Clinical trials: Tourniquets
Tourniquets, Hypertension
the Effect of Tracleer on Tourniquet-associated Hypertension
Tourniquet is widely used in orthopedic surgery. However, prolonged tourniquet inflation may cause a gradual rise in blood pressure, which named as tourniquet-associated hypertension.
- Conditions
- Tourniquets, Hypertension, Bosentan
- Trial name
- NCT03229694
- Testing
- Tracleer 125Mg Tablet
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xuzhou Medical University
Total Knee Arthroplasty
Impact of Different Perioperative Tourniquets on Blood Loss and Surgeon Satisfaction in Total Knee Arthroplasty
The present study investigates the impact of two different perioperative tourniquets with different closing features on operative blood los, surgical field quality and surgeon satisfaction.
- Trial name
- NCT06947655
- Testing
- VBM Tourniquet, Adaptive Cuff
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bonn
Ankle Fracture
Ankle Fracture Tourniquet Utilization
Lower extremity tourniquet utilization remains a controversial practice during the operative fixation of rotational ankle fractures and is often left to surgeon discretion.
- Trial name
- NCT06863688
- Testing
- Tourniquet, No Tourniquet
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Alex Demers
Hand Injuries, Upper Extremity Injury
Lower Tourniquet Pressure Study
This study design is a prospective, double-blinded, randomized controlled trial evaluating the quality of bloodless surgical field with lower tourniquet pressures based on systolic blood pressure (SBP) compared to standard…
- Trial name
- NCT04994405
- Testing
- Tourniquet Pressure
- Where
- 3 sites in United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Vascular Diseases
Minimal Inflation Tourniquet Pressure Using Induced Hypotension
Limb occlusion pressure (LOP) and arterial occlusion pressure (AOP) are the terms that mean the lowest tourniquet pressure required to stop the arterial blood flow into the limb distal to the cuff.
- Trial name
- NCT04055779
- Testing
- estimation method for arterial occlusion pressure, the limb occlusion pressure
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Flexor Tendon Rupture
Comparison Between Functional Outcomes of Flexor Tendon Repair Under WALANT and Brachial Plexus Block
Although outcomes after flexor tendon repair have reportedly improved with modern treatment, complications are common. Early passive and active motion protocols have improved outcomes of flexor tendon repairs.
- Trial name
- NCT06149962
- Testing
- FLEXOR TENDON REPAIR
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Skin Wound, Complication of Surgical Procedure
Pneumatic Tourniquet Application in Upper Extremity Surgeries
Purpose: This study investigated the effect of cuff pressure and the selection of protective padding material(PPM) on the prevention of skin complications associated with pneumatic tourniquet(PT) application in upper extremity…
- Trial name
- NCT06575088
- Testing
- Standard tourniquet pressure (250 mmHg), Limb occlusion pressure, Cotton Pad
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bursa City Hospital
Injury
Timing of Tourniquet Release
This will be a prospective randomized clinical trial comparing clinical outcome measures in patients who undergo elective upper extremity surgery when tourniquet is dropped prior to closure as opposed to when tourniquet is…
- Trial name
- NCT06576869
- Testing
- Upper extremity orthopedic surgeries.
- Where
- United States
- Volunteers
- 214 people
- Sponsor
- Orlando Health, Inc.
Osteoarthritis, Total Knee Arthroplasty
Tourniquet and Quadricepsforce
The purpose for this study is to investigate the quadriceps (thigh) function preoperatively and 48 hours postoperatively during knee arthroplasty (total replacement of the knee joint) in a randomised study with or without the use…
- Trial name
- NCT01808859
- Testing
- Tourniquet
- Where
- Sweden
- Volunteers
- 64 people
- Sponsor
- Region Skane
Hand Injuries and Disorders
Wide-Awake Local Anesthesia No-Tourniquet (WALANT) Procedures
The goal of this clinical trial is to learn whether a standardized preoperative educational video improves expectation management and the patient experience in adults undergoing Wide-Awake Local Anesthesia No Tourniquet (WALANT)…
- Trial name
- WALANT (NCT07832591)
- Testing
- Preoperative WALANT Educational Video, Traditional Preoperative Counseling
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Carilion Clinic
Carpal Tunnel, Median Nerve Neuralgia
WALANT Procedure in Carpal Tunnel Release
The possible benefits expected from the use of the WALANT procedure are a decrease in intraoperative pain at the surgical site, a decrease in hospitalization time, and a decrease in the time required to lift the anesthesia…
- Conditions
- Carpal Tunnel, Median Nerve Neuralgia, Anesthesia, Local
- Trial name
- NCT04924348
- Testing
- Experimental: WALANT procedure, Active Comparator: Axial ALR, Active Comparator: Truncal ALR
- Where
- France
- Volunteers
- 144 people
- Sponsor
- Elsan
Trauma Injury, Hemorrhage
Tourniquet Training Effectiveness Study
Trauma is the leading cause of death for individuals ages 1-45 years old, within this cohort, and uncontrolled hemorrhage is the leading cause of preventable death.1,2 Tourniquets have been shown to be effective in dramatically…
- Trial name
- TRIAGE (NCT03538379)
- Testing
- Bleeding Control Basic (B-Con) Course
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Extremity Injury
Pre-hospital Tourniquet in Extremity Injury
2.1. Objective: Primary Objective: To compare outcomes of patients with extremity injuries presenting with or without pre-hospital tourniquet placement. 2.2.
