Clinical trials: Tourniquets
Analgesia
Tourniquet Pain Prevention During Distal Upper Limb Surgery
Post-tourniquet pain remains a common problem. It disturbs the quality of anesthesia during brachial plexus block for distal upper-limb surgery.
- Trial name
- NCT07784426
- Testing
- Selective ultrasound guided Intercostobrachial nerve block, Serratus anterior plane block
- Volunteers
- 90 people
- Sponsor
- Zagazig University
Tourniquet Hypertension
A Long Axis Approach to the Femoral Artery Block (FAB) for Managing Tourniquet Pain and Hypertension in Below-the-Knee Fracture Surgery
This is a prospective, randomized, double-blind controlled trial evaluating an ultrasound-guided femoral artery block (FAB) using a long-axis in-plane approach compared with a short-axis approach and a control group.
- Trial name
- FAB (NCT07548567)
- Testing
- Femoral artery block - short-axis, Femoral artery block - long-axis, Normal saline injection (control)
- Where
- Greece
- Volunteers
- 84 people
- Sponsor
- National and Kapodistrian University of Athens
Arthropathy of Knee Joint
Total Knee Arthroplasty - Accelerated Recovery Without Tourniquet
Introduction: Approximately 7000 total knee replacements (TKAs) are done every year. More than 90% of these knee replacements are performed with the use of bone cement.
- Trial name
- NCT01309035
- Testing
- Total Knee Arthroplasty
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Primary Gonarthrosis
Effects of Tourniquet Applied During Total Knee Replacement Surgery on Patient Hemodynamics and Blood Table
This study was planned to investigate the physiopathology of bradycardia and hypotension that occur in some patients with total knee arthroplasty (TKA) between the ages of 65 and 90 years when the tourniquet, which is routinely…
- Trial name
- NCT07002086
- Testing
- Total knee replacement
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Total Knee Arthroplasty, Tourniquet-Induced Ischemia-Reperfusion Injury
The Effect of Propofol Infusion on Total Antioxidant Status During Tourniquet-Induced Ischemia-Reperfusion Injury
The release of tourniquet produces reactive oxygen species which can cause injury. Propofol is chemically similar to phenol-based free radical scavengers.
- Trial name
- NCT01638624
- Testing
- Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Diskapi Teaching and Research Hospital
Knee Arthroscopy, Visualization
Intra-Articular Adrenaline Versus Tourniquet in Knee Arthroscopy: A Cohort Study
Arthroscopy has become one of the most commonly performed orthopedic surgeries in the world due to it being a minimally invasive technique. Clear visualization is crucial for both safe and efficient arthroscopic procedures.
- Conditions
- Knee Arthroscopy, Visualization, Adrenaline, Tourniquet
- Trial name
- NCT07813715
- Testing
- Tourniquet, Adrenaline
- Where
- Nepal
- Volunteers
- 169 people
- Sponsor
- Kathmandu University School of Medical Sciences
Pregnancy, Placenta Accrete Spectrum
Impact Tourniquet Conservative Placenta Accreta Neonatal APGAR
Placenta accreta spectrum disorder (PAS) refers to a condition where the placenta fails to separate naturally after childbirth, which can cause significant maternal and neonatal complications, including severe bleeding, leading…
- Conditions
- Pregnancy, Placenta Accrete Spectrum, Tourniquets, Apgar Score
- Trial name
- NCT07412925
- Testing
- Application Of A Tourniquet Around the lower segment of the uterus, Placenta Accreta spectrum conservative management
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Kasr El Aini Hospital
Orthopedic Procedures, Tranexamic Acid
Thromboelastogram During Total Knee Replacement
Verify the changes in coagulation system during total knee replacement surgery with tranexamic acid single bolus infusion.
- Trial name
- NCT02373969
- Volunteers
- 30 people
- Sponsor
- Rambam Health Care Campus
Arthroplasty, Replacement, Knee, Acute Kidney Injury
After Surgery Acute Renal Failure Incidence in Total Knee Arthroplasty With and Without Tourniquet
This study analize the incidence of acute renal failure after performing total knee arthroplasty with or without use of tourniquet limb cuff (half of patients for each group) in a randomized clinical trial
- Conditions
- Arthroplasty, Replacement, Knee, Acute Kidney Injury, Tourniquets, Knee Osteoarthritis
- Trial name
- NCT03795805
- Testing
- total knee arthroplasty, Tourniquet limb cuff, Intaarticular lidocain
- Where
- Mexico
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Intravenous Anesthetic Agent Overdose, Hand Injury Wrist
A Comparative Study Between Arm Intravenous Regional Anesthesia Versus Forearm Intravenous Regional Anesthesia in Patients Undergoing Hand and Wrist Surgery
The technique of intravenous regional analgesia using a tourniquet consisting of two cuffs over the upper arm is a well-known procedure, With the tourniquet being conventionally placed over the upper arm, a relatively high dose…
- Trial name
- NCT06448845
- Testing
- Arm intravenous regional anesthesia, Forearm IVRA block
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ain Shams University
Placenta Accreta Spectrum
Comparison Between Cervical Tourniquet and Uterine Artery Ligation Prior to Segmental Resection Approach
The study will compare a modified surgical approach for preserving fertility and minimizing hemorrhage in morbidly adherent placenta during cesarean section with a cervical tourniquet against uterine artery ligation.
- Trial name
- NCT06483724
- Testing
- cervical tourniquet, uterine artery ligation
- Volunteers
- 82 people
- Sponsor
- Minia University
Ischemia Reperfusion Injury
The Effect of Pregabalin Given Preoperatively on the Tourniquet Induced Ischemia-reperfusion
The application of tourniquet is indispensable for a bloodless surgical area in total knee arthroplasty surgery. The release of tourniquet produces reactive oxygen species which can cause injury and then ischemia-reperfusion…
- Trial name
- NCT03482544
- Testing
- Pragabalin
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Baskent University
Arthroplasty, Replacement, Knee, Blood Loss, Surgical
Early Outcome of Simultaneous Bilateral Total Knee Replacement With and Without Tourniquet
This randomized controlled trial compared early outcomes after replacement of both knees during the same operation, with and without tourniquet use.
- Conditions
- Arthroplasty, Replacement, Knee, Blood Loss, Surgical, Pain, Postoperative
- Trial name
- NCT07905495
- Testing
- Simultaneous Bilateral Total Knee Replacement with Tourniquet, Simultaneous Bilateral Total Knee Replacement without Tourniquet
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- Shifa International Hospital
Nerve Block, Pain
Intercostobrachial Nerve Block (ICBN) for Tourniquet Pain: Is it Necessary?
In this study the investigators would like to show that when patients undergo upper limb surgery under supraclavicular brachial plexus block, additional blocking of the Intercostobrachial Nerve Block (ICBN) does not affect the…
- Trial name
- ICBN (NCT03797924)
- Testing
- Receive ICBN with ropivacaine, No ICBN block
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Florida
Total Blood Loss
Evaluation of Blood Loss and Pain in TKA With and Without Pneumatic Tourniquet, A Randomized Controlled Trial
The aim of our study is to determine whether the use of a tourniquet during TKA would affect total measured blood loss , operation time, postoperative complications; hemoglobin concentration; limb swelling and postoperative pain.
- Trial name
- NCT05144425
- Testing
- total knee arthroplasty with and without using pneumatic tourniquet
- Volunteers
- 100 people
- Sponsor
- Assiut University
Hand Injuries With Intravenous Regional Anesthesia
Early Versus Late Deflation of Distal Tourniquet in IVRA With and Without Ketorolac in Hand & Forearm Surgery
Bier block , or intravenous regional anesthesia (IVRA), is a method of anesthesia for upper extremity surgeries. IVRA was first described by August Bier in 1908, and after a period of latency, it began to gain widespread use…
- Trial name
- NCT05234619
- Testing
- Group one ( lidocaine or control LE ) Early deflation, Group two ( lidocaine , ketorolac LKE ) Early deflation, Group three ( lidocaine or control LL ) Late deflation
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sohag University
Sciatic Nerve
Ultrasound Guided Sciatic Nerve Block
The primary purpose of this study is to determine whether the leg positioning or distal tourniquet used during the injection of local anesthetic may decrease the onset time and prolong the duration of analgesia of…
- Trial name
- NCT02688439
- Testing
- Sciatic Nerve block, Leg raised 30°, Distal tourniquet placed on the lower part of the leg
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- NYU Langone Health
Orthopedic Disorder, Hemodynamic Instability
Evaluating The Cardiovascular Effects of Tourniquet Application
The goal of this prospective observational study is to investigate the impact of tourniquet application on cardiac efficiency through the cardiac cycle efficiency parameter and to explore how central regional technique alters…
- Trial name
- NCT06158165
- Testing
- Mostcare (Vytech, Vygon, Padua, Italy)
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Merve Şeker
Amniotic Fluid Embolism, Pulmonary Hypertension
Effect of Tourniquet Binding of Cervical on the Blood Volume of Amniotic Fluid in Cesarean Section
This study was conducted to investigate whether the use of tourniquet after delivery of the fetus could reduce the amount of amniotic fluid entering the bloodstream and thus reduce the incidence of intraoperative adverse events.
- Trial name
- NCT06254092
- Testing
- tourniquet binding of cervical
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Chenzhou
ACL - Anterior Cruciate Ligament Deficiency, ACL Injury
Tourniquet Use in Anterior Cruciate Ligament Repair
The purpose of this study is to assess the intra-operative and post-operative effects of tourniquet use during ACL reconstruction. We hypothesize that: 1.
- Conditions
- ACL - Anterior Cruciate Ligament Deficiency, ACL Injury, ACL Tear
- Trial name
- NCT05931627
- Testing
- Patients undergoing ACL reconstruction with or without a tourniquet
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- OrthoCarolina Research Institute, Inc.