Clinical trials: Trace Elements
Cardiovascular Disease Prevention
Impact of a Nutritional Supplement on Metabolic Health
There are prevalent micronutrient and fiber deficiencies in a significant proportion of US population, particularly among the overweight or obese.
- Trial name
- CHORIBar (NCT02239198)
- Testing
- Nutrition bar
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Anabolic Response to Mycoprotein and Micronutrient Ingeston
Mycoprotein and Muscle Protein Synthetic Response
Dietary protein is vital for the preservation of health and optimal adaptation to training. However, traditional animal proteins come with a number of economic, environmental, and ethical issues.
- Trial name
- PIMP (NCT04084652)
- Testing
- Mycoprotein ingestion
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Anemia, Iron-deficiency
Effectiveness of Selling Micronutrient Sprinkles in Rural Kenya
The purpose of the study is to evaluate the effectiveness of household-based distribution of evidence-based health products and to measure the health impact of these combined interventions on a population basis.
- Trial name
- NICHE (NCT01088958)
- Testing
- Micronutrient powders (Sprinkles)
- Where
- Kenya
- Volunteers
- 7,200 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Nutrient Deficiency
Antenatal Multiple Micronutrient Supplementation (MMS) in Indonesia
The objective of this research is to understand how antenatal multiple micronutrient supplements (MMS) can be effectively implemented and scaled within the Indonesian national health system context to support improved maternal…
- Trial name
- NCT06225791
- Testing
- MMS (90x2) + BCC or expanded BCC, MMS (180x1) + BCC or expanded BCC
- Where
- Indonesia
- Volunteers
- 5,384 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Folate Deficiency, Vitamin B 12 Deficiency
Effectiveness of Fortification With Folic Acid and Vitamin B12 Among Teenage Girls
Folic acid and vitamin B12 play an interdependent role in key cellular processes, namely deoxyribonucleic acid synthesis, cell division, red blood cell formation, and nervous system myelination.
- Conditions
- Folate Deficiency, Vitamin B 12 Deficiency, Anemia, Megaloblastic, Cognitive Development
- Trial name
- NCT06100146
- Testing
- Folic acid and vitamin B12 fortified flour, Unfortified cereal flour
- Where
- 2 sites in Ethiopia
- Volunteers
- 472 people, healthy volunteers welcome
- Sponsor
- University Ghent
Child Nutrition Disorders
Effect of Behavior Change Communication About Improved Micronutrient Intake on Nutritional Status and Academic Performance of School Age Children in Meskan District, Gurage Zone, South Ethiopia
A cluster randomized controlled trial was chosen to exploit the robustness of this design to help ascertain the efficacy of the BCC intervention compared to the routine dietary practice.
- Trial name
- BCC (NCT02956941)
- Testing
- BCC on Essential Nutrition and Hygiene Actions (ENHAs)
- Where
- Ethiopia
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Jimma University
Iron-deficiency, Vitamin A Deficiency
Sub Regional Micronutrient Survey in Ethiopia
To conduct a sub-regional micronutrient survey (SRMNS) assessing the prevalence of vitamin A, Zn, and Fe status in the country
- Conditions
- Iron-deficiency, Vitamin A Deficiency, Zinc Deficiency
- Trial name
- NCT03353662
- Testing
- Women of Gamo Gofa, Children of Gamo Gofa, Women of West Gojjam
- Where
- 2 sites in Ethiopia, Switzerland
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Healthy
Content, Bioavailability and Health Effects of Trace Elements and Bioactive Components in Organic Agricultural Systems
Trace elements, bioactive secondary metabolites and vitamins are among the most important quality parameters in plants. Yet, very little information is available on their content, bioavailability and health effects of organically…
- Trial name
- OrgTrace (NCT00738166)
- Testing
- Organic or conventional diet, Diet (organic or conventional)
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Adherence, Pregnancy
Evaluation of an Intervention for Optimizing Pregnant Women's Adherence to Maternal Multiple Micronutrients Supplements
In collaboration with the Federal Government of Nigeria and Bauchi State, Nutrition International (NI) conducted a three-year implementation research study to assess whether adherence solutions - developed through a…
- Trial name
- NCT07644780
- Testing
- Implementation Approaches
- Where
- 3 sites in Nigeria
- Volunteers
- 2,601 people, healthy volunteers welcome
- Sponsor
- Nutrition International
Pregnancy Related
Multiple Micronutrient Supplementation (MMS) vs IFA Acceptability Crossover Trial
This is an open-label individually randomized mixed methods cross-over trial to assess acceptability, preference, and side effects of IFA formulations with 60 mg of iron to MMS formulations with 60 mg of iron.