- Trial name
- NCT04216225
- Testing
- pre-hospital tourniquet placement
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Methodist Health System
Tourniquet Hypertension, Intraoperative Hypertension
Femoral Peri-arterial Local Anesthetic Injection Decreases Tourniquet Associated Ischemic Hypertension
The purpose of this prospective randomized double-blind study is to determine if the novel technique of ultrasound guided peri-arterial injection of local anesthetic around the femoral artery decreases ischemic hypertension…
- Conditions
- Tourniquet Hypertension, Intraoperative Hypertension, Total Ankle Arthroplasty, Ankle Fusion
- Trial name
- NCT03390426
- Testing
- Mepivacaine, Perifemoral Injection of Local Anesthetic, Saline
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Duke University
Tourniquets, Arthroplasty
Effect of Tourniquet on UKA
There is obviously a lack of evidence regarding the risk-benefit ratio of a thigh tourniquet in unicondylar knee arthroplasty (UKA).
- Trial name
- NCT02465684
- Testing
- unicondylar knee arthroplasty
- Volunteers
- 30 people
- Sponsor
- Medical University Innsbruck
Knee Osteoarthritis
Effects of Tourniquet Use on Physical Function and Performance in Primary Total Knee Arthroplasty
Background: Osteoarthritis (OA) is the most common joint disease that causes symptomatic health problems in the elderly population.
- Trial name
- NCT01891266
- Testing
- Non-tourniquet assisted TKA, Tourniquet assisted TKA
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Southern Denmark
Traumatic Hemorrhage
LAVA TQ Doppler Functionality Study
This is a single-blinded, randomized clinical trial to determine if the Layperson Audiovisual Assist tourniquet's (LAVA TQ) ability to occlude arterial blood flow is non-inferior to that of the Combat Application Tourniquet (CAT).
- Trial name
- NCT05504733
- Testing
- Layperson Audiovisual Assist Tourniquet (LAVA TQ), Combat Application Tourniquet
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Tourniquet Placement, Wound Packing
Effectiveness of the Adding High Fidelity Simulation to the Bleeding Control Course in Regards to Proper Tourniquet Placement Amongst School Personnel
This is a joint project by the White Plains School District and White Plains Hospital regarding the training of over 66 school personnel regarding the American College of Surgeons (ACS) "Stop the Bleed" campaign for mass casualty…
- Trial name
- NCT04293211
- Testing
- Simulation
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- White Plains Hospital
Abdominal Myomectomy, Blood Loss
Methods to Reduce Blood Loss in Abdominal Myomectomy
The aim of the study is to compare the effectiveness of a single preoperative dose of vaginal misoprostol, intraoperative oxytocin infusion, IV carbetocin and pericervical tourniquet for the reduction of blood loss during of…
- Trial name
- NCT04595812
- Testing
- Misoprostol 200mcg Tab vaginal, Oxytocin, Carbetocin
- Volunteers
- 120 people
- Sponsor
- Cairo University
Hypotension After Spinal Anesthesia
Preoperative Oral Heptaminol Hydrochloride in Preventing Hypotension After Spinal Anesthesia
Methodologies and approaches have been implemented with differing degrees of success to prevent neuraxial hypotension. Currently utilized approaches to prevent hypotension during spinal anesthetic administration consist of…
- Trial name
- NCT06564935
- Testing
- Heptaminol Hydrochloride
- Volunteers
- 160 people
- Sponsor
- Cairo University