knee Replacement
Postoperative pain and blood loss of non-use compared to partial-use of a tourniquet in bilateral total knee replacement: A Randomized- Control Trial This study aimed to compare the effects of non-use (NTU) and partial-use…
- Conditions
- Pain, Postoperative, Total Knee Replacement, Tourniquet
- Trial name
- TKA (NCT06815445)
- Testing
- None tourniquet
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Tourniquet Pain, Ischemia-reperfusion
The Effect of Prolonged ischemıa and anesthetıc Agents on Oxidative Stress
The goal of this observational study is to learn about the relationship between postoperative pain and tourniquet-induced oxidative damage in adults undergoing orthopedic knee arthroscopy surgery.The goal of this observational…
- Conditions
- Tourniquet Pain, Ischemia-reperfusion, Postoperative Pain, Anesthesia
- Trial name
- NCT06942650
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Duzce University
Arrhythmia, Cardiac, Tourniquet Complications
Effect of Tourniquet Use on ICEB and ICEBc in Upper Extremity Surgeries
In our study, we will examine whether the pressure bandage (tourniquet) used to reduce bleeding during surgery in patients with arm fractures has an effect on heart rhythm.
- Trial name
- NCT06936150
- Testing
- Electrocardiography
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Tourniquets, INTRAVENOUS CATHETER APPLICATION
Effects of Dıfferent Tournıques and Posıtıons on Paın, Anxıety Levels and Applıcatıon Success in Perıpheral Intravenous Catheter Applıcatıon: a Randomızed Controlled Study
Aim: The aim of this study was to investigate the effect of different tourniquet and position on pain, anxiety level and success of peripheral intravenous catheter (PIC) application.
- Trial name
- CATHETER (NCT06862921)
- Testing
- Control
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Tourniquet Palsy
Tourniquet in Total Knee Replacement Short and Long Duration: A Comparative Study
Total knee arthroplasty (TKA) is an effective treatment in severe osteoarthritis. We aim to compare the advantages and disadvantages related to the duration of tourniquet application in TKA surgeries.
- Trial name
- NCT06521593
- Testing
- Applying a tourniquet for either a short or long time during total knee replacement
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Kasr El Aini Hospital
Tourniquet and Outcome After Total Knee Replacement
The Effect of the Tourniquet in Bilateral Total Knee Replacement
This study describes in a randomised controlled trial how the tourniquet influence the outcome af a total knee replacements
- Trial name
- NCT06228651
- Testing
- Tourniquet, The leg without the tourniquet
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Norepinephrine, Glypressin, Tourniquet Deflation, Hypotension
Noradrenaline Versus Glypressin for Prevention of Hypotension After Deflation of Tourniquet in Knee Arthroplasty
Pneumatic tourniquet is usually used in orthopedic surgeries, as it helps to decrease operative bed bleeding, and thus, maintaining a clean and dry surgical field allowing easy and clear identification of the anatomical…
- Trial name
- NCT05774067
- Testing
- Saline, Norepinephrine, glypressin
- Where
- Egypt
- Volunteers
- 135 people
- Sponsor
- Tanta University
Tourniquets, Anesthesia, Conduction
Femoral Artery Block for Reduction of Tourniquet Induced Hypertension
A randomised controlled trial to assess the impact of femoral artery block on the incidence of tourniquet hypertension in patients receiving cruciate ligament surgery with > 30 minutes of tourniquet under combined anaesthesia…
- Conditions
- Tourniquets, Anesthesia, Conduction, Anesthetics, Local, Hypertension
- Trial name
- NCT05954689
- Testing
- Femoral artery block
- Volunteers
- 50 people
- Sponsor
- Hospital da Luz, Portugal
Quadriceps Muscle Atrophy, Tourniquet
Evaluation of Ischemia and Reperfusion Interval With Neuromonitorization in Tourniquet Application
The goal of this clinical trial is to compare two differential tourniquet pressure in lower extremity surgery cases. The main questions it aims to answer are: What are the perioperative neurophysiological effects of ischemia and…
- Conditions
- Quadriceps Muscle Atrophy, Tourniquet, EMG
- Trial name
- NCT05926154
- Testing
- Surgical tourniquet pressure selection
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Istanbul University
Tourniquets
Ischemic Preconditioning and Thiol-disulfide Balance
Various strategies have been proposed to prevent or mitigate the effects of ischemia-reperfusion injury following the use of tourniquets in orthopedic surgery cases.
- Trial name
- NCT05082207
- Testing
- Remote Ischemic Preconditioning
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Bier Block, Dexmedetomidine
A Sequential Allocation Study to Determine the ED50 of Dexmetedomidine as an Adjuvant to Lidocaine Intravenous Regional Anesthesia
Intravenous Regional Anesthesia (IVRA) is an easy and reliable anesthetic technique for hand and forearm surgery. Its use is however limited by the presence of tourniquet pain during the surgery and the absence of postoperative…
- Conditions
- Bier Block, Dexmedetomidine, Tourniquet Pain, Carpal Tunnel
- Trial name
- NCT05342870
- Testing
- Dexmedetomidine
- Volunteers
- 23 people
- Sponsor
- American University of Beirut Medical Center