Clinical trials: Toxicant Exposure
Tobacco-Related Carcinoma
Hookah Additive Research to Inform Product Standards
This clinical trial evaluates how the content of waterpipe (WP) tobacco affects the appeal, puffing behavior, and toxicity of WP tobacco smoking.
- Trial name
- HARPS (NCT05453773)
- Testing
- Questionnaire Administration, Tobacco Smoking
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Inflammation, Oxidative Stress
Reduction of Exposure, Inflammation, and Oxidative Stress Following at Least 2 Years of Switching to THS Use Compared to Cigarette Smoking
This is a cross-sectional 3-group study with subjects enrolled and matched by region (Asia, Europe), age, sex, and average daily product consumption over the last 2 years as self-reported.
- Conditions
- Inflammation, Oxidative Stress, Smoking, Smoking Abstinence
- Trial name
- NCT05385055
- Testing
- THS use, Cigarette smoking, Smoking abstinence
- Where
- 37 sites in Bulgaria, Czechia and 4 more
- Volunteers
- 974 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Toxicant Exposure
Effects Among Smokers Who Use and Do Not Use E-Cigarettes
This study compares effects among Latino and African American cigarette smokers who use e-cigarettes with those who continue smoking as usual.
- Trial name
- NCT03511001
- Testing
- E-Cigarette Vs. Smoking as Usual
- Where
- 2 sites in United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- California State University, San Marcos
Smokeless Tobacco Use, Tobacco Dependence
Novel Determinants and Measures of Smokeless Tobacco Use: Study 1
The extent of toxicity varies considerably across different brands of smokeless tobacco (ST) products and data suggest that greater toxicity may result in greater health risks.
- Trial name
- NCT01067586
- Where
- 3 sites in United States
- Volunteers
- 359 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking, Hookah, Waterpipe Smoking
The Impact of Waterpipe Tobacco Flavors on Waterpipe Smoking Intentions, Perceptions, Patterns, and Toxicant Exposure
The overall aim of the current study is to determine if flavorings contribute to the initiation and maintenance of waterpipe (WP) smoking and also influence how a WP is smoked, which has implications for both risk of dependence…
- Trial name
- NCT03232827
- Testing
- Flavored-Sweetened Waterpipe Tobacco, Unflavored-sweetened waterpipe tobacco, Unflavored-very low sweetened waterpipe tobacco
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Waterpipe Size
Effect of Waterpipe Size on Smoking Behavior and Exposures
The goal of this clinical trial is to learn how waterpipe (WP) size affects smoking behavior, toxicant exposure, and subjective experiences in young adult WP smokers (ages 21-39).
- Trial name
- NCT05705375
- Testing
- Waterpipe size
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Electronic Nicotine Delivery System Flavors
Potential Effects of Electronic Nicotine Delivery System Flavor Regulations on African American Menthol Smokers
This study aims to better understand how the availability of electronic nicotine delivery system (aka electronic cigarettes) flavors (e.g., menthol, tobacco) impacts tobacco use behaviors, toxicant exposure, and abuse liability…
- Trial name
- RVA Flavors (NCT05023096)
- Testing
- Tobacco product administration and assessment
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University