- Trial name
- MIFA-ACT (NCT06069856)
- Testing
- Iron Folic Acid Tablets with 60 mg of iron, Multiple Micronutrient Supplements with 60 mg of elemental iron
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- George Washington University
Malnutrition
Acceptability of Zinc-fortified Lipid-based Nutrient Supplements
The purpose of the study is to assess the acceptability of the two lipid-based nutrient supplement (LNS) formulations containing no zinc and a high amount of zinc (10 mg zinc / 20 g dose of LNS).
- Trial name
- NCT00944814
- Testing
- LNS with zinc, LNS without zinc
- Where
- Burkina Faso
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Plasma Volume, Micronutrients
Cyclic Variation in Micronutrient Concentrations and Plasma Volume
The overall goal of this study is to examine the influence of the menstrual cycle on micronutrient concentrations and plasma volume in healthy, reproductive-age women with regular cycles.
- Conditions
- Plasma Volume, Micronutrients, Menstrual Cycle
- Trial name
- NCT03422809
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Alison Gernand
Child Malnutrition, Infant Morbidity
Effectiveness of Nutritional Supplementation in Preventing Malnutrition in Children With Infection in Karamoja, Uganda
The purpose of this study is to determine whether 14 days nutritional supplementation with Ready to use therapeutic Food (RUTF) or micronutrients alone to children having an infection will prevent malnutrition and reduce the…
- Trial name
- MSF-nutcon03 (NCT01497236)
- Testing
- Dietary Supplement: Nutrition supplement with RUTF or MNP
- Where
- Uganda
- Volunteers
- 2,202 people, healthy volunteers welcome
- Sponsor
- Medecins Sans Frontieres, Spain
Child Malnutrition
Acceptability of a Multiple Micronutrient-Fortified Lipid-Based Nutrient Supplement for Children Under Two in Cambodia
The purpose of this trial is to evaluate the acceptability of the LNS to women and their children aged 12-17 months in comparison to Corn Soy Blend++, and Sprinkles added to borbor (white rice porridge, which is the traditional…
- Trial name
- NCT02257437
- Testing
- LNS snack, Corn-soy blend ++ (CSB++), Sprinkles
- Where
- Cambodia
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche pour le Developpement, Cambodia
Birth Weight, Miscarriage
Micronutrient Supplementation Before and During 1st Pregnancy to Improve Birth Outcomes (JiVitA-5)
The purpose of this cluster-randomized trial is to evaluate the efficacy of daily, multiple micronutrient (MM) supplement versus identical placebo use among nulligravid, recently married women, starting preconceptionally through…
- Conditions
- Birth Weight, Miscarriage, Small-for-gestational Age, Preterm Birth
- Trial name
- JiVitA-5 (NCT03921177)
- Testing
- Multiple micronutrient supplement
- Where
- Bangladesh
- Volunteers
- 9,859 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Malaria
Micronutrients and Child Health Study
The purpose of this study is to determine to what extent supplementation with zinc and other micronutrients are efficacious in preventing malaria in young Tanzanian children.
- Trial name
- MACH (NCT00623857)
- Testing
- Zinc, Vitamins and minerals other than zinc, Vitamins plus zinc and other minerals
- Where
- Tanzania
- Volunteers
- 612 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Asthma, Wheezing
Evaluation of Toxic Metals, Trace Elements and Total Antioxidant Activity in Children With Recurrent Wheezing
The purpose of this study is to evaluate hair trace elements and toxic metals and plasma total antioxidant activity in children with recurrent wheezing and to evaluate whether these toxic metals and trace elements have any impact…
- Trial name
- NCT00749528
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Kecioren Education and Training Hospital
Lung Cancer
Study of Lung Cancer in Appalachian Kentucky: The Role of Environmental Carcinogens
This is a research study about the relationship between lung cancer and environmental risk factors. The purpose of this study is to try to understand the effects of trace elements such as arsenic and chromium, as well as radon on…
- Trial name
- NCT01648166
- Testing
- Environmental sampling
- Where
- United States
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Susanne Arnold
Micronutrient Deficiencies
The Effect of Micronutrient Supplementation on Nutrition Status and Well-being
Inadequate micronutrient status poses a significant challenge in Sub-Saharan African countries, including Ghana, and affects various demographics.
- Trial name
- NEXUS (NCT07031973)
- Testing
- Active Effervescent Powder, Nutrition training and healthy lifestyle coaching
- Where
- Ghana
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- InnoNext Sarl
Pregnancy Related
Increasing Access to Multiple Micronutrient Supplementation - A Pilot Intervention at up to 15 Clinics in Botswana
The purpose of this study is to pilot a clinic-level supplementation intervention at up to 15 antenatal clinics throughout Botswana.
- Trial name
- NCT05703373
- Testing
- Multiple Micronutrient Supplement
- Where
- 13 sites in Botswana
- Volunteers
- 1,210 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